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Original Articles

NMR Investigation of the Complexation of Daunomycin with Deoxytetranucleotides of Different Base Sequence in Aqueous Solution

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Pages 887-901 | Received 16 Dec 1999, Published online: 15 May 2012

Keep up to date with the latest research on this topic with citation updates for this article.

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Giampaolo Barone, Célia Fonseca Guerra, Noemi Gambino, Arturo Silvestri, Antonino Lauria, Anna Maria Almerico & F. Matthias Bickelhaupt. (2008) Intercalation of Daunomycin into Stacked DNA Base Pairs. DFT Study of an Anticancer Drug. Journal of Biomolecular Structure and Dynamics 26:1, pages 115-129.
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D.V. Ovchinnikov, S.F. Baranovsky, A.O. Rozvadovska, O.V. Rogova, K.A. Veselkov, D.V. Ermolaev, H. Parkes, D.B. Davies & M.P. Evstigneev. (2007) Structural Basis for the Binding Affinity of a Homologous Series of Synthetic Phenoxazone Drugs with DNA: NMR and Molecular Mechanics Analysis. Journal of Biomolecular Structure and Dynamics 24:5, pages 443-453.
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Dennis A. Veselkov, Leonid Karawajew, Alexei N. Veselkov & David B. Davies . (2004) 1H NMR investigation of the hetero-association of phenanthridine dyes with Daunomycin: effect of substitution of amino with azido groups in the dye chromophore. Molecular Physics 102:18, pages 1933-1942.
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Michael Trieb, Christine Rauch, Bernd Wellenzohn, Fajar Wibowo, Thomas Loerting, Erwin Mayer & KlausR. Liedl. (2004) Daunomycin Intercalation Stabilizes Distinct Backbone Conformations of DNA. Journal of Biomolecular Structure and Dynamics 21:5, pages 713-724.
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DAVIDB. DAVIES, DENNISA. VESELKOV, VENIAMINV. KODINTSEV, MAXIMP. EVSTIGNEEV & ALEXEIN. VESELKOV. (2000) 1H NMR investigation of the hetero-association of aromatic molecules in aqueous solution: factors involved in the stabilization of complexes of daunomycin and acridine drugs. Molecular Physics 98:23, pages 1961-1971.
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Sayantan Bhaduri, Nihar Ranjan & Dev P Arya. (2018) An overview of recent advances in duplex DNA recognition by small molecules. Beilstein Journal of Organic Chemistry 14, pages 1051-1086.
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Maolin Wang, Yuanyuan Yu, Chao Liang, Aiping Lu & Ge Zhang. (2016) Recent Advances in Developing Small Molecules Targeting Nucleic Acid. International Journal of Molecular Sciences 17:6, pages 779.
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Benjamin Doughty, Yi Rao, Samuel W. Kazer, Sheldon J. J. Kwok, Nicholas J. Turro & Kenneth B. Eisenthal. (2013) Binding of the Anti-Cancer Drug Daunomycin to DNA Probed by Second Harmonic Generation. The Journal of Physical Chemistry B 117:49, pages 15285-15289.
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Jia Sheng, Jianhua Gan & Zhen Huang. (2013) Structure-Based DNA-Targeting Strategies with Small Molecule Ligands for Drug Discovery. Medicinal Research Reviews 33:5, pages 1119-1173.
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Matthieu Wilhelm, Arnab Mukherjee, Benjamin Bouvier, Krystyna Zakrzewska, James T. Hynes & Richard Lavery. (2012) Multistep Drug Intercalation: Molecular Dynamics and Free Energy Studies of the Binding of Daunomycin to DNA. Journal of the American Chemical Society 134:20, pages 8588-8596.
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Edward R. Zartler & Gary E. Martin. (2011) The use of 1H–31P GHMBC and covariance NMR to unambiguously determine phosphate ester linkages in complex polysaccharide mixtures. Journal of Biomolecular NMR 51:3, pages 357-367.
