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Autoimmunity Volume 35, 2002 - Issue 6
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Research Article

Decreased IL-4 Producing CD4 + T Cells in Patients with Active Systemic Lupus Erythematosus-relation to IL-12R Expression

Kazunori Sugimoto Department of Rheumatology and Internal Medicine, Juntendo University School of Medicine, 2-1-1 Hongo Bunkyo-Ku, Tokyo 113-8421, Japan
,
Shinji Morimoto Department of Rheumatology and Internal Medicine, Juntendo University School of Medicine, 2-1-1 Hongo Bunkyo-Ku, Tokyo 113-8421, Japan
,
Hiroyuki Kaneko Department of Rheumatology and Internal Medicine, Juntendo University School of Medicine, 2-1-1 Hongo Bunkyo-Ku, Tokyo 113-8421, Japan
,
Kazuhisa Nozawa Department of Rheumatology and Internal Medicine, Juntendo University School of Medicine, 2-1-1 Hongo Bunkyo-Ku, Tokyo 113-8421, Japan
,
Yoshiaki Tokano Department of Rheumatology and Internal Medicine, Juntendo University School of Medicine, 2-1-1 Hongo Bunkyo-Ku, Tokyo 113-8421, Japan
,
Yoshinari Takasaki Department of Rheumatology and Internal Medicine, Juntendo University School of Medicine, 2-1-1 Hongo Bunkyo-Ku, Tokyo 113-8421, Japan
&
Hiroshi Hashimoto Department of Rheumatology and Internal Medicine, Juntendo University School of Medicine, 2-1-1 Hongo Bunkyo-Ku, Tokyo 113-8421, Japan
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Pages 381-387 | Published online: 07 Jul 2009

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Shinji Morimoto, Yoshiaki Tokano, Souichiro Nakano, Takashi Watanabe, Yoshihiro Tamayama, Akiko Mitsuo, Jun Suzuki, Hiroshi Kaneko, Iwao Sekigawa & Yoshinari Takasaki. (2009) Chemoattractant mechanism of Th1 cells in class III and IV lupus nephritis. Autoimmunity 42:2, pages 143-149.
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P. Enghard, D. Langnickel & G. Riemekasten. (2006) T cell cytokine imbalance towards production of IFN‐γ and IL‐10 in NZB/W F1 lupus‐prone mice is associated with autoantibody levels and nephritis. Scandinavian Journal of Rheumatology 35:3, pages 209-216.
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Articles from other publishers (18)

