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Lead Article

Protective Effects of Vitamin C on Cisplatin-Induced Renal Damage: A Light and Electron Microscopic Study

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Pages 1-8 | Published online: 07 Jul 2009

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Read on this site (4)

Dila Şener Akçora, Deniz Erdoğan, Gülnur Take Kaplanoğlu, Gül Eser Göktaş, Uğur Şeker & Çiğdem Elmas. (2022) Electron microscopic investigation of benzo(a)pyrene-induced alterations in the rat kidney tissue and the protective effects of curcumin. Ultrastructural Pathology 46:6, pages 519-530.
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Ying Wang, Peng-Chao Hu, Fang-Fang Gao, Jia-Wei Lv, Shuai Xu, Chang-Chun Kuang, Lei Wei & Jing-Wei Zhang. (2014) The Protective Effect of Curcumin on Hepatotoxicity and Ultrastructural Damage Induced by Cisplatin. Ultrastructural Pathology 38:5, pages 358-362.
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Antonio Macciò & Clelia Madeddu. (2013) Cisplatin: an old drug with a newfound efficacy – from mechanisms of action to cytotoxicity. Expert Opinion on Pharmacotherapy 14:13, pages 1839-1857.
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M. A. Carvalho Rodrigues, G. Gobe, N. A. G. Santos & A. C. Santos. (2012) Carvedilol Protects Against Apoptotic Cell Death Induced by Cisplatin in Renal Tubular Epithelial Cells. Journal of Toxicology and Environmental Health, Part A 75:16-17, pages 981-990.
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Articles from other publishers (26)

