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Journal of Biomolecular Structure and Dynamics Volume 34, 2016 - Issue 1
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Articles

Deciphering the impact of somatic mutations in exon 20 and exon 9 of PIK3CA gene in breast tumors among Indian women through molecular dynamics approach

N. SudhakarDepartment of Biotechnology, Dr. M.G.R. Educational and Research Institute (University), Maduravoyal, Chennai600 095, IndiaCorrespondence[email protected]
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,
C. George Priya DossMedical Biotechnology Division, School of Biosciences and Technology (SBST), VIT University, Vellore632 014, IndiaCorrespondence[email protected]
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,
D. Thirumal KumarMedical Biotechnology Division, School of Biosciences and Technology (SBST), VIT University, Vellore632 014, IndiaView further author information
,
Chiranjib ChakrabortyDepartment of Bioinformatics, School of Computer and Information Sciences, Galgotias University, Greater Noida, IndiaView further author information
,
Kushi AnandDepartment of Biotechnology, Dr. M.G.R. Educational and Research Institute (University), Maduravoyal, Chennai600 095, IndiaView further author information
&
M. SureshDepartment of Biotechnology, Dr. M.G.R. Educational and Research Institute (University), Maduravoyal, Chennai600 095, IndiaView further author information
Pages 29-41 | Received 24 Oct 2014, Accepted 11 Jan 2015, Published online: 13 Feb 2015

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D. Thirumal Kumar & C. George Priya Doss. (2017) Role of E542 and E545 missense mutations of PIK3CA in breast cancer: a comparative computational approach. Journal of Biomolecular Structure and Dynamics 35:12, pages 2745-2757.
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D. Thirumal Kumar, C. George Priya Doss, P. Sneha, Iftikhar Aslam Tayubi, R. Siva, Chiranjib Chakraborty & R. Magesh. (2017) Influence of V54M mutation in giant muscle protein titin: a computational screening and molecular dynamics approach. Journal of Biomolecular Structure and Dynamics 35:5, pages 917-928.
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Articles from other publishers (21)

