316
Views
58
CrossRef citations to date
0
Altmetric
Original Article

Autoantibodies to citrullinated proteins: ACPA

, , , &
Pages 17-24 | Received 28 Jul 2004, Accepted 28 Aug 2004, Published online: 07 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Liliana Elena D'agostino, Fernando Ventimiglia, Juan Antonio Verna, Amelia De La Colina, Yanina Aguirre, Alfredo Arturi & Alberto Capparelli. (2013) Correlation between DAS-28 and neopterin as a biochemical marker of immune system activation in early rheumatoid arthritis. Autoimmunity 46:1, pages 44-49.
Read now
Zoltán Szekanecz & Gabriella Lakos. (2008) Rheumatoid arthritis diagnosis with antimutated citrullinated vimentin ELISA by Orgentec Diagnostika. Expert Opinion on Medical Diagnostics 2:9, pages 1083-1090.
Read now
Amalia Raptopoulou, Prodromos Sidiropoulos, Maria Katsouraki & Dimitrios T. Boumpas. (2007) Anti-Citrulline Antibodies in the Diagnosis and Prognosis of Rheumatoid Arthritis: Evolving Concepts. Critical Reviews in Clinical Laboratory Sciences 44:4, pages 339-363.
Read now

Articles from other publishers (55)

Wanitcha Gumtorntip, Nuntana Kasitanon, Worawit Louthrenoo, Nipon Chattipakorn & Siriporn C. Chattipakorn. (2023) Potential roles of air pollutants on the induction and aggravation of rheumatoid arthritis: From cell to bedside studies. Environmental Pollution 334, pages 122181.
Crossref
James D. GuestMargot Kelly-HedrickTheresa WilliamsonChristine ParkDaniyal Mansoor AliAhilan SivaganesanChris J. NealCharles H. TatorMichael G. Fehlings. (2023) Development of a Systems Medicine Approach to Spinal Cord Injury. Journal of Neurotrauma.
Crossref
Tuğba AKTAN KÖŞKER, İsmail DOĞAN, Orhan KÜÇÜKŞAHİN & Şükran ERTEN. (2022) Prevalence and clinical significance of serum anti-cyclic citrullinated peptide antibodies in primary Sjögren's syndrome. The European Research Journal 8:3, pages 347-353.
Crossref
Jean-Luc Davignon, Bernard Combe & Alain Cantagrel. (2021) Cytomegalovirus infection: friend or foe in rheumatoid arthritis?. Arthritis Research & Therapy 23:1.
Crossref
Chang-Youh Tsai, Song-Chou Hsieh, Chih-Wei Liu, Cheng-Hsun Lu, Hsien-Tzung Liao, Ming-Han Chen, Ko-Jen Li, Cheng-Han Wu, Cheih-Yu Shen, Yu-Min Kuo & Chia-Li Yu. (2021) The Expression of Non-Coding RNAs and Their Target Molecules in Rheumatoid Arthritis: A Molecular Basis for Rheumatoid Pathogenesis and Its Potential Clinical Applications. International Journal of Molecular Sciences 22:11, pages 5689.
Crossref
Linda M. Slot, Rochelle D. Vergroesen, Priscilla F. Kerkman, Ellen Staudinger, Sanne Reijm, Hugo J. van Dooren, Ellen I. H. van der Voort, Tom W. J. Huizinga, René E. M. Toes & Hans U. Scherer. (2021) Light chain skewing in autoantibodies and B-cell receptors of the citrullinated antigen-binding B-cell response in rheumatoid arthritis. PLOS ONE 16:3, pages e0247847.
Crossref
G Halpert, M Halperin Sheinfeld, L Monteran, K Sharif, A Volkov, R Nadler, A Schlesinger, I Barshak, Y Kalechman, M Blank, Y Shoenfeld & H Amital. (2021) The tellurium-based immunomodulator, AS101 ameliorates adjuvant-induced arthritis in rats. Clinical and Experimental Immunology 203:3, pages 375-384.
Crossref
Kristine Germar, Cynthia M. Fehres, Hans U. Scherer, Nathalie Uden, Sabrina Pollastro, Nataliya Yeremenko, Monika Hansson, Priscilla F. Kerkman, Ellen I. H. Voort, Evan Reed, Hanna Maassen, Mark J. Kwakkenbos, Arjen Q. Bakker, Lars Klareskog, Vivianne Malmström, Niek Vries, René E. M. Toes, Karin Lundberg, Hergen Spits & Dominique L. Baeten. (2019) Generation and Characterization of Anti–Citrullinated Protein Antibody–Producing B Cell Clones From Rheumatoid Arthritis Patients. Arthritis & Rheumatology 71:3, pages 340-350.
