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Annals of Medicine Volume 56, 2024 - Issue 1
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Gastroenterology & Hepatology

Effect of on-demand vs continuous prescription of proton pump inhibitors on symptom burden and quality of life: results of a real-world randomized controlled trial in primary care patients with gastroesophageal reflux disease

Anna Andreassona Division of Psychobiology and Epidemiology, Department of Psychology, Stockholm University, Stockholm, Sweden;b Unit of Clinical Medicine, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden;c School of Psychological Sciences, Macquarie University, NSW, AustraliaCorrespondence[email protected]
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Lars Agréusd Division for Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, SwedenView further author information
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Nikolaos Mastellose Department of Primary Care and Public Health, School of Public Health, Imperial College London, London, UKView further author information
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Grzegorz Bliźniukf Faculty of Cybernetics, Military University of Technology, Warsaw, PolandView further author information
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Dorota Waśko-Czopnikg Department of Gastroenterology and Hepatology Medical University Wroclaw ul. Borowska 213, WroclawView further author information
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Agapi Angelakih Clinic of Social and Family Medicine, School of Medicine, University of Crete, Greece, HeraklionView further author information
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Eirini Theodosakih Clinic of Social and Family Medicine, School of Medicine, University of Crete, Greece, HeraklionView further author information
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Christos Lionish Clinic of Social and Family Medicine, School of Medicine, University of Crete, Greece, HeraklionView further author information
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Karin Heki Nivel, Netherlands Institute for Health Services Research, Utrecht, the NetherlandsView further author information
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Robert Verheiji Nivel, Netherlands Institute for Health Services Research, Utrecht, the Netherlands;j Tilburg School of Social and Behavioral Sciences, Tilburg University, Tilburg, the Netherlands;k Health Care Institute Netherlands, Diemen, the NetherlandsView further author information
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Ellen Wrightl School of Life Course & Population Sciences, Faculty of Life Sciences and Medicine, King’s College London, London, UKView further author information
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Stevo Durbabal School of Life Course & Population Sciences, Faculty of Life Sciences and Medicine, King’s College London, London, UKView further author information
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Jean Murism Department of Family Medicine, Maastricht University, Care and Public Health Research Institute, Maastricht, The NetherlandsView further author information
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Piotr Bródkan Department of Artificial Intelligence, Wroclaw University of Science and Technology, Wroclaw, PolandView further author information
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Stanislaw Saganowskin Department of Artificial Intelligence, Wroclaw University of Science and Technology, Wroclaw, PolandView further author information
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Jean-Francois Ethiéro Groupe de recherche interdisciplinaire en informatique de la santé (GRIIS.ca), Université de Sherbrooke, Sherbrooke, CanadaView further author information
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Vasa Curcinp Department of Informatics, King’s College London, London, UKView further author information
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Brendan Delaneyq Department of Department of Surgery and Cancer, Imperial College London, London, UKView further author information
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Article: 2354683 | Received 24 Sep 2023, Accepted 08 May 2024, Published online: 16 May 2024

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