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Ubiquitin Ligases in Cancer: Ushers for Degradation

, Ph.D. & , Ph.D.
Pages 502-513 | Published online: 11 Jun 2009

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Manikandan Lakshmanan, Usha Bughani, Senthil Duraisamy, Manish Diwan, Sunanda Dastidar & Abhijit Ray. (2008) Molecular targeting of E3 ligases – a therapeutic approach for cancer. Expert Opinion on Therapeutic Targets 12:7, pages 855-870.
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Jan Sterz, Ivana von Metzler, Jens-Claus Hahne, Britta Lamottke, Jessica Rademacher, Ulrike Heider, Evangelos Terpos & Orhan Sezer. (2008) The potential of proteasome inhibitors in cancer therapy. Expert Opinion on Investigational Drugs 17:6, pages 879-895.
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Articles from other publishers (13)

Qipeng Xie, Xiaohui Hua, Chao Huang, Xin Liao, Zhongxian Tian, Jiheng Xu, Yunping Zhao, Guosong Jiang, Haishan Huang & Chuanshu Huang. (2022) SOX2 Promotes Invasion in Human Bladder Cancers through MMP2 Upregulation and FOXO1 Downregulation. International Journal of Molecular Sciences 23:20, pages 12532.
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Ji-hong Cui & Xin Xie. (2017) UCH-L1 Expressed by Podocytes: a Potentially Therapeutic Target for Lupus Nephritis?. Inflammation 40:2, pages 657-665.
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John Silke & Domagoj Vucic. 2014. Regulated Cell Death Part B - Necroptotic, Autophagic and other Non-apoptotic Mechanisms. Regulated Cell Death Part B - Necroptotic, Autophagic and other Non-apoptotic Mechanisms 35 65 .
Sayed Mohammad Shafiee, Atefeh Seghatoleslam, Mohsen Nikseresht, Seyed Vahid Hosseini, Mahvash Alizadeh-Naeeni, Akbar Safaei & Ali Akbar Owji. (2013) UBE2Q1 expression in human colorectal tumors and cell lines. Molecular Biology Reports 40:12, pages 7045-7051.
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Jie Yin, Ji‐Min Zhu & Xi‐Zhong Shen. (2012) New insights into pre‐mRNA processing factor 19: A multi‐faceted protein in humans. Biology of the Cell 104:12, pages 695-705.
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Shweta Arya, Gaurav Sharma, Preeti Gupta & Swati Tiwari. (2012) In silico analysis of ubiquitin/ubiquitin-like modifiers and their conjugating enzymes in Entamoeba species. Parasitology Research 111:1, pages 37-51.
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Jennifer Hurst-Kennedy, Lih-Shen Chin & Lian Li. (2012) Ubiquitin C-Terminal Hydrolase L1 in Tumorigenesis. Biochemistry Research International 2012, pages 1-10.
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Noel Ferro & Thomas Bredow. (2009) Assessment of quantum‐chemical methods for electronic properties and geometry of signaling biomolecules. Journal of Computational Chemistry 31:5, pages 1063-1079.
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G Chen, Y Wang, M Garate, J Zhou & G Li. (2009) The tumor suppressor ING3 is degraded by SCFSkp2-mediated ubiquitin–proteasome system. Oncogene 29:10, pages 1498-1508.
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Kerry Routenberg Love, Renuka K. Pandya, Eric Spooner & Hidde L. Ploegh. (2009) Ubiquitin C-Terminal Electrophiles Are Activity-Based Probes for Identification and Mechanistic Study of Ubiquitin Conjugating Machinery. ACS Chemical Biology 4:4, pages 275-287.
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Cindy M. Quezada, Stuart W. Hicks, Jorge E. Galán & C. Erec Stebbins. (2009) A family of Salmonella virulence factors functions as a distinct class of autoregulated E3 ubiquitin ligases . Proceedings of the National Academy of Sciences 106:12, pages 4864-4869.
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John W. BlankenshipEugene VarfolomeevTatiana GoncharovAnna V. FedorovaDonald S. KirkpatrickAnita Izrael-TomasevicLilian PhuDavid ArnottMariam AghajanKerry ZobelJ. Fernando BazanWayne J. FairbrotherKurt DeshayesDomagoj Vucic. (2008) Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP2. Biochemical Journal 417:1, pages 149-165.
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Xiaoli Wang, Roger A. Herr & Ted Hansen. (2008) Viral and cellular MARCH ubiquitin ligases and cancer. Seminars in Cancer Biology 18:6, pages 441-450.
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