Crossref
Carlo Perricone, Mathilde Versini, Dana Ben-Ami, Smadar Gertel, Abdulla Watad, Michael J. Segel, Fulvia Ceccarelli, Fabrizio Conti, Luca Cantarini, Dimitrios P. Bogdanos, Alessandro Antonelli, Howard Amital, Guido Valesini & Yehuda Shoenfeld. 2019. Mosaic of Autoimmunity. Mosaic of Autoimmunity 383 415 .
João Pedro Gomes, Abdulla Watad & Yehuda Shoenfeld. (2018) Nicotine and autoimmunity: The lotus’ flower in tobacco. Pharmacological Research 128, pages 101-109.
Crossref
Udhayakumar Gopal & Salvatore V. Pizzo. 2018. Cell Surface GRP78, a New Paradigm in Signal Transduction Biology. Cell Surface GRP78, a New Paradigm in Signal Transduction Biology 9 40 .
Stefano Alivernini, Mauro Galeazzi, Hagit Peleg, Barbara Tolusso, Elisa Gremese, Gianfranco Ferraccioli & Yaakov Naparstek. (2017) Is ACPA positivity the main driver for rheumatoid arthritis treatment? Pros and cons. Autoimmunity Reviews 16:11, pages 1096-1102.
Crossref
Nicole Trier & Gunnar Houen. (2017) Epitope Specificity of Anti-Citrullinated Protein Antibodies. Antibodies 6:1, pages 5.
Crossref
Camille P Figueiredo, Holger Bang, Jayme Fogagnolo Cobra, Matthias Englbrecht, Axel J Hueber, Judith Haschka, Bernhard Manger, Arnd Kleyer, Michaela Reiser, Stephanie Finzel, Hans-Peter Tony, Stefan Kleinert, Joerg Wendler, Florian Schuch, Monika Ronneberger, Martin Feuchtenberger, Martin Fleck, Karin Manger, Wolfgang Ochs, Matthias Schmitt-Haendle, Hanns-Martin Lorenz, Hubert Nuesslein, Rieke Alten, Joerg Henes, Klaus Krueger, Jürgen Rech & Georg Schett. (2017) Antimodified protein antibody response pattern influences the risk for disease relapse in patients with rheumatoid arthritis tapering disease modifying antirheumatic drugs. Annals of the Rheumatic Diseases 76:2, pages 399-407.
Crossref
F. Buket Ü. Basmanav, Laura Cau, Aylar Tafazzoli, Marie-Claire Méchin, Sabrina Wolf, Maria Teresa Romano, Frederic Valentin, Henning Wiegmann, Anne Huchenq, Rima Kandil, Natalie Garcia Bartels, Arzu Kilic, Susannah George, Damian J. Ralser, Stefan Bergner, David J.P. Ferguson, Ana-Maria Oprisoreanu, Maria Wehner, Holger Thiele, Janine Altmüller, Peter Nürnberg, Daniel Swan, Darren Houniet, Aline Büchner, Lisa Weibel, Nicola Wagner, Ramon Grimalt, Anette Bygum, Guy Serre, Ulrike Blume-Peytavi, Eli Sprecher, Susanne Schoch, Vinzenz Oji, Henning Hamm, Paul Farrant, Michel Simon & Regina C. Betz. (2016) Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome. The American Journal of Human Genetics 99:6, pages 1292-1304.
Crossref
Gaëlle Wambiekele Kiyeko, Eric Hatterer, Suzanne Herren, Irene Di Ceglie, Peter L. van Lent, Walter Reith, Marie Kosco-Vilbois, Walter Ferlin & Limin Shang. (2016) Spatiotemporal expression of endogenous TLR4 ligands leads to inflammation and bone erosion in mouse collagen-induced arthritis. European Journal of Immunology 46:11, pages 2629-2638.
