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Original

Invariant NKT Cells and Tolerance

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Pages 95-119 | Published online: 03 Aug 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Albert J Czaja. (2010) Animal models of autoimmune hepatitis. Expert Review of Gastroenterology & Hepatology 4:4, pages 429-443.
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Jerry Y Niederkorn. (2009) Role of NKT cells in anterior chamber-associated immune deviation. Expert Review of Clinical Immunology 5:2, pages 137-144.
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Nadir Kadri, Maria Blomqvist & Susanna L Cardell. (2008) Type II natural killer T cells: a new target for immunomodulation?. Expert Review of Clinical Immunology 4:5, pages 615-627.
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Albert J. Czaja. (2020) Exploring the Pathogenic Role and Therapeutic Implications of Interleukin 2 in Autoimmune Hepatitis. Digestive Diseases and Sciences 66:8, pages 2493-2512.
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Andreas Seidel, Corinna L. Seidel, Matthias Weider, Rüdiger Junker, Lina Gölz & Helga Schmetzer. (2020) Influence of Natural Killer Cells and Natural Killer T Cells on Periodontal Disease: A Systematic Review of the Current Literature. International Journal of Molecular Sciences 21:24, pages 9766.
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Jennifer Joscelyn, Javier Ochoa-Repáraz & Lloyd Kasper. 2020. Clinical Neuroimmunology. Clinical Neuroimmunology 17 42 .
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Fereshte Abdolmaleki, Seyed Mohammad Gheibi Hayat, Vanessa Bianconi, Thomas P. Johnston & Amirhossein Sahebkar. (2019) Atherosclerosis and immunity: A perspective. Trends in Cardiovascular Medicine 29:6, pages 363-371.
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Michael G. Strainic, Jinbo Liu, Fengqi An, Erin Bailey, Andrew Esposito, Jörg Hamann, Peter S. Heeger & M. Edward Medof. (2019) CD55 Is Essential for CD103+ Dendritic Cell Tolerogenic Responses that Protect against Autoimmunity. The American Journal of Pathology 189:7, pages 1386-1401.
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Javier Ochoa-Repáraz, Trevor O. Kirby & Lloyd H. Kasper. (2018) The Gut Microbiome and Multiple Sclerosis. Cold Spring Harbor Perspectives in Medicine 8:6, pages a029017.
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Hiroshi Keino, Shintaro Horie & Sunao Sugita. (2018) Immune Privilege and Eye-Derived T-Regulatory Cells. Journal of Immunology Research 2018, pages 1-12.
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Javier Ochoa-Repáraz & Lloyd H. Kasper. (2017) The influence of gut-derived CD39 regulatory T cells in CNS demyelinating disease. Translational Research 179, pages 126-138.
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A.J. Czaja. 2017. Liver Pathophysiology. Liver Pathophysiology 61 85 .
Kumiko Nishio, Takuya Miyagi, Tomohide Tatsumi, Kaori Mukai, Yoshinobu Yokoyama, Teppei Yoshioka, Ryotaro Sakamori, Hayato Hikita, Takahiro Kodama, Satoshi Shimizu, Minoru Shigekawa, Takatoshi Nawa, Harumasa Yoshihara, Naoki Hiramatsu, Hiroyuki Yamanaka, Ken-ichiro Seino & Tetsuo Takehara. (2015) Invariant natural killer T cell deficiency leads to the development of spontaneous liver inflammation dependent on γδT cells in mice. Journal of Gastroenterology 50:11, pages 1124-1133.
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Ricky H. Boghal, B.F. Stephenson & Simon C. Afford. 2015. Signaling Pathways in Liver Diseases. Signaling Pathways in Liver Diseases 110 129 .
Albert J. Czaja. (2015) Transitioning from Idiopathic to Explainable Autoimmune Hepatitis. Digestive Diseases and Sciences 60:10, pages 2881-2900.
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Aldo J. Montano-Loza & Albert J. Czaja. (2014) Cell Mediators of Autoimmune Hepatitis and Their Therapeutic Implications. Digestive Diseases and Sciences 60:6, pages 1528-1542.
