Advanced search
Publication Cover
Journal of Biomolecular Structure and Dynamics Volume 20, 2002 - Issue 1
Journal homepage
65
Views
24
CrossRef citations to date
0
Altmetric
Original Articles

The 1H-NMR Solution Structure of the Antitryptic Core Peptide of Bowman-Birk Inhibitor Proteins: A Minimal ‘Canonical Loop’

Arnd B.E. Brauer Departments of Chemistry, Imperial College of Science Technology and Medicine South Kensington, London, SW7 2AY, U.K.; Departments of Biological Sciences, Imperial College of Science Technology and Medicine South Kensington, London, SW7 2AY, U.K.
,
Geoff Kelly Departments of Biological Sciences, Imperial College of Science Technology and Medicine South Kensington, London, SW7 2AY, U.K.
,
Stephen J. Matthews Departments of Biological Sciences, Imperial College of Science Technology and Medicine South Kensington, London, SW7 2AY, U.K.
&
Robin J. Leatherbarrow Departments of Chemistry, Imperial College of Science Technology and Medicine South Kensington, London, SW7 2AY, U.K.
Pages 59-70 | Received 24 Jan 2002, Published online: 15 May 2012

Citations (24)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Arnd B.E. Brauer, Marco Nievo, JeffreyD. McBride & RobinJ. Leatherbarrow. (2003) The Structural Basis of a Conserved P2 Threonine in Canonical Serine Proteinase Inhibitors. Journal of Biomolecular Structure and Dynamics 20:5, pages 645-655.
Read now

Articles from other publishers (23)

