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Journal of Biomolecular Structure and Dynamics Volume 34, 2016 - Issue 11
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Research Articles

2-Deoxyglucose conjugated platinum (II) complexes for targeted therapy: design, synthesis, and antitumor activity

Qian MiTianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, Collaborative Innovation Center of Chemical Science and Engineering, School of Pharmaceutical Science and Technology, Tianjin University, 92 Weijin Road, Nankai District, Tianjin300072, P.R. ChinaView further author information
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Yuru MaTianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, Collaborative Innovation Center of Chemical Science and Engineering, School of Pharmaceutical Science and Technology, Tianjin University, 92 Weijin Road, Nankai District, Tianjin300072, P.R. ChinaView further author information
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Xiangqian GaoTianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, Collaborative Innovation Center of Chemical Science and Engineering, School of Pharmaceutical Science and Technology, Tianjin University, 92 Weijin Road, Nankai District, Tianjin300072, P.R. ChinaView further author information
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Ran LiuTianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, Collaborative Innovation Center of Chemical Science and Engineering, School of Pharmaceutical Science and Technology, Tianjin University, 92 Weijin Road, Nankai District, Tianjin300072, P.R. ChinaView further author information
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Pengxing LiuTianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, Collaborative Innovation Center of Chemical Science and Engineering, School of Pharmaceutical Science and Technology, Tianjin University, 92 Weijin Road, Nankai District, Tianjin300072, P.R. ChinaView further author information
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Yi MiCentral Institute of Pharmaceutical Research, CSPC Pharmaceutical Group, 226 Huanghe Road, Shijiazhuang, Hebei050035, P.R. ChinaView further author information
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Xuegang FuTianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, Collaborative Innovation Center of Chemical Science and Engineering, School of Pharmaceutical Science and Technology, Tianjin University, 92 Weijin Road, Nankai District, Tianjin300072, P.R. ChinaView further author information
&
Qingzhi GaoTianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, Collaborative Innovation Center of Chemical Science and Engineering, School of Pharmaceutical Science and Technology, Tianjin University, 92 Weijin Road, Nankai District, Tianjin300072, P.R. ChinaCorrespondence[email protected]
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Pages 2339-2350 | Received 15 Aug 2015, Accepted 27 Oct 2015, Published online: 30 Nov 2015

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Ahmet Altay, Sema Caglar & Bulent Caglar. (2022) Silver(I) complexes containing diclofenac and niflumic acid induce apoptosis in human-derived cancer cell lines. Archives of Physiology and Biochemistry 128:1, pages 69-79.
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Qiming Li, Chunyan Li, Longxiang Xie, Chenhui Zhang, Yonghong Feng & Jianping Xie. (2017) Characterization of a putative ArsR transcriptional regulator encoded by Rv2642 from Mycobacterium tuberculosis. Journal of Biomolecular Structure and Dynamics 35:9, pages 2031-2039.
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Articles from other publishers (16)

