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Original Article

Baseline adiponectin and leptin levels in predicting an increased risk of disease activity in rheumatoid arthritis: A meta-analysis and systematic review

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Pages 547-553 | Received 09 Mar 2016, Accepted 30 Jul 2016, Published online: 30 Sep 2016

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Haruka Tsuchiya & Keishi Fujio. (2022) Emerging role of leptin in joint inflammation and destruction. Immunological Medicine 45:1, pages 27-34.
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Bożena Targońska-Stępniak & Krzysztof Grzechnik. (2022) Adiponectin and Leptin as Biomarkers of Disease Activity and Metabolic Disorders in Rheumatoid Arthritis Patients. Journal of Inflammation Research Volume 15, pages 5845-5855.
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Mrinalini Dey, Sizheng S Zhao, Robert J Moots, Sytske Anne Bergstra, Robert B Landewe & Nicola J Goodson. (2022) The association between increased body mass index and response to conventional synthetic disease-modifying anti-rheumatic drug treatment in rheumatoid arthritis: results from the METEOR database. Rheumatology 61:2, pages 713-722.
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Ali Taylan, Baris Akinci, Burak Toprak, Merih Birlik, Fatma Demet Arslan, Hasan Ekerbicer, Baris Gundogdu, Ayfer Colak & Bahar Engin. (2021) Association of Leptin Levels and Disease Activity in Patients with Early Rheumatoid Arthritis. Archives of Medical Research 52:5, pages 544-553.
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Ju-Ryoung Kim & Hyun Ah Kim. (2020) Molecular Mechanisms of Sex-Related Differences in Arthritis and Associated Pain. International Journal of Molecular Sciences 21:21, pages 7938.
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Milton Packer, Carolyn S.P. Lam, Lars H. Lund, Mathew S. Maurer & Barry A. Borlaug. (2020) Characterization of the inflammatory‐metabolic phenotype of heart failure with a preserved ejection fraction: a hypothesis to explain influence of sex on the evolution and potential treatment of the disease . European Journal of Heart Failure 22:9, pages 1551-1567.
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George E. Fragoulis, Ismini Panayotidis & Elena Nikiphorou. (2020) Cardiovascular Risk in Rheumatoid Arthritis and Mechanistic Links: From Pathophysiology to Treatment. Current Vascular Pharmacology 18:5, pages 431-446.
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Milton Packer. (2020) Link Between Synovial and Myocardial Inflammation: Conceptual Framework to Explain the Pathogenesis of Heart Failure with Preserved Ejection Fraction in Patients with Systemic Rheumatic Diseases. Cardiac Failure Review 6.
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Yu-Lan Zhao, Tian-Ping Zhang, Jun Wu, Bao-Zhu Li, Xiao-Mei Li, Hai-Feng Pan & Dong-Qing Ye. (2020) Association of adiponectin and adiponectin receptor gene polymorphisms with rheumatoid arthritis in a Chinese population. Postgraduate Medical Journal 96:1133, pages 149-155.
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I. V. Chadaeva, D. A. Rasskazov, E. B. Sharypova, I. A. Drachkova, E. A. Oshchepkova, L. K. Savinkova, P. M. Ponomarenko, M. P. Ponomarenko, N. A. Kolchanov & V. A. Kozlov. (2020) Сandidate SNP-markers of rheumatoid arthritis that can significantly alter the affinity of the TATA-binding protein for human gene promoters. Vavilov Journal of Genetics and Breeding 23:8, pages 1047-1058.
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In Ah Choi, Akira Sagawa, Eun Young Lee, Eun Bong Lee & Yeong Wook Song. (2020) Tocilizumab Increases Body Weight and Serum Adipokine Levels in Patients with Rheumatoid Arthritis Independently of their Treatment Response: a Retrospective Cohort Study. Journal of Korean Medical Science 35:22.