Crossref
Carlo Perricone, Mathilde Versini, Dana Ben-Ami, Smadar Gertel, Abdulla Watad, Michael J. Segel, Fulvia Ceccarelli, Fabrizio Conti, Luca Cantarini, Dimitrios P. Bogdanos, Alessandro Antonelli, Howard Amital, Guido Valesini & Yehuda Shoenfeld. (2016) Smoke and autoimmunity: The fire behind the disease. Autoimmunity Reviews 15:4, pages 354-374.
Crossref
Jonathan Akikusa & Sharon Choo. 2016. Textbook of Pediatric Rheumatology. Textbook of Pediatric Rheumatology 117 128.e6 .
Joachim Høg Mortensen, Line Elbjerg Godskesen, Michael Dam Jensen, Wouter Tobias Van Haaften, Lone Gabriels Klinge, Peter Olinga, Gerard Dijkstra, Jens Kjeldsen, Morten Asser Karsdal, Anne-Christine Bay-Jensen & Aleksander Krag. (2015) Fragments of Citrullinated and MMP-degraded Vimentin and MMP-degraded Type III Collagen Are Novel Serological Biomarkers to Differentiate Crohn’s Disease from Ulcerative Colitis. Journal of Crohn's and Colitis 9:10, pages 863-872.
Crossref
Smadar Gertel, Guy Serre, Yehuda Shoenfeld & Howard Amital. (2015) Immune Tolerance Induction with Multiepitope Peptide Derived from Citrullinated Autoantigens Attenuates Arthritis Manifestations in Adjuvant Arthritis Rats. The Journal of Immunology 194:12, pages 5674-5680.
Crossref
J. Charles Jennette & Ronald J. Falk. (2015) ANCAs Are Also Antimonocyte Cytoplasmic Autoantibodies. Clinical Journal of the American Society of Nephrology 10:1, pages 4-6.
Crossref
Ladislav Šenolt, Walter Grassi & Peter Szodoray. (2014) Laboratory biomarkers or imaging in the diagnostics of rheumatoid arthritis?. BMC Medicine 12:1.
Crossref
Paola de Pablo, Thomas Dietrich, Iain L C Chapple, Michael Milward, Muslima Chowdhury, Peter J Charles, Christopher D Buckley & Patrick J Venables. (2014) The autoantibody repertoire in periodontitis: a role in the induction of autoimmunity to citrullinated proteins in rheumatoid arthritis?. Annals of the Rheumatic Diseases 73:3, pages 580-586.
Crossref
Sima Sh. Farid, Gholamreza Azizi & Abbas Mirshafiey. (2013) Anti-citrullinated protein antibodies and their clinical utility in rheumatoid arthritis. International Journal of Rheumatic Diseases 16:4, pages 379-386.
Crossref
Fruzsina Babos, Eszter Szarka, György Nagy, Zsuzsa Majer, Gabriella Sármay, Anna Magyar & Ferenc Hudecz. (2013) Role of N - or C -Terminal Biotinylation in Autoantibody Recognition of Citrullin Containing Filaggrin Epitope Peptides in Rheumatoid Arthritis . Bioconjugate Chemistry 24:5, pages 817-827.
Crossref
J.-L. Davignon, M. Hayder, M. Baron, J.-F. Boyer, A. Constantin, F. Apparailly, R. Poupot & A. Cantagrel. (2012) Targeting monocytes/macrophages in the treatment of rheumatoid arthritis. Rheumatology 52:4, pages 590-598.
Crossref
Petra Misják, Szilvia Bősze, Kata Horváti, Mária Pásztói, Krisztina Pálóczi, Marianna C. Holub, Ferenc Szakács, Borbála Aradi, Bence György, Tamás G. Szabó, György Nagy, Tibor T. Glant, Katalin Mikecz, András Falus & Edit I. Buzás. (2013) The role of citrullination of an immunodominant proteoglycan (PG) aggrecan T cell epitope in BALB/c mice with PG-induced arthritis. Immunology Letters 152:1, pages 25-31.
Crossref
Tineke Cantaert, Christine Teitsma, Paul P. Tak & Dominique Baeten. (2013) Presence and Role of Anti–Citrullinated Protein Antibodies in Experimental Arthritis Models. Arthritis & Rheumatism 65:4, pages 939-948.
Crossref
XIAOTIAN CHANG, YAN ZHAO, YUEJIAN WANG, YU CHEN & XINFENG YAN. (2013) Screening Citrullinated Proteins in Synovial Tissues of Rheumatoid Arthritis Using 2-dimensional Western Blotting. The Journal of Rheumatology 40:3, pages 219-227.
