128
Views
42
CrossRef citations to date
0
Altmetric
NEW DRUGS

Histone Deacetylase Inhibitors in Cancer Therapy

, M.D.
Pages 521-527 | Published online: 11 Jun 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Walter H Meisen & Balveen Kaur. (2013) How can we trick the immune system into overcoming the detrimental effects of oncolytic viral therapy to treat glioblastoma?. Expert Review of Neurotherapeutics 13:4, pages 341-343.
Read now
Jasmine Zain & Kathryn Sawey. (2012) Peripheral T cell lymphoma: clinical utility of romidepsin. Blood and Lymphatic Cancer: Targets and Therapy 2, pages 109-115.
Read now
Jeffrey Knipstein & Lia Gore. (2011) Entinostat for treatment of solid tumors and hematologic malignancies. Expert Opinion on Investigational Drugs 20:10, pages 1455-1467.
Read now

Articles from other publishers (39)

Merve Özel, Gülden Başkol, Mevlüt Başkol, Fatma Güneş, Çiğdem Uçar, Büşra Nur Doğru & Hilal Akalın. (2022) SAHA induce hippo pathway in CCA cells without increasing cell proliferation. Molecular Biology Reports 49:5, pages 3649-3656.
Crossref
Moran Sun, Jinling Qin, Yingying Kang, Yixin Zhang, Mengyu Ba, Hua Yang, Yongtao Duan & Yongfang Yao. (2022) 2-Methoxydiol derivatives as new tubulin and HDAC dual-targeting inhibitors, displaying antitumor and antiangiogenic response. Bioorganic Chemistry 120, pages 105625.
Crossref
Han-Gyu Chang, Yong-Hyeon Choi, JinWoo Hong, Joung-Woo Choi, A-Rum Yoon & Chae-Ok Yun. (2021) GM101 in Combination with Histone Deacetylase Inhibitor Enhances Anti-Tumor Effects in Desmoplastic Microenvironment. Cells 10:11, pages 2811.
Crossref
Shan Li, Yu Ding, Miaomiao Chen, Ya Chen, Johannes Kirchmair, Zihao Zhu, Song Wu & Jie Xia. (2020) HDAC3i‐Finder: A Machine Learning‐based Computational Tool to Screen for HDAC3 Inhibitors. Molecular Informatics 40:3, pages 2000105.
Crossref
Qingwei Zhang, Guili Xu, Ya Bao, Minru Jiao & Jianqi Li. (2020) Design, Synthesis, and Biological Evaluation of Dual c-Met/HDAC Inhibitors Bearing 2-Aminopyrimidine Scaffold. Pharmaceutical Fronts 02:03, pages e143-e149.
Crossref
Qingwei Zhang, Guili Xu, Ya Bao, Minru Jiao & Jianqi Li. (2020) Design, Synthesis, and Biological Evaluation of Dual c-Met/HDAC Inhibitors Bearing 2-Aminopyrimidine Scaffold. Pharmaceutical Fronts 02:02, pages e117-e123.
Crossref
Min Hu, Najealicka Armstrong, Edward Seto, Wenwei Li, Fanxiu Zhu, Paul C. Wang & Qiyi Tang. (2019) Sirtuin 6 Attenuates Kaposi's Sarcoma-Associated Herpesvirus Reactivation by Suppressing Ori-Lyt Activity and Expression of RTA. Journal of Virology 93:7.
Crossref
Carole Achard, Abera Surendran, Marie-Eve Wedge, Guy Ungerechts, John Bell & Carolina S. Ilkow. (2018) Lighting a Fire in the Tumor Microenvironment Using Oncolytic Immunotherapy. EBioMedicine 31, pages 17-24.
Crossref
Sugathan Praseetha, Srinivas Bandaru, Anuraj Nayarisseri & Sivanpillai Sureshkumar. (2016) Pharmacological Analysis of Vorinostat Analogues as Potential Anti-tumor Agents Targeting Human Histone Deacetylases: an Epigenetic Treatment Stratagem for Cancers. Asian Pacific Journal of Cancer Prevention 17:3, pages 1571-1576.
Crossref
Irina N. Gaisina, Werner Tueckmantel, Andrey Ugolkov, Sida Shen, Jessica Hoffen, Oleksii Dubrovskyi, Andrew Mazar, Renee A. Schoon, Daniel Billadeau & Alan P. Kozikowski. (2016) Identification of HDAC6-Selective Inhibitors of Low Cancer Cell Cytotoxicity. ChemMedChem 11:1, pages 81-92.
