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Renal Failure Volume 40, 2018 - Issue 1
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Laboratory Study

The protective effects of rapamycin on cell autophagy in the renal tissues of rats with diabetic nephropathy via mTOR-S6K1-LC3II signaling pathway

Lei LiuDepartment of Nephrology, Shandong University Qilu Hospital, Jinan, P.R. China; View further author information
,
Lijuan YangDepartment of Physiology, Bengbu Medical College, Bengbu, P.R. China; View further author information
,
Baochao ChangDepartment of Nephrology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, P.R. ChinaView further author information
,
Jiqiang ZhangDepartment of Nephrology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, P.R. ChinaView further author information
,
Yaling GuoDepartment of Nephrology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, P.R. ChinaView further author information
&
Xiangdong YangDepartment of Nephrology, Shandong University Qilu Hospital, Jinan, P.R. China; Correspondence[email protected] [email protected]
View further author information
Pages 492-497 | Received 05 Dec 2017, Accepted 07 Jun 2018, Published online: 11 Sep 2018

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Jiayong Xie, Ying Yuan, Gang Yao, Zhi Chen, Wenjuan Yu & Qiang Zhu. (2021) Nucleoporin 160 (NUP160) inhibition alleviates diabetic nephropathy by activating autophagy. Bioengineered 12:1, pages 6390-6402.
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Articles from other publishers (20)

Yi Chen, Yashpal S. Kanwar, Xueqin Chen & Ming Zhan. (2024) Aging and Diabetic Kidney Disease: Emerging Pathogenetic Mechanisms and Clinical Implications. Current Medicinal Chemistry 31:6, pages 697-725.
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Che-Hao Tseng, Kavya M. Shah, I-Jen Chiu & Li-Li Hsiao. (2023) The Role of Autophagy in Type 2 Diabetic Kidney Disease Management. Cells 12:23, pages 2691.
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Weiyan Lai, Dan Luo, Yin Li, Yuanqing Li, Qianqian Wang, Zhaoyong Hu, Zengchun Ye & Hui Peng. (2023) Irisin ameliorates diabetic kidney disease by restoring autophagy in podocytes. The FASEB Journal 37:10.
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Yu Wang, Mingyue Jin, Chak Kwong Cheng & Qiang Li. (2023) Tubular injury in diabetic kidney disease: molecular mechanisms and potential therapeutic perspectives. Frontiers in Endocrinology 14.
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Yu-Peng Han, Li-Juan Liu, Jia-Lin Yan, Meng-Yuan Chen, Xiang-Fei Meng, Xin-Ru Zhou & Ling-Bo Qian. (2023) Autophagy and its therapeutic potential in diabetic nephropathy. Frontiers in Endocrinology 14.
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Moein Ala. (2023) Sestrin2 Signaling Pathway Regulates Podocyte Biology and Protects against Diabetic Nephropathy. Journal of Diabetes Research 2023, pages 1-15.
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Xiujie Shi, Meiying Chang, Mingming Zhao, Yue Shi & Yu Zhang. (2022) Traditional Chinese medicine compounds ameliorating glomerular diseases via autophagy: A mechanism review. Biomedicine & Pharmacotherapy 156, pages 113916.
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Marziyeh Salami, Raziyeh Salami, Alireza Mafi, Mohammad-Hossein Aarabi, Omid Vakili & Zatollah Asemi. (2022) Therapeutic Potential of Resveratrol in Diabetic Nephropathy According to Molecular Signaling. Current Molecular Pharmacology 15:5, pages 716-735.
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Jiayi Xu, Xiaomeng Shan, Chunwei Chen, Yanbin Gao, Dawei Zou, Xiaolei Wang, Tao Wang & Yimin Shi. (2022) Tangshenning Attenuates High Glucose-Induced Podocyte Injury via Restoring Autophagy Activity through Inhibiting mTORC1 Activation. Journal of Diabetes Research 2022, pages 1-11.
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Quanhui Tan, Jie chen, Gao Gao, Yizhang, Xiaohua Chen, Yongsheng Yu, Guoqin Zang & Zhenghao Tang. (2022) Adenovirus vector encoding TPPII ignites HBV‐specific CTL response by activating autophagy in CD8+ T cell. Journal of Viral Hepatitis 29:3, pages 178-188.
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Hyun Jin Jung, Hyun-Jin An, Mi-Gyeong Gwon, Hyemin Gu, Seongjae Bae, Sun-Jae Lee, Young-Ah Kim, Jaechan Leem & Kwan-Kyu Park. (2022) Anti-Fibrotic Effect of Synthetic Noncoding Oligodeoxynucleotide for Inhibiting mTOR and STAT3 via the Regulation of Autophagy in an Animal Model of Renal Injury. Molecules 27:3, pages 766.
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Yanji Zhu, Min Liu, Wenlong Xun, Keliang Li & Xiangji Niu. (2021) P2X7R antagonist protects against renal injury in mice with adriamycin nephropathy. Experimental and Therapeutic Medicine 23:2.
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Jiwon M. Lee, Andreas Kronbichler, Jae Il Shin & Jun Oh. (2020) Current understandings in treating children with steroid-resistant nephrotic syndrome. Pediatric Nephrology 36:4, pages 747-761.
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Dongjun Li, Denghui Wang & Shikai Yan. (2021) Exploration of underlying molecular mechanism of Lycii Cortex in Treating Type 2 Diabetes Mellitus Based on Network Pharmacology and Molecular Docking . E3S Web of Conferences 233, pages 02007.
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Qiuer Liang, Tianhao Liu, Tingting Guo, Wencong Tao, Xudong Chen, Weihao Chen, Liguo Chen & Ya Xiao. (2021) ATF4 promotes renal tubulointerstitial fibrosis by suppressing autophagy in diabetic nephropathy. Life Sciences 264, pages 118686.
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Elias A. T. Koch, Rola Nakhoul, Farid Nakhoul & Nakhoul Nakhoul. (2020) Autophagy in diabetic nephropathy: a review. International Urology and Nephrology 52:9, pages 1705-1712.
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Lili Zhang, Zhige Wen, Lin Han, Yujiao Zheng, Yu Wei, Xinmiao Wang, Qing Wang, Xinyi Fang, Linhua Zhao & Xiaolin Tong. (2020) Research Progress on the Pathological Mechanisms of Podocytes in Diabetic Nephropathy. Journal of Diabetes Research 2020, pages 1-15.
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A. O. Shpakov & E. V. Kaznacheyeva. (2020) Molecular Mechanisms of Apoptosis of Glomerular Podocytes in Diabetic Nephropathy. Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology 14:3, pages 205-222.
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Jiang Xu, Lin‐Qing Liu, Lin‐Lin Xu, Yan Xing & Shandong Ye. (2020) Metformin alleviates renal injury in diabetic rats by inducing Sirt1/FoxO1 autophagic signal axis. Clinical and Experimental Pharmacology and Physiology 47:4, pages 599-608.
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Dan-Yang Zhao, Dong-Dong Yu, Li Ren & Guo-Rong Bi. (2020) Ligustilide protects PC12 cells from oxygen-glucose deprivation/reoxygenation-induced apoptosis via the LKB1-AMPK-mTOR signaling pathway. Neural Regeneration Research 15:3, pages 473.
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