Daniele Accapezzato, Rosalba Caccavale, Maria Pia Paroli, Chiara Gioia, Bich Lien Nguyen, Luca Spadea & Marino Paroli. (2023) Advances in the Pathogenesis and Treatment of Systemic Lupus Erythematosus. International Journal of Molecular Sciences 24:7, pages 6578.
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Alin Laurentiu Tatu, Thomas Nadasdy, Anca Arbune, Valentin Chioncel, Carmen Bobeica, Elena Niculet, Alina Viorica Iancu, Caterina Dumitru, Valentin Tudor Popa, Nicolas Kluger, Victor Gabriel Clatici, Claudiu Ionut Vasile, Cristian Onisor & Alexandru Nechifor. (2022) Interrelationship and Sequencing of Interleukins4, 13, 31, and 33 – An Integrated Systematic Review: Dermatological and Multidisciplinary Perspectives. Journal of Inflammation Research Volume 15, pages 5163-5184.
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Jacqueline L. Paredes, Ruth Fernandez-Ruiz & Timothy B. Niewold. (2021) T Cells in Systemic Lupus Erythematosus. Rheumatic Disease Clinics of North America 47:3, pages 379-393.
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Bonnia Liu & Alberta Hoi. 2021. Pathogenesis of Systemic Lupus Erythematosus. Pathogenesis of Systemic Lupus Erythematosus 109 131 .
John D. Mountz, Hui-Chen Hsu & Andre Ballesteros-Tato. (2019) Dysregulation of T Follicular Helper Cells in Lupus. The Journal of Immunology 202:6, pages 1649-1658.
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Krisztina Vincze, Abigel Kolonics-Farkas, Aniko Bohacs & Veronika Müller. (2018) Peripheral CD4+ T-cell changes in connective tissue diseases. Cytokine & Growth Factor Reviews 43, pages 16-24.
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Chen Dong, Ting Fu, Juan Ji, Zhenyu Li & Zhifeng Gu. (2018) The role of interleukin-4 in rheumatic diseases. Clinical and Experimental Pharmacology and Physiology 45:8, pages 747-754.
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Manuel Rojas, Yhojan Rodríguez, Kelly Joan Leon, Yovana Pacheco, Yeny Acosta-Ampudia, Diana M. Monsalve, Carolina Ramírez-Santana & Juan-Manuel Anaya. (2018) Cytokines and Inflammatory Mediators in Systemic Lupus Erythematosus. EMJ Rheumatology, pages 83-92.
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Kunihiro Ichinose, Kazuhiko Arima, Masataka Umeda, Shoichi Fukui, Ayako Nishino, Yoshikazu Nakashima, Takahisa Suzuki, Yoshiro Horai, Tomohiro Koga, Shin-ya Kawashiri, Naoki Iwamoto, Keita Fujikawa, Toshiyuki Aramaki, Mami Tamai, Hideki Nakamura, Shuntaro Sato, Tomoki Origuchi & Atsushi Kawakami. (2016) Predictors of clinical outcomes in patients with neuropsychiatric systemic lupus erythematosus. Cytokine 79, pages 31-37.
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Yinglu Feng, Chunbin Wang, Silu Cheng, Xiaorong Wang, Xianze Meng, Lujia Li, Juan Du, Qun Liu, Yuyu Guo, Yongbin Meng, Binbin Cheng & Changquan Ling. (2015) Ginsenoside Rh1 Improves the Effect of Dexamethasone on Autoantibodies Production and Lymphoproliferation in MRL/lpr Mice. Evidence-Based Complementary and Alternative Medicine 2015, pages 1-8.
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Frank R. Brennan. 2014. Handbook of Therapeutic Antibodies. Handbook of Therapeutic Antibodies 969 1078 .
Enass A. Elewa, Omyma Zakaria, Enas I. Mohamed & Ghada Boghdadi. (2014) The role of interleukins 4, 17 and interferon gamma as biomarkers in patients with Systemic Lupus Erythematosus and their correlation with disease activity. The Egyptian Rheumatologist 36:1, pages 21-27.
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H-H. Yu, P-H. Liu, Y-C. Lin, WJ Chen, J-H. Lee, L-C. Wang, Y-H. Yang & B-L. Chiang. (2010) Interleukin 4 and STAT6 gene polymorphisms are associated with systemic lupus erythematosus in Chinese patients. Lupus 19:10, pages 1219-1228.
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Naomi Matsuyama, Shinji Morimoto, Yoshiaki Tokano, Hirofumi Amano, Kazuhisa Nozawa, Hiroshi Isonuma, Hiroshi Hashimoto & Yoshinari Takasaki. (2010) The Long-Term Prognosis of Lupus Nephritis Patients Treated with Intravenous Cyclophosphamide. Internal Medicine 49:9, pages 823-828.
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ANNE DAVIDSON & BETTY DIAMOND. 2006. The Autoimmune Diseases. The Autoimmune Diseases 25 36 .
HIROSHI HASHIMOTO. (2005) Learning of clinical medicine from inflammatory connectie tissue diseases膠原病から学ぶ臨床医学. Juntendo Medical Journal 51:2, pages 123-135.
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T. Biro, Z. Griger, E. Kiss, H. Papp, M. Aleksza, I. Kovacs, M. Zeher, E. Bodolay, T. Csepany, K. Szucs, P. Gergely, L. Kovacs, G. Szegedi & S. Sipka. (2004) Abnormal Cell-Specific Expressions of Certain Protein Kinase C Isoenzymes in Peripheral Mononuclear Cells of Patients with Systemic Lupus Erythematosus: Effect of Corticosteroid Application. Scandinavian Journal of Immunology 60:4, pages 421-428.
Crossref
M MATSUI, S ARAYA, H-Y WANG, N ONAI, K MATSUSHIMA & T SAIDA. (2003) Circulating lymphocyte subsets linked to intracellular cytokine profiles in normal humans. Clinical and Experimental Immunology 134:2, pages 225-231.
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