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Original

Systems biology in systemic lupus erythematosus: Integrating genes, biology and immune function

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Pages 705-709 | Published online: 07 Jul 2009

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Homaidan T. Alhomaidan, Naila Rasheed, Salem Almatrafi, Fahad H. Al-Rashdi & Zafar Rasheed. (2019) Bisphenol A modified DNA: A possible immunogenic stimulus for anti-DNA autoantibodies in systemic lupus erythematosus. Autoimmunity 52:7-8, pages 272-280.
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Nicola Cirillo. (2012) Merging experimental data and in silico analysis: a systems-level approach to autoimmune disease and cancer. Expert Review of Clinical Immunology 8:4, pages 361-372.
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Andras Perl. (2010) Pathogenic mechanisms in systemic lupus erythematosus. Autoimmunity 43:1, pages 1-6.
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Chang-Hee Suh & Hyoun-Ah Kim. (2008) Cytokines and their receptors as biomarkers of systemic lupus erythematosus. Expert Review of Molecular Diagnostics 8:2, pages 189-198.
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Jisoo Oh, Keiji Oda, Marissa Brash, W. Lawrence Beeson, Joan Sabaté, Gary E Fraser & Synnove F Knutsen. (2023) Systemic Lupus Erythematosus and the Ratio of Omega-3 to Omega-6 Fatty Acids Consumption among Women in the Adventist Health Study-2. Lupus 32:14, pages 1637-1645.
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Eugenia Enríquez-Merayo & Maria J. Cuadrado. (2023) Steroids in Lupus: Enemies or Allies. Journal of Clinical Medicine 12:11, pages 3639.
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Tao You, Xiaoyin Lin, Chunhong Zhang, Weilun Wang & Meihong Lei. (2022) Correlation between serum β2-microglobulin level and systemic lupus erythematosus disease activity: A PRISMA-compliant meta-analysis. Medicine 101:39, pages e30594.
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Vikas Kailashiya, Usha Singh & Jyotsna Kailashiya. (2022) CTLA4 gene polymorphism and its association with disease occurrence, clinical manifestations, serum markers and cytokine levels in SLE patients from North India. Indian Journal of Dermatology 67:3, pages 311.
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Deepika Lal, Monika Thakur & Chhagan Bihari. (2020) Serum Leptin Serves as an Inflammatory Activity Marker and Predicts Steroid Response in Autoimmune Hepatitis. Journal of Clinical and Experimental Hepatology 10:6, pages 574-580.
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Vikas Kailashiya, Hanjabam Barun Sharma & Jyotsna Kailashiya. (2019) Role of CTLA4 A49G polymorphism in systemic lupus erythematosus and its geographical distribution . Journal of Clinical Pathology 72:10, pages 659-662.
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Miramir Aghdashi, Simak Salami & Ahmad Nezhadisalami. (2019) Evaluation of the serum β2 Microglobulin level in patients with systemic lupus erythematosus and its correlation with disease activity. BioMedicine 9:3, pages 16.
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Saif Khan, Sajad A. Dar, Raju K. Mandal, Arshad Jawed, Mohd Wahid, Aditya K. Panda, Mohtashim Lohani, B. N. Mishra, Naseem Akhter & Shafiul Haque. (2018) Angiotensin-Converting Enzyme Gene I/D Polymorphism Is Associated With Systemic Lupus Erythematosus Susceptibility: An Updated Meta-Analysis and Trial Sequential Analysis. Frontiers in Physiology 9.
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Weiguang Luo, Bin Zhou, Qizhi Luo, Huilong Fang, Xiaoxia Zuo & Yizhou Zou. (2017) Polymorphism of keratin 1 associates with systemic lupus erythematosus and systemic sclerosis in a south Chinese population. PLOS ONE 12:10, pages e0186409.
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Elaine V. LourençoAijing LiuGiuseppe Matarese & Antonio La Cava. (2016) Leptin promotes systemic lupus erythematosus by increasing autoantibody production and inhibiting immune regulation. Proceedings of the National Academy of Sciences 113:38, pages 10637-10642.
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Gabriella Czifra, Balázs Tóth, Ildikó Kovács, Tamás Bíró, Zoltán Griger, Sándor Baráth, Tünde Tarr, Margit Zeher & Sándor Sipka. (2013) The in vitro treatment with vitamin D3 is ineffective on the expression of PKC isoenzymes, but decreases further the impaired production of IL-2 in the T lymphocytes of SLE patients. Rheumatology International 34:5, pages 717-720.
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Alexandros P. Grammatikos, Vasileios C. Kyttaris, Katalin Kis-Toth, Lisa M. Fitzgerald, Amy Devlin, Michele D. Finnell & George C. Tsokos. (2014) A T cell gene expression panel for the diagnosis and monitoring of disease activity in patients with systemic lupus erythematosus. Clinical Immunology 150:2, pages 192-200.
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M-LF Hermansen, L Hummelshøj, D Lundsgaard, L Hornum, P Keller, J Fleckner, B Fox, LK Poulsen & S Jacobsen. (2012) Increased serum β2-microglobulin is associated with clinical and immunological markers of disease activity in systemic lupus erythematosus patients. Lupus 21:10, pages 1098-1104.
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Thomas J. Covey, Janet L. Shucard, David W. Shucard, Shane Stegen & Ralph H.B. Benedict. (2012) Comparison of Neuropsychological Impairment and Vocational Outcomes in Systemic Lupus Erythematosus and Multiple Sclerosis Patients. Journal of the International Neuropsychological Society 18:03, pages 530-540.
