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Cancer Investigation Volume 35, 2017 - Issue 9
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Article

Divergent Anticancer Activity of Free and Formulated Camel Milk α-Lactalbumin

Vladimir N. UverskyDepartment of Biological Sciences, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia;Institute for Biological Instrumentation of the Russian Academy of Sciences, Pushchino, Moscow region, Russia;Department of Molecular Medicine and USF Health Byrd Alzheimer's Research Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, USAORCID Iconhttp://orcid.org/0000-0002-4037-5857
ORCID Icon,
Esmail M. El-FakharanyTherapeutic and Protective Proteins Laboratory, Protein Research Department, Medical Biotechnology Department, Genetic Engineering and Biotechnology Research Institute, City for Scientific Research and Technology Applications (SRTA-City), Alexandria, EgyptORCID Iconhttp://orcid.org/0000-0001-8246-0075
ORCID Icon,
Marwa M. Abu-SerieMedical Biotechnology Department, Genetic Engineering and Biotechnology Research Institute, City for Scientific Research and Technology Applications (SRTA-City), Alexandria, Egypt
,
Hussein A. AlmehdarDepartment of Biological Sciences, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
&
Elrashdy M. RedwanDepartment of Biological Sciences, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia;Therapeutic and Protective Proteins Laboratory, Protein Research Department, Medical Biotechnology Department, Genetic Engineering and Biotechnology Research Institute, City for Scientific Research and Technology Applications (SRTA-City), Alexandria, EgyptCorrespondence[email protected] [email protected]
Pages 610-623 | Received 03 Jan 2017, Accepted 27 Aug 2017, Published online: 26 Sep 2017

