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Research Article

A Th2 immune shift to heat shock protein 65 fails to arrest atherosclerosis: Proatherogenic role of Th2-deviated autoantibodies

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Pages 475-483 | Received 28 Nov 2008, Accepted 11 Mar 2009, Published online: 09 Sep 2009

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Murad Alahdal, Jing Liangliang, Lu Shiping, Xing Yun, Huashan Gao, Zhou Jialei, Waseem Hassan, Liang Jin & Cao Rongyue. (2018) New DiaP277 analogue shifts DCs to tolerogenic, and modulates NF-Kβ1 to suppress autoreactive T lymphocytes in the type 1 diabetic mice. Autoimmunity 51:5, pages 210-220.
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Lu Yong, Sun Yunxiao, Xiong Qiyan, Zhang Yu, Hou Jing, Didier JL Mekoo, Zhang Fan, Hu Xiangbing, Ma Yanjun, Liu Jingjing & Li Taiming. (2010) Immunization with P277 induces vascular leak syndrome in C57BL/6 mice via endothelial damage. Autoimmunity 43:8, pages 654-663.
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Articles from other publishers (10)

Axel P. Villani, Ana B. Pavel, Jianni Wu, Marie Fernandes, Catherine Maari, Etienne Saint‐Cyr Proulx, Carolyn Jack, Jacob Glickman, Seulah Choi, Helen He, Benjamin Ungar, Yeriel Estrada, Naoya Kameyama, Ning Zhang, Juana Gonzales, Jean‐Claude Tardif, James G. Krueger, Robert Bissonnette & Emma Guttman‐Yassky. (2021) Vascular inflammation in moderate‐to‐severe atopic dermatitis is associated with enhanced Th2 response. Allergy 76:10, pages 3107-3121.
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Constanze Kuehn, Miyuki Tauchi, Roman Furtmair, Katharina Urschel, Dorette Raaz‐Schrauder, Anna‐Lena Neumann, Stefan J. Frohberger, Achim Hoerauf, Susanne Regus, Werner Lang, Tolga Atilla Sagban, Florian Matthias Stumpfe, Stephan Achenbach, Marc P. Hübner & Barbara Dietel. (2019) Filarial extract of Litomosoides sigmodontis induces a type 2 immune response and attenuates plaque development in hyperlipidemic ApoE‐knockout mice . The FASEB Journal 33:5, pages 6497-6513.
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Tomasz J. GuzikDominik S. SkibaRhian M. TouyzDavid G. Harrison. (2017) The role of infiltrating immune cells in dysfunctional adipose tissue. Cardiovascular Research 113:9, pages 1009-1023.
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Lili Shen, Shiping Lu, Dongcheng Huang, Guoliang Li, Kunfeng Liu, Rongyue Cao, Li Zong, Liang Jin & Jie Wu. (2017) A rationally designed peptide IA-2-P2 against type 1 diabetes in streptozotocin-induced diabetic mice. Diabetes and Vascular Disease Research 14:3, pages 184-190.
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A. Safa, H.R. Rashidinejad, M. Khalili, S. Dabiri, M. Nemati, M.M. Mohammadi & A. Jafarzadeh. (2016) Higher circulating levels of chemokines CXCL10, CCL20 and CCL22 in patients with ischemic heart disease. Cytokine 83, pages 147-157.
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Qiyan Xiong, Jiao Feng, Yu Zhang, Yunxiao Sun, Yong Lu, Taiming Li, Xiaohong Zhang, Rongyue Cao, Liang Jin & Jie Wu. (2016) Promotion of atherosclerosis in high cholesterol diet-fed rabbits by immunization with the P277 peptide. Immunology Letters 170, pages 80-87.
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Yanjun Ma, Jingjing Liu, Jing Hou, Yuankai Dong, Yong Lu, Liang Jin, Rongyue Cao, Taiming Li & Jie Wu. (2014) Oral Administration of Recombinant Lactococcus lactis Expressing HSP65 and Tandemly Repeated P277 Reduces the Incidence of Type I Diabetes in Non-Obese Diabetic Mice. PLoS ONE 9:8, pages e105701.
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JIE YANG, YANFEI XIE, HUAQIAN WANG, YI YAO, JING HOU, YANJUN MA, QING ZHANG, YUN XING, JIE WU, TAIMING LI, JUNNIAN ZHENG, JINGJING LIU & RONGYUE CAO. (2013) Administration of heat shock protein 65 inhibits murine melanoma growth in vivo. Molecular Medicine Reports 7:1, pages 171-176.
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Qingbo XuBernhard MetzlerMarjan Jahangiri & Kaushik Mandal. (2012) Molecular chaperones and heat shock proteins in atherosclerosis. American Journal of Physiology-Heart and Circulatory Physiology 302:3, pages H506-H514.
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Yan-Jun Ma, Yong Lu, Jing Hou, Yuan-Kai Dong, Ming-Zhu Du, Yun Xing, Chi-Yu Ge, Mao-Lei Xu, Liang Jin, Rong-Yue Cao, Tai-Ming Li, Jie Wu & Jing-Jing Liu. (2011) Vaccination of non-obese diabetic mice with a fragment of peptide P277 attenuates insulin-dependent diabetes mellitus. International Immunopharmacology 11:9, pages 1298-1302.
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