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Autoimmunity Volume 40, 2007 - Issue 4
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Original

Purified apoptotic bodies stimulate plasmacytoid dendritic cells to produce IFN-alpha

BRIEF DEFINITE REPORT

P. Heyder Department of Medicine V, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany
,
I. Bekeredjian-Ding Department of Medical Microbiology and Hygiene, University of Heidelberg, Im Neuenheimer Feld 324, 69120, Heidelberg, Germany
,
M. Parcina Department of Medical Microbiology and Hygiene, University of Heidelberg, Im Neuenheimer Feld 324, 69120, Heidelberg, Germany
,
N. Blank Department of Medicine V, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany
,
A. D. Ho Department of Medicine V, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany
,
M. Herrmann Department of Internal Medicine 3, Institute of Clinical Immunology and Rheumatology, University Hospital Erlangen, 91054, Erlangen, Germany
,
Hanns-Martin Lorenz Department of Medicine V, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany
,
K. Heeg Department of Medical Microbiology and Hygiene, University of Heidelberg, Im Neuenheimer Feld 324, 69120, Heidelberg, Germany
&
M. Schiller Department of Medicine V, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany
 show all
Pages 331-332 | Published online: 07 Jul 2009

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Lotte Spel, Jaap-Jan Boelens, Stefan Nierkens & Marianne Boes. (2013) Antitumor immune responses mediated by dendritic cells: How signals derived from dying cancer cells drive antigen cross-presentation. OncoImmunology 2:11.
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Laura Andreoli, Micaela Fredi, Cecilia Nalli, Franco Franceschini, Pier Luigi Meroni & Angela Tincani. (2013) Antiphospholipid antibodies mediate autoimmunity against dying cells. Autoimmunity 46:5, pages 302-306.
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Martin Schiller, Petra Heyder, Saskia Ziegler, Anna Niessen, Laura Claßen, Anna Lauffer & Hanns-Martin Lorenz. (2013) During apoptosis HMGB1 is translocated into apoptotic cell-derived membraneous vesicles. Autoimmunity 46:5, pages 342-346.
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Isabelle Bekeredjian-Ding. (2013) B cell encounters with apoptotic cells. Autoimmunity 46:5, pages 307-311.
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Philipp Georg & Isabelle Bekeredjian-Ding. (2012) Plasmacytoid dendritic cells control B cell-derived IL-10 production. Autoimmunity 45:8, pages 579-583.
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Eva-Marie Fehr, Sonja Kierschke, Regina Max, Alexander Gerber, Hanns-Martin Lorenz & Martin Schiller. (2009) Apototic cell-derived membrane vesicles induce CD83 expression on human mdDC. Autoimmunity 42:4, pages 322-324.
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Marijo Parcina, Martin Schiller, Aline Gierschke, Klaus Heeg & Isabelle Bekeredjian-Ding. (2009) PDC expressing CD36, CD61 and IL-10 may contribute to propagation of immune tolerance. Autoimmunity 42:4, pages 353-355.
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Hanna Marie Meesmann, Marijo Parcina, Hanns-Martin Lorenz, Norbert Blank & Martin Schiller. (2009) Apo material as a trigger for inflammation in systemic lupus erythematosus. Autoimmunity 42:4, pages 251-253.
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Federico Armando, Luca Ferrari, Maria Luisa Arcari, Giacomo Azzali, Davide Dallatana, Maura Ferrari, Guerino Lombardi, Matteo Zanfabro, Rosanna Di Lecce, Paolo Lunghi, Ewan R. Cameron, Anna M. Cantoni & Attilio Corradi. (2020) Endocanalicular transendothelial crossing (ETC): A novel intravasation mode used by HEK-EBNA293-VEGF-D cells during the metastatic process in a xenograft model. PLOS ONE 15:10, pages e0239932.
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Jürgen Dieker, Jurjen Tel, Elmar Pieterse, Astrid Thielen, Nils Rother, Marinka Bakker, Jaap Fransen, Henry B. P. M. Dijkman, Jo H. Berden, Jolanda M. de Vries, Luuk B. Hilbrands & Johan van der Vlag. (2016) Circulating Apoptotic Microparticles in Systemic Lupus Erythematosus Patients Drive the Activation of Dendritic Cell Subsets and Prime Neutrophils for NETosis. Arthritis & Rheumatology 68:2, pages 462-472.