Crossref
Prakash Satwani, Sejal Bavishi, Aniket Saha, Frances Zhao, Janet Ayello, Carmella van de Ven, Yaya Chu & Mitchell S. Cairo. (2014) Upregulation of NKG2D ligands in acute lymphoblastic leukemia and non-Hodgkin lymphoma cells by romidepsin and enhanced in vitro and in vivo natural killer cell cytotoxicity. Cytotherapy 16:10, pages 1431-1440.
Crossref
Pravin Bhansali, Christin L. Hanigan, Lalith Perera, Robert A. CaseroJr.Jr. & L.M. Viranga Tillekeratne. (2014) Synthesis and biological evaluation of largazole analogues with modified surface recognition cap groups. European Journal of Medicinal Chemistry 86, pages 528-541.
Crossref
Charles S. Ward. (2014) Autism’s cancer connection: The anti-proliferation hypothesis and why it may matter. Medical Hypotheses 82:1, pages 26-35.
Crossref
Lingling Zhao, Yuhong Xiang, Jinglin Song & Zhuoyong Zhang. (2013) A novel two-step QSAR modeling work flow to predict selectivity and activity of HDAC inhibitors. Bioorganic & Medicinal Chemistry Letters 23:4, pages 929-933.
Crossref
Hak Jae Kim, Tae Hwan Kim, Won Sik Seo, Sun Dong Yoo, Il Han Kim, Sang Hoon Joo, Soyoung Shin, Eun-Seok Park, Eun Sook Ma & Beom Soo Shin. (2012) Pharmacokinetics and tissue distribution of psammaplin A, a novel anticancer agent, in mice. Archives of Pharmacal Research 35:10, pages 1849-1854.
Crossref
Christopher A. Alvarez-Breckenridge, Jianhua Yu, Richard Price, Min Wei, Yan Wang, Michal O. Nowicki, Yoonhee P. Ha, Stephen Bergin, Christine Hwang, Soledad A. Fernandez, Balveen Kaur, Michael A. Caligiuri & E. Antonio Chiocca. (2012) The Histone Deacetylase Inhibitor Valproic Acid Lessens NK Cell Action against Oncolytic Virus-Infected Glioblastoma Cells by Inhibition of STAT5/T-BET Signaling and Generation of Gamma Interferon. Journal of Virology 86:8, pages 4566-4577.
Crossref
Patrick M. Woster & Robert A. Casero, Jr. 2011. Polyamine Drug Discovery. Polyamine Drug Discovery 104 134 .
Michael J. Powell, Vladimir M. Popov, Xiang Wang, Steven B. McMahon, Alexander Mazo & Richard G. Pestell. 2011. Cancer Epigenetics. Cancer Epigenetics 113 144 .
José García, Gianluigi Franci, Raquel Pereira, Rosaria Benedetti, Angela Nebbioso, Fátima Rodríguez-Barrios, Hinrich Gronemeyer, Lucia Altucci & Angel R. de Lera. (2011) Epigenetic profiling of the antitumor natural product psammaplin A and its analogues. Bioorganic & Medicinal Chemistry 19:12, pages 3637-3649.
Crossref
Qiong Xu, Rong Lu, Zhi‐Feng Zhu, Jun‐Qiang Lv, Li‐Juan Wang, Wen Zhang, Jin‐Wei Hu, Jie Meng, Gang Lin & Zhi Yao. (2010) Effects of tyroservatide on histone acetylation in lung carcinoma cells. International Journal of Cancer 128:2, pages 460-472.
Crossref
Shiv K. Sharma, Yu Wu, Nora Steinbergs, Michael L. Crowley, Allison S. Hanson, Robert A. CaseroJr.Jr. & Patrick M. Woster. (2010) (Bis)urea and (Bis)thiourea Inhibitors of Lysine-Specific Demethylase 1 as Epigenetic Modulators. Journal of Medicinal Chemistry 53:14, pages 5197-5212.
Crossref
Artem Melman. 2009. PATAI'S Chemistry of Functional Groups. PATAI'S Chemistry of Functional Groups.
Yuqing Dong & Sige Zou. 2010. Epigenetics of Aging. Epigenetics of Aging 51 75 .
