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Original Articles

First Synthesis of Thienopyrazole Thioglycosides

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Pages 345-356 | Received 20 Mar 2008, Accepted 29 May 2008, Published online: 07 Aug 2008

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Mamdouh A. Abu-Zaied, Galal H. Elgemeie, Fathi T. Halaweish & Sherif F. Hammad. (2022) Synthesis of novel pyridine and pyrimidine thioglycoside phosphoramidates for the treatment of COVID-19 and influenza A viruses. Nucleosides, Nucleotides & Nucleic Acids 41:9, pages 851-877.
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Mamdouh A. Abu-Zaied, Galal H. Elgemeie & Nashwa M. Mahmoud. (2021) Synthesis of novel pyrimidine thioglycosides as structural analogs of favipiravir (avigan) and their antibird flu virus activity. Nucleosides, Nucleotides & Nucleic Acids 40:3, pages 336-356.
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Mamdouh A. Abu-Zaied & Galal H. Elgemeie. (2019) Novel synthesis of new pyrazole thioglycosides as pyrazomycin analogues. Nucleosides, Nucleotides & Nucleic Acids 38:5, pages 374-389.
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Galal H. Elgemeie, Mamdouh A. Abu-Zaied & Abdel-Tawab H. Mossa. (2019) Novel Synthesis and Biological Evaluation of the First Pyrazole Thioglycosides as Pyrazofurin Analogues. Nucleosides, Nucleotides & Nucleic Acids 38:3, pages 183-202.
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Galal H. Elgemeie, Mamdouh A. Abu-Zaied & Galal A. Nawwar. (2018) First novel synthesis of triazole thioglycosides as ribavirin analogues. Nucleosides, Nucleotides & Nucleic Acids 37:2, pages 112-123.
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Mamdouh A. Abu-Zaied & Galal H. Elgemeie. (2017) Synthesis of the first novel pyrazole thioglycosides as deaza ribavirin analogues. Nucleosides, Nucleotides & Nucleic Acids 36:12, pages 713-725.
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Galal H. Elgemeie & Mamdouh A. Abu-Zaied. (2017) Heterocyclic thioglycosides in carbohydrate research: Synthesis of thiophene thioglycosides. Nucleosides, Nucleotides & Nucleic Acids 36:8, pages 511-519.
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Galal H. Elgemeie & Ayman B. Farag. (2017) Design, synthesis, and in vitro anti-hepatocellular carcinoma of novel thymine thioglycoside analogs as new antimetabolic agents. Nucleosides, Nucleotides & Nucleic Acids 36:5, pages 328-342.
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Galal H. Elgemeie, Ali M. Salah, Nermeen S. Abbas, Hoda A. Hussein & Reham A. Mohamed. (2017) Pyrimidine non-nucleoside analogs: A direct synthesis of a novel class of N-substituted amino and N-sulfonamide derivatives of pyrimidines. Nucleosides, Nucleotides & Nucleic Acids 36:3, pages 213-223.
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Galal Elgemeie, Nahed Fathy, Wafaa Zaghary & Ayman Farag. (2017) S-glycosides in medicinal chemistry: Novel synthesis of cyanoethylene thioglycosides and their pyrazole derivatives. Nucleosides, Nucleotides & Nucleic Acids 36:3, pages 198-212.
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Galal H. Elgemeie, Ali M. Salah, Nermeen S. Abbas, Hoda A. Hussein & Reham A. Mohamed. (2017) Nucleic acid components and their analogs: Design and synthesis of novel cytosine thioglycoside analogs. Nucleosides, Nucleotides & Nucleic Acids 36:2, pages 139-150.
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Galal Elgemeie, Mamdouh Abu-Zaied & Rasha Azzam. (2016) Antimetabolites: A First Synthesis of a New Class of Cytosine Thioglycoside Analogs. Nucleosides, Nucleotides & Nucleic Acids 35:4, pages 211-222.
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Galal Elgemeie, Mamdouh Abou-Zeid, Shahinaz Alsaid, Ali Hebishy & Hanaa Essa. (2015) Novel Nucleoside Analogues: First Synthesis of Pyridine-4-Thioglycosides and Their Cytotoxic Evaluation. Nucleosides, Nucleotides & Nucleic Acids 34:10, pages 659-673.
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G. H. Elgemeie & N. M. Saber. (2015) Synthesis and in Vitro Anti-Tumor Activity of A New Class of Acyclic Thioglycosides. Nucleosides, Nucleotides & Nucleic Acids 34:7, pages 463-474.
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Articles from other publishers (11)