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A. Niessen, P. Heyder, S. Krienke, N. Blank, L.-O. Tykocinski, H.-M. Lorenz & M. Schiller. (2015) Apoptotic cell-derived membrane microparticles and IFN-α induce an inflammatory immune response. Journal of Cell Science.
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Georgina Galicia & Jennifer L. Gommerman. (2014) Plasmacytoid dendritic cells and autoimmune inflammation. bchm 395:3, pages 335-346.
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Stefan Landgraeber, Marcus Jäger, Joshua J. Jacobs & Nadim James Hallab. (2014) The Pathology of Orthopedic Implant Failure Is Mediated by Innate Immune System Cytokines. Mediators of Inflammation 2014, pages 1-9.
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Eva-Marie Fehr, Silvia Spoerl, Petra Heyder, Martin Herrmann, Isabelle Bekeredjian-Ding, Norbert Blank, Hanns-Martin Lorenz & Martin Schiller. (2013) Apoptotic-cell-derived membrane vesicles induce an alternative maturation of human dendritic cells which is disturbed in SLE. Journal of Autoimmunity 40, pages 86-95.
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Daniel S Smyk, Eirini I Rigopoulou, Ana Lleo, Robin D Abeles, Athanasios Mavropoulos, Charalambos Billinis, Pietro Invernizzi & Dimitrios P Bogdanos. (2011) Immunopathogenesis of primary biliary cirrhosis: an old wives' tale. Immunity & Ageing 8:1.
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Ziaur S. M. Rahman. (2011) Impaired clearance of apoptotic cells in germinal centers: implications for loss of B cell tolerance and induction of autoimmunity. Immunologic Research 51:2-3, pages 125-133.
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Luis E. Muñoz, Kirsten Lauber, Martin Schiller, Angelo A. Manfredi & Martin Herrmann. (2010) The role of defective clearance of apoptotic cells in systemic autoimmunity. Nature Reviews Rheumatology 6:5, pages 280-289.
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JĂźrgen Dieker & Sylviane Muller. (2010) Post-translational modifications, subcellular relocation and release in apoptotic microparticles: apoptosis turns nuclear proteins into autoantigens.. Folia Histochemica et Cytobiologica 47:3.
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Justin H. Fransen, Luuk B. Hilbrands, Jurjen Ruben, Monique Stoffels, Gosse J. Adema, Johan van der Vlag & Jo H. Berden. (2009) Mouse dendritic cells matured by ingestion of apoptotic blebs induce T cells to produce interleukin-17. Arthritis & Rheumatism 60:8, pages 2304-2313.
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Luis E. Muñoz, Christina Janko, Gerhard E. Grossmayer, Benjamin Frey, Reinhard E. Voll, Peter Kern, Joachim R. Kalden, Georg Schett, Rainer Fietkau, Martin Herrmann & Udo S. Gaipl. (2009) Remnants of secondarily necrotic cells fuel inflammation in systemic lupus erythematosus. Arthritis & Rheumatism 60:6, pages 1733-1742.
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Stefan Landgraeber, Sandra Jaeckel, Franz Löer, Christian Wedemeyer, Gero Hilken, Ali Canbay, Martin Totsch & Marius von Knoch. (2009) Pan-caspase inhibition suppresses polyethylene particle-induced osteolysis. Apoptosis 14:2, pages 173-181.
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Seetha U Monrad, Karl C Desch & Mariana J Kaplan. (2008) Role of dendritic cells in the pathogenesis of systemic lupus erythematosus. Future Rheumatology 3:3, pages 269-279.
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M Schiller, I Bekeredjian-Ding, P Heyder, N Blank, A D Ho & H-M Lorenz. (2007) Autoantigens are translocated into small apoptotic bodies during early stages of apoptosis. Cell Death & Differentiation 15:1, pages 183-191.
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M. Schiller, H.-M. Lorenz & N. Blank. (2007) Neue Aspekte zur Pathogenese des systemischen Lupus erythematodesNew aspects of the pathogenesis of systemic lupus erythematosus. Zeitschrift für Rheumatologie 66:6, pages 505-509.
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