2,893
Views
27
CrossRef citations to date
0
Altmetric
Research Articles

Virtual screening and dynamics of potential inhibitors targeting RNA binding domain of nucleocapsid phosphoprotein from SARS-CoV-2

, , , &
Pages 4433-4448 | Received 08 May 2020, Accepted 29 May 2020, Published online: 22 Jun 2020

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Hoang Linh Nguyen, Nguyen Quoc Thai & Mai Suan Li. (2023) Identifying inhibitors of NSP16-NSP10 of SARS-CoV-2 from large databases. Journal of Biomolecular Structure and Dynamics 41:15, pages 7045-7054.
Read now
Dharmendra Kashyap, Rajarshi Roy, Parimal Kar & Hem Chandra Jha. (2023) Plant-derived active compounds as a potential nucleocapsid protein inhibitor of SARS-CoV-2: an in-silico study. Journal of Biomolecular Structure and Dynamics 41:10, pages 4770-4785.
Read now
Vladimir R. Chechetkin & Vasily V. Lobzin. (2022) Evolving ribonucleocapsid assembly/packaging signals in the genomes of the human and animal coronaviruses: targeting, transmission and evolution. Journal of Biomolecular Structure and Dynamics 40:21, pages 11239-11263.
Read now
Vanderlan Nogueira Holanda, Elton Marlon de Araújo Lima, Welson Vicente da Silva, Rafael Trindade Maia, Rafael de Lima Medeiros, Arabinda Ghosh, Vera Lúcia de Menezes Lima & Regina Celia Bressan Queiroz de Figueiredo. (2022) Identification of 1,2,3-triazole-phthalimide derivatives as potential drugs against COVID-19: a virtual screening, docking and molecular dynamic study. Journal of Biomolecular Structure and Dynamics 40:12, pages 5462-5480.
Read now

Articles from other publishers (22)