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Joseph M. Ahearn, Chau-Ching Liu, Amy H. Kao & Susan Manzi. (2012) Biomarkers for systemic lupus erythematosus. Translational Research 159:4, pages 326-342.
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Andras Perl. (2012) Oxidative stress and endosome recycling are complementary mechanisms reorganizing the T-cell receptor signaling complex in SLE. Clinical Immunology 142:3, pages 219-222.
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Z. Griger, B. I. Tóth, S. Baráth, Á. Gyetvai, I. Kovács, T. Tarr, T. Bíró, M. Zeher & S. Sipka. (2012) Different Effects of Bortezomib on the Expressions of Various Protein Kinase C Isoenzymes in T Cells of Patients with Systemic Lupus Erythematosus and in Jurkat Cells. Scandinavian Journal of Immunology 75:2, pages 243-248.
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Erika Zilahi, Tünde Tarr, Gábor Papp, Zoltán Griger, Sándor Sipka & Margit Zeher. (2012) Increased microRNA-146a/b, TRAF6 gene and decreased IRAK1 gene expressions in the peripheral mononuclear cells of patients with Sjögren's syndrome. Immunology Letters 141:2, pages 165-168.
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Ahmad Taha Khalaf, Ji-Quan Song, Ting-Ting Gao, Xiang-Ping Yu & Tie-Chi Lei. (2011) CTLA-4 Gene Polymorphism and the Risk of Systemic Lupus Erythematosus in the Chinese Population . Journal of Biomedicine and Biotechnology 2011, pages 1-6.
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Boglarka Brugos, Emese Kiss, Csaba Dul, Wolfgang Gubisch, Gyula Szegedi, Sandor Sipka & Margit Zeher. (2010) Measurement of interleukin-1 receptor antagonist in patients with systemic lupus erythematosus could predict renal manifestation of the disease. Human Immunology 71:9, pages 874-877.
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Jufeng Zhang, Jingui Deng, Chao Zhang, Yanxin Lu, Li Liu, Qi Wu, Yong Shao, Jie Zhang, Hong Yang, Bo Yu & Jun Wan. (2010) Association of GSTT1, GSTM1 and CYP1A1 polymorphisms with susceptibility to systemic lupus erythematosus in the Chinese population. Clinica Chimica Acta 411:11-12, pages 878-881.
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Helga Kristjansdottir, Kristjan Steinsson, Iva Gunnarsson, Gerdur Gröndal, Kristjan Erlendsson & Marta E. Alarcón‐Riquelme. (2010) Lower expression levels of the programmed death 1 receptor on CD4+CD25+ T cells and correlation with the PD‐1.3A genotype in patients with systemic lupus erythematosus. Arthritis & Rheumatism 62:6, pages 1702-1711.
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Hyoun-Ah Kim, Ja-Young Jeon, Jeong-Moon Yoon & Chang-Hee Suh. (2010) Beta2-Microglobulin Can Be a Disease Activity Marker in Systemic Lupus Erythematosus. The American Journal of the Medical Sciences 339:4, pages 337-340.
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. 2010. Robbins and Cotran Pathologic Basis of Disease. Robbins and Cotran Pathologic Basis of Disease 183 257 .
Emily Walters, Virginia Rider, Nabih I. Abdou, Cindy Greenwell, Stan Svojanovsky, Peter Smith & Bruce F. Kimler. (2009) Estradiol targets T cell signaling pathways in human systemic lupus. Clinical Immunology 133:3, pages 428-436.
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Andras Perl. (2009) Emerging new pathways of pathogenesis and targets for treatment in systemic lupus erythematosus and Sjogren's syndrome. Current Opinion in Rheumatology 21:5, pages 443-447.
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Andras Perl, David R Fernandez, Tiffany Telarico, Edward Doherty, Lisa Francis & Paul E Phillips. (2009) T-cell and B-cell signaling biomarkers and treatment targets in lupus. Current Opinion in Rheumatology 21:5, pages 454-464.
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Chau-Ching Liu & Joseph M. Ahearn. (2009) The search for lupus biomarkers. Best Practice & Research Clinical Rheumatology 23:4, pages 507-523.
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Clive BowmanOlivier Delrieu. (2009) Immunogenetics of drug-induced skin blistering disorders. Part II: Synthesis. Pharmacogenomics 10:5, pages 779-816.
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Clive BowmanOlivier Delrieu. (2009) Immunogenetics of drug-induced skin blistering disorders. Part I: Perspective. Pharmacogenomics 10:4, pages 601-621.
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David R. Fernandez, Tiffany Telarico, Eduardo Bonilla, Qing Li, Sanjay Banerjee, Frank A. Middleton, Paul E. Phillips, Mary K. Crow, Stefanie Oess, Werner Muller-Esterl & Andras Perl. (2009) Activation of Mammalian Target of Rapamycin Controls the Loss of TCRζ in Lupus T Cells through HRES-1/Rab4-Regulated Lysosomal Degradation. The Journal of Immunology 182:4, pages 2063-2073.
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R. H. B. Benedict, J. L. Shucard, R. Zivadinov & D. W. Shucard. (2008) Neuropsychological Impairment in Systemic Lupus Erythematosus: A Comparison with Multiple Sclerosis. Neuropsychology Review 18:2, pages 149-166.
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Jeffrey C. Edberg, Jianming Wu, Carl D. Langefeld, Elizabeth E. Brown, Miranda C. Marion, Gerald McGwinJrJr, Michelle Petri, Rosalind Ramsey-Goldman, John D. Reveille, Summer G. Frank, Kenneth M. Kaufman, John B. Harley, Graciela S. Alarcón & Robert P. Kimberly. (2008) Genetic variation in the CRP promoter: association with systemic lupus erythematosus. Human Molecular Genetics 17:8, pages 1147-1155.
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Daniel J Wallace. (2007) Future management of systemic lupus erythematosus. Future Rheumatology 2:3, pages 229-231.
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