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Autoimmunity Volume 36, 2003 - Issue 6-7: Current Perspectives On Thyroid Autoimmune Diseases
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Original Article

Thyrotropin Receptor Autoantibodies (TSHRAbs): Epitopes, Origins and Clinical Significance

Leonard D. Kohna Edison Biotechnology Institute and Department of Biomedical Sciences, Ohio University School of Osteopathic Medicine, Ohio University, 45701, Athens, OH, USA
&
Norikazu Hariia Edison Biotechnology Institute and Department of Biomedical Sciences, Ohio University School of Osteopathic Medicine, Ohio University, 45701, Athens, OH, USACorrespondence[email protected]; [email protected]
Pages 331-337 | Published online: 07 Jul 2009

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Urszula Piotrowska, Grażyna Adler & Jacek Kilianski. (2004) Residues 34–39 in the Thyrotropin Receptor are not the Target of Autoantibodies from Sera of Patients with Graves' Disease. Endocrine Research 30:3, pages 431-441.
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Articles from other publishers (28)

Wei Lu, Zhengyuan Wang, Zhuo Sun, Zehuan Shi, Qi Song, Xueying Cui, Liping Shen, Mengying Qu, Shupeng Mai & Jiajie Zang. (2022) The Interactive Effects of Severe Vitamin D Deficiency and Iodine Nutrition Status on the Risk of Thyroid Disorder in Pregnant Women. Nutrients 14:21, pages 4484.
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Rusan Ali Catar, Oskar Wischnewski, Lei Chen, Harald Heidecke, Claudia Rutz, Ralf Schülein, Duska Dragun, Aurélie Philippe & Angelika Kusch. (2022) Non-HLA antibodies targeting angiotensin II Type 1 receptor and endothelin-1 Type A receptors induce endothelial injury via β2-arrestin link to mTOR pathway. Kidney International 101:3, pages 498-509.
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Yu-De Chu & Chau-Ting Yeh. (2020) The Molecular Function and Clinical Role of Thyroid Stimulating Hormone Receptor in Cancer Cells. Cells 9:7, pages 1730.
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Minjae KimSungwon YangJinhwan ParkHwa LeeSehyun Baek. (2018) Risk Factors for Structural Changes in Meibomian Gland in Thyroid Eye Disease. Journal of the Korean Ophthalmological Society 59:7, pages 599.
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M. Tariq Bhatti & Jonathan J. Dutton. (2014) Thyroid Eye Disease. Journal of Neuro-Ophthalmology 34:2, pages 186-197.
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Scott A. Rivkees. 2014. Pediatric Endocrinology. Pediatric Endocrinology 444 470.e1 .
Gunnar Kleinau & Heike Biebermann. 2014. Pharmacology & Therapeutics of Constitutively Active Receptors. Pharmacology & Therapeutics of Constitutively Active Receptors 81 119 .
Gunnar Kleinau, Susanne Neumann, Annette Grüters, Heiko Krude & Heike Biebermann. (2013) Novel Insights on Thyroid-Stimulating Hormone Receptor Signal Transduction. Endocrine Reviews 34:5, pages 691-724.
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Toyoshi Endo & Teturo Kobayashi. (2013) Immunization of mice with a newly identified thyroid-stimulating hormone receptor splice variant induces Graves'-like disease. Journal of Autoimmunity 43, pages 18-25.
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Edvina Gregoric, Jurji Avramovic Gregoric, Fabrizio Guarneri & Salvatore Benvenga. (2010) Injections of Clostridium botulinum neurotoxin A may cause thyroid complications in predisposed persons based on molecular mimicry with thyroid autoantigens. Endocrine 39:1, pages 41-47.
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Jae Ryun KimHye Bin YimSung Kun Chung. (2011) Risk Factors for Dry Eye in Thyroid-Associated Ophthalmopathy. Journal of the Korean Ophthalmological Society 52:7, pages 771.
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Simon D. Lytton & George J. Kahaly. (2010) Bioassays for TSH-receptor autoantibodies: An update. Autoimmunity Reviews 10:2, pages 116-122.
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S D Lytton, Y Li, P D Olivo, L D Kohn & G J Kahaly. (2010) Novel chimeric thyroid-stimulating hormone-receptor bioassay for thyroid-stimulating immunoglobulins. Clinical and Experimental Immunology 162:3, pages 438-446.
