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Seminars in Ophthalmology Volume 24, 2009 - Issue 2: Angiogenesis and Ophthalmology
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Original

Review of the Ocular Angiogenesis Animal Models

Sandra R. Montezuma Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA
,
Demetrios Vavvas Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA
&
Joan W. Miller Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA
Pages 52-61 | Published online: 02 Jul 2009

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Sandra R. Montezuma, Luke D. Dolezal, Abrar A. Rageh, Kevin Mar, Michael Jordan & Deborah A. Ferrington. (2015) Lactoferrin Reduces Chorioretinal Damage in the Murine Laser Model of Choroidal Neovascularization. Current Eye Research 40:9, pages 946-953.
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George O. Waring & Charles S. Bouchard. 2011. Cornea. Cornea 47 79 .
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B. A. Kerr & T. V. Byzova. (2010)  B-crystallin: a novel VEGF chaperone. Blood 115:16, pages 3181-3183.
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