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Immunological Investigations
A Journal of Molecular and Cellular Immunology
Volume 48, 2019 - Issue 1
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Original Articles

Enhanced Anti-Leukemic Effects through Induction of Immunomodulating Microenvironment by Blocking CXCR4 and PD-L1 in an AML Mouse Model

Hee-Sun HwangLeukemia Research Institute, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaView further author information
,
A-Reum HanLeukemia Research Institute, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaView further author information
,
Ji Yoon LeeLeukemia Research Institute, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaView further author information
,
Gyeong Sin ParkDepartment of Pathology, College of Medicine, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, KoreaView further author information
,
Woo-Sung MinLeukemia Research Institute, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea;Department of Hematology, Seoul St. Mary’s Hematology Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaView further author information
&
Hee-Je KimLeukemia Research Institute, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea;Department of Hematology, Seoul St. Mary’s Hematology Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaCorrespondence[email protected]
View further author information
Pages 96-105 | Published online: 11 Sep 2018

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Khawar Ali Shahzad, Muhammad Naeem, Lei Zhang, Xin Wan, Shilong Song, Weiya Pei, Chen Zhao, Xiaoxiao Jin & Chuanlai Shen. (2020) Design and Optimization of PLGA Particles to Deliver Immunomodulatory Drugs for the Prevention of Skin Allograft Rejection. Immunological Investigations 49:7, pages 840-857.
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Zhenhai Zhou, Wanyi Lin, Xiaoyin Li, Yuling Huang, Jun Ren, Yixin Gao & Juan Li. (2019) Aberrant Phenotype and Function of Dendritic Cells in Adult B Lineage Acute Lymphoblastic Leukemia. Immunological Investigations 48:8, pages 781-793.
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Kate Rittenhouse-Olson. (2019) Thematic 2019 Letter from the Editor. Immunological Investigations 48:7, pages 673-679.
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Articles from other publishers (14)

Vaishali Bhardwaj & Stephen M. Ansell. (2023) Modulation of T-cell function by myeloid-derived suppressor cells in hematological malignancies. Frontiers in Cell and Developmental Biology 11.
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Başak Aru, Cemil Pehlivanoğlu, Zeynep Dal, Nida Nur Dereli-Çalışkan, Ege Gürlü & Gülderen Yanıkkaya-Demirel. (2023) A potential area of use for immune checkpoint inhibitors: Targeting bone marrow microenvironment in acute myeloid leukemia. Frontiers in Immunology 14.
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Kathryn A. Skelding, Daniel L. Barry, Danielle Z. Theron & Lisa F. Lincz. (2022) Bone Marrow Microenvironment as a Source of New Drug Targets for the Treatment of Acute Myeloid Leukaemia. International Journal of Molecular Sciences 24:1, pages 563.
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Shunjie Yu, Xiaotong Ren & Lijuan Li. (2022) Myeloid-derived suppressor cells in hematologic malignancies: two sides of the same coin. Experimental Hematology & Oncology 11:1.
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Chiel van Geffen, Constantin Heiss, Astrid Deißler & Saeed Kolahian. (2022) Pharmacological modulation of myeloid-derived suppressor cells to dampen inflammation. Frontiers in Immunology 13.
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Mahdieh Mehrpouri. (2022) The contributory roles of the CXCL12/CXCR4/CXCR7 axis in normal and malignant hematopoiesis: A possible therapeutic target in hematologic malignancies. European Journal of Pharmacology 920, pages 174831.
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Garrett M. Dancik, Ioannis F. Voutsas & Spiros Vlahopoulos. (2022) Lower RNA expression of ALDH1A1 distinguishes the favorable risk group in acute myeloid leukemia. Molecular Biology Reports 49:4, pages 3321-3331.
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Amit Choudhary. (2021) IMMUNE REGULATORY FUNCTION OF INTERFERON-GAMMA IN ACUTE LEUKEMIA. INDIAN JOURNAL OF APPLIED RESEARCH, pages 75-77.
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Long Su, Zheng Hu & Yong‐Guang Yang. (2021) Role of CXCR4 in the progression and therapy of acute leukaemia. Cell Proliferation 54:7.
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Kah Keng Wong, Rosline Hassan & Nik Soriani Yaacob. (2021) Hypomethylating Agents and Immunotherapy: Therapeutic Synergism in Acute Myeloid Leukemia and Myelodysplastic Syndromes. Frontiers in Oncology 11.
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Sophia Khaldoyanidi, Dirk Nagorsen, Anthony Stein, Gerrit Ossenkoppele & Marion Subklewe. (2021) Immune Biology of Acute Myeloid Leukemia: Implications for Immunotherapy. Journal of Clinical Oncology 39:5, pages 419-432.
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Harinad Maganti, Alissa Visram, Risa Shorr, Jill Fulcher, Mitchell Sabloff & David S. Allan. (2020) Plerixafor in combination with chemotherapy and/or hematopoietic cell transplantation to treat acute leukemia: A systematic review and metanalysis of preclinical and clinical studies. Leukemia Research 97, pages 106442.
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Franco Izzo, Stanley C. Lee, Asaf Poran, Ronan Chaligne, Federico Gaiti, Baptiste Gross, Rekha R. Murali, Sunil D. Deochand, Chelston Ang, Philippa Wyndham Jones, Anna S. Nam, Kyu-Tae Kim, Steven Kothen-Hill, Rafael C. Schulman, Michelle Ki, Priscillia Lhoumaud, Jane A. Skok, Aaron D. Viny, Ross L. Levine, Ephraim Kenigsberg, Omar Abdel-Wahab & Dan A. Landau. (2020) DNA methylation disruption reshapes the hematopoietic differentiation landscape. Nature Genetics 52:4, pages 378-387.
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Christian Bailly, Xavier Thuru & Bruno Quesnel. (2020) Combined cytotoxic chemotherapy and immunotherapy of cancer: modern times. NAR Cancer 2:1.
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