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ORIGINAL ARTICLECellular and Molecular Biology

OSM, LIF, Its Receptors, and Its Relationship with the Malignance in Human Breast Carcinoma (In Situ and in Infiltrative)

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Pages 222-229 | Published online: 11 Jun 2009

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Benjamin L. Bryson, Damian J. Junk, Rocky Cipriano & Mark W. Jackson. (2017) STAT3-mediated SMAD3 activation underlies Oncostatin M-induced Senescence. Cell Cycle 16:4, pages 319-334.
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Shili Xu & Nouri Neamati. (2013) gp130: a promising drug target for cancer therapy. Expert Opinion on Therapeutic Targets 17:11, pages 1303-1328.
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Natalie A. Sims & Rachelle W. Johnson. (2012) Leukemia inhibitory factor: A paracrine mediator of bone metabolism. Growth Factors 30:2, pages 76-87.
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Articles from other publishers (35)

Suryavathi Viswanadhapalli, Kalarickal V. Dileep, Kam Y.J. Zhang, Hareesh B. Nair & Ratna K. Vadlamudi. (2022) Targeting LIF/LIFR signaling in cancer. Genes & Diseases 9:4, pages 973-980.
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Carla M. Felcher, Emilia S. Bogni & Edith C. Kordon. (2022) IL-6 Cytokine Family: A Putative Target for Breast Cancer Prevention and Treatment. International Journal of Molecular Sciences 23:3, pages 1809.
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Megan M. Jorgensen & Pilar de la Puente. (2022) Leukemia Inhibitory Factor: An Important Cytokine in Pathologies and Cancer. Biomolecules 12:2, pages 217.
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Nazanin Vaziri, Laleh Shariati, Ali Zarrabi, Ali Farazmand & Shaghayegh Haghjooy Javanmard. (2021) Cancer-Associated Fibroblasts Regulate the Plasticity of Breast Cancer Stemness through the Production of Leukemia Inhibitory Factor. Life 11:12, pages 1298.
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Joe Christianson, Julia Thom Oxford & Cheryl L. Jorcyk. (2021) Emerging Perspectives on Leukemia Inhibitory Factor and its Receptor in Cancer. Frontiers in Oncology 11.
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Carlos Martínez-Pérez, Jess Leung, Charlene Kay, James Meehan, Mark Gray, J Michael Dixon & Arran K Turnbull. (2021) The Signal Transducer IL6ST (gp130) as a Predictive and Prognostic Biomarker in Breast Cancer. Journal of Personalized Medicine 11:7, pages 618.
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Benjamin L. Bryson, Ilaria Tamagno, Sarah E. Taylor, Neetha Parameswaran, Noah M. Chernosky, Nikhila Balasubramaniam & Mark W. Jackson. (2021) Aberrant Induction of a Mesenchymal/Stem Cell Program Engages Senescence in Normal Mammary Epithelial Cells. Molecular Cancer Research 19:4, pages 651-666.
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Nazanin Vaziri, Laleh Shariati & Shaghayegh Haghjooy Javanmard. (2020) Leukemia inhibitory factor: A main controller of breast cancer. Journal of Biosciences 45:1.
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Ziwei Han, Ruisen Zhan, Shijie Chen, Jia Deng, Jian Shi & Weiguo Wang. (2019) miR‐181b/Oncostatin m axis inhibits prostate cancer bone metastasis via modulating osteoclast differentiation. Journal of Cellular Biochemistry 121:2, pages 1664-1674.
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Jihua Shi, Xue Xu, Jun Du, Haimeng Cui & Qingfeng Luo. (2019) Expression of Oncostatin M in Early Gastric Cancer and Precancerous Lesions. Gastroenterology Research and Practice 2019, pages 1-7.
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Qiu-Xu Teng, Yunali V. Ashar, Pranav Gupta, Eddie Gadee, Ying-Fang Fan, Sandra E. Reznik, John N.D. Wurpel & Zhe-Sheng Chen. (2019) Revisiting mTOR inhibitors as anticancer agents. Drug Discovery Today 24:10, pages 2086-2095.