Gabriel Pedroso Viçozzi, Flávia Suelen de Oliveira Pereira, Rafael Santos da Silva, Julliano Guerin Leal, Joelma Menegazzi. Sarturi, Pablo Andrei Nogara, Oscar Endrigo Dorneles Rodrigues, João Batista Teixeira da Rocha & Daiana Silva Ávila. (2023) In silico evidences of Mpro inhibition by a series of organochalcogen-AZT derivatives and their safety in Caenorhabditis elegans. Journal of Trace Elements in Medicine and Biology 80, pages 127297.
Crossref
Palanisamy Prakash, Ekambaram Gayathiri, Mostafizur Rahaman, Govindasami Periyasami, Saravanan Pandiaraj, Thangaraj Pratheep, Kuppusamy Selvam, Somdatta Y. Chaudhari, Natesan Thirumalaivasan, John Thomas, Mehrnaz Hatami, Rajakumar Govindasamy & Muthu Thiruvengadam. (2023) Exploring the potential of targeting insulin-like growth factor-1 through network pharmacology, molecular docking, molecular dynamics, and experimental validation of antioxidant and anti-inflammatory activities. South African Journal of Botany 162, pages 707-718.
Crossref
Irene Boniardi, Angela Corona, Jerome Basquin, Claire Basquin, Jessica Milia, István Nagy, Enzo Tramontano & Luca Zinzula. (2023) Suramin inhibits SARS-CoV-2 nucleocapsid phosphoprotein genome packaging function. Virus Research 336, pages 199221.
Crossref
Muthu Kumar Thirunavukkarasu, Shanthi Veerappapillai & Ramanathan Karuppasamy. (2022) Computational biophysics approach towards the discovery of multi-kinase blockers for the management of MAPK pathway dysregulation. Molecular Diversity 27:5, pages 2093-2110.
Crossref
Deblina Rababi & Anish Nag. (2023) Evaluation of therapeutic potentials of selected phytochemicals against Nipah virus, a multi-dimensional in silico study. 3 Biotech 13:6.
Crossref
Aganze G. Mushebenge, Samuel C. Ugbaja, Sphamandla E. Mtambo, Thandokuhle Ntombela, Joy I. Metu, Oludotun Babayemi, Joy I. Chima, Patrick Appiah-Kubi, Adeshina I. Odugbemi, Mthobisi L. Ntuli, Rene Khan & Hezekiel M. Kumalo. (2023) Unveiling the Inhibitory Potentials of Peptidomimetic Azanitriles and Pyridyl Esters towards SARS-CoV-2 Main Protease: A Molecular Modelling Investigation. Molecules 28:6, pages 2641.
Crossref
Wenbing Wu, Ying Cheng, Hong Zhou, Changzhen Sun & Shujun Zhang. (2023) The SARS-CoV-2 nucleocapsid protein: its role in the viral life cycle, structure and functions, and use as a potential target in the development of vaccines and diagnostics. Virology Journal 20:1.
Crossref
Jiapu ZhangJiapu Zhang. 2023. Optimization-based Molecular Dynamics Studies of SARS-CoV-2 Molecular Structures. Optimization-based Molecular Dynamics Studies of SARS-CoV-2 Molecular Structures 597 637 .
Linda Jansen-Olliges, Shambhabi Chatterjee, Lili Jia, Frank Stahl, Christian Bär, Marc Stadler, Frank Surup & Carsten Zeilinger. (2022) Multiformin-Type Azaphilones Prevent SARS-CoV-2 Binding to ACE2 Receptor. Cells 12:1, pages 83.
Crossref
Hedyieh Karbasforooshan, Sofia Salari & Hesamoddin Hosseinjani. (2022) A Review on the New Indication of Nucleoside Reverse Transcriptase Inhibitors (NRTIs) in the Treatment of Coronavirus Disease 2019. Infectious Disorders - Drug Targets 22:5.
Crossref
Kaifu Gao, Rui Wang, Jiahui Chen, Limei Cheng, Jaclyn Frishcosy, Yuta Huzumi, Yuchi Qiu, Tom Schluckbier, Xiaoqi Wei & Guo-Wei Wei. (2022) Methodology-Centered Review of Molecular Modeling, Simulation, and Prediction of SARS-CoV-2. Chemical Reviews 122:13, pages 11287-11368.
Crossref
Anbuselvam Mohan, Nicole Rendine, Mohammed Kassim Sudheer Mohammed, Anbuselvam Jeeva, Hai-Feng Ji & Venkateswara Rao Talluri. (2021) Structure-based virtual screening, in silico docking, ADME properties prediction and molecular dynamics studies for the identification of potential inhibitors against SARS-CoV-2 Mpro. Molecular Diversity 26:3, pages 1645-1661.
Crossref
Bo Zhang, Junjie Tian, Qintao Zhang, Yan Xie, Kejia Wang, Shuyi Qiu, Keyu Lu & Yang Liu. (2022) Comparing the Nucleocapsid Proteins of Human Coronaviruses: Structure, Immunoregulation, Vaccine, and Targeted Drug. Frontiers in Molecular Biosciences 9.
Crossref
Jitendra Kumar Chaudhary, Rohitash Yadav, Pankaj Kumar Chaudhary, Anurag Maurya, Nimita Kant, Osamah Al Rugaie, Hoineiting Rebecca Haokip, Deepika Yadav, Rakesh Roshan, Ramasare Prasad, Apurva Chatrath, Dharmendra Singh, Neeraj Jain & Puneet Dhamija. (2021) Insights into COVID-19 Vaccine Development Based on Immunogenic Structural Proteins of SARS-CoV-2, Host Immune Responses, and Herd Immunity. Cells 10:11, pages 2949.
Crossref
Shikha Mudgal, Rohitash Yadav, Hoineiting Rebecca Haokip, Ananya Pandit & Y. Sheena Mary. (2021) Genomic variation and point mutations analysis of Indian COVID-19 patient samples submitted in GISAID database. Journal of the Indian Chemical Society 98:10, pages 100156.
Crossref
Jitendra Kumar Chaudhary, Rohitash Yadav, Pankaj Kumar Chaudhary, Anurag Maurya, Rakesh Roshan, Faizul Azam, Jyoti Mehta, Shailendra Handu, Ramasare Prasad, Neeraj Jain, Avaneesh Kumar Pandey & Puneet Dhamija. (2021) Host Cell and SARS-CoV-2-Associated Molecular Structures and Factors as Potential Therapeutic Targets. Cells 10:9, pages 2427.
Crossref
Majid Hassanzadeganroudsari, Amir Hossein Ahmadi, Niloufar Rashidi, Md Kamal Hossain, Amanda Habib & Vasso Apostolopoulos. (2021) Computational Chemistry to Repurposing Drugs for the Control of COVID-19. Biologics 1:2, pages 111-128.
Crossref
Sankar Muthumanickam, Arumugam Kamaladevi, Pandi Boomi, Shanmugaraj Gowrishankar & Shunmugiah Karutha Pandian. (2021) Indian Ethnomedicinal Phytochemicals as Promising Inhibitors of RNA-Binding Domain of SARS-CoV-2 Nucleocapsid Phosphoprotein: An In Silico Study. Frontiers in Molecular Biosciences 8.
Crossref
Tatsuhito Matsuo. (2021) Viewing SARS-CoV-2 Nucleocapsid Protein in Terms of Molecular Flexibility. Biology 10:6, pages 454.
Crossref
Rohitash Yadav, Jitendra Kumar Chaudhary, Neeraj Jain, Pankaj Kumar Chaudhary, Supriya Khanra, Puneet Dhamija, Ambika Sharma, Ashish Kumar & Shailendra Handu. (2021) Role of Structural and Non-Structural Proteins and Therapeutic Targets of SARS-CoV-2 for COVID-19. Cells 10:4, pages 821.
Crossref
Ahmed Rakib, Zulkar Nain, Saad Ahmed Sami, Shafi Mahmud, Ashiqul Islam, Shahriar Ahmed, Adnan Bin Faisul Siddiqui, S M Omar Faruque Babu, Payar Hossain, Asif Shahriar, Firzan Nainu, Talha Bin Emran & Jesus Simal-Gandara. (2021) A molecular modelling approach for identifying antiviral selenium-containing heterocyclic compounds that inhibit the main protease of SARS-CoV-2: an in silico investigation . Briefings in Bioinformatics 22:2, pages 1476-1498.
Crossref
Nicholas A. Wong & Milton H. SaierJr.Jr.. (2021) The SARS-Coronavirus Infection Cycle: A Survey of Viral Membrane Proteins, Their Functional Interactions and Pathogenesis. International Journal of Molecular Sciences 22:3, pages 1308.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.