Advanced search
Publication Cover
Annals of Medicine Volume 39, 2007 - Issue 3
Submit an article Journal homepage
1,307
Views
56
CrossRef citations to date
0
Altmetric
REVIEW ARTICLE

The workings of the amyloid diseases

Vittorio Bellotti Center for Amyloidosis, Department of Biochemistry, Biotechnology Research Laboratories, Foundation IRCCS Policlinico San Matteo, Pavia, Italy
,
Mario Nuvolone Center for Amyloidosis, Department of Biochemistry, Biotechnology Research Laboratories, Foundation IRCCS Policlinico San Matteo, Pavia, Italy; Department of Internal Medicine, University of Pavia, Pavia, Italy
,
Sofia Giorgetti Center for Amyloidosis, Department of Biochemistry, Biotechnology Research Laboratories, Foundation IRCCS Policlinico San Matteo, Pavia, Italy
,
Laura Obici Center for Amyloidosis, Department of Biochemistry, Biotechnology Research Laboratories, Foundation IRCCS Policlinico San Matteo, Pavia, Italy
,
Giovanni Palladini Center for Amyloidosis, Department of Biochemistry, Biotechnology Research Laboratories, Foundation IRCCS Policlinico San Matteo, Pavia, Italy
,
Paola Russo Center for Amyloidosis, Department of Biochemistry, Biotechnology Research Laboratories, Foundation IRCCS Policlinico San Matteo, Pavia, Italy; Department of Internal Medicine, University of Pavia, Pavia, Italy
,
Francesca Lavatelli Center for Amyloidosis, Department of Biochemistry, Biotechnology Research Laboratories, Foundation IRCCS Policlinico San Matteo, Pavia, Italy; Department of Internal Medicine, University of Pavia, Pavia, Italy
,
Vittorio Perfetti Department of Internal Medicine, University of Pavia, Pavia, Italy
&
Giampaolo Merlini Center for Amyloidosis, Department of Biochemistry, Biotechnology Research Laboratories, Foundation IRCCS Policlinico San Matteo, Pavia, Italy
 show all
Pages 200-207 | Published online: 08 Jul 2009

Citations (56)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (4)

Michele Scivetti, Gianfranco Favia, Laura Fatone, Eugenio Maiorano & Vito Crincoli. (2016) Concomitant use of Congo red staining and confocal laser scanning microscopy to detect amyloidosis in oral biopsy: A clinicopathological study of 16 patients. Ultrastructural Pathology 40:2, pages 86-91.
Read now
Maria Lorenza Muiesan, Massimo Salvetti, Anna Paini, Claudia Agabiti Rosei, Giulia Rubagotti, Alessandro Negrinelli, Gina Gregorini, Giovanni Cancarini, Laura Calabresi, Guido Franceschini, Laura Obici, Stefano Perlini, Giampaolo Merlini & Enrico Agabiti Rosei. (2015) Vascular alterations in apolipoprotein A-I amyloidosis (Leu75Pro). A case–control study. Amyloid 22:3, pages 187-193.
Read now
Giovanni Montagna, Benedetta Cazzulani, Laura Obici, Carla Uggetti, Sofia Giorgetti, Riccardo Porcari, Rubina Ruggiero, P. Patrizia Mangione, Moreno Brambilla, Jacopo Lucchetti, Giovanna Guiso, Marco Gobbi, Giampaolo Merlini, Mario Salmona, Monica Stoppini, Giuseppe Villa & Vittorio Bellotti. (2013) Benefit of doxycycline treatment on articular disability caused by dialysis related amyloidosis. Amyloid 20:3, pages 173-178.
Read now
M. Lindhagen-Persson, M. Vestling, N. Reixach & A. Olofsson. (2008) Formation of cytotoxic transthyretin is not dependent on inter-molecular disulphide bridges commonly found within the amyloid form. Amyloid 15:4, pages 240-245.