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WENJIAN GUO, AISHU DONG, CHAO XING, XIAOJI LIN, XIAHUI PAN, YING LIN, BAOLING ZHU, MUQING HE & RONG-XING YAO. (2014) CD1d levels in peripheral blood of patients with acute myeloid leukemia and acute lymphoblastic leukemia. Oncology Letters 8:2, pages 825-830.
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A. J. Czaja. (2014) Review article: chemokines as orchestrators of autoimmune hepatitis and potential therapeutic targets. Alimentary Pharmacology & Therapeutics 40:3, pages 261-279.
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Kevin Tse, Harley Tse, John Sidney, Alex Sette & Klaus Ley. (2013) T cells in atherosclerosis. International Immunology 25:11, pages 615-622.
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Bart Legein, Lieve Temmerman, Erik A. L. Biessen & Esther Lutgens. (2013) Inflammation and immune system interactions in atherosclerosis. Cellular and Molecular Life Sciences 70:20, pages 3847-3869.
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Enrique Gómez, Cristobalina Mayorga, Francisca Gómez, Ana Belen Blázquez, Araceli Díaz-Perales, Miguel Blanca & María José Torres. (2013) Food allergy: management, diagnosis and treatment strategies. Immunotherapy 5:7, pages 755-768.
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Fenglei Li & Zhigang Tian. (2013) The liver works as a school to educate regulatory immune cells. Cellular & Molecular Immunology 10:4, pages 292-302.
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Marta Monteiro, Catarina F. Almeida, Ana Agua-Doce & Luis Graca. (2013) Induced IL-17–Producing Invariant NKT Cells Require Activation in Presence of TGF-β and IL-1β. The Journal of Immunology 190:2, pages 805-811.
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Bastiaan Schouten, Betty C.A.M. van Esch, Stephanie M. Lim, Gerard A. Hofman, Léon M.J. Knippels, Linette E.M. Willemsen, Arjan P. Vos & Johan Garssen. (2012) Invariant Natural Killer T Cells Contribute to the Allergic Response in Cows Milk Protein-Sensitized Mice. International Archives of Allergy and Immunology 159:1, pages 51-59.
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Yi-Ping Chuang, Chih-Hung Wang, Ning-Chi Wang, Deh-Ming Chang & Huey-Kang Sytwu. (2012) Modulatory Function of Invariant Natural Killer T Cells in Systemic Lupus Erythematosus. Clinical and Developmental Immunology 2012, pages 1-8.
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Linda D. Hazlett & Joan Stein-Streilein. 2012. Infection, Immune Homeostasis and Immune Privilege. Infection, Immune Homeostasis and Immune Privilege 1 29 .
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Michael Nowak & Ingo G.H. Schmidt-Wolf. (2011) Natural Killer T Cells Subsets in Cancer, Functional Defects in Prostate Cancer and Implications for Immunotherapy. Cancers 3:3, pages 3661-3675.
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Mark A. Exley, Lydia Lynch, Bindu Varghese, Michael Nowak, Nadia Alatrakchi & Steven P. Balk. (2011) Developing understanding of the roles of CD1d-restricted T cell subsets in cancer: Reversing tumor-induced defects. Clinical Immunology 140:2, pages 184-195.
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Mark A. Exley & Toshinori Nakayama. (2011) NKT-cell-based immunotherapies in clinical trials. Clinical Immunology 140:2, pages 117-118.
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Susanne Harner, Elfriede Noessner, Korinna Nadas, Anke Leumann-Runge, Matthias Schiemann, Fabienne L. Faber, Joachim Heinrich & Susanne Krauss-Etschmann. (2011) Cord Blood Vα24-Vβ11+ Natural Killer T Cells Display a Th2-Chemokine Receptor Profile and Cytokine Responses. PLoS ONE 6:1, pages e15714.
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Luc Van Kaer, Vrajesh V. Parekh & Lan Wu. (2010) Invariant natural killer T cells: bridging innate and adaptive immunity. Cell and Tissue Research 343:1, pages 43-55.
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Jennifer L. Joscelyn & Lloyd Kasper. 2011. Clinical Neuroimmunology. Clinical Neuroimmunology 15 40 .