Crossref
Anders J. Svendsen, Jacob V. Hjelmborg, Kirsten O. Kyvik, Gunnar Houen, Christian Nielsen, Axel Skytthe & Peter Junker. (2013) The impact of genes on the occurrence of autoantibodies in rheumatoid arthritis. A study on disease discordant twin pairs. Journal of Autoimmunity 41, pages 120-125.
Crossref
Peter Taylor, Juliane Gartemann, Jeanie Hsieh & James Creeden. (2011) A Systematic Review of Serum Biomarkers Anti-Cyclic Citrullinated Peptide and Rheumatoid Factor as Tests for Rheumatoid Arthritis. Autoimmune Diseases 2011, pages 1-18.
Crossref
Marie-Claire Méchin, Rachida Nachat, Fanny Coudane, Véronique Adoue, Jacques Arnaud, Guy Serre & Michel Simon. (2011) La désimination ou citrullination. médecine/sciences 27:1, pages 49-54.
Crossref
Julie A Di Paolo, Tao Huang, Mercedesz Balazs, James Barbosa, Kai H Barck, Brandon J Bravo, Richard A D Carano, James Darrow, Douglas R Davies, Laura E DeForge, Lauri Diehl, Ronald Ferrando, Steven L Gallion, Anthony M Giannetti, Peter Gribling, Vincent Hurez, Sarah G Hymowitz, Randall Jones, Jeffrey E Kropf, Wyne P Lee, Patricia M Maciejewski, Scott A Mitchell, Hong Rong, Bart L Staker, J Andrew Whitney, Sherry Yeh, Wendy B Young, Christine Yu, Juan Zhang, Karin Reif & Kevin S Currie. (2010) Specific Btk inhibition suppresses B cell– and myeloid cell–mediated arthritis. Nature Chemical Biology 7:1, pages 41-50.
Crossref
Günter Steiner & Markus Hoffmann. 2011. Rheumatology. Rheumatology 887 895.e2 .
Lie Ying Fan, Ming Zong, Qiang Wang, Lin Yang, Li Shan Sun, Qin Ye, Yuan Yuan Ding & Jian Wei Ma. (2010) Diagnostic value of glucose-6-phosphate isomerase in rheumatoid arthritis. Clinica Chimica Acta 411:23-24, pages 2049-2053.
Crossref
Markus Hoffmann, Silvia Hayer & Guenter Steiner. (2009) Immmunopathogenesis of Rheumatoid Arthritis. Annals of the New York Academy of Sciences 1173:1, pages 391-400.
Crossref
Nobuo Okumura, Ayumi Haneishi & Fumiko Terasawa. (2009) Citrullinated fibrinogen shows defects in FPA and FPB release and fibrin polymerization catalyzed by thrombin. Clinica Chimica Acta 401:1-2, pages 119-123.
Crossref
Günter Steiner. 2009. Rheumatoid Arthritis. Rheumatoid Arthritis 180 190 .
Nicole Fabien, Joëlle Goetz, Christelle Sordet, René-Louis Humbel & Jean Sibilia. (2008) Nouveaux autoanticorps de la polyarthrite rhumatoïde : les autoanticorps anti-peptides ou protéines citrullinées et les autres. La Presse Médicale 37:12, pages 1756-1766.
Crossref
Ulrika Böiers, Harald Lanig, Bettina Sehnert, Rikard Holmdahl & Harald Burkhardt. (2008) Collagen type II is recognized by a pathogenic antibody through germline encoded structures. European Journal of Immunology 38:10, pages 2784-2795.
Crossref
John A McGrath. (2008) Filaggrin and the great epidermal barrier grief. Australasian Journal of Dermatology 49:2, pages 67-74.
Crossref
Jonathan A. Hill, David A. Bell, William Brintnell, David Yue, Bret Wehrli, Anthony M. Jevnikar, David M. Lee, Wolfgang Hueber, William H. Robinson & Ewa Cairns. (2008) Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice. The Journal of Experimental Medicine 205:4, pages 967-979.
