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Original Article

The Contribution of Immune Regulatory and Thyroid Specific Genes to the Etiology of Graves' and Hashimoto's Diseases

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Pages 367-379 | Published online: 07 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Xiaokun Shen, Xingqiang Yan, Bojian Xie, Dong Xu, Kuifeng Wang, Jiansheng Zhu, Jichen Li, Xiaohua Zhang & Feilin Cao. (2015) Genetic variants of interleukin-4 gene in autoimmune thyroid diseases: An updated meta-analysis. Autoimmunity 48:2, pages 129-135.
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Artur Bossowski, Hanna Borysewicz-Sańczyk, Natalia Wawrusiewicz-Kurylonek, Aneta Zasim, Mieczysław Szalecki, Beata Wikiera, Ewa Barg, Małgorzata Myśliwiec, Anna Kucharska, Anna Bossowska, Joanna Gościk, Katarzyna Ziora, Maria Górska & Adam Krętowski. (2014) Analysis of chosen polymorphisms in FoxP3 gene in children and adolescents with autoimmune thyroid diseases. Autoimmunity 47:6, pages 395-400.
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Ines Zaaber, Souhir Mestiri, Hela Marmouch, Silvia Mahjoub, Nabil Abid, Mohsen Hassine, Besma Bel Hadj Jrad-Tensaout & Khaled Said. (2014) Polymorphisms in TSHR and IL1RN genes and the risk and prognosis of Hashimoto’s thyroiditis. Autoimmunity 47:2, pages 113-118.
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Yoshiyuki Ban, Teruaki Tozaki & Matsuo Taniyama. (2013) The replication of the association of the rs9355610 within 6p27 with Graves’ disease. Autoimmunity 46:6, pages 395-398.
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Agata Jabrocka-Hybel, Anna Skalniak, Jakub Piątkowski, Dorota Pach & Alicja Hubalewska-Dydejczyk. (2013) How Far Are We from Understanding the Genetic Basis of Hashimoto's Thyroiditis?. International Reviews of Immunology 32:3, pages 337-354.
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Ni Yan, Yong-Liang Yu, Jing Yang, Qiu Qin, Yuan-Feng Zhu, Xuan Wang, Rong-Hua Song & Jin-An Zhang. (2012) Association of interleukin-17A and -17F gene single-nucleotide polymorphisms with autoimmune thyroid diseases. Autoimmunity 45:7, pages 533-539.
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Yoshiyuki Ban, Teruaki Tozaki, Matsuo Taniyama, Yasuko Nakano, Kei-Ichiro Yoneyama, Yoshio Ban & Tsutomu Hirano. (2009) Association studies of the IL-23R gene in autoimmune thyroid disease in the Japanese population. Autoimmunity 42:2, pages 126-130.
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Manuela Dittmar, Adam Kaczmarczyk, Christian Bischofs & George J. Kahaly. (2009) The Proinflammatory Cytokine TNF-α -308 AA Genotype is Associated with Polyglandular Autoimmunity. Immunological Investigations 38:3-4, pages 255-267.
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María-Carolina Páez, María-Julieta González, Norma C. Serrano, Yehuda Shoenfeld & Juan-Manuel Anaya. (2007) Physiological and pathological implications of laminins: From the gene to the protein. Autoimmunity 40:2, pages 83-94.
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Yuan Li, Chenxu Zhao, Keli Zhao, Nan Yu, Yan Li, Yang Yu, Yang Zhang, Zhijing Song, Youyuan Huang, Guizhi Lu, Ying Gao, Junqing Zhang & Xiaohui Guo. (2021) Glycosylation of Anti-Thyroglobulin IgG1 and IgG4 Subclasses in Thyroid Diseases. European Thyroid Journal 10:2, pages 114-124.
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Warda Kherrour, Dean Kalicanin, Luka Brčić, Leila Hambaba, Mouloud Yahia, Souheyla Benbia & Vesna Boraska Perica. (2020) Genotype association of IP6K3 gene with Hashimoto’s thyroiditis in Algerian population (Aures region). Egyptian Journal of Medical Human Genetics 21:1.
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Liyan Li, Shudong Liu & Junxia Yu. (2020) Autoimmune thyroid disease and type 1 diabetes mellitus: same pathogenesis; new perspective?. Therapeutic Advances in Endocrinology and Metabolism 11, pages 204201882095832.
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Xue He, Chuhui Xiong, Aihua Liu, Wei Zhao, Xinghai Xia, Shiqiao Peng, Chenyan Li, Mi Zhou, Yushu Li, Xiaoguang Shi, Zhongyan Shan & Weiping Teng. (2017) Phagocytosis Deficiency of Macrophages in NOD.H-2h4 Mice Accelerates the Severity of Iodine-Induced Autoimmune Thyroiditis. Biological Trace Element Research 184:1, pages 196-205.
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Edyta Pawlak-Adamska, Irena Frydecka, Marek Bolanowski, Anna Tomkiewicz, Anna Jonkisz, Lidia Karabon, Anna Partyka, Oskar Nowak, Marek Szalinski & Jacek Daroszewski. (2016) CD28/CTLA-4/ICOS haplotypes confers susceptibility to Graves’ disease and modulates clinical phenotype of disease. Endocrine 55:1, pages 186-199.
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N. E. Bufalo, R. B. dos Santos, M. A. Marcello, R. P. Piai, R. Secolin, J. H. Romaldini & L. S. Ward. (2014) TSHR intronic polymorphisms (rs179247 and rs12885526) and their role in the susceptibility of the Brazilian population to Graves’ disease and Graves’ ophthalmopathy. Journal of Endocrinological Investigation 38:5, pages 555-561.