Samuel A. LoCascio, Tatsuaki Morokata, Meredith Chittenden, Frederic I. Preffer, David M. Dombkowski, Giovanna Andreola, Kerry Crisalli, Tatsuo Kawai, Susan L. Saidman, Thomas R. Spitzer, Nina Tolkoff-Rubin, A. Benedict Cosimi, David H. Sachs & Megan Sykes. (2010) Mixed Chimerism, Lymphocyte Recovery, and Evidence for Early Donor-Specific Unresponsiveness in Patients Receiving Combined Kidney and Bone Marrow Transplantation to Induce Tolerance. Transplantation 90:12, pages 1607-1615.
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Albert J. Czaja. (2010) Emerging Opportunities for Site-Specific Molecular and Cellular Interventions in Autoimmune Hepatitis. Digestive Diseases and Sciences 55:10, pages 2712-2726.
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Marta Monteiro, Catarina F. Almeida, Marta Caridade, Julie C. Ribot, Joana Duarte, Ana Agua-Doce, Ivonne Wollenberg, Bruno Silva-Santos & Luis Graca. (2010) Identification of Regulatory Foxp3+ Invariant NKT Cells Induced by TGF-β. The Journal of Immunology 185:4, pages 2157-2163.
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Albert J. Czaja & Michael P. Manns. (2010) Advances in the Diagnosis, Pathogenesis, and Management of Autoimmune Hepatitis. Gastroenterology 139:1, pages 58-72.e4.
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Michael Nowak, Mohammed S. Arredouani, Adrian Tun-Kyi, Ingo Schmidt-Wolf, Martin G. Sanda, Steven P. Balk & Mark A. Exley. (2010) Defective NKT Cell Activation by CD1d+ TRAMP Prostate Tumor Cells Is Corrected by Interleukin-12 with alpha-Galactosylceramide. PLoS ONE 5:6, pages e11311.
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A. Esposito, B. Suedekum, J. Liu, F. An, J. Lass, M. G. Strainic, F. Lin, P. Heeger & M. E. Medof. (2010) Decay Accelerating Factor is Essential for Successful Corneal Engraftment. American Journal of Transplantation 10:3, pages 527-534.
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Robyn Cullen, Elitza Germanov, Takeshi Shimaoka & Brent Johnston. (2009) Enhanced Tumor Metastasis in Response to Blockade of the Chemokine Receptor CXCR6 Is Overcome by NKT Cell Activation. The Journal of Immunology 183:9, pages 5807-5815.
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Y Ilan. (2009) Alpha versus beta: are we on the way to resolve the mystery as to which is the endogenous ligand for natural killer T cells?. Clinical and Experimental Immunology 158:3, pages 300-307.
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Yaron Ilan. (2009) Oral tolerance: Can we make it work?. Human Immunology 70:10, pages 768-776.
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Hamid Bassiri & Kim E Nichols. (2009) It's up to you Egr2. Immunology & Cell Biology 87:5, pages 361-363.
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Nadia Alatrakchi & Margaret Koziel. (2009) Regulatory T cells and viral liver disease. Journal of Viral Hepatitis 16:4, pages 223-229.
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Ehud Zigmond, Zvi Shalev, Orit Pappo, Roslana Alper, Lidya Zolotarov & Yaron Ilan. (2008) NKT lymphocyte polarization determined by microenvironment signaling: A role for CD8+ lymphocytes and β-glycosphingolipids. Journal of Autoimmunity 31:2, pages 188-195.
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Elitza Germanov, Linnea Veinotte, Robyn Cullen, Erin Chamberlain, Eugene C. Butcher & Brent Johnston. (2008) Critical Role for the Chemokine Receptor CXCR6 in Homeostasis and Activation of CD1d-Restricted NKT Cells. The Journal of Immunology 181:1, pages 81-91.
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Mark G. Swain. (2008) Hepatic NKT cells: friend or foe?. Clinical Science 114:7, pages 457-466.
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Andrew L. Mellor & David H. Munn. (2008) Creating immune privilege: active local suppression that benefits friends, but protects foes. Nature Reviews Immunology 8:1, pages 74-80.
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