Crossref
Sijun Dong, Shibo Ying, Toshio Kojima, Masakazu Shiraiwa, Akira Kawada, Marie-Claire Méchin, Véronique Adoue, Stéphane Chavanas, Guy Serre, Michel Simon & Hidenari Takahara. (2008) Crucial Roles of MZF1 and Sp1 in the Transcriptional Regulation of the Peptidylarginine Deiminase Type I Gene (PADI1) in Human Keratinocytes. Journal of Investigative Dermatology 128:3, pages 549-557.
Crossref
Cyril Clavel, Leonor Nogueira, Laetitia Laurent, Cristina Iobagiu, Christian Vincent, Mireille Sebbag & Guy Serre. (2008) Induction of macrophage secretion of tumor necrosis factor α through Fcγ receptor IIa engagement by rheumatoid arthritis–specific autoantibodies to citrullinated proteins complexed with fibrinogen. Arthritis & Rheumatism 58:3, pages 678-688.
Crossref
Zoltán Szekanecz, Lilla Soós, Zoltán Szabó, Andrea Fekete, Anikó Kapitány, Anikó Végvári, Sándor Sipka, Gabriella Szücs, Sándor Szántó & Gabriella Lakos. (2007) Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis: As Good as it Gets?. Clinical Reviews in Allergy & Immunology 34:1, pages 26-31.
Crossref
Markus H. Hoffmann, Jonatan Tuncel, Karl Skriner, Makiyeh Tohidast-Akrad, Birgit Türk, Serafin Pinol-Roma, Guy Serre, Georg Schett, Josef S. Smolen, Rikard Holmdahl & Günter Steiner. (2007) The Rheumatoid Arthritis-Associated Autoantigen hnRNP-A2 (RA33) Is a Major Stimulator of Autoimmunity in Rats with Pristane-Induced Arthritis. The Journal of Immunology 179:11, pages 7568-7576.
Crossref
Céline Foulquier, Mireille Sebbag, Cyril Clavel, Sabine Chapuy-Regaud, Roula Al Badine, Marie-Claire Méchin, Christian Vincent, Rachida Nachat, Michiyuki Yamada, Hidenari Takahara, Michel Simon, Marina Guerrin & Guy Serre. (2007) Peptidyl arginine deiminase type 2 (PAD-2) and PAD-4 but not PAD-1, PAD-3, and PAD-6 are expressed in rheumatoid arthritis synovium in close association with tissue inflammation. Arthritis & Rheumatism 56:11, pages 3541-3553.
Crossref
Günter Steiner. (2007) Auto-antibodies and autoreactive T-cells in rheumatoid arthritis. Clinical Reviews in Allergy & Immunology 32:1, pages 23-35.
Crossref
Günter Steiner. (2007) Auto-antibodies and autoreactive T-cells in rheumatoid arthritis. Clinical Reviews in Allergy & Immunology 32:1.
Crossref
Kelly Tilleman, Ann Union, Tineke Cantaert, Saskia De Keyser, Annick Daniels, Dirk Elewaut, Filip De Keyser & Dieter Deforce. (2007) In pursuit of B‐cell synovial autoantigens in rheumatoid arthritis: Confirmation of citrullinated fibrinogen, detection of vimentin, and introducing carbonic anhydrase as a possible new synovial autoantigen. PROTEOMICS – Clinical Applications 1:1, pages 32-46.
Crossref
Evange Romas & Matthew T. Gillespie. (2006) Inflammation-Induced Bone Loss: Can it Be Prevented?. Rheumatic Disease Clinics of North America 32:4, pages 759-773.
Crossref
V Duplan, C Foulquier, C Clavel, R Al Badine, G Serre, A Saoudi & M Sebbag. (2006) In the rat, citrullinated autologous fibrinogen is immunogenic but the induced autoimmune response is not arthritogenic. Clinical and Experimental Immunology 145:3, pages 502-512.
Crossref
Federico Pratesi, Cristina Tommasi, Consuelo Anzilotti, Daniele Chimenti & Paola Migliorini. (2006) Deiminated Epstein-Barr virus nuclear antigen 1 is a target of anti–citrullinated protein antibodies in rheumatoid arthritis. Arthritis & Rheumatism 54:3, pages 733-741.
Crossref
Evange Romas. 2006. Osteoporosis and the Osteoporosis of Rheumatic Diseases. Osteoporosis and the Osteoporosis of Rheumatic Diseases 265 273 .
Jennifer D. Gorman. (2006) Smoking and rheumatoid arthritis: Another reason to just say no. Arthritis & Rheumatism 54:1, pages 10-13.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.