Galal H. Elgemeie & Reham A. Mohamed-Ezzat. 2022. New Strategies Targeting Cancer Metabolism. New Strategies Targeting Cancer Metabolism 547 611 .
Mohamed Ramadan, Ashraf A. Aly, Lamiaa E. Abd El-Haleem, Mohammed B. Alshammari & Stefan Bräse. (2021) Substituted Pyrazoles and Their Heteroannulated Analogs—Recent Syntheses and Biological Activities. Molecules 26:16, pages 4995.
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Mamdouh A. Abu-Zaied, Galal H. Elgemeie & Nashwa M. Mahmoud. (2021) Anti-Covid-19 Drug Analogues: Synthesis of Novel Pyrimidine Thioglycosides as Antiviral Agents Against SARS-COV-2 and Avian Influenza H5N1 Viruses. ACS Omega 6:26, pages 16890-16904.
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Mamdouh Attia Abu-Zaied, Sherif F. Hammad, Fathi T. Halaweish & Galal Hamza Elgemeie. (2020) Sofosbuvir Thio-analogues: Synthesis and Antiviral Evaluation of the First Novel Pyridine- and Pyrimidine-Based Thioglycoside Phosphoramidates. ACS Omega 5:24, pages 14645-14655.
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Tamer Nasr, Samir Bondock, Tamer M. Ibrahim, Walid Fayad, Ahmed B. Ibrahim, Neveen A. AbdelAziz & Tamer M. Sakr. (2020) New acrylamide-sulfisoxazole conjugates as dihydropteroate synthase inhibitors. Bioorganic & Medicinal Chemistry 28:9, pages 115444.
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Mamdouh A. Abu-Zaied & Galal H. Elgemeie. (2017) Thiazoles in glycosylation reactions: Novel synthesis of thiazole thioglycosides. Heteroatom Chemistry 28:6, pages e21404.
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Adel M. Kamal El-Dean, Remon M. Zaki & Abdullah Y. Abdulrazzaq. (2015) A convenient synthesis and biological activity of novel thieno[2,3-c]pyrazole compounds as antimicrobial and anti-inflammatory agents. Russian Journal of Bioorganic Chemistry 41:1, pages 97-104.
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Galal H. Elgemeie, Mamdouh Abouzeid & Peter G. Jones. (2015) Crystal structure of 4-{[(cyanoimino)(methylsulfanyl)methyl]amino}-1,5-dimethyl-2-phenyl-2,3-dihydro-1 H -pyrazol-3-one . Acta Crystallographica Section E Crystallographic Communications 71:1, pages 104-106.
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El Sayed H. El Ashry, Aly A. Aly, Mohammed R. Amer, Muhammad R. Shah & Seik W. Ng. (2011) Synthesis and X-ray analysis of butyl and glycosyl (2-arylamino-4,4-dimethyl-6-oxocyclohex-1-ene)carbodithioates and their possible cyclization to 2-thioxo-6,7-dihydro-1H-benzo[d][1,3]thiazin-5(2H)-one derivatives. Carbohydrate Research 346:2, pages 169-176.
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Galal H. Elgemeie, Nahed M. Fathy, Sayed Shaarawi & Peter G. Jones. (2010) trans -Tetraaquabis{( E )-2-cyano-1-[(ethoxycarbonyl)methylsulfanyl]-2-(1-naphthylaminocarbonyl)ethene-1-thiolato}calcium(II) diethyl ether disolvate . Acta Crystallographica Section E Structure Reports Online 66:5, pages m554-m555.
Crossref
Galal H. Elgemeie, Wafaa A. Zaghary, Tamer M. Nasr & Kamelia M. Amin. (2008) ChemInform Abstract: First Synthesis of Thienopyrazole Thioglycosides.. ChemInform 40:3.
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