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Original Articles

Icariin alleviates rheumatoid arthritis via regulating miR-223-3p/NLRP3 signalling axis

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Pages 450-458 | Received 12 Jun 2020, Accepted 10 Oct 2020, Published online: 21 Oct 2020

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Read on this site (7)

Lingyun Zhao, Qingze Wu, Yiying Long, Qirui Qu, Fang Qi, Li Liu, Liang Zhang & Kun Ai. (2023) microRNAs: critical targets for treating rheumatoid arthritis angiogenesis. Journal of Drug Targeting 0:0, pages 1-20.
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Yuwei Peng, Meng Zhang & Jiangkang Hu. (2024) Non-coding RNAs involved in fibroblast-like synoviocyte functioning in arthritis rheumatoid: From pathogenesis to therapy. Cytokine 173, pages 156418.
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Xuan Qi, Ronghua Wang, Lu Jin, Yu Tian, Hongtao Jin, Yuxiang Han, Chao Sun, Meng Ding & Huifang Guo. (2023) MiR-223-3p Aggravates Ocular Inflammation in Sjögren’s Syndrome. Endocrine, Metabolic & Immune Disorders - Drug Targets 23:8, pages 1087-1095.
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Yiping Zhang, Meiwen Yang, Hongyan Xie, Fenfang Hong & Shulong Yang. (2023) Role of miRNAs in Rheumatoid Arthritis Therapy. Cells 12:13, pages 1749.
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Jiujie Yang, Zhi Li, Linna Wang, Xiaoyun Yun, Yaling Zeng, Jerome P.L. Ng, Hanghong Lo, Yan Wang, Kaixi Zhang, Betty Yuen Kwan Law & Vincent Kam Wai Wong. (2022) The role of non-coding RNAs (miRNA and lncRNA) in the clinical management of rheumatoid arthritis. Pharmacological Research 186, pages 106549.
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Eduardo Delabio Auer, Denisson de Carvalho Santos, Ismael Júnior Valério de Lima & Angelica Beate Winter Boldt. (2022) Non-coding RNA network associated with obesity and rheumatoid arthritis. Immunobiology 227:6, pages 152281.
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Gabsik Yang, Han Chang Kang, Yong-Yeon Cho, Hye Suk Lee & Joo Young Lee. (2022) Inflammasomes and their roles in arthritic disease pathogenesis. Frontiers in Molecular Biosciences 9.
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Ye Tian, Gang Xu, Hong Gao, Hong-Yan Xie, Yu-Lin Leng, Xiao-Xu Fu & Chun-Guang Xie. (2022) The Mitigatory Effect of Shen-Qi Compound on the Diabetic Thoracic Aortic Complications through Inhibiting the Inflammatory Microenvironment by miR-223-3p/RBP-J/IRF8 Axis. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-15.
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Zhi-Ming Wu, Yan-Ru Xiang, Xiao-Bo Zhu, Xiao-Dong Shi, Sha Chen, Xin Wan & Jian Guo. (2022) Icariin represses the inflammatory responses and survival of rheumatoid arthritis fibroblast-like synoviocytes by regulating the TRIB1/TLR2/NF-kB pathway. International Immunopharmacology 110, pages 108991.
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Xiaoya Cui, Jian Liu, Lili Zhang, Xiaoli Wang, Xiaochuang Liu & Hui Jiang. (2022) Network pharmacology approach and molecular docking to explore the potential mechanism of Wu-Wei-Wen-Tong Chubi capsules in rheumatoid arthritis. Naunyn-Schmiedeberg's Archives of Pharmacology 395:9, pages 1061-1073.
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Yu Jia, Dongze Li, Jing Yu, Wenli Jiang, Xiaoyang Liao & Qian Zhao. (2022) Potential diabetic cardiomyopathy therapies targeting pyroptosis: A mini review. Frontiers in Cardiovascular Medicine 9.
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Xueling Liu, Zhiguo Wang, Hua Qian, Wenhua Tao, Ying Zhang, Chunyan Hu, Weiwei Mao & Qi Guo. (2022) Natural medicines of targeted rheumatoid arthritis and its action mechanism. Frontiers in Immunology 13.