Jinxia Chen, Guirong Li, Dejuan Sun, Hua Li & Lixia Chen. (2024) Research progress of hexokinase 2 in inflammatory-related diseases and its inhibitors. European Journal of Medicinal Chemistry 264, pages 115986.
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Martin Conda-Sheridan. 2023. Self-Assembly of Peptides, Peptoids, Sugars, & Dendrimers. Self-Assembly of Peptides, Peptoids, Sugars, & Dendrimers.
Sema ÇAĞLAR, Ahmet ALTAY, Bülent ÇAĞLAR, Esma Kübra KAĞAN YENİÇERİ & Betül HARURLUOĞLU. (2022) In Vitro Cytotoxic Evaluation of a Silver(I) Complex Including Non-Steroidal Anti-Inflammatory Drug Niflumic Acid and 3-Picoline on Human-Derived Cancer Cell Lines. Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi 15:3, pages 736-748.
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Yu-Shien Sung, Baris Kerimoglu, Aikseng Ooi & Elisa Tomat. (2022) Aroylhydrazone Glycoconjugate Prochelators Exploit Glucose Transporter 1 (GLUT1) to Target Iron in Cancer Cells. ACS Medicinal Chemistry Letters 13:9, pages 1452-1458.
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Sabyasachi Banerjee & Subhasis Banerjee. (2022) Metal-based Complexes as Potential Anti-cancer Agents. Anti-Cancer Agents in Medicinal Chemistry 22:15, pages 2684-2707.
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Zhan Wang, Runlai Liu, Xin Zhang, Xing Chang, Minghuan Gao, Shuai Zhang, Qi Guan, Jun Sun, Daiying Zuo & Weige Zhang. (2022) Design, synthesis and biological evaluation of colchicine glycoconjugates as tubulin polymerization inhibitors. Bioorganic & Medicinal Chemistry 58, pages 116671.
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Sema Caglar, Ahmet Altay, Mehmet Kuzucu & Bulent Caglar. (2021) In Vitro Anticancer Activity of Novel Co(II) and Ni(II) Complexes of Non-steroidal Anti-inflammatory Drug Niflumic Acid Against Human Breast Adenocarcinoma MCF-7 Cells. Cell Biochemistry and Biophysics 79:4, pages 729-746.
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Junjie Fu, Jiaxin Yang, Peter H. Seeberger & Jian Yin. (2020) Glycoconjugates for glucose transporter-mediated cancer-specific targeting and treatment. Carbohydrate Research 498, pages 108195.
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Yu Wang, Xiaofei Cheng, Hongxia Zhao & Qingzhi Gao. (2019) 5-Fluorocytosine–Sugar Conjugates for Glucose Transporter-Mediated Tumor Targeting: Synthesis, Cytotoxicity, and Cellular Uptake Mechanism. Transactions of Tianjin University 25:6, pages 611-617.
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Ahmet Altay, Sema Caglar, Bulent Caglar & Zarife Sibel Sahin. (2019) Novel silver(I) complexes bearing mefenamic acid and pyridine derivatives: Synthesis, chemical characterization and in vitro anticancer evaluation. Inorganica Chimica Acta 493, pages 61-71.
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Nicolò Pettenuzzo, Leonardo Brustolin, Elisa Coltri, Alberto Gambalunga, Federica Chiara, Andrea Trevisan, Barbara Biondi, Chiara Nardon & Dolores Fregona. (2019) Cu II and Au III Complexes with Glycoconjugated Dithiocarbamato Ligands for Potential Applications in Targeted Chemotherapy . ChemMedChem 14:12, pages 1162-1172.
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Trevor W. Hambley. (2019) Transporter and protease mediated delivery of platinum complexes for precision oncology. JBIC Journal of Biological Inorganic Chemistry 24:4, pages 457-466.
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Reece G. Kenny & Celine J. Marmion. (2019) Toward Multi-Targeted Platinum and Ruthenium Drugs—A New Paradigm in Cancer Drug Treatment Regimens?. Chemical Reviews 119:2, pages 1058-1137.
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Zahra Yekke-ghasemi, Reza Takjoo, Mohammad Ramezani & Joel T. Mague. (2018) Molecular design and synthesis of new dithiocarbazate complexes; crystal structure, bioactivities and nano studies. RSC Advances 8:73, pages 41795-41809.
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Hira Choudhury, Bapi Gorain, Thiagarajan Madheswaran, Manisha Pandey, Prashant Kesharwani & Rakesh K. Tekade. 2018. Dosage Form Design Considerations. Dosage Form Design Considerations 473 512 .
Ran Liu, Zheng Fu, Meng Zhao, Xiangqian Gao, Hong Li, Qian Mi, Pengxing Liu, Jinna Yang, Zhi Yao & Qingzhi Gao. (2017) GLUT1-mediated selective tumor targeting with fluorine containing platinum(II) glycoconjugates. Oncotarget 8:24, pages 39476-39496.
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