Advanced search
Publication Cover
International Reviews of Immunology Volume 28, 2009 - Issue 3-4
Submit an article Journal homepage
242
Views
26
CrossRef citations to date
0
Altmetric
Original

Role of IDO in Organ Transplantation: Promises and Difficulties

Stefan Löb Department of General, Visceral, and Transplant Surgery, University Hospital of Tübingen, Tübingen, Germany; Interfacultary Institue of Immunology, Department of Immunology, University of Tübingen, Tübingen, Germany
&
Alfred Königsrainer Department of General, Visceral, and Transplant Surgery, University Hospital of Tübingen, Tübingen, Germany
Pages 185-206 | Published online: 13 Aug 2009

Citations (26)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Miia Seppälä, Elina Halme, Lauri Tiilikainen, Annika Luukkainen, Jussi Laranne, Markus Rautiainen, Heini Huhtala, Timo Paavonen & Sanna Toppila-Salmi. (2016) The expression and prognostic relevance of indoleamine 2,3-dioxygenase in tongue squamous cell carcinoma. Acta Oto-Laryngologica 136:7, pages 729-735.
Read now

Articles from other publishers (25)

Pengbo Yang & Junhua Zhang. (2023) Indoleamine 2,3-Dioxygenase (IDO) Activity: A Perspective Biomarker for Laboratory Determination in Tumor Immunotherapy. Biomedicines 11:7, pages 1988.
Crossref
Aleksey S. Bulygin, Julia N. Khantakova, Nadezhda S. Shkaruba, Hiroshi Shiku & Sergey S. Sennikov. (2022) The role of metabolism on regulatory T cell development and its impact in tumor and transplantation immunity. Frontiers in Immunology 13.
Crossref
Meng Dou, Chenguang Ding, Bingxuan Zheng, Ge Deng, Kun Zhu, Cuixiang Xu, Wujun Xue, Xiaoming Ding, Jin Zheng & Puxun Tian. (2022) Immune-Related Genes for Predicting Future Kidney Graft Loss: A Study Based on GEO Database. Frontiers in Immunology 13.
Crossref
Nada Joe Melhem & Soraya Taleb. (2021) Tryptophan: From Diet to Cardiovascular Diseases. International Journal of Molecular Sciences 22:18, pages 9904.
Crossref
Danxin Wang, Liangxing Xiong, Yubin Wang, Jie Weng & Lianghui Gao. (2020) Immunomodulatory effects of sCD83 via induction of TGF-β1 and IDO: an in vitro and rat orthotopic liver transplantation study. Journal of Clinical and Experimental Hepatology.
Crossref
Evelyn Bracho-Sanchez, Azadeh Hassanzadeh, Maigan A. Brusko, Mark A. Wallet & Benjamin G. Keselowsky. (2019) Dendritic cells treated with exogenous indoleamine 2,3-dioxygenase maintain an immature phenotype and suppress antigen-specific T cell proliferation. Journal of Immunology and Regenerative Medicine 5, pages 100015.
Crossref
Qiaohuang Zeng, Feifei Qiu, Yuchao Chen, Cuihua Liu, Huazhen Liu, Chun-Ling Liang, Qunfang Zhang & Zhenhua Dai. (2019) Shikonin Prolongs Allograft Survival via Induction of CD4+FoxP3+ Regulatory T Cells. Frontiers in Immunology 10.
Crossref
Ji-Gang He, Qiao-Li Xie, Bei-Bei Li, Liang Zhou & Dan Yan. (2018) Exosomes Derived from IDO1-Overexpressing Rat Bone Marrow Mesenchymal Stem Cells Promote Immunotolerance of Cardiac Allografts. Cell Transplantation 27:11, pages 1657-1683.
Crossref
Laura V. de Vries, Isidor Minović, Casper F.M. FranssenMartijn van Faassen, Jan-Stephan F. SandersStefan P. BergerGerjan NavisIdo P. Kema & Stephan J. L. Bakker. (2017) The tryptophan/kynurenine pathway, systemic inflammation, and long-term outcome after kidney transplantation. American Journal of Physiology-Renal Physiology 313:2, pages F475-F486.
Crossref
Yang Li, Nan Hu, Dan Yang, Gregory Oxenkrug & Qing Yang. (2017) Regulating the balance between the kynurenine and serotonin pathways of tryptophan metabolism. The FEBS Journal 284:6, pages 948-966.
Crossref