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Pamita Awasthi, Shilpa Dogra, Lalit K. Awasthi & Ritu Barthwal. 2011. Software Tools and Algorithms for Biological Systems. Software Tools and Algorithms for Biological Systems 385 400 .
A. A. Hernandez Santiago, D. D. Andrejuk, A. M. Cervantes Tavera, D. B. Davies & M. P. Evstigneev. (2009) Complexation of Biologically Active Aromatic Compounds with DNA in the Presence of Theophylline. Journal of Biological Physics 35:2, pages 115-126.
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Prashansa Agrawal, Sudhir Kumar Barthwal, Girjesh Govil & Ritu Barthwal. (2009) Solution studies on the complex of 4′-epiadriamycin-d-(CGATCG)2 followed by time-resolved fluorescence measurement, diffusion ordered spectroscopy and restrained molecular dynamics simulations. Bioorganic & Medicinal Chemistry 17:7, pages 2793-2811.
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Kazuo Nakamoto, Masamichi Tsuboi & Gary D. Strahan. 2008. Drug–DNA Interactions. Drug–DNA Interactions 119 208 .
Claudia Bonechi, Silvia Martini, Agnese Magnani & Claudio Rossi. (2008) Stacking interaction study of trans ‐resveratrol ( trans ‐3,5,4′‐trihydroxystilbene) in solution by Nuclear Magnetic Resonance and Fourier Transform Infrared Spectroscopy . Magnetic Resonance in Chemistry 46:7, pages 625-629.
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M. P. Evstigneev, D. A. Beshnova & A. O. Rozvadovskaya. (2008) A “microscopic” model of complexation between intercalators and DNA: Analysis of NMR spectroscopy data. Biophysics 53:1, pages 38-43.
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M.P. Evstigneev, A.O. Lantushenko, V.P. Evstigneev, Yu. V. Mykhina & D.B. Davies. (2008) Quantitation of the molecular mechanisms of biological synergism in a mixture of DNA-acting aromatic drugs. Biophysical Chemistry 132:2-3, pages 148-158.
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V.V. Kostjukov, V.I. Pahomov, D.D. Andrejuk, D.B. Davies & M.P. Evstigneev. (2007) Investigation of the complexation of the anti-cancer drug novantrone with the hairpin structure of the deoxyheptanucleotide 5′-d(GpCpGpApApGpC). Journal of Molecular Structure 843:1-3, pages 78-86.
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V.V. Kostjukov, A.O. Lantushenko, D.B. Davies & M.P. Evstigneev. (2007) On the origin of the decrease in stability of the DNA hairpin d(GCGAAGC) on complexation with aromatic drugs. Biophysical Chemistry 129:1, pages 56-59.
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M. P. Evstigneev, V. V. Khomich & D. B. Davies. (2006) Complexation of anthracycline drugs with DNA in the presence of caffeine. European Biophysics Journal 36:1, pages 1-11.
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M. P. Evstigneev, S. F. Baranovsky, K. A. Rybakova & D. B. Davies. (2006) Complexation of the quinolone antibiotic norfloxacin with DNA. Molecular Biology 40:5, pages 805-810.
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V. V. Kostjukov, V. I. Pahomov & L. N. Dimant. (2006) Structural characteristics of intercalation complex of deoxyheptanucleotide hairpin d(GCGAAGC) with anthracycline antibiotic daunomycin. Biopolymers and Cell 22:5, pages 339-349.
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M.P. Evstigneev, K.A. Rybakova & D.B. Davies. (2006) Complexation of norfloxacin with DNA in the presence of caffeine. Biophysical Chemistry 121:2, pages 84-95.
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A. O. Rozvadovskaya, V. P. Evstigneev, D. B. Davies & M. P. Evstigneev. (2006) Interaction between aromatic antibiotics and vitamins: 1H NMR study of heteroassociation of nicotinamide and anthracycline antitumor antibiotics. Biophysics 51:2, pages 176-185.