Oleg Babii, Sergii Afonin, Christian Diel, Marcel Huhn, Jennifer Dommermuth, Tim Schober, Serhii Koniev, Andrii Hrebonkin, Alexander Nesterov‐Mueller, Igor V. Komarov & Anne S. Ulrich. (2021) Diarylethene‐Based Photoswitchable Inhibitors of Serine Proteases. Angewandte Chemie International Edition 60:40, pages 21789-21794.
Crossref
Oleg Babii, Sergii Afonin, Christian Diel, Marcel Huhn, Jennifer Dommermuth, Tim Schober, Serhii Koniev, Andrii Hrebonkin, Alexander Nesterov‐Mueller, Igor V. Komarov & Anne S. Ulrich. (2021) Diarylethen‐basierte lichtschaltbare Inhibitoren von Serinproteasen. Angewandte Chemie 133:40, pages 21958-21964.
Crossref
Agata Gitlin-Domagalska, Aleksandra Maciejewska & Dawid Dębowski. (2020) Bowman-Birk Inhibitors: Insights into Family of Multifunctional Proteins and Peptides with Potential Therapeutical Applications. Pharmaceuticals 13:12, pages 421.
Crossref
James A. Reihill, Xuan Ouyang, Zhixuan Yang, Lisa E. J. Douglas, Mei Zhou, Tianbao Chen & S. Lorraine Martin. (2020) A Novel Serine Protease Inhibitor PE-BBI Ameliorates Cockroach Extract-Mediated Airway Epithelial Barrier Dysfunction. Biomolecules 10:4, pages 515.
Crossref
Peng Lyu, Lilin Ge, Rui Ma, Ran Wei, Cian M. McCrudden, Tianbao Chen, Chris Shaw & Hang Fai Kwok. (2018) Identification and pharmaceutical evaluation of novel frog skin-derived serine proteinase inhibitor peptide–PE-BBI (Pelophylax esculentus Bowman-Birk inhibitor) for the potential treatment of cancer. Scientific Reports 8:1.
Crossref
B. Franke, J. S. Mylne & K. J. Rosengren. (2018) Buried treasure: biosynthesis, structures and applications of cyclic peptides hidden in seed storage albumins. Natural Product Reports 35:2, pages 137-146.
Crossref
Yan Lin, Haiying Hang, Tianbao Chen, Mei Zhou, Lei Wang & Chris Shaw. (2016) pLR-HL: A Novel Amphibian Bowman-Birk-type Trypsin Inhibitor from the Skin Secretion of the Broad-folded Frog, Hylarana latouchii . Chemical Biology & Drug Design 87:1, pages 91-100.
Crossref
Vera A. Korneeva, Mikhail M. Trubetskov, Alena V. Korshunova, Sofya V. Lushchekina, Vladimir N. Kolyadko, Olga V. Sergienko, Vladimir G. Lunin, Mikhail A. Panteleev & Fazoil I. Ataullakhanov. (2014) Interactions Outside the Proteinase-binding Loop Contribute Significantly to the Inhibition of Activated Coagulation Factor XII by Its Canonical Inhibitor from Corn. Journal of Biological Chemistry 289:20, pages 14109-14120.
Crossref
Sandra Cerqueira Barros, Ricardo O. Louro, Nuno M. Micaêlo, José Alberto Martins, João Carlos Marcos & Artur Cavaco-Paulo. (2013) NMR and molecular modelling studies on elastase inhibitor-peptides for wound management. Reactive and Functional Polymers 73:10, pages 1357-1365.
Crossref
C. V. S. Siva Prasad, Saurabh Gupta, Alex Gaponenko & Murlidhar Tiwari. (2013) Molecular Dynamic and Docking Interaction Study of Heterodera glycines Serine Proteinase with Vigna mungo Proteinase Inhibitor. Applied Biochemistry and Biotechnology 170:8, pages 1996-2008.
Crossref
Regine García Boy, Walter Mier, Eva Maria Nothelfer, Annette Altmann, Michael Eisenhut, Harald Kolmar, Michael Tomaszowski, Susanne Krämer & Uwe Haberkorn. (2009) Sunflower Trypsin Inhibitor 1 Derivatives as Molecular Scaffolds for the Development of Novel Peptidic Radiopharmaceuticals. Molecular Imaging and Biology 12:4, pages 377-385.
Crossref
Lucia Lioi, Incoronata Galasso, Maria Gloria Daminati & Angela Rosa Piergiovanni. (2009) Inhibitory properties and binding loop polymorphism in Bowman-Birk inhibitors from Phaseolus species. Genetic Resources and Crop Evolution 57:4, pages 533-542.
Crossref
Sophia N Yaliraki & Mauricio Barahona. (2007) Chemistry across scales: from molecules to cells. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 365:1861, pages 2921-2934.
Crossref
Arnd B.E. Brauer, Jeffrey D. McBride, Geoff Kelly, Stephen J. Matthews & Robin J. Leatherbarrow. (2007) Resisting degradation by human elastase: Commonality of design features shared by ‘canonical’ plant and bacterial macrocyclic protease inhibitor scaffolds. Bioorganic & Medicinal Chemistry 15:13, pages 4618-4628.
Crossref
Péter Hudáky & András Perczel. (2007) p K a optimized catalysis in serine proteinases, an ab initio study on the catalaytic His . International Journal of Quantum Chemistry 107:11, pages 2178-2183.
Crossref
Joao R. Costa & Sophia N. Yaliraki. (2006) Role of Rigidity on the Activity of Proteinase Inhibitors and Their Peptide Mimics. The Journal of Physical Chemistry B 110:38, pages 18981-18988.
Crossref
Péter Hudáky & András Perczel. (2005) A self-stabilized model of the chymotrypsin catalytic pocket. The energy profile of the overall catalytic cycle. Proteins: Structure, Function, and Bioinformatics 62:3, pages 749-759.
Crossref
Agnès M. Jaulent, Arnd B. E. Brauer, Stephen J. Matthews & Robin J. Leatherbarrow. (2005) Solution Structure of a Novel C2-Symmetrical Bifunctional Bicyclic Inhibitor Based on SFTI-1. Journal of Biomolecular NMR 33:1, pages 57-62.
Crossref
M. Taniguchi, K. Kamei, K. Kanaori, T. Koyama, T. Yasui, R. Takano, S. Harada, K. Tajima, C. Imada & S. Hara. (2005) Relationship between temporary inhibition and structure of disulfide-linkage analogs of marinostatin, a natural ester-linked protein protease inhibitor. Journal of Peptide Research 66:2, pages 49-58.
Crossref
Michael L. J. Korsinczky, Richard J. Clark & David J. Craik. (2005) Disulfide Bond Mutagenesis and the Structure and Function of the Head-to-Tail Macrocyclic Trypsin Inhibitor SFTI-1 , . Biochemistry 44:4, pages 1145-1153.
Crossref
Angela R. Piergiovanni & Incoronata Galasso. (2004) Polymorphism of trypsin and chymotrypsin binding loops in Bowman-Birk inhibitors from common bean (Phaseolus vulgaris L.). Plant Science 166:6, pages 1525-1531.
Crossref
Arnd B.E. Brauer & Robin J. Leatherbarrow. (2003) The conserved P1′ Ser of Bowman–Birk-type proteinase inhibitors is not essential for the integrity of the reactive site loop. Biochemical and Biophysical Research Communications 308:2, pages 300-305.
Crossref
Jeffrey D. McBride, Emma M. Watson, Arnd B. E. Brauer, Agnès M. Jaulent & Robin J. Leatherbarrow. (2004) Peptide mimics of the Bowman–Birk inhibitor reactive site loop. Peptide Science 66:2, pages 79-92.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.