Lukasz Kolodziej. (2013) Investigation of the kynurenine pathway in Indoleamine 2, 3 dioxygenase deficient mice with inflammatory arthritis. Transgenic Research 22:5, pages 1049-1054.
Crossref
Vikas R. Dharnidharka, Eihab Al Khasawneh, Sushil Gupta, Jonathan J. Shuster, Douglas W. Theriaque, Amir H. Shahlaee & Timothy J. Garrett. (2013) Verification of Association of Elevated Serum IDO Enzyme Activity With Acute Rejection and Low CD4-ATP Levels With Infection. Transplantation 96:6, pages 567-572.
Crossref
N. Lei, Y. Wang, W.-J. Zhang, J.-Z. Duan & G.-B. Yang. (2013) Indoleamine 2,3-dioxygenase is differentially expressed by different white blood cell populations of rhesus macaques ( Macaca mulatta ) . Journal of Medical Primatology 42:4, pages 192-203.
Crossref
Min Tian, Yi Lv, Chao Zhai, Haitao Zhu, Liang Yu & Bo Wang. (2013) Alternative Immunomodulatory Strategies for Xenotransplantation: CD80/CD86-CTLA4 Pathway-Modified Immature Dendritic Cells Promote Xenograft Survival. PLoS ONE 8:7, pages e69640.
Crossref
Kai Yu & Reginald M. Gorczynski. (2012) Persistence of Gene Expression Profile in CD200 Transgenic Skin Allografts Is Associated With Graft Survival on Retransplantation to Normal Recipients. Transplantation 94:1, pages 36-42.
Crossref
Judith Leibovici, Orit Itzhaki, Monica Huszar & Judith Sinai. (2011) Targeting the tumor microenvironment by immunotherapy: part 2. Immunotherapy 3:11, pages 1385-1408.
Crossref
Sebastian Schroecksnadel, Robert Sucher, Katharina Kurz, Dietmar Fuchs & Gerald Brandacher. (2011) Influence of immunosuppressive agents on tryptophan degradation and neopterin production in human peripheral blood mononuclear cells. Transplant Immunology 25:2-3, pages 119-123.
Crossref
Diana Vavrincova-Yaghi, Leo E. Deelman, Harry Goor, Marc Seelen, Ido P. Kema, Annemieke Smit-van Oosten, Dick Zeeuw, Robert H. Henning & Maria Sandovici. (2011) Gene therapy with adenovirus-delivered indoleamine 2,3-dioxygenase improves renal function and morphology following allogeneic kidney transplantation in rat. The Journal of Gene Medicine 13:7-8, pages 373-381.
Crossref
Vikas R. Dharnidharka, Sushil Gupta, Eihab Al Khasawneh, Allah Haafiz, Jonathan J. Shuster, Douglas W. Theriaque, Amir H. Shahlaee & Timothy J. Garrett. (2011) Immune biomarker panel monitoring utilizing IDO enzyme activity and CD4 ATP levels: Prediction of acute rejection vs. viral replication events. Pediatric Transplantation 15:3, pages 321-328.
Crossref
Cailin Moira Wilke & Weiping Zou. (2011) T lymphocytes to IDO+ cells: check. Blood 117:7, pages 2082-2083.
Crossref
Richeng Mao, Jiming Zhang, Dong Jiang, Dawei Cai, Jessica M. Levy, Andrea Cuconati, Timothy M. Block, Ju-Tao Guo & Haitao Guo. (2011) Indoleamine 2,3-Dioxygenase Mediates the Antiviral Effect of Gamma Interferon against Hepatitis B Virus in Human Hepatocyte-Derived Cells. Journal of Virology 85:2, pages 1048-1057.
Crossref
Hatem Soliman, Melanie Mediavilla-Varela & Scott Antonia. (2010) Indoleamine 2,3-Dioxygenase. The Cancer Journal 16:4, pages 354-359.
Crossref
Richard E. Kast & Eric L. Altschuler. (2010) Indoleamine 2,3-dioxygenase-expressing mature human monocyte-derived dendritic cells expand potent autologous regulatory T cells: Consideration of triamterene to treat lupus. Medical Hypotheses 74:5, pages 957.
Crossref
Birgit JürgensJulia RabergerDietmar FuchsAndreas Heitger. (2010) Indoleamine 2,3-Dioxygenase in Human Hematopoietic Stem Cell Transplantation. International Journal of Tryptophan Research 3, pages IJTR.S4076.
Crossref
Roberto A. Maldonado & Ulrich H. von Andrian. 2010. 111 165 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.