Advanced search
Publication Cover
Journal of Biomolecular Structure and Dynamics Volume 40, 2022 - Issue 11
Journal homepage
1,649
Views
10
CrossRef citations to date
0
Altmetric
Research Articles

Dual inhibition of SARS-CoV-2 spike and main protease through a repurposed drug, rutin

Anchala Kumaria School of Biotechnology, Jawaharlal Nehru University (JNU), New Delhi, India;b Department of Biotechnology, Teri School of Advanced Studies, New Delhi, IndiaCorrespondence[email protected]
View further author information
,
Vikrant Singh Rajputa School of Biotechnology, Jawaharlal Nehru University (JNU), New Delhi, IndiaCorrespondence[email protected]
View further author information
,
Priya Nagpala School of Biotechnology, Jawaharlal Nehru University (JNU), New Delhi, IndiaView further author information
,
Himanshi Kukretya School of Biotechnology, Jawaharlal Nehru University (JNU), New Delhi, IndiaView further author information
,
Sonam Groverc JH-Institute of Molecular Medicine, Jamia Hamdard, New Delhi, IndiaView further author information
&
Abhinav Grovera School of Biotechnology, Jawaharlal Nehru University (JNU), New Delhi, IndiaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-3296-7860View further author information
ORCID Icon
Pages 4987-4999 | Received 02 Jun 2020, Accepted 10 Dec 2020, Published online: 27 Dec 2020

Citations (10)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Debanjan Sen, Samhita Bhaumik, Pradip Debnath & Sudhan Debnath. (2022) Potentiality of Moringa oleifera against SARS-CoV-2: identified by a rational computer aided drug design method. Journal of Biomolecular Structure and Dynamics 40:16, pages 7517-7534.
Read now

Articles from other publishers (9)

Yoko Matsumura, Masahiro Kitabatake, Shin-ichi Kayano & Toshihiro Ito. (2023) Dietary Phenolic Compounds: Their Health Benefits and Association with the Gut Microbiota. Antioxidants 12:4, pages 880.
Crossref
T. S. Prathima, Md. Gulzar Ahmad, Ramanathan Karuppasamy, Kaushik Chanda & M. M. Balamurali. (2023) Investigation on Phyto‐active Constituent of Clerodendrum paniculatum as Therapeutic Agent against Viral Diseases . ChemistrySelect 8:4.
Crossref
Douglas B. Kell & Etheresia Pretorius. (2022) The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and therapeutic implications. Biochemical Journal 479:16, pages 1653-1708.
Crossref
Ileana Miclea. (2022) Secondary Metabolites with Biomedical Applications from Plants of the Sarraceniaceae Family. International Journal of Molecular Sciences 23:17, pages 9877.
Crossref
Ivan Kreft, Mateja Germ, Aleksandra Golob, Blanka Vombergar, Francesco Bonafaccia & Zlata Luthar. (2022) Impact of Rutin and Other Phenolic Substances on the Digestibility of Buckwheat Grain Metabolites. International Journal of Molecular Sciences 23:7, pages 3923.
Crossref
Vishma Pratap Sur, Madhab Kumar Sen & Katerina Komrskova. (2021) In Silico Identification and Validation of Organic Triazole Based Ligands as Potential Inhibitory Drug Compounds of SARS-CoV-2 Main Protease. Molecules 26:20, pages 6199.
Crossref
Pratibha Pandey, Fahad Khan, Faisal Abdulrahman Alzahrani, Huda A. Qari & Mohammad Oves. (2021) A Novel Approach to Unraveling the Apoptotic Potential of Rutin (Bioflavonoid) via Targeting Jab1 in Cervical Cancer Cells. Molecules 26:18, pages 5529.
Crossref
Kwang-Eun Choi, Jeong-Min Kim, JeeEun Rhee, Ae Kyung Park, Eun-Jin Kim & Nam Sook Kang. (2021) Molecular Dynamics Studies on the Structural Characteristics for the Stability Prediction of SARS-CoV-2. International Journal of Molecular Sciences 22:16, pages 8714.
Crossref
Bruno Rizzuti, Fedora Grande, Filomena Conforti, Ana Jimenez-Alesanco, Laura Ceballos-Laita, David Ortega-Alarcon, Sonia Vega, Hugh T. Reyburn, Olga Abian & Adrian Velazquez-Campoy. (2021) Rutin Is a Low Micromolar Inhibitor of SARS-CoV-2 Main Protease 3CLpro: Implications for Drug Design of Quercetin Analogs. Biomedicines 9:4, pages 375.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.