Read now

Articles from other publishers (52)

Wing-Yin Leung, Henry H. L. Wu, Lauren Floyd, Arvind Ponnusamy & Rajkumar Chinnadurai. (2023) COVID-19 Infection and Vaccination and Its Relation to Amyloidosis: What Do We Know Currently?. Vaccines 11:7, pages 1139.
Crossref
Hisham F. Bahmad, Samantha Gogola, Lorena Burton, Ferial Alloush, Mike Cusnir, Michael Schwartz, Lydia Howard & Vathany Sriganeshan. (2023) Splenic Rupture Secondary to Amyloidosis: A Case Report and Review of the Literature. Hematology Reports 15:2, pages 370-383.
Crossref
Martin J. Kraus, Jacqueline M. Smits, Anna L. Meyer, Agita Strelniece, Arne van Kins, Udo Boeken, Alexander Reinecke, Zdenek Provaznik, Oliver Van Caenegem, Arnaud Ancion, Michael Berchtold-Herz, Johan J.A. Van Cleemput, Axel Haverich, Guenther Laufer, Jan Gummert, Matthias Karck, Gregor Warnecke, Philip W. Raake, Norbert Frey & Michael M. Kreusser. (2023) Outcomes in patients with cardiac amyloidosis undergoing heart transplantation: the eurotransplant experience. The Journal of Heart and Lung Transplantation 42:6, pages 778-785.
Crossref
Wladyslaw Grzeszczak, Edward Franek, Agnieszka Szypowska, Winicjusz Filipow, Mariusz Zięba, Paweł Kabicz & Barbara Więckowska. (2021) Incidence of non-hereditary amyloidosis in Poland. Annales Academiae Medicae Silesiensis 75, pages 99-106.
Crossref
Nadine M. Chiera, Sreenath Bolisetty, Robert Eichler, Raffaele Mezzenga & Patrick Steinegger. (2021) Removal of radioactive cesium from contaminated water by whey protein amyloids–carbon hybrid filters. RSC Advances 11:51, pages 32454-32458.
Crossref
Natasha Jeraj, Robert A. Hegele & Amanda J. Berberich. (2021) Apolipoprotein genetic variants and hereditary amyloidosis. Current Opinion in Lipidology 32:2, pages 132-140.
Crossref
Samantha Ash, Eran Shorer, Devyani Ramgobin, Maique Vo, Jonathan Gibbons, Reshma Golamari, Rahul Jain & Rohit Jain. (2021) Cardiac amyloidosis‐A review of current literature for the practicing physician. Clinical Cardiology 44:3, pages 322-331.
Crossref
Christopher D. Barrett, Kevin M. Alexander, Hongyu Zhao, Francois Haddad, Paul Cheng, Ronglih Liao, Matthew T. Wheeler, Michaela Liedtke, Stanley Schrier, Sally Arai, Dana Weisshaar & Ronald M. Witteles. (2020) Outcomes in Patients With Cardiac Amyloidosis Undergoing Heart Transplantation. JACC: Heart Failure 8:6, pages 461-468.
Crossref
Gabriel GianniniCynthia C. Nast. (2019) An Organ System–Based Approach to Differential Diagnosis of Amyloid Type in Surgical Pathology. Archives of Pathology & Laboratory Medicine 144:3, pages 379-387.
Crossref
Andrew Lytle, Farbod Darvishian & Ugur Ozerdem. (2019) Localized amyloidosis: A diagnostic pitfall in breast pathology. Pathology - Research and Practice 215:12, pages 152699.
Crossref
Christopher D. Barrett, Katharine Dobos, Michaela Liedtke, Mirela Tuzovic, Francois Haddad, Yukari Kobayashi, Richard Lafayette, Michael B. Fowler, Sally Arai, Stanley Schrier & Ronald M. Witteles. (2019) A Changing Landscape of Mortality for Systemic Light Chain Amyloidosis. JACC: Heart Failure 7:11, pages 958-966.