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Ni Yan, Shuai Meng, Jiaozhen Zhou, Jian Xu, Fatuma Muhali, Wenjuan Jiang, Liangfeng Shi, Xiaohong Shi & Jinan Zhang. (2014) Association between STAT4 Gene Polymorphisms and Autoimmune Thyroid Diseases in a Chinese Population. International Journal of Molecular Sciences 15:7, pages 12280-12293.
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A Popławska-Kita, M Szelachowska, A Modzelewska, K Siewko, J Dzięcioł, PA Klimiuk & M Górska. (2013) Endothelial dysfunction in Graves' disease. Advances in Medical Sciences 58:1, pages 31-37.
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Syed A. Morshed, Rauf Latif & Terry F. Davies. (2012) Delineating the autoimmune mechanisms in Graves’ disease. Immunologic Research 54:1-3, pages 191-203.
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Yoshiyuki Ban, Teruaki Tozaki, Matsuo Taniyama, Luce Skrabanek, Yasuko Nakano, Yoshio Ban & Tsutomu Hirano. (2012) Multiple SNPs in Intron 41 of Thyroglobulin Gene Are Associated with Autoimmune Thyroid Disease in the Japanese Population. PLoS ONE 7:5, pages e37501.
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Akira Kawashima, Kazunari Tanigawa, Takeshi Akama, Aya Yoshihara, Norihisa Ishii & Koichi Suzuki. (2011) Innate Immune Activation and Thyroid Autoimmunity. The Journal of Clinical Endocrinology & Metabolism 96:12, pages 3661-3671.
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Yoshiyuki BanTeruaki TozakiMatsuo TaniyamaYasuko NakanoYoshihisa BanYoshio BanTsutomu Hirano. (2010) Association of the Protein Tyrosine Phosphatase Nonreceptor 22 Haplotypes with Autoimmune Thyroid Disease in the Japanese Population. Thyroid 20:8, pages 893-899.
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Radovan Bílek & Václav Zamrazil. 2009. Comprehensive Handbook of Iodine. Comprehensive Handbook of Iodine 55 64 .
Su He WangJames R. BakerJr.Jr.. (2007) The Role of Apoptosis in Thyroid Autoimmunity. Thyroid 17:10, pages 975-979.
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Yaron Tomer, Francesca Menconi, Terry F. Davies, Giuseppe Barbesino, Roberto Rocchi, Aldo Pinchera, Erlinda Concepcion & David A. Greenberg. (2007) Dissecting genetic heterogeneity in autoimmune thyroid diseases by subset analysis. Journal of Autoimmunity 29:2-3, pages 69-77.
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Yoshiyuki Ban, Teruaki Tozaki, Takashi Tobe, Yoshio Ban, Eric M. Jacobson, Erlinda S. Concepcion & Yaron Tomer. (2007) The regulatory T cell gene FOXP3 and genetic susceptibility to thyroid autoimmunity: An association analysis in Caucasian and Japanese cohorts. Journal of Autoimmunity 28:4, pages 201-207.
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Ernst G. Eising, Walter Jentzen, Lutz Freudenberg & Andreas Bockisch. (2007) Value of Low Levels of Anti-TPO Antibodies in Patients With Suspicion of Hashimoto Thyroiditis. The Endocrinologist 17:2, pages 83-84.
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Susan E. HodgeYoshiyuki BanLisa J. StrugDavid A. GreenbergTerry F. DaviesErlinda S. ConcepcionRonald VillanuevaYaron Tomer. (2006) Possible Interaction Between HLA-DR β 1 and Thyroglobulin Variants in Graves' Disease . Thyroid 16:4, pages 351-355.
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Yu Yang, Sun Lingling, Jin Ying, Li Yushu, Shan Zhongyan, Huang Wei & Teng Weiping. (2005) Association study between the IL4, IL13, IRF1 and UGRP1 genes in chromosomal 5q31 region and Chinese Graves’ disease. Journal of Human Genetics 50:11, pages 574-582.
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Yoshiyuki BanTeruaki TozakiMatsuo TaniyamaMotowo TomitaYoshio Ban. (2005) The Codon 620 Single Nucleotide Polymorphism of the Protein Tyrosine Phosphatase-22 Gene Does not Contribute to Autoimmune Thyroid Disease Susceptibility in the Japanese. Thyroid 15:10, pages 1115-1118.
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Donato Alarcón-Segovia, Marta E. Alarcón-Riquelme, Mario H. Cardiel, Francisco Caeiro, Loreto Massardo, Antonio R. Villa & Bernardo A. Pons-Estel. (2005) Familial aggregation of systemic lupus erythematosus, rheumatoid arthritis, and other autoimmune diseases in 1,177 lupus patients from the GLADEL cohort. Arthritis & Rheumatism 52:4, pages 1138-1147.
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Manuela DittmarGeorge J. Kahaly. (2005) Immunoregulatory and Susceptibility Genes in Thyroid and Polyglandular Autoimmunity. Thyroid 15:3, pages 239-250.
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Manorama Swain, Truptirekha Swain & Binoy Kumar Mohanty. (2005) Autoimmune thyroid disorders—An update. Indian Journal of Clinical Biochemistry 20:1, pages 9-17.
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Nicole M. Parish & Anne Cooke. (2004) Mechanisms of autoimmune thyroid disease. Drug Discovery Today: Disease Mechanisms 1:3, pages 337-344.
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Donato Alarcón-Segovia. (2004) Shared autoimmunity: The time has come. Current Rheumatology Reports 6:3, pages 171-174.
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