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Yu Shi, Sean Hunter & Tony Hunter. (2019) Stem Cell Factor LIFted as a Promising Clinical Target for Cancer Therapy. Molecular Cancer Therapeutics 18:8, pages 1337-1340.
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Ken Tawara, Hannah Scott, Jacqueline Emathinger, Alex Ide, Ryan Fox, Daniel Greiner, Dollie LaJoie, Danielle Hedeen, Madhuri Nandakumar, Andrew J. Oler, Ryan Holzer & Cheryl Jorcyk. (2019) Co-Expression of VEGF and IL-6 Family Cytokines is Associated with Decreased Survival in HER2 Negative Breast Cancer Patients: Subtype-Specific IL-6 Family Cytokine-Mediated VEGF Secretion. Translational Oncology 12:2, pages 245-255.
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Ken Tawara, Celeste Bolin, Jordan Koncinsky, Sujatha Kadaba, Hunter Covert, Caleb Sutherland, Laura Bond, Joseph Kronz, Joel R. Garbow & Cheryl L. Jorcyk. (2018) OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung. Breast Cancer Research 20:1.
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Srimoyee Mukherjee & Sumita Sengupta Bandyopadhyay. (2018) Mechanism of prostaglandin E2-induced transcriptional up-regulation of Oncostatin-M by CREB and Sp1. Biochemical Journal 475:2, pages 477-494.
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Sukru Gulluoglu, Mesut Sahin, Emre Can Tuysuz, Cumhur Kaan Yaltirik, Aysegul Kuskucu, Ferda Ozkan, Fikrettin Sahin, Ugur Ture & Omer Faruk Bayrak. (2017) Leukemia Inhibitory Factor Promotes Aggressiveness of Chordoma. Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 25:7, pages 1177-1188.
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Lapeire Lore, Hendrix An, Lecoutere Evelyne, Van Bockstal Mieke, Vandesompele Jo, Maynard Dawn, Braems Geert, Van Den Broecke Rudy, Müller Cathérine, Bracke Marc, Cocquyt Véronique, Denys Hannelore & De Wever Olivier. (2017) Secretome analysis of breast cancer-associated adipose tissue to identify paracrine regulators of breast cancer growth. Oncotarget 8:29, pages 47239-47249.
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Sanya-Eduarda Kuzet & Cedric Gaggioli. (2016) Fibroblast activation in cancer: when seed fertilizes soil. Cell and Tissue Research 365:3, pages 607-619.
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Jureeporn Chuerduangphui, Chamsai Pientong, Ponlatham Chaiyarit, Natcha Patarapadungkit, Apinya Chotiyano, Bunkerd Kongyingyoes, Supannee Promthet, Piyawut Swangphon, Weerayut Wongjampa & Tipaya Ekalaksananan. (2016) Effect of human papillomavirus 16 oncoproteins on oncostatin M upregulation in oral squamous cell carcinoma. Medical Oncology 33:8.
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June-Hong Kim, Eun-Hyo Cho & Tae-Won Jeon. (2016) The Effects of Long-term Exercise on the Expression of SPARC and OSM in Colon Cancer-induced Mice. Exercise Science 25:2, pages 76-84.
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Mary Doherty, Jacob Smigiel, Damian Junk & Mark Jackson. (2016) Cancer Stem Cell Plasticity Drives Therapeutic Resistance. Cancers 8:12, pages 8.
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Wittaya Chaiwangyen, Stephanie Ospina-Prieto, Diana M. Morales-Prieto, Francisco Lazaro Pereira de Sousa, Jana Pastuschek, Justine S. Fitzgerald, Ekkehard Schleussner & Udo R. Markert. (2016) Oncostatin M and leukaemia inhibitory factor trigger signal transducer and activator of transcription 3 and extracellular signal-regulated kinase 1/2 pathways but result in heterogeneous cellular responses in trophoblast cells. Reproduction, Fertility and Development 28:5, pages 608.
