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Research Articles

Structure-based design of selective histone deacetylase 6 zinc binding groups

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Pages 3166-3177 | Received 15 Apr 2019, Accepted 29 Jul 2019, Published online: 14 Aug 2019

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Guoyi Yan, Dongxiao Li, Xinxin Zhong, Ge Liu, Xueqin Wang, Yuanxiang Lu, Fangyuan Qin, Yuqi Guo, Shaofeng Duan & Deyu Li. (2021) Identification of HDAC6 selective inhibitors: pharmacophore based virtual screening, molecular docking and molecular dynamics simulation. Journal of Biomolecular Structure and Dynamics 39:6, pages 1928-1939.
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Sun Ju Kong, Gibeom Nam, Pulla Reddy Boggu, Gi Min Park, Ji Eun Kang, Hyun-Ju Park & Young Hoon Jung. (2023) Synthesis and biological evaluation of novel N-benzyltriazolyl-hydroxamate derivatives as selective histone deacetylase 6 inhibitors. Bioorganic & Medicinal Chemistry 79, pages 117154.
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Yunheng Li, Shenghu Sang, Weijie Ren, Yuqiong Pei, Yaoyao Bian, Yao Chen & Haopeng Sun. (2021) Inhibition of Histone Deacetylase 6 (HDAC6) as a therapeutic strategy for Alzheimer's disease: A review (2010–2020). European Journal of Medicinal Chemistry 226, pages 113874.
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Dušan Ružić, Nemanja Đoković, Katarina Nikolić & Zorica Vujić. (2021) Medicinal chemistry of histone deacetylase inhibitors. Arhiv za farmaciju 71:2, pages 73-100.
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Barbara Vergani, Giovanni Sandrone, Mattia Marchini, Chiara Ripamonti, Edoardo Cellupica, Elisabetta Galbiati, Gianluca Caprini, Gianfranco Pavich, Giulia Porro, Ilaria Rocchio, Maria Lattanzio, Marcello Pezzuto, Malgorzata Skorupska, Paola Cordella, Paolo Pagani, Pietro Pozzi, Roberta Pomarico, Daniela Modena, Flavio Leoni, Raffaella Perego, Gianluca Fossati, Christian Steinkühler & Andrea Stevenazzi. (2019) Novel Benzohydroxamate-Based Potent and Selective Histone Deacetylase 6 (HDAC6) Inhibitors Bearing a Pentaheterocyclic Scaffold: Design, Synthesis, and Biological Evaluation. Journal of Medicinal Chemistry 62:23, pages 10711-10739.
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