Crossref
Eric C. Ehman, M. Samir El-Sady, Marie F. Kijewski, Yiu Ming Khor, Sophia Jacob, Frederick L. Ruberg, Vaishali Sanchorawala, Heather Landau, Andrew J. Yee, Giada Bianchi, Marcelo F. Di Carli, Rodney H. Falk, Hyewon Hyun & Sharmila Dorbala. (2019) Early Detection of Multiorgan Light-Chain Amyloidosis by Whole-Body 18 F-Florbetapir PET/CT . Journal of Nuclear Medicine 60:9, pages 1234-1239.
Crossref
. 2019. Synopsis of Neurology, Psychiatry and Related Systemic Disorders. Synopsis of Neurology, Psychiatry and Related Systemic Disorders 3 53 .
Hassan Ramshini, Azam-Sadat Moghaddasi, Nasrin Mollania & Reza Khodarahmi. (2018) Diverse antithetical effects of the bio-compatible Ag-NPs on the hen egg lysozyme amyloid aggregation: from an efficient inhibitor to obscure inducer. Journal of the Iranian Chemical Society 16:1, pages 33-44.
Crossref
Kanti K. Yadav, Manoranjan Arakha, Basudeb Das, Bibekanand Mallick & Suman Jha. (2018) Preferential binding to zinc oxide nanoparticle interface inhibits lysozyme fibrillation and cytotoxicity. International Journal of Biological Macromolecules 116, pages 955-965.
Crossref
Ya-Xiong Tao & P. Michael Conn. (2018) Pharmacoperones as Novel Therapeutics for Diverse Protein Conformational Diseases. Physiological Reviews 98:2, pages 697-725.
Crossref
Tooba Naz Shamsi, Teeba Athar, Romana Parveen & Sadaf Fatima. (2017) A review on protein misfolding, aggregation and strategies to prevent related ailments. International Journal of Biological Macromolecules 105, pages 993-1000.
Crossref
Timco Koopman, Cindy Niedlich-den Herder, Coen A. Stegeman, Thera P. Links, Johan Bijzet, Bouke P.C. Hazenberg & Arjan Diepstra. (2017) Kidney Involvement in Systemic Calcitonin Amyloidosis Associated With Medullary Thyroid Carcinoma. American Journal of Kidney Diseases 69:4, pages 546-549.
Crossref
Romana Parveen, Tooba Naz Shamsi & Sadaf Fatima. (2017) Nanoparticles-protein interaction: Role in protein aggregation and clinical implications. International Journal of Biological Macromolecules 94, pages 386-395.
Crossref
Eli Muchtar, Francis K. Buadi, Angela Dispenzieri & Morie A. Gertz. (2016) Immunoglobulin Light-Chain Amyloidosis: From Basics to New Developments in Diagnosis, Prognosis and Therapy. Acta Haematologica 135:3, pages 172-190.
Crossref
Heather J. Landau, Morie A. Gertz & Raymond L. Comenzo. 2015. Thomas’ Hematopoietic Cell Transplantation. Thomas’ Hematopoietic Cell Transplantation 724 741 .
P. Michael Conn, Timothy P. Spicer, Louis Scampavia & Jo Ann Janovick. (2015) Assay strategies for identification of therapeutic leads that target protein trafficking. Trends in Pharmacological Sciences 36:8, pages 498-505.
Crossref
Saliha Esenboga, Deniz Çagdas Ayvaz, Arzu Saglam Ayhan, Banu Peynircioglu, Ozden Sanal & Ilhan Tezcan. (2015) CVID Associated with Systemic Amyloidosis. Case Reports in Immunology 2015, pages 1-4.
Crossref
Viviane L. Ndam Ngoungoure, Jan Schluesener, Paul F. Moundipa & Hermann Schluesener. (2015) Natural polyphenols binding to amyloid: A broad class of compounds to treat different human amyloid diseases. Molecular Nutrition & Food Research 59:1, pages 8-20.
