Advanced search
Publication Cover
Autoimmunity Volume 40, 2007 - Issue 1
Submit an article Journal homepage
113
Views
15
CrossRef citations to date
0
Altmetric
Original

Gene expression profiles reveal homeostatic dynamics during interferon-β therapy in multiple sclerosis

Viviana Annibali Department of Neurology and Center for Experimental Neurological Therapy, S. Andrea Hospital, University of Rome “La Sapienza”, Rome, Italy
,
Simone Di Giovanni Department of Neurology and Center for Experimental Neurological Therapy, S. Andrea Hospital, University of Rome “La Sapienza”, Rome, Italy
,
Stefania Cannoni Department of Neurology and Center for Experimental Neurological Therapy, S. Andrea Hospital, University of Rome “La Sapienza”, Rome, Italy
,
Elisabetta Giugni Neuroradiology, S. Andrea Hospital, University of Rome “La Sapienza”, Rome, Italy
,
Roberto Bomprezzi Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD20892, USA
,
Carlo Mattei Department of Neurology and Center for Experimental Neurological Therapy, S. Andrea Hospital, University of Rome “La Sapienza”, Rome, Italy
,
Abdel Elkahloun Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD20892, USA
,
Eliana Marina Coccia Department of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, Rome, Italy
,
Marco Alfò Department of Statistics, Probability and Applied Statistics, University of Rome “La Sapienza”, Rome, Italy
,
Francesco Orzi Department of Neurology and Center for Experimental Neurological Therapy, S. Andrea Hospital, University of Rome “La Sapienza”, Rome, Italy
,
Giovanni Ristori Department of Neurology and Center for Experimental Neurological Therapy, S. Andrea Hospital, University of Rome “La Sapienza”, Rome, Italy
&
Marco Salvetti Department of Neurology and Center for Experimental Neurological Therapy, S. Andrea Hospital, University of Rome “La Sapienza”, Rome, Italy
 show all
Pages 16-22 | Received 20 Sep 2006, Accepted 22 Nov 2006, Published online: 07 Jul 2009

Citations (15)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Rosella Mechelli, Viviana Annibali, Giovanni Ristori, Danila Vittori, Giulia Coarelli & Marco Salvetti. (2010) Multiple sclerosis etiology: beyond genes and environment. Expert Review of Clinical Immunology 6:3, pages 481-490.
Read now
P. Serrano-Fernández, S. Möller, R. Goertsches, H. Fiedler, D. Koczan, H. J. Thiesen & U. K. Zettl. (2010) Time course transcriptomics of IFNB1b drug therapy in multiple sclerosis. Autoimmunity 43:2, pages 172-178.
Read now

Articles from other publishers (13)

Silvia Romano, Michela Ferraldeschi, Francesca Bagnato, Rosella Mechelli, Emanuele Morena, Marzia Caldano, Maria Chiara Buscarinu, Arianna Fornasiero, Marco Frontoni, Viviana Nociti, Massimiliano Mirabella, Flavia Mayer, Antonio Bertolotto, Carlo Pozzilli, Nicola Vanacore, Marco Salvetti & Giovanni Ristori. (2019) Drug Holiday of Interferon Beta 1b in Multiple Sclerosis: A Pilot, Randomized, Single Blind Study of Non-inferiority. Frontiers in Neurology 10.
Crossref
Dusanka S Skundric, William W Cruikshank & Jelena Drulovic. (2015) Role of IL-16 in CD4+ T cell-mediated regulation of relapsing multiple sclerosis. Journal of Neuroinflammation 12:1.
Crossref
S. Nischwitz, H. Faber, P. G. Sämann, H. S. Domingues, G. Krishnamoorthy, M. Knop, F. Müller-Sarnowski, A. Yassouridis & F. Weber. (2014) Interferon β-1a reduces increased interleukin-16 levels in multiple sclerosis patients. Acta Neurologica Scandinavica 130:1, pages 46-52.
Crossref
Michael Hecker, Christiane Hartmann, Ole Kandulski, Brigitte Katrin Paap, Dirk Koczan, Hans-Juergen Thiesen & Uwe Klaus Zettl. (2013) Interferon-beta therapy in multiple sclerosis: the short-term and long-term effects on the patients’ individual gene expression in peripheral blood. Molecular Neurobiology 48:3, pages 737-756.
Crossref
Cornelis L Verweij. (2012) Research Highlights: Clinical relevance of the type I interferon signature in multiple sclerosis. Pharmacogenomics 13:16, pages 1883-1885.
Crossref
M Hecker, R H Goertsches, C Fatum, D Koczan, H-J Thiesen, R Guthke & U K Zettl. (2010) Network analysis of transcriptional regulation in response to intramuscular interferon-β-1a multiple sclerosis treatment. The Pharmacogenomics Journal 12:2, pages 134-146.
Crossref
Robert H Goertsches, Uwe K Zettl & Michael Hecker. (2011) Sieving treatment biomarkers from blood gene-expression profiles: a pharmacogenomic update on two types of multiple sclerosis therapy. Pharmacogenomics 12:3, pages 423-432.
Crossref
J. William Lindsey, Sandeep K. Agarwal & Filemon K. Tan. (2010) Gene Expression Changes in Multiple Sclerosis Relapse Suggest Activation of T and Non-T Cells. Molecular Medicine 17:1-2, pages 95-102.
Crossref
Kaushal S. GandhiFiona C. McKayMathew CoxCarlos RiverosNicola ArmstrongRobert N. HeardSteve VucicDavid W. WilliamsJim StankovichMatthew Brown, Patrick Danoy, Graeme J. StewartSimon Broadley, Pablo MoscatoJeannette Lechner-ScottRodney J. ScottDavid R. BoothLyn Griffiths, Mark Slee, Sharon Browning, Brian L. Browning, Trevor Kilpatrick, Justin Rubio, Victoria Perreau, Helmut Butzkeuven, Mary Tanner, Jim Wiley, Simon Foote, Jim Stankovich, Bruce Taylor, Allan Kermode, Bill Carroll & Melanie Bahlo. (2010) The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis. Human Molecular Genetics 19:11, pages 2134-2143.
Crossref
Robert H Goertsches, Michael Hecker, Dirk Koczan, Pablo Serrano-Fernandez, Steffen Moeller, Hans-Juergen Thiesen & Uwe K Zettl. (2010) Long-term genome-wide blood RNA expression profiles yield novel molecular response candidates for IFN-β-1b treatment in relapsing remitting MS. Pharmacogenomics 11:2, pages 147-161.
Crossref
Saskia VosslamberLisa GM van BaarsenCornelis L Verweij. (2009) Pharmacogenomics of IFN-β in multiple sclerosis: towards a personalized medicine approach. Pharmacogenomics 10:1, pages 97-108.
Crossref
Robert H. Goertsches, Michael Hecker & Uwe K. Zettl. (2008) Monitoring of multiple sclerosis immunotherapy. Journal of Neurology 255:S6, pages 48-57.
Crossref
Udi Rubinstein, Yifat Felder, Nana Ginzbourg, Michael Gurevich & Tamir Tuller. (2008) Editing Bayesian Networks: A New Approach for Combining Prior Knowledge and Gene Expression Measurements for Researching Diseases. Editing Bayesian Networks: A New Approach for Combining Prior Knowledge and Gene Expression Measurements for Researching Diseases.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.