Mariem Ben Rekaya, Farah Sassi, Essya Saied, Linda Bel Haj Kacem, Nada Mansouri, Sinda Zarrouk, Saifeddine Azouz & Soumaya Rammeh. (2023) PIK3CA mutations in breast cancer: A Tunisian series. PLOS ONE 18:5, pages e0285413.
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Himshikha Sharma, Shweta Chaudhary, Sonam Nirwan, Rita Kakkar, Hui Shan Liew, May Lee Low, Chun‐Wai Mai, Ling‐Wei Hii, Chee‐Onn Leong & Marilyn Daisy Milton. (2022) N, N’ ‐Disubstituted Benzimidazolium Salts: Synthesis, Characterization, Micromolar Detection of Fe(III) ions in Aqueous system, Biological Evaluation and Molecular Docking Studies . ChemistrySelect 7:48.
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Manne Madhava Reddy, Rajagopal Desikan, Sanjay Naik, Sanjit Kumar, Thirumal Kumar D, George Priya Doss C & Akella Sivaramakrishna. (2022) Designing, Synthesis, and Anti‐Breast Cancer Activity of a Series of New Quinazolin‐4(1 H )‐one Derivatives . Chemistry & Biodiversity 19:12.
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D. Thirumal Kumar, S. Udhaya Kumar, Nikita Jain, Baviri Sowmya, Kamakshi Balsekar, R. Siva, Balu Kamaraj, Mariem Sidenna, C. George Priya Doss & Hatem Zayed. 2022. Protein Design and Structure. Protein Design and Structure 375 397 .
Minghan Jia, Ning Liao, Bo Chen, Guochun Zhang, Yulei Wang, Xuerui Li, Li Cao, Hsiaopei Mok, Chongyang Ren, Kai Li, Cheukfai Li, Lingzhu Wen, Jiali Lin, Guangnan Wei & Charles M. Balch. (2021) PIK3CA somatic alterations in invasive breast cancers: different spectrum from Caucasians to Chinese detected by next generation sequencing. Breast Cancer 28:3, pages 644-652.
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D. Thirumal Kumar, S. Udhaya Kumar, R. Magesh & C. George Priya Doss. 2021. 49 71 .
Hatem Zayed. (2020) The identification of highly upregulated genes in claudin-low breast cancer through an integrative bioinformatics approach. Computers in Biology and Medicine 127, pages 103806.
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Zhen Liu, Zhipan Hong, Hui Ma, Dake Yu & Pengpeng Qu. (2020) Key factors mediated by PI3K signaling pathway and related genes in endometrial carcinoma. Journal of Bioenergetics and Biomembranes 52:6, pages 465-473.
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Jing Lian, En-Wei Xu, Yan-Feng Xi, Hui-Wen Wang, Peng Bu, Jin-fen Wang & Li-Xia Wang. (2020) Clinical-Pathologic Analysis of Breast Cancer With PIK3CA Mutations in Chinese Women. Technology in Cancer Research & Treatment 19, pages 153303382095083.
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S. Udhaya Kumar, D. Thirumal Kumar, Pinky D. Mandal, Srivarshini Sankar, Rishin Haldar, Balu Kamaraj, Charles Emmanuel Jebaraj Walter, R. Siva, C. George Priya Doss & Hatem Zayed. 2020. Inflammatory Disorders - Part B. Inflammatory Disorders - Part B 349 377 .
Krami Al Mehdi, Benhnini Fouad, Elkarhat Zouhair, Belkady Boutaina, Naasse Yassine, Ait El Cadi Chaimaa, Sifeddine Najat, Rouba Hassan, Roky Rachida, Barakat Abdelhamid & Nahili Halima. (2019) Molecular Modelling and Dynamics Study of nsSNP in STXBP1 Gene in Early Infantile Epileptic Encephalopathy Disease. BioMed Research International 2019, pages 1-14.
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Himani Tanwar, D. Thirumal Kumar, C. George Priya Doss & Hatem Zayed. (2019) Bioinformatics classification of mutations in patients with Mucopolysaccharidosis IIIA. Metabolic Brain Disease 34:6, pages 1577-1594.
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D Thirumal Kumar, Maryam Umer Niazullah, Sadia Tasneem, E Judith, B Susmita, C George Priya Doss, E Selvarajan & Hatem Zayed. (2018) A computational method to characterize the missense mutations in the catalytic domain of GAA protein causing Pompe disease. Journal of Cellular Biochemistry 120:3, pages 3491-3505.
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D. Thirumal Kumar, Enid Mendonca, J. Priyadharshini Christy, C. George Priya Doss & Hatem Zayed. 2019. DNA Repair. DNA Repair 351 369 .
D. Thirumal Kumar, E. Judith, J. Priyadharshini Christy, R. Siva, Iftikhar Aslam Tayubi, Chiranjib Chakraborty, C. George Priya Doss & Hatem Zayed. 2019. Molecular Chaperones in Human Disorders. Molecular Chaperones in Human Disorders 341 407 .
D. Thirumal Kumar, P. Sneha, Jennifer Uppin, S. Usha & C. George Priya Doss. 2018. Protein-Protein Interactions in Human Disease, Part B. Protein-Protein Interactions in Human Disease, Part B 243 261 .
Himani Tanwar & C George Priya Doss. (2017) An Integrated Computational Framework to Assess the Mutational Landscape of α‐L‐Iduronidase IDUA Gene . Journal of Cellular Biochemistry 119:1, pages 555-565.
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Sneha P, Kumar Thirumal D, Himani Tanwar, Siva R, George Priya Doss C & Hatem Zayed. (2017) Structural Analysis of G1691S Variant in the Human Filamin B Gene Responsible for Larsen Syndrome: A Comparative Computational Approach . Journal of Cellular Biochemistry 118:7, pages 1900-1910.
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Himani Tanwar, P. Sneha, D. Thirumal Kumar, R. Siva, Charles Emmanuel Jebaraj Walter & C. George Priya Doss. 2017. Stress and Inflammation in Disorders. Stress and Inflammation in Disorders 105 125 .
C. George Priya Doss, Dima R. Alasmar, Reem I. Bux, P. Sneha, Fadheela Dad Bakhsh, Iman Al-Azwani, Rajaa El Bekay & Hatem Zayed. (2016) Genetic Epidemiology of Glucose-6-Phosphate Dehydrogenase Deficiency in the Arab World. Scientific Reports 6:1.
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Firoz Ahmad, Anuya Badwe, Geeta Verma, Simi Bhatia & Bibhu Ranjan Das. (2016) Molecular evaluation of PIK3CA gene mutation in breast cancer: determination of frequency, distribution pattern and its association with clinicopathological findings in Indian patients. Medical Oncology 33:7.
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