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Journal of Biomolecular Structure and Dynamics Volume 40, 2022 - Issue 8
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Research Articles

In silico inhibition of SGTP4 as a therapeutic target for the treatment of schistosomiasis

Tayo A. Adekiyaa Wits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy and Pharmacology, School of Therapeutic Science, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South AfricaORCID Iconhttps://orcid.org/0000-0002-3382-9080
ORCID Icon,
Raphael Taiwo Arulebab Department of Molecular and Cell Biology, Faculty of Science, University of Cape Town, Cape Town, South AfricaORCID Iconhttps://orcid.org/0000-0003-0879-344X
ORCID Icon,
Ashwil Kleinc Department of Biotechnology, Faculty of Natural Sciences, University of the Western Cape, Bellville, South AfricaORCID Iconhttps://orcid.org/0000-0002-5606-886X
ORCID Icon &
Adewale O. Fadakad Department of Science and Innovation/Mintek Nanotechnology Innovation Centre, Biolabels Node, Department of Biotechnology, Faculty of Natural Sciences, University of the Western Cape, Bellville, South AfricaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-3952-2098
ORCID Icon
Pages 3697-3705 | Received 05 Oct 2020, Accepted 06 Nov 2020, Published online: 23 Nov 2020

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Sayali Doiphode, Kiran Bharat Lokhande, Payel Ghosh, K. V. Swamy & Shuchi Nagar. (2023) Dual inhibition of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) by resveratrol derivatives in cancer therapy: in silico approach. Journal of Biomolecular Structure and Dynamics 41:17, pages 8571-8586.
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Fábio José Bonfim Cardoso, Luciana Pereira Xavier, Agenor Valadares Santos, Humberto D’Muniz Pereira, Lourivaldo da Silva Santos & Fábio Alberto de Molfetta. (2022) Identification of potential inhibitors of Schistosoma mansoni purine nucleoside phosphorylase from neolignan compounds using molecular modelling approaches. Journal of Biomolecular Structure and Dynamics 40:18, pages 8248-8260.
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Tayo A. Adekiya, Pradeep Kumar, Pierre P.D. Kondiah, Viness Pillay & Yahya E. Choonara. (2021) Synthesis and therapeutic delivery approaches for praziquantel: a patent review (2010-present). Expert Opinion on Therapeutic Patents 31:9, pages 851-865.
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Tran Nhat Phong Dao, Sunday Amos Onikanni, Adewale Oluwaseun Fadaka, Nicole Remaliah Samantha Sibuyi, Minh Hoang Le & Hen-Hong Chang. Phytotherapeutic potential of compounds identified from fractionated extracts of Morus alba L., as an inhibitor of interleukin-6 in the treatment of rheumatoid arthritis: computational approach. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-14.
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Bangwen Yue & Xiuli Wu. (2024) Antitumor studies on celastrol and its derivatives as RORα agonists and RORγ inhibitors based on Alphafold reverse docking strategy. Medicinal Chemistry Research 33:5, pages 779-795.
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Benson Otarigho & Mofolusho O. Falade. (2023) Natural Perylenequinone Compounds as Potent Inhibitors of Schistosoma mansoni Glutathione S-Transferase. Life 13:10, pages 1957.
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Aya Al-Naseri, Samar Al-Absi, Rashika El Ridi & Noha Mahana. (2021) A comprehensive and critical overview of schistosomiasis vaccine candidates. Journal of Parasitic Diseases 45:2, pages 557-580.
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