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Research Articles

Mutational landscape of K-Ras substitutions at 12th position-a systematic molecular dynamics approach

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Pages 1571-1585 | Received 06 Apr 2020, Accepted 24 Sep 2020, Published online: 09 Oct 2020

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Articles from other publishers (13)

Alexandar L. Hansen, Xinyao Xiang, Chunhua Yuan, Lei Bruschweiler-Li & Rafael Brüschweiler. (2023) Excited-state observation of active K-Ras reveals differential structural dynamics of wild-type versus oncogenic G12D and G12C mutants. Nature Structural & Molecular Biology 30:10, pages 1446-1455.
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Finola Priyadharshini Chandrasekaran, Adarsh Vishal, Udita Arora, Udhaya Kumar S., Priya Doss George C. & Everette Jacob Remington Nelson. (2023) Molecular dynamics simulations corroborate recombinant expression studies carried out on three αIIb β‐propeller mutations reported in Indian Glanzmann thrombasthenia patients. Journal of Cellular Biochemistry 124:7, pages 989-1001.
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Xiaoqing Luo, Jianye Zhang, Yue Gao, Weifei Pan, Yayuan Yang, Xu Li, Lingfei Chen, Chang Wang & Yuqing Wang. (2023) Emerging roles of i-motif in gene expression and disease treatment. Frontiers in Pharmacology 14.
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Ankur Datta, S. Udhaya Kumar, Maria D'costa, Anusha Bothe, D. Thirumal Kumar, Hatem Zayed & C. George Priya Doss. 2023. Regulation of Downstream Targets. Regulation of Downstream Targets 21 52 .
Dolores Martínez-Rubio, Ángela Rodríguez-Prieto, Paula Sancho, Carmen Navarro-González, Nerea Gorría-Redondo, Javier Miquel-Leal, Clara Marco-Marín, Alison Jenkins, Mario Soriano-Navarro, Alberto Hernández, Belén Pérez-Dueñas, Pietro Fazzari, Sergio Aguilera-Albesa & Carmen Espinós. (2022) Protein misfolding and clearance in the pathogenesis of a new infantile onset ataxia caused by mutations in PRDX3 . Human Molecular Genetics 31:22, pages 3897-3913.
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Apoorva M. Kulkarni, Vikas Kumar, Shraddha Parate, Gihwan Lee, Sanghwa Yoon & Keun Woo Lee. (2022) Identification of New KRAS G12D Inhibitors through Computer-Aided Drug Discovery Methods. International Journal of Molecular Sciences 23:3, pages 1309.
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Julia Liang, Eleni Pitsillou, Katherine Ververis, Victor Guallar, Andrew Hung & Tom C. Karagiannis. (2022) Small molecule interactions with the SARS-CoV-2 main protease: In silico all-atom microsecond MD simulations, PELE Monte Carlo simulations, and determination of in vitro activity inhibition. Journal of Molecular Graphics and Modelling 110, pages 108050.
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Helena García-Cebollada, Alfonso López & Javier Sancho. (2022) Protposer: The web server that readily proposes protein stabilizing mutations with high PPV. Computational and Structural Biotechnology Journal 20, pages 2415-2433.
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D. Thirumal Kumar, Nishaat Shaikh, S. Udhaya Kumar & C. George Priya Doss. 2022. Disorders of Protein Synthesis. Disorders of Protein Synthesis 89 109 .
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S. Udhaya Kumar, Srivarshini Sankar, D. Thirumal Kumar, Salma Younes, Nadin Younes, R. Siva, C. George Priya Doss & Hatem Zayed. (2021) Molecular dynamics, residue network analysis, and cross-correlation matrix to characterize the deleterious missense mutations in GALE causing galactosemia III. Cell Biochemistry and Biophysics 79:2, pages 201-219.
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Thirumal Kumar D, Nishaat Shaikh, Udhaya Kumar S, George Priya Doss C & Hatem Zayed. (2021) Structure-Based Virtual Screening to Identify Novel Potential Compound as an Alternative to Remdesivir to Overcome the RdRp Protein Mutations in SARS-CoV-2. Frontiers in Molecular Biosciences 8.
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Udhaya Kumar S.Srivarshini Sankar, Salma Younes, Thirumal Kumar D.Muneera Naseer Ahmad, Sarah Samer Okashah, Balu Kamaraj, Abeer Mohammed Al-Subaie, George Priya Doss C.Hatem Zayed. (2020) Deciphering the Role of Filamin B Calponin-Homology Domain in Causing the Larsen Syndrome, Boomerang Dysplasia, and Atelosteogenesis Type I Spectrum Disorders via a Computational Approach. Molecules 25:23, pages 5543.
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