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Congke Zhao, Liqing Hu, Xiangrong He, Lijun Li, Minghui Yin, Abraham Terkpertey Tettey, Yu Wang, Jingshan Shen, Siyuan Tang, Chunhui Wu, Qianbin Li, Zhen Wang & Xiaohui Li. (2022) TPN171H alleviates pulmonary hypertension via inhibiting inflammation in hypoxia and monocrotaline-induced rats. Vascular Pharmacology 145, pages 107017.
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Hui Yin, Na Liu, Keshav Raj Sigdel & Lihua Duan. (2022) Role of NLRP3 Inflammasome in Rheumatoid Arthritis. Frontiers in Immunology 13.
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Yunteng Xu, Hui Yan, Xin Zhang, Junkuan Zhuo, Yidan Han, Haifeng Zhang, Dingbang Xie, Xin Lan, Wanping Cai, Xiaoning Wang, Shanshan Wang & Xihai Li. (2022) Roles of Altered Macrophages and Cytokines: Implications for Pathological Mechanisms of Postmenopausal Osteoporosis, Rheumatoid Arthritis, and Alzheimer’s Disease. Frontiers in Endocrinology 13.
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Yufei Zeng, Yilin Xiong, Tao Yang, Yan Wang, Jing Zeng, Shaoyu Zhou, Yunmei Luo & Lisheng Li. (2022) Icariin and its metabolites as potential protective phytochemicals against cardiovascular disease: From effects to molecular mechanisms. Biomedicine & Pharmacotherapy 147, pages 112642.
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Li Zang, Fang Gao, Aijing Huang, Yalan Zhang, Yangyan Luo, Lijia Chen & Nan Mao. (2022) Icariin inhibits epithelial mesenchymal transition of renal tubular epithelial cells via regulating the miR-122-5p/FOXP2 axis in diabetic nephropathy rats. Journal of Pharmacological Sciences 148:2, pages 204-213.
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Lin Hu, Ziyuan Wang, Huan Li, Jiarui Wei, Fengyue Tang, Qing Wang, Jing Wang, Xiaoqiao Zhang & Qiufang Zhang. (2022) Icariin inhibits isoproterenol-induced cardiomyocyte hypertropic injury through activating autophagy via the AMPK/mTOR signaling pathway. Biochemical and Biophysical Research Communications 593, pages 65-72.
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Fengli Zhang, Yanfen Yin, Wenwen Xu, Yanan Song, Zhou Zhou, Xin Sun & Ping Li. (2022) Icariin inhibits gastric cancer cell growth by regulating the hsa_circ_0003159/miR-223-3p/NLRP3 signaling axis. Human & Experimental Toxicology 41, pages 096032712210973.
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Milad Ashrafizadeh, Ali Zarrabi, Ebrahim Mostafavi, Amir Reza Aref, Gautam Sethi, Lingzhi Wang & Vinay Tergaonkar. (2022) Non-coding RNA-based regulation of inflammation. Seminars in Immunology 59, pages 101606.
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Qiudong Yang, Wenhua Zhao, Yuyi Chen, Yue Chen, Jiali Shi, Ran Qin, Hua Wang, Ruixia Wang, Hua Yuan & Wen Sun. (2021) RelA/MicroRNA-30a/NLRP3 signal axis is involved in rheumatoid arthritis via regulating NLRP3 inflammasome in macrophages. Cell Death & Disease 12:11.
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Yuan Wang, Shujing Chen, Kunze Du, Chunxiao Liang, Shuangqi Wang, Evans Owusu Boadi, Jin Li, Xiaoli Pang, Jun He & Yan-xu Chang. (2021) Traditional herbal medicine: Therapeutic potential in rheumatoid arthritis. Journal of Ethnopharmacology 279, pages 114368.
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Hong-Xia Yan, Chun-Fang Xu, Hong Yang, Xiao-Ya Wen, Zhi-Peng Wang, Yan-Hong Chen, Jing-Xue Liu, Wan-Sheng Chen, Shou-Hong Gao & Xia Tao. (2021) Network Pharmacology-Based Analysis on the Curative Effect of Kunxian Capsules against Rheumatoid Arthritis. Evidence-Based Complementary and Alternative Medicine 2021, pages 1-11.
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