Crossref
R Del Giudice, D M Monti, C Sarcinelli, A Arciello, R Piccoli & G-F Hu. (2014) Amyloidogenic variant of apolipoprotein A-I elicits cellular stress by attenuating the protective activity of angiogenin. Cell Death & Disease 5:3, pages e1097-e1097.
Crossref
Andrew C. Birkeland, Jonathan B. McHugh & Matthew E. Spector. (2014) Tracheobronchial Amyloidosis: A Case Report and Review of the Literature. Journal of Case Reports in Medicine 3, pages 1-3.
Crossref
Ahmed Abdalla Agab Eldour, Entisar Najeeb Mohmed Salih & Hussain Gadelkarim Ahmed. (2014) Incidence of Tuberculosis and Amyloidosis among Sudanese Patients Presented with Enlarged Nodes. Journal of Tropical Medicine 2014, pages 1-4.
Crossref
Giuseppe Grasso & Sylvestre Bonnet. (2014) Metal complexes and metalloproteases: targeting conformational diseases. Metallomics 6:8, pages 1346-1357.
Crossref
Giuseppe Grasso. 2014. Metal-Containing Enzymes. Metal-Containing Enzymes 115 142 .
Ashutosh D. Wechalekar, Simon W. Dubrey & Raymond L. Comenzo. 2013. Myeloma. Myeloma 174 189 .
Benjamin T. Fitzgerald, John Bashford & Gregory M. Scalia. (2013) The Return of the Normal Heart: Resolution of Cardiac Amyloidosis After Chemotherapy and Bone Marrow Transplantation. Heart, Lung and Circulation 22:8, pages 655-660.
Crossref
Gudrun Jonsdottir, Indiana Elin Ingolfsdottir, Finnbogi R. Thormodsson & Petur Henry Petersen. (2013) Endogenous aggregates of amyloidogenic cystatin C variant are removed by THP-1 cells in vitro and induce differentiation and a proinflammatory response. Neurobiology of Aging 34:5, pages 1389-1396.
Crossref
C. Magro Checa, J.L. Rosales Alexander, J. Salvatierra & E. Raya Álvarez. (2013) Amiloidosis. Medicine - Programa de Formación Médica Continuada Acreditado 11:34, pages 2065-2075.
Crossref
Kari Hemminki, Xinjun Li, Asta Försti, Jan Sundquist & Kristina Sundquist. (2012) Incidence and survival in non-hereditary amyloidosis in Sweden. BMC Public Health 12:1.
Crossref
Natalie A. Ciaccio, T. Steele Reynolds, C. Russell Middaugh & Jennifer S. Laurence. (2012) Influence of the Valine Zipper Region on the Structure and Aggregation of the Basic Leucine Zipper (bZIP) Domain of Activating Transcription Factor 5 (ATF5). Molecular Pharmaceutics 9:11, pages 3190-3199.
Crossref
Stefan O. SchönlandUte HegenbartTilmann BochtlerAnja MangatterMarion HansbergAnthony D. HoPeter Lohse & Christoph Röcken. (2012) Immunohistochemistry in the classification of systemic forms of amyloidosis: a systematic investigation of 117 patients. Blood 119:2, pages 488-493.
Crossref
Vittorio PerfettiGiovanni PalladiniSimona CasariniValentina Navazza, Paola RognoniLaura ObiciRosangela Invernizzi, Stefano Perlini, Catherine Klersy & Giampaolo Merlini. (2012) The repertoire of λ light chains causing predominant amyloid heart involvement and identification of a preferentially involved germline gene, IGLV1-44. Blood 119:1, pages 144-150.
Crossref
Farid Rahimi & Gal Bitan. 2012. Non-fibrillar Amyloidogenic Protein Assemblies - Common Cytotoxins Underlying Degenerative Diseases. Non-fibrillar Amyloidogenic Protein Assemblies - Common Cytotoxins Underlying Degenerative Diseases 1 36 .
