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Journal of Biomolecular Structure and Dynamics Volume 36, 2018 - Issue 4
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Research Articles

7,8-benzoflavone binding to human cytochrome P450 3A4 reveals complex fluorescence quenching, suggesting binding at multiple protein sites

Glenn A. MarschPhysics Department, Grove City College, Grove City, PA, 16127-2104, USACorrespondence[email protected]
,
Benjamin T. CarlsonPhysics Department, Grove City College, Grove City, PA, 16127-2104, USA
&
F. Peter GuengerichDepartment of Biochemistry, Vanderbilt University School of Medicine, 638B Robinson Research Building, 2200 Pierce Avenue, Nashville, TN, 37232-0146, USACorrespondence[email protected]
Pages 841-860 | Received 29 Aug 2016, Accepted 20 Feb 2017, Published online: 20 Mar 2017

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Sansa Dutta, Dipayan Bose, Semanti Ghosh & Abhijit Chakrabarti. (2023) Spectrin: an alternate target for cytoskeletal drugs. Journal of Biomolecular Structure and Dynamics 41:14, pages 6534-6545.
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Surya Narayan Rath, Lingaraja Jena & Manorama Patri. (2020) Understanding ligands driven mechanism of wild and mutant aryl hydrocarbon receptor in presence of phytochemicals combating Parkinson’s disease: an in silico and in vivo study. Journal of Biomolecular Structure and Dynamics 38:3, pages 807-826.
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Meizi Wang, Suqing Wang, Jingjing Cui, Di Lian, Yuan Li, Yutong Du & Li Li. (2023) Interactions studies of CYP2D6 with quercetin and hyperoside by spectral analysis and molecular dynamics simulations. Luminescence.
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Yanzhou Tao, Yangyang Fan, Meizi Wang, Suqing Wang, Jing Jing Cui, Di Lian, Shuning Lu & Li Li. (2023) Comparative study of the interaction mechanism of astilbin, isoastilbin, and neoastilbin with CYP3A4. Luminescence 38:9, pages 1654-1667.
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Zdenka Lukáčová Bujňáková, Erika Dutková, Jana Jakubíková, Danka Cholujová, Rastislav Varhač, Larysa Borysenko & Inna Melnyk. (2023) Investigation of the Interaction between Mechanosynthesized ZnS Nanoparticles and Albumin Using Fluorescence Spectroscopy. Pharmaceuticals 16:9, pages 1219.
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Zdenka Lukáčová Bujňáková, Inna Melnyk, Erika Dutková, Rastislav Varhač, Jana Jakubíková, Danka Cholujová, Erika Tóthová, Liudmyla Storozhuk & Jaroslav Briančin. (2023) Nano-bio interface between As4S4 nanoparticles and albumin influenced by wet stirred media milling. International Journal of Pharmaceutics 640, pages 123046.
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Gianmarco Pascarella, Lorenzo Antonelli, Daniele Narzi, Theo Battista, Annarita Fiorillo, Gianni Colotti, Leonardo Guidoni, Veronica Morea & Andrea Ilari. (2023) Investigation of the Entry Pathway and Molecular Nature of σ1 Receptor Ligands. International Journal of Molecular Sciences 24:7, pages 6367.
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Yangyang Fan, Yanzhou Tao, Guiming Liu, Meizi Wang, Suqing Wang & Li Li. (2022) Interaction study of engeletin toward cytochrome P450 3A4 and 2D6 by multi-spectroscopy and molecular docking. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 264, pages 120311.
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Dumei Ma, Libo Zhang, Yingwu Yin, Yuxing Gao & Qian Wang. (2021) Spectroscopic studies of the interaction between phosphorus heterocycles and cytochrome P450. Journal of Pharmaceutical Analysis 11:6, pages 757-763.
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Yanzhou Tao, Yangyang Fan, Guiming Liu, Yuhang Zhang, Meizi Wang, Xiaolin Wang & Li Li. (2021) Interaction study of astilbin, isoastilbin and neoastilbin toward CYP2D6 by multi‐spectroscopy and molecular docking. Luminescence 36:6, pages 1412-1421.
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Julie Ducharme, Vanja Polic, Christopher J. Thibodeaux & Karine Auclair. (2021) Combining Small-Molecule Bioconjugation and Hydrogen–Deuterium Exchange Mass Spectrometry (HDX-MS) to Expose Allostery: the Case of Human Cytochrome P450 3A4. ACS Chemical Biology 16:5, pages 882-890.
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Bikash Dangi, Nadezhda Y. Davydova, Marc A. Maldonado, Armina Abbasi, Nikita E. Vavilov, Victor G. Zgoda & Dmitri R. Davydov. (2021) Effects of alcohol-induced increase in CYP2E1 content in human liver microsomes on the activity and cooperativity of CYP3A4. Archives of Biochemistry and Biophysics 698, pages 108677.
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Jaydeep Yadav, Erickson Paragas, Ken Korzekwa & Swati Nagar. (2020) Time-dependent enzyme inactivation: Numerical analyses of in vitro data and prediction of drug-drug interactions. Pharmacology & Therapeutics 206, pages 107449.
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Julie Ducharme, Vanja Polic & Karine Auclair. (2019) A Covalently Attached Progesterone Molecule Outcompetes the Binding of Free Progesterone at an Allosteric Site of Cytochrome P450 3A4. Bioconjugate Chemistry 30:6, pages 1629-1635.
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