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M.P. Evstigneev, Yu.V. Mykhina & D.B. Davies. (2005) Complexation of daunomycin with a DNA oligomer in the presence of an aromatic vitamin (B2) determined by NMR spectroscopy. Biophysical Chemistry 118:2-3, pages 118-127.
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D.B. Davies, M.P. Evstigneev, D.A. Veselkov & A.N. Veselkov. (2005) Hetero-association of anticancer antibiotics in aqueous solution: NMR and molecular mechanics analysis. Biophysical Chemistry 117:2, pages 111-118.
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M.P. Evstigneev, A.O. Rozvadovskaya, O.V. Zubchenok, Yu.V. Mukhina, D.B. Davies & A.N. Veselkov. (2005) Analysis by Means of 1H NMR Spectroscopy of Heteroassociaion in Water Solution of Antitumor Antibiotics Daunomycin and Actinomycin D. Russian Journal of Organic Chemistry 41:8, pages 1158-1164.
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Monica Jain, Sudhir Kumar Barthwal, Ritu Barthwal & Girjesh Govil. (2005) Restrained molecular dynamics studies on complex of adriamycin with DNA hexamer sequence d-CGATCG. Archives of Biochemistry and Biophysics 439:1, pages 12-24.
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M. P. Evstigneev, A. O. Rozvadovskaya, A. S. Chubarov, A. A. Hernandez Santiago, D. B. Davies & A. N. Veselkov. (2005) Structural and thermodynamic analysis of heteroassociation of daunomycin and flavin mononucleotide molecules in water by 1H NMR spectroscopy. Journal of Structural Chemistry 46:1, pages 67-74.
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A. N. Veselkov, R. J. Eaton, V. I. Pahomov, O. V. Rogova, V. S. Volynkin, A. V. Semanin, L. N. Djimant & D. B. Davies. (2004) Distinctive features of the self-association of deoxyhexanucleotide 5'-d(GpCpApTpGpC) and its complexation with anthracycline antibiotic daunomycin in aqueous solution. Biopolymers and Cell 20:6, pages 479-492.
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A.N Veselkov, M.P Evstigneev, A.O Rozvadovskaya, A Hernandez Santiago, O.V Zubchenok, L.N Djimant & D.B Davies. (2004) 1H NMR structural and thermodynamical analysis of the hetero-association of daunomycin and novatrone in aqueous solution. Journal of Molecular Structure 701:1-3, pages 31-37.
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A.N. Veselkov, M.P. Evstigneev, D.A. Veselkov, A.A. Hernandez Santiago & D.B. Davies. (2004) 1H NMR investigation of the self-association of ethidium homodimer and its complexation with propidium iodide in aqueous solution. Journal of Molecular Structure 690:1-3, pages 17-24.
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A. N. Veselkov, R. J. Eaton, A. O. Lantushenko, O. V. Rogova, A. Hernandez Santiago & D. B. Davies. (2003) 2D 1H-NMR analysis of complexation of phenoxazone compound actinocyl-bis-(2-dimethylaminoethyl) amide with deoxytetranucleotide 5'-d(TpGpCpA) in aqueous solution. Biopolymers and Cell 19:6, pages 504-512.
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A. N. Veselkov, S. A. Vysotsky, M. P. Evstigneev, D. A. Veselkov, L. N. Djimant, P. A. Bolotin & D. B. Davies. (2002) 1H-NMR analysis of the interaction of antibiotic mitoxantrone with DNA in the presence of caffeine in aqueous solution. Biopolymers and Cell 18:4, pages 287-296.
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Giulietta Smulevich, Anna R. Mantini, Alessandro Feis & Mario P. Marzocchi. (2001) Resonance Raman spectra and transform analysis of anthracyclines and their complexes with DNA. Journal of Raman Spectroscopy 32:6-7, pages 565-578.
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