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Original Articles

Modeling of a Possible Conformational Change Associated With the Catalytic Mechanism in the Hammerhead Ribozyme

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Pages 515-522 | Received 28 Sep 1995, Published online: 21 May 2012

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RajendraP. Ojha, MadanM. Dhingra, MuktiH. Sarma, YashP. Myer, RobertF. Setlik, Masayuki Shibata, A. Latif. Kazim, RickL. Ornstein, Robert Rein, ChristopherJ. Turner & RamaswamyH. Sarma. (1997) Structure of an Anti-HIV-1 Hammerhead Ribozyme Complex with a 17-mer DNA Substrate Analog of HIV-1 gag RNA and a Mechanism for the Cleavage Reaction: 750 MHz NMR and Computer Experiments. Journal of Biomolecular Structure and Dynamics 15:2, pages 185-215.
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Articles from other publishers (8)

Yeon Jae Ko, Piotr Storoniak, Haopeng Wang, Kit H. Bowen & Janusz Rak. (2012) Photoelectron spectroscopy and density functional theory studies on the uridine homodimer radical anions. The Journal of Chemical Physics 137:20.
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Lisa Scherer & John J. Rossi. 2005. Cancer Gene Therapy. Cancer Gene Therapy 51 63 .
John J. Rossi. 2004. Nucleic Acid Therapeutics in Cancer. Nucleic Acid Therapeutics in Cancer 45 64 .
Rhonda A. Torres, Fahmi Himo, Thomas C. Bruice, Louis Noodleman & Timothy Lovell. (2003) Theoretical Examination of Mg 2+ -Mediated Hydrolysis of a Phosphodiester Linkage as Proposed for the Hammerhead Ribozyme . Journal of the American Chemical Society 125:32, pages 9861-9867.
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Rhonda A. Torres & Thomas C. Bruice. (2000) The Mechanism of Phosphodiester Hydrolysis:  Near In-line Attack Conformations in the Hammerhead Ribozyme. Journal of the American Chemical Society 122:5, pages 781-791.
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Nicolas Leulliot, Mahmoud Ghomi, Giovanni Scalmani & Gaston Berthier. (1999) Ground State Properties of the Nucleic Acid Constituents Studied by Density Functional Calculations. I. Conformational Features of Ribose, Dimethyl Phosphate, Uridine, Cytidine, 5‘-Methyl Phosphate−Uridine, and 3‘-Methyl Phosphate−Uridine. The Journal of Physical Chemistry A 103:43, pages 8716-8724.
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Jean-Pierre Simorre, Pascale Legault, Narayan Baidya, Olke C. Uhlenbeck, Lara Maloney, Francine Wincott, Nassim Usman, Leonid Beigelman & Arthur Pardi. (1998) Structural Variation Induced by Different Nucleotides at the Cleavage Site of the Hammerhead Ribozyme. Biochemistry 37:12, pages 4034-4044.
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Narayan Baidya & Olke C. Uhlenbeck. (1997) A Kinetic and Thermodynamic Analysis of Cleavage Site Mutations in the Hammerhead Ribozyme. Biochemistry 36:5, pages 1108-1114.
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