Ryuya Yamanaka & Hideyuki Saya. (2009) Molecularly targeted therapies for glioma. Annals of Neurology 66:6, pages 717-729.
Crossref
Lisa M. Giammona, Swapna Panuganti, Jan M. Kemper, Pani A. Apostolidis, Stephan Lindsey, Eleftherios T. Papoutsakis & William M. Miller. (2009) Mechanistic studies on the effects of nicotinamide on megakaryocytic polyploidization and the roles of NAD+ levels and SIRT inhibition. Experimental Hematology 37:11, pages 1340-1352.e3.
Crossref
Xujun Ma, Hany H. Ezzeldin & Robert B. Diasio. (2009) Histone Deacetylase Inhibitors. Drugs 69:14, pages 1911-1934.
Crossref
Christopher Alvarez-Breckenridge, Balveen Kaur & E. Antonio Chiocca. (2009) Pharmacologic and Chemical Adjuvants in Tumor Virotherapy. Chemical Reviews 109:7, pages 3125-3140.
Crossref
Wei Zhang, Michael Peyton, Yang Xie, Junichi Soh, John D. Minna, Adi F. Gazdar & Eugene P. Frenkel. (2009) Histone Deacetylase Inhibitor Romidepsin Enhances Anti-Tumor Effect of Erlotinib in Non-small Cell Lung Cancer (NSCLC) Cell Lines. Journal of Thoracic Oncology 4:2, pages 161-166.
Crossref
Akihiro Otsuki, Ankita Patel, Kazue Kasai, Masataka Suzuki, Kazuhiko Kurozumi, E Antonio Chiocca & Yoshinaga Saeki. (2008) Histone Deacetylase Inhibitors Augment Antitumor Efficacy of Herpes-based Oncolytic Viruses. Molecular Therapy 16:9, pages 1546-1555.
Crossref
Sheeba Varghese, Thulani Senanayake, Tracey Murray-Stewart, Kim Doering, Alison Fraser, Robert A. CaseroJr.Jr. & Patrick M. Woster. (2008) Polyaminohydroxamic Acids and Polyaminobenzamides as Isoform Selective Histone Deacetylase Inhibitors. Journal of Medicinal Chemistry 51:8, pages 2447-2456.
Crossref
Rebecca L. Brown & Ezra E.W. Cohen. (2008) Novel approaches in the treatment of thyroid cancer. Update on Cancer Therapeutics 3:1, pages 1-11.
Crossref
Emily A Vucic, Carolyn J Brown & Wan L Lam. (2008) Epigenetics of cancer progression. Pharmacogenomics 9:2, pages 215-234.
Crossref
Daniela D. Rosa, Gustavo Ismael, Lissandra Dal Lago & Ahmad Awada. (2008) Molecular-targeted therapies: Lessons from years of clinical development. Cancer Treatment Reviews 34:1, pages 61-80.
Crossref
Yong-Uk Kwon & Thomas Kodadek. (2008) Encoded combinatorial libraries for the construction of cyclic peptoid microarrays. Chemical Communications:44, pages 5704.
Crossref
Leslie Robinson-Bostom, John Kawaoka, Reena Rupani & Charles J. McDonald. 2008. Abeloff's Clinical Oncology. Abeloff's Clinical Oncology 625 640 .
Carl E. Freter & Michael C. Perry. 2008. Abeloff's Clinical Oncology. Abeloff's Clinical Oncology 449 483 .
Ann M. Gillenwater, Meiling Zhong & Reuben Lotan. (2007) Histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis through both mitochondrial and Fas (Cd95) signaling in head and neck squamous carcinoma cells. Molecular Cancer Therapeutics 6:11, pages 2967-2975.
Crossref
James R. Whittle, Michael J. Powell, Vladimir M. Popov, L. Andrew Shirley, Chenguang Wang & Richard G. Pestell. (2007) Sirtuins, nuclear hormone receptor acetylation and transcriptional regulation. Trends in Endocrinology & Metabolism 18:9, pages 356-364.
Crossref
Nino Keshelava, Elai Davicioni, Zesheng Wan, Lingyun Ji, Richard Sposto, Timothy J. Triche & C. Patrick Reynolds. (2007) Histone Deacetylase 1 Gene Expression and Sensitization of Multidrug-Resistant Neuroblastoma Cell Lines to Cytotoxic Agents by Depsipeptide. JNCI: Journal of the National Cancer Institute 99:14, pages 1107-1119.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.