Kristina Djinović-Carugo & Oliviero Carugo. 2012. Computational Medicine. Computational Medicine 145 158 .
G. Merlini. (2011) Reducing the amyloid burden through immunotherapy: a major therapeutic advance. Nephrology Dialysis Transplantation 26:5, pages 1471-1473.
Crossref
Francesca Lavatelli, Francesca Brambilla, Veronica Valentini, Paola Rognoni, Simona Casarini, Dario Di Silvestre, Vittorio Perfetti, Giovanni Palladini, Gabriele Sarais, Pierluigi Mauri & Giampaolo Merlini. (2011) A novel approach for the purification and proteomic analysis of pathogenic immunoglobulin free light chains from serum. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1814:3, pages 409-419.
Crossref
Sofia Giorgetti, Sara Raimondi, Katiuscia Pagano, Annalisa Relini, Monica Bucciantini, Alessandra Corazza, Federico Fogolari, Luca Codutti, Mario Salmona, Palma Mangione, Lino Colombo, Ada De Luigi, Riccardo Porcari, Alessandra Gliozzi, Massimo Stefani, Gennaro Esposito, Vittorio Bellotti & Monica Stoppini. (2011) Effect of Tetracyclines on the Dynamics of Formation and Destructuration of β2-Microglobulin Amyloid Fibrils. Journal of Biological Chemistry 286:3, pages 2121-2131.
Crossref
Gerald B. Appel, J.a.i. Radhakrishnan & Vivette D. D’Agati. 2011. Brenner and Rector's The Kidney. Brenner and Rector's The Kidney 1192 1277 .
Tom Pettersson & Yrjö T. Konttinen. (2010) Amyloidosis—Recent Developments. Seminars in Arthritis and Rheumatism 39:5, pages 356-368.
Crossref
R. P. E. Sarkany, S. M. Breathnach, A. A. M. Morris, K. Weismann & P. D. Flynn. 2010. Rook's Textbook of Dermatology. Rook's Textbook of Dermatology 1 103 .
Martina Koneracká, Andrea Antošová, Vlasta Závišová, Zuzana Gažová, Gábor Lancz, Alena Juríková, Natália Tomašovčová, Jozef Kováč, Martin Fabián & Peter Kopčanský. (2010) Preparation and characterization of albumin containing magnetic fluid as potential drug for amyloid diseases treatment. Physics Procedia 9, pages 254-257.
Crossref
Valerie L. Sim & Byron Caughey. (2009) Ultrastructures and strain comparison of under-glycosylated scrapie prion fibrils. Neurobiology of Aging 30:12, pages 2031-2042.
Crossref
M.V. Irigoyen Oyarzábal, M. López Lasanta, I. Ureña Garnica & A. Fernández-Nebro. (2009) Amiloidosis. Medicine - Programa de Formación Médica Continuada Acreditado 10:33, pages 2185-2191.
Crossref
Li Fei & Sarah Perrett. (2009) Effect of Nanoparticles on Protein Folding and Fibrillogenesis. International Journal of Molecular Sciences 10:2, pages 646-655.
Crossref
K.M. Colegrove, F.M.D. Gulland, K. Harr, D.K. Naydan & L.J. Lowenstine. (2009) Pathological Features of Amyloidosis in Stranded California Sea Lions (Zalophus californianus). Journal of Comparative Pathology 140:2-3, pages 105-112.
Crossref
E. Kvam & A. Messer. 2009. Handbook of Neurochemistry and Molecular Neurobiology. Handbook of Neurochemistry and Molecular Neurobiology 459 470 .
Gregory Darnell, Joseph P.R.O. Orgel, Reinhard Pahl & Stephen C. Meredith. (2007) Flanking Polyproline Sequences Inhibit β-Sheet Structure in Polyglutamine Segments by Inducing PPII-like Helix Structure. Journal of Molecular Biology 374:3, pages 688-704.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.