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Bin Liu, Yi Lu, Jinzhi Li, Yanping Liu, Jian Liu & Weiguo Wang. (2015) Leukemia inhibitory factor promotes tumor growth and metastasis in human osteosarcoma via activating STAT3. APMIS 123:10, pages 837-846.
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Jill I Murray, Nathan R West, Leigh C Murphy & Peter H Watson. (2015) Intratumoural inflammation and endocrine resistance in breast cancer. Endocrine-Related Cancer 22:1, pages R51-R67.
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Luguo Sun, Liyan Sui, Xianling Cong, Kejuan Ma, Xiaobo Ma, Yanxin Huang, Cong Fan, Xueqi Fu & Kewei Ma. (2014) Low incidence of IL6ST (gp130) mutations in exon 6 in lung cancer of a Chinese cohort. Cancer Genetics 207:7-8, pages 291-298.
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Jean Albrengues, Isabelle Bourget, Catherine Pons, Vincent Butet, Paul Hofman, Sophie Tartare-Deckert, Chloe C. Feral, Guerrino Meneguzzi & Cedric Gaggioli. (2014) LIF Mediates Proinvasive Activation of Stromal Fibroblasts in Cancer. Cell Reports 7:5, pages 1664-1678.
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Damian Junk, Benjamin Bryson & Mark Jackson. (2014) HiJAK’d Signaling; the STAT3 Paradox in Senescence and Cancer Progression. Cancers 6:2, pages 741-755.
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Xiaoyan Li, Qifeng Yang, Haiyang Yu, Lihua Wu, Yuhan Zhao, Cen Zhang, Xuetian Yue, Zhen Liu, Hao Wu, Bruce G. Haffty, Zhaohui Feng & Wenwei Hu. (2014) LIF promotes tumorigenesis and metastasis of breast cancer through the AKT-mTOR pathway. Oncotarget 5:3, pages 788-801.
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Koji Taniguchi & Michael Karin. (2014) IL-6 and related cytokines as the critical lynchpins between inflammation and cancer. Seminars in Immunology 26:1, pages 54-74.
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Carl D. Richards. (2013) The Enigmatic Cytokine Oncostatin M and Roles in Disease. ISRN Inflammation 2013, pages 1-23.
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N. R. West, L. C. Murphy & P. H. Watson. (2012) Oncostatin M suppresses oestrogen receptor-  expression and is associated with poor outcome in human breast cancer. Endocrine Related Cancer 19:2, pages 181-195.
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Pernille Hojman, Christine Dethlefsen, Claus Brandt, Jakob Hansen, Line Pedersen & Bente Klarlund Pedersen. (2011) Exercise-induced muscle-derived cytokines inhibit mammary cancer cell growth. American Journal of Physiology-Endocrinology and Metabolism 301:3, pages E504-E510.
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Tasneem Kausar, Rinu Sharma, Md. Raghibul Hasan, Anoop Saraya, Tushar K. Chattopadhyay, Siddartha Datta Gupta & Ranju Ralhan. (2011) Overexpression of a splice variant of oncostatin M receptor beta in human esophageal squamous carcinoma. Cellular Oncology 34:3, pages 177-187.
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Jung Eun Shin, Su Hyung Park & Yeun Kyu Jang. (2010) Epigenetic up-regulation of leukemia inhibitory factor (LIF) gene during the progression to breast cancer. Molecules and Cells 31:2, pages 181-189.
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Carolina Schere Levy, Victoria Slomiansky, Albana Gattelli, Karen Nahmod, Federico Pelisch, Matias Blaustein, Anabella Srebrow, Omar A. Coso & Edith C. Kordon. (2010) Tumor necrosis factor alpha induces LIF expression through ERK1/2 activation in mammary epithelial cells. Journal of Cellular Biochemistry 110:4, pages 857-865.
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