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Mar Carrión, Klaus W. Frommer, Selene Pérez-García, Ulf Müller-Ladner, Rosa P. Gomariz & Elena Neumann. (2019) The Adipokine Network in Rheumatic Joint Diseases. International Journal of Molecular Sciences 20:17, pages 4091.
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Iona MᵃᶜDonald, Shan-Chi Liu, Chien-Chung Huang, Shu-Jui Kuo, Chun-Hao Tsai & Chih-Hsin Tang. (2019) Associations between Adipokines in Arthritic Disease and Implications for Obesity. International Journal of Molecular Sciences 20:6, pages 1505.
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Milton Packer. (2018) The conundrum of patients with obesity, exercise intolerance, elevated ventricular filling pressures and a measured ejection fraction in the normal range. European Journal of Heart Failure 21:2, pages 156-162.
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Beuy Joob & Viroj Wiwanitkit. (2019) Adiponectin and rheumatoid arthritis. Indian Journal of Rheumatology 14:4, pages 330.
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Silje Stokke Kvistad, Kjell-Morten Myhr, Trygve Holmøy, Jūratė Šaltytė Benth, Stig Wergeland, Antonie G. Beiske, Kristian S. Bjerve, Harald Hovdal, Rune Midgard, Jørn V. Sagen & Øivind Torkildsen. (2018) Serum levels of leptin and adiponectin are not associated with disease activity or treatment response in multiple sclerosis. Journal of Neuroimmunology 323, pages 73-77.
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Elena Nikiphorou & George E. Fragoulis. (2018) Inflammation, obesity and rheumatic disease: common mechanistic links. A narrative review. Therapeutic Advances in Musculoskeletal Disease 10:8, pages 157-167.
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Vera Francisco, Jesús Pino, Victor Campos-Cabaleiro, Clara Ruiz-Fernández, Antonio Mera, Miguel A. Gonzalez-Gay, Rodolfo Gómez & Oreste Gualillo. (2018) Obesity, Fat Mass and Immune System: Role for Leptin. Frontiers in Physiology 9.
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Luca Navarini, Domenico Paolo Emanuele Margiotta, Marta Vadacca & Antonella Afeltra. (2018) Leptin in autoimmune mechanisms of systemic rheumatic diseases. Cancer Letters 423, pages 139-146.
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José Antonio de Jesús Batún-Garrido, Marisol Salas-Magaña, Isela Esther Juárez-Rojop, Eúfrates Hernández-Núñez & Francisco Olán. (2018) Relación entre las concentraciones de la leptina y la actividad de la enfermedad en pacientes con artritis reumatoide. Medicina Clínica 150:9, pages 341-344.
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José Antonio de Jesús Batún-Garrido, Marisol Salas-Magaña, Isela Esther Juárez-Rojop, Eúfrates Hernández-Núñez & Francisco Olán. (2018) Relationship between leptin concentrations and disease activity in patients with rheumatoid arthritis. Medicina Clínica (English Edition) 150:9, pages 341-344.
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José Antonio De Jesús Batún-Garrido, Marisol Salas-Magaña & Isela Esther Juárez-Rojop. (2017) Association between leptin and IL-6 concentrations with cardiovascular risk in patients with rheumatoid arthritis. Clinical Rheumatology 37:3, pages 631-637.
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Miaomiao WangJing WeiHan LiXunli OuyangXiaotong SunYawei TangHaifeng ChenBing WangXia Li. (2018) Leptin Upregulates Peripheral CD4 + CXCR5 + ICOS + T Cells via Increased IL-6 in Rheumatoid Arthritis Patients . Journal of Interferon & Cytokine Research 38:2, pages 86-92.
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Carlo Selmi. (2017) Autoimmunity in 2016. Clinical Reviews in Allergy & Immunology 53:1, pages 126-139.
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Vanessa DeClercq, Yunsong Cui, Cynthia Forbes, Scott A. Grandy, Melanie Keats, Louise Parker, Ellen Sweeney, Zhijie Michael Yu & Trevor J. B. Dummer. (2017) Adiposity Measures and Plasma Adipokines in Females with Rheumatoid and Osteoarthritis. Mediators of Inflammation 2017, pages 1-9.
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