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Muhammad Asif Arain, Gul Bahar Khaskheli, Atta Hussain Shah, Illahi Bakhash Marghazani, Ghulam Shabir Barham, Qurban Ali Shah, Faiz Muhammad Khand, Jameel Ahmed Buzdar, Feroza Soomro & Sarfraz Ali Fazlani. (2023) Nutritional significance and promising therapeutic/medicinal application of camel milk as a functional food in human and animals: a comprehensive review. Animal Biotechnology 34:6, pages 1988-2005.
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Esmail M. El-Fakharany, Hamada El‑Gendi, Khaled Abdel-Wahhab, Marwa M. Abu-Serie, Doaa Galal El-Sahra & Mahmoud Ashry. (2023) Therapeutic efficacy of α-lactalbumin coated oleic acid based liposomes against colorectal carcinoma in Caco-2 cells and DMH-treated albino rats. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-15.
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M. Selva Muthukumaran, Priti Mudgil, Waqas N Baba, Mohammed Akli Ayoub & Sajid Maqsood. (2023) A comprehensive review on health benefits, nutritional composition and processed products of camel milk. Food Reviews International 39:6, pages 3080-3116.
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Esmail M. El-Fakharany, Mahmoud Ashry, Marwa M. Abu‑Serie, Khaled G. Abdel-Wahhab, Doaa Galal El-Sahra & Hamada El‑Gendi. (2023) In Vitro and In Vivo Synergistic Antitumor Activity of Albumin-Coated Oleic Acid-Loaded Liposomes toward Hepatocellular Carcinoma. Cancer Investigation 41:7, pages 621-639.
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Esmail El-Fakharany, Hanaa Orabi, Eman Abdelkhalek & Nagwa Sidkey. (2022) Purification and biotechnological applications of L-asparaginase from newly isolated Bacillus halotolerans OHEM18 as antitumor and antioxidant agent. Journal of Biomolecular Structure and Dynamics 40:9, pages 3837-3849.
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Leonid Breydo, Hussein A. Almehdar, Esmail M. El-Fakharany, Elrashdy M. Redwan & Vladimir N. Uversky. (2018) Not all AMLETs are made equal: complexes of cow and camel α-lactalbumin with oleic acid show different structure and stability. Journal of Biomolecular Structure and Dynamics 36:16, pages 4405-4412.
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Roua Lajnaf, Sawsan Feki, Salma Ben Ameur, Hamadi Attia, Thouraya Kammoun, Mohamed Ali Ayadi & Hatem Masmoudi. (2023) Cow's milk alternatives for children with cow's milk protein allergy - Review of health benefits and risks of allergic reaction. International Dairy Journal 141, pages 105624.
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Chen Liu, Ling-Xiao Liu, Jie Yang & Yun-Guo Liu. (2023) Exploration and analysis of the composition and mechanism of efficacy of camel milk. Food Bioscience 53, pages 102564.
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Hussein A. Almehdar, Nawal Abd El-Baky, Ehab H. Mattar, Raed Albiheyri, Atif Bamagoos, Abdullah Aljaddawi, Vladimir N. Uversky & Elrashdy M. Redwan. (2023) Exploring the mechanisms by which camel lactoferrin can kill Salmonella enterica serovar typhimurium and Shigella sonnei . PeerJ 11, pages e14809.
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Ahmed K. Saleh, Hamada El-Gendi, Esmail M. El-Fakharany, Medhat E. Owda, Mohamed A. Awad & Elbadawy A. Kamoun. (2022) Exploitation of cantaloupe peels for bacterial cellulose production and functionalization with green synthesized Copper oxide nanoparticles for diverse biological applications. Scientific Reports 12:1.
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Esmail M. El-Fakharany, Mahmoud Ashry, Abd-Elaleem H. Abd-Elaleem, Mahmoud H. Romeih, Fatma Adly Morsy, Reem A. Shaban & Khaled G. Abdel-Wahhab. (2022) Therapeutic efficacy of Nano-formulation of lactoperoxidase and lactoferrin via promoting immunomodulatory and apoptotic effects. International Journal of Biological Macromolecules 220, pages 43-55.
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Hosam M. Habib, Esmail M. El-Fakharany, E. Kheadr & Wissam H. Ibrahim. (2022) Grape seed proanthocyanidin extract inhibits DNA and protein damage and labile iron, enzyme, and cancer cell activities. Scientific Reports 12:1.
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Davuddin Baig, Latha Sabikhi, Yogesh Khetra & Prashant Ashok Shelke. (2022) Technological challenges in production of camel milk cheese and ways to overcome them – A review. International Dairy Journal 129, pages 105344.
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Eman E. Elsharkawy, Neveen A. El-Nisr, Nahed M. Wahba & Walaa M. Elsherif. (2021) Hepatotoxicity of methoxychlor and camel milk restoration. Nutrition & Food Science 52:3, pages 483-496.
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Thao M. Ho & Nidhi Bansal. 2022. Encyclopedia of Dairy Sciences. Encyclopedia of Dairy Sciences 854 859 .
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Ehab H. Mattar, Fatma Elrashdy, Hussein A. Almehdar, Vladimir N. Uversky & Elrashdy M. Redwan. (2021) Natural resources to control COVID-19: could lactoferrin amend SARS-CoV-2 infectivity?. PeerJ 9, pages e11303.
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Esmail M. El-Fakharany, Mabroka H. Saad, Marwa S. Salem & Nagwa M. Sidkey. (2020) Biochemical characterization and application of a novel lectin from the cyanobacterium Lyngabya confervoides MK012409 as an antiviral and anticancer agent. International Journal of Biological Macromolecules 161, pages 417-430.
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Changwan Cui, Yiping Lu, Yuanyi Yue, Si Wu, Shuang Wang, Miao Yu & Zhengrong Sun. (2020) Camel milk regulates T‐cell proliferation to alleviate dextran sodium sulphate‐induced colitis in mice. International Journal of Food Science & Technology 55:4, pages 1648-1660.
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Mo'ez Al-Islam Ezzat Faris & Hadeel Ghazzawi. 2020. Handbook of Research on Health and Environmental Benefits of Camel Products. Handbook of Research on Health and Environmental Benefits of Camel Products 155 184 .
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