Zihui Yu, Ziying Xu, Yuan Liang, Pengbin Yin, Yue Shi, Jiayi Yu, Junfeng Hao, Ting Wang & Weimin Ci. (2022) Vitamin C Deficiency Causes Cell Type–Specific Epigenetic Reprogramming and Acute Tubular Necrosis in a Mouse Model. Journal of the American Society of Nephrology 33:3, pages 531-546.
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Shaloam Dasari, Sylvianne Njiki, Ariane Mbemi, Clement G. Yedjou & Paul B. Tchounwou. (2022) Pharmacological Effects of Cisplatin Combination with Natural Products in Cancer Chemotherapy. International Journal of Molecular Sciences 23:3, pages 1532.
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Oktay KAYA, Deniz ERÇETİN, Muhammed Ali AYDIN & Melike SAPMAZ. (2021) İstemli Egzersizin Sıçanlarda Fruktozdan Zengin Beslenmeyle Uyarılan Böbrek Fonksiyon Bozukluğu ve Oksidan Durumu Düzeltici EtkisiImproving Effect of Voluntary Exercise on High Fructose Diet Induced Kidney Dysfunction and Oxidant Status in Rats.. Uludağ Üniversitesi Tıp Fakültesi Dergisi 47:2, pages 181-187.
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Kim Long Vu-Huynh, Thi Hong Van Le, Huy Truong Nguyen, Hyung Min Kim, Ki Sung Kang, Jeong Hill Park & Minh Duc Nguyen. (2019) Increase in Protective Effect of Panax vietnamensis by Heat Processing on Cisplatin-Induced Kidney Cell Toxicity. Molecules 24:24, pages 4627.
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Elvan Şahin, Tuba Demirci & Semin Gedikli. (2018) Kronik Stres ve Böbrek: Sıçan Modeli Üzerinde Morfometrik ve Histopatolojik Çalışma. Sakarya Medical Journal 7:4, pages 168-175.
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Pablinny Moreira Galdino, Layse Nunes Alexandre, Lílian Fernanda Pacheco, Ruy de Souza Lino Junior, José Realino de Paula, Gustavo Rodrigues Pedrino, Carlos Henrique Xavier & Patrícia Maria Ferreira. (2017) Nephroprotective effect of Rudgea viburnoides (Cham.) Benth leaves on gentamicin-induced nephrotoxicity in rats. Journal of Ethnopharmacology 201, pages 100-107.
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George J. Dugbartey, Luke J. Peppone & Inge A.M. de Graaf. (2016) An integrative view of cisplatin-induced renal and cardiac toxicities: Molecular mechanisms, current treatment challenges and potential protective measures. Toxicology 371, pages 58-66.
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Thyago Proença de Moraes, Maria Cláudia Cruz Andreoli, Maria Eugênia Canziani, Dirceu Reis da Silva, Jacqueline Costa Teixeira Caramori, Daniela Ponce, Hélio Vida Cassi, Kleyton de Andrade Bastos, Danyelle Romana Alves Rio, Sergio Wyton Pinto, Sebastião Rodrigues Ferreira Filho, Ludimila Guedim de Campos, Marcia Olandoski, José Carolino Divino-Filho & Roberto Pecoits-Filho. (2015) Icodextrin reduces insulin resistance in non-diabetic patients undergoing automated peritoneal dialysis: results of a randomized controlled trial (STARCH). Nephrology Dialysis Transplantation 30:11, pages 1905-1911.
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Maria Salman, Imrana Naseem, Iftekhar Hassan, Aijaz A. Khan & Ibrahim M. Alhazza. (2015) Riboflavin Arrests Cisplatin-Induced Neurotoxicity by Ameliorating Cellular Damage in Dorsal Root Ganglion Cells. BioMed Research International 2015, pages 1-5.
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Amal A. Mahdy & Kadreya E. El-Morshdy. (2014) Role of losartan on the renal cortex damage induced by cisplatin in adult male albino rats. The Egyptian Journal of Histology 37:3, pages 480-491.
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C. Máthé, G. Szénási, A. Sebestény, A. Blázovics, K. Szentmihályi, P. Hamar & M. Albert. (2013) Protective effect of CV247 against cisplatin nephrotoxicity in rats. Human & Experimental Toxicology 33:8, pages 789-799.
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Roya Rastghalam, Mehdi Nematbakhsh, Mehrnoosh Bahadorani, Fatemeh Eshraghi-Jazi, Ardeshir Talebi, Maryam Moeini, Farzaneh Ashrafi & Soheila Shirdavani. (2014) Angiotensin Type-1 Receptor Blockade May Not Protect Kidney against Cisplatin-Induced Nephrotoxicity in Rats. ISRN Nephrology 2014, pages 1-7.
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Iftekhar HassanSandesh ChibberAijaz A. KhanImrana Naseem. (2013) Cisplatin-Induced Neurotoxicity In Vivo Can Be Alleviated by Riboflavin Under Photoillumination . Cancer Biotherapy and Radiopharmaceuticals 28:2, pages 160-168.
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Saban Celebi, M. Mustafa Gurdal, M. Haluk Ozkul, Husamettin Yasar & H. Huseyin Balikci. (2012) The effect of intratympanic vitamin C administration on cisplatin-induced ototoxicity. European Archives of Oto-Rhino-Laryngology 270:4, pages 1293-1297.
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Mohamed A. Dkhil, Saleh Al-Quraishy, Ahmed M. Aref, Mohamed S. Othman, Kamal M. El-Deib & Ahmed E. Abdel Moneim. (2013) The Potential Role of Azadirachta indica Treatment on Cisplatin-Induced Hepatotoxicity and Oxidative Stress in Female Rats . Oxidative Medicine and Cellular Longevity 2013, pages 1-9.
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Neife Aparecida Guinaim dos Santos, Maria Augusta Carvalho Rodrigues, Nadia Maria Martins & Antonio Cardozo dos Santos. (2012) Cisplatin-induced nephrotoxicity and targets of nephroprotection: an update. Archives of Toxicology 86:8, pages 1233-1250.
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Neife Ap. Guinaim dos Santos & Antonio Cardozo dos Santos. 2012. Oxidative Stress in Cancer Biology and Therapy. Oxidative Stress in Cancer Biology and Therapy 407 425 .
Kerim ÇayırAli KaradenizNejdet ŞimşekSerap YıldırımEmre KarakuşAdem KaraHürrem Turan AkkoyunEmin Şengül. (2011) Pomegranate Seed Extract Attenuates Chemotherapy-Induced Acute Nephrotoxicity and Hepatotoxicity in Rats. Journal of Medicinal Food 14:10, pages 1254-1262.
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Meryem Akpolat, Mehmet Kanter, Yeter Topcu‐Tarladacalisir & Nurettin Aydogdu. (2010) Protective Effect of flaxseed oil on renal injury in hyperlipidaemic rats: the effect of flaxseed oil on hyperlipidaemia. Phytotherapy Research 25:6, pages 796-802.
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Kilarkaje Narayana. (2010) Cisplatin induces duplex 3? overhangs and 5? blunt ends in epididymal epithelium in a Bax-dependent manner without any protection from l-ascorbic acid. European Journal of Pharmacology 641:2-3, pages 238-245.
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I. Hassan, S. Chibber & I. Naseem. (2010) Ameliorative effect of riboflavin on the cisplatin induced nephrotoxicity and hepatotoxicity under photoillumination. Food and Chemical Toxicology 48:8-9, pages 2052-2058.
Crossref
M.A. Carvalho Rodrigues, J.L. Rodrigues, N.M. Martins, F. Barbosa, C. Curti, N.A.G. Santos & A.C. Santos. (2010) Carvedilol protects against the renal mitochondrial toxicity induced by cisplatin in rats. Mitochondrion 10:1, pages 46-53.
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Daljit K. Hothi, Lesley Rees, Jan Marek, James Burton & Christopher W. McIntyre. (2009) Pediatric Myocardial Stunning Underscores the Cardiac Toxicity of Conventional Hemodialysis Treatments. Clinical Journal of the American Society of Nephrology 4:4, pages 790-797.
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Kerim Cayir, Ali Karadeniz, Abdulkadir Yildirim, Yildiray Kalkan, Akar Karakoc, Mustafa Keles & Salim Tekin. (2009) Protective effect of L-carnitine against cisplatin-induced liver and kidney oxidant injury in rats. Open Medicine 4:2.
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Mehmet Kanter & Meryem Akpolat. (2008) Vitamin C protects against ionizing radiation damage to goblet cells of the ileum in rats. Acta Histochemica 110:6, pages 481-490.
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P. Devarajan. (2008) Neutrophil gelatinase-associated lipocalin--an emerging troponin for kidney injury. Nephrology Dialysis Transplantation 23:12, pages 3737-3743.
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