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Research Article

Drug-activated nuclear receptors CAR and PXR

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Pages 172-182 | Published online: 08 Jul 2009

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Mengjing Zhao, Huan Zhao, Luomin Lin, Yi Wang, Menglin Chen & Baojian Wu. (2020) Nuclear receptor co-repressor RIP140 regulates diurnal expression of cytochrome P450 2b10 in mouse liver. Xenobiotica 50:10, pages 1139-1148.
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Xianxie Zhang, Yuguang Wang, Zengchun Ma, Qiande Liang, Xianglin Tang, Donghua Hu, Hongling Tan, Chengrong Xiao & Yue Gao. (2015) Tanshinone IIA ameliorates dextran sulfate sodium-induced inflammatory bowel disease via the pregnane X receptor. Drug Design, Development and Therapy 9, pages 6343-6362.
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Yue Yu, Yan Liu, Qian Li, Jiahui Sun, Haiou Lin & Gaofeng Liu. (2015) Effects of Guanxinning injection on rat cytochrome P450 isoforms activities in vivo and in vitro. Xenobiotica 45:6, pages 481-487.
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Maria Konstandi. (2013) Psychophysiological stress: a significant parameter in drug pharmacokinetics. Expert Opinion on Drug Metabolism & Toxicology 9:10, pages 1317-1334.
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Daniel M. Rotroff, Andrew L. Beam, David J. Dix, Adam Farmer, Kimberly M. Freeman, Keith A. Houck, Richard S. Judson, Edward L. LeCluyse, Matthew T. Martin, David M. Reif & Stephen S. Ferguson. (2010) Xenobiotic-Metabolizing Enzyme and Transporter Gene Expression in Primary Cultures of Human Hepatocytes Modulated by Toxcast Chemicals. Journal of Toxicology and Environmental Health, Part B 13:2-4, pages 329-346.
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Haishan Li & Hongbing Wang. (2010) Activation of xenobiotic receptors: driving into the nucleus. Expert Opinion on Drug Metabolism & Toxicology 6:4, pages 409-426.
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John YL Chiang. (2009) Hepatocyte nuclear factor 4α regulation of bile acid and drug metabolism. Expert Opinion on Drug Metabolism & Toxicology 5:2, pages 137-147.
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Xiaochao Ma, Jeffrey R Idle & Frank J Gonzalez. (2008) The pregnane X receptor: from bench to bedside. Expert Opinion on Drug Metabolism & Toxicology 4:7, pages 895-908.
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N. J. Hewitt, E. L. Lecluyse & S. S. Ferguson. (2007) Induction of hepatic cytochrome P450 enzymes: methods, mechanisms, recommendations, and correlations. Xenobiotica 37:10-11, pages 1196-1224.
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Marcella Martignoni, Geny M M Groothuis & Ruben de Kanter. (2006) Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction. Expert Opinion on Drug Metabolism & Toxicology 2:6, pages 875-894.
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Kevin M. Crofton & R. Thomas Zoeller. (2005) Mode of Action: Neurotoxicity Induced by Thyroid Hormone Disruption During Development—Hearing Loss Resulting From Exposure to PHAHs. Critical Reviews in Toxicology 35:8-9, pages 757-769.
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Frances M Sladek. (2003) Nuclear Receptors as Drug Targets: New Developments in Coregulators, Orphan Receptors and Major Therapeutic Areas. Expert Opinion on Therapeutic Targets 7:5, pages 679-684.
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