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Keiichi KamijoHiroshi MurayamaTakahiro UzuKazuyoshi TogashiGeorge J. Kahaly. (2010) A Novel Bioreporter Assay for Thyrotropin Receptor Antibodies Using a Chimeric Thyrotropin Receptor (Mc4) Is More Useful in Differentiation of Graves' Disease from Painless Thyroiditis Than Conventional Thyrotropin-Stimulating Antibody Assay Using Porcine Thyroid Cells. Thyroid 20:8, pages 851-856.
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Michael W Jackson, Nicolas J Spencer, Joanne H Reed, Anthony J F Smith & Tom P Gordon. (2009) Potentiation of a functional autoantibody in narcolepsy by a cholinesterase inhibitor. Laboratory Investigation 89:12, pages 1332-1339.
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Hidetaka Fukushima, Hideaki Matsuo, Koji Imamura, Kazuhiko Morino, Katsuzumi Okumura, Kanta Tsumoto & Tetsuro Yoshimura. (2009) Diagnosis and discrimination of autoimmune Graves' disease and Hashimoto's disease using thyroid-stimulating hormone receptor-containing recombinant proteoliposomes. Journal of Bioscience and Bioengineering 108:6, pages 551-556.
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M J Leandro & I De La Torre. (2009) Translational Mini-Review Series on B Cell-Directed Therapies: The pathogenic role of B cells in autoantibody-associated autoimmune diseases – lessons from B cell-depletion therapy. Clinical and Experimental Immunology 157:2, pages 191-197.
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Suzanne Myers Adler & Kenneth D. Burman. 2009. Clinical Management of Thyroid Disease. Clinical Management of Thyroid Disease 241 253 .
Stéphanie Gaillard & Fredric E. Wondisford. 2009. Clinical Management of Thyroid Disease. Clinical Management of Thyroid Disease 81 101 .
Katherine A. McLaughlin & Kai W. Wucherpfennig. 2008. Advances in Immunology Volume 98. Advances in Immunology Volume 98 121 149 .
Joop P van de Merwe. (2007) Interstitial cystitis and systemic autoimmune diseases. Nature Clinical Practice Urology 4:9, pages 484-491.
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Melvin Khee-Shing Leow. (2007) A mathematical model of pituitary–thyroid interaction to provide an insight into the nature of the thyrotropin–thyroid hormone relationship. Journal of Theoretical Biology 248:2, pages 275-287.
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Jane SandersRicardo Núñez MiguelJane BoltonAnshu BhardwajaPaul SandersNobuhiro NakatakeMichele EvansJadwiga FurmaniakBernard Rees Smith. (2007) Molecular Interactions between the TSH Receptor and a Thyroid-Stimulating Monoclonal Autoantibody. Thyroid 17:8, pages 699-706.
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Jane SandersJane BoltonPaul SandersJennifer JeffreysNobuhiro NakatakeTonya RichardsMichele EvansAngela KiddieSara SummerhayesEmma RobertsRicardo Núñez MiguelJadwiga FurmaniakBernard Rees Smith. (2006) Effects of TSH Receptor Mutations on Binding and Biological Activity of Monoclonal Antibodies and TSH. Thyroid 16:12, pages 1195-1206.
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Heiko Andresen, Kim Zarse, Carsten Grötzinger, Jörg-M. Hollidt, Eva Ehrentreich-Förster, Frank F. Bier & Oliver J. Kreuzer. (2006) Development of peptide microarrays for epitope mapping of antibodies against the human TSH receptor. Journal of Immunological Methods 315:1-2, pages 11-18.
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Salvatore BenvengaLibero SantarpiaFrancesco TrimarchiFabrizio Guarneri. (2006) Human Thyroid Autoantigens and Proteins of Yersinia and Borrelia Share Amino Acid Sequence Homology That Includes Binding Motifs to HLA-DR Molecules and T-Cell Receptor . Thyroid 16:3, pages 225-236.
Crossref
Su-Chin Ho, Sui-Sin Goh, Qing Su & Daphne Hsu-Chin Khoo. (2005) Cysteine 390 mutation of the TSH receptor modulates its ectodomain as an inverse agonist on the serpentine domain with decrease in basal constitutive activity. Molecular and Cellular Endocrinology 245:1-2, pages 158-168.
Crossref
Michael T. Stang & John H. Yim. 2005. Measuring Immunity. Measuring Immunity 543 559 .

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