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Research Article

Biological Role of the N-Formyl Peptide Receptors

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Pages 103-127 | Published online: 08 Oct 2008

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Antonia Cianciulli, Angela Acquafredda, Pasqua Cavallo, Concetta Saponaro, Rosa Calvello, Vincenzo Mitolo & Maria Antonietta Panaro. (2009) f-Met-Leu-Phe stimulates nitric oxide production in chick embryo neurons: the role of NF-kB. Immunopharmacology and Immunotoxicology 31:1, pages 51-63.
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M.A. Panaro, C.I. Mitolo, A. Acquafredda, A. Cianciulli, C. Porro & V. Mitolo. (2008) Mutation, Selection, and Functional Repair in Formyl Peptide Receptor Genes: A View on the Selection Processes Occurring in This Gene Subfamily. Immunopharmacology and Immunotoxicology 30:2, pages 383-397.
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M.A. Panaro, M. Saccia, A. Acquafredda, A. Cianciulli, C.I. Mitolo, N. Gagliardi & V. Mitolo. (2008) Structural Relatedness Between the 18S rRNA Genes and the Formyl Peptide Receptor Genes: New Insights into the Phylogenesis of Immune Receptors. Immunopharmacology and Immunotoxicology 30:2, pages 291-305.
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M.A. Panaro, A. Acquafredda, M. Sisto, S. Lisi, R. Calvello, C.I. Mitolo, A. Cianciulli & V. Mitolo. (2007) Formyl Peptide Receptors on Immune and Nonimmune Cells: Analysis of Sequence Conservation in FPR Genes. Immunopharmacology and Immunotoxicology 29:2, pages 243-269.
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M.A. Panaro, A. Cianciulli, A. Acquafredda, S. Lisi, C.I. Mitolo, M. Sisto, P. Cavallo & V. Mitolo. (2007) Modeling of Granulocyte Cytoskeletal Responses Following fMLP Challenging. Immunopharmacology and Immunotoxicology 29:2, pages 201-224.
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M. Sisto, M.A. Panaro, A. Acquafredda, S. Lisi, A.B. Maffione & V. Mitolo. (2006) Chemokine CXC Receptor 4: An Evolutionary Approach. Immunopharmacology and Immunotoxicology 28:4, pages 715-738.
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S. Lisi, R. Calvello, M.A. Panaro, A.B. Maffione, M. Sisto & V. Mitolo. (2006) The 18S rRNA is Basically Composed of Two Tandem Quasirepeats. Insights into the Evolution of Some Innate Immunity Receptors. Immunopharmacology and Immunotoxicology 28:4, pages 651-663.
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D. D. Zhernossekov, Y. M. Roka-Moiia & T. V. Grinenko. (2016) Extracellular annexins in hemostasis system. Biopolymers and Cell 32:2, pages 98-104.
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C. Watters, D. Fleming, D. Bishop & K.P. Rumbaugh. 2016. Host-Microbe Interactions. Host-Microbe Interactions 193 239 .
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Crossref
Xiaoqiang Wang & Shuguang Zhang. (2011) Production of a Bioengineered G-Protein Coupled Receptor of Human Formyl Peptide Receptor 3. PLoS ONE 6:8, pages e23076.
Crossref
Rosa Calvello, Vincenzo Mitolo, Angela Acquafredda, Antonia Cianciulli & Maria Antonietta Panaro. (2011) Plasma membrane damage sensing and repairing. Role of heterotrimeric G-proteins and the cytoskeleton. Toxicology in Vitro 25:5, pages 1067-1074.
Crossref
Rudolf Lampé, Sándor Szűcs, Róza Ádány & Robert Póka. (2011) Granulocyte superoxide anion production and regulation by plasma factors in normal and preeclamptic pregnancy. Journal of Reproductive Immunology 89:2, pages 199-206.
Crossref
Rinshi S. Kasai, Kenichi G. N. Suzuki, Eric R. Prossnitz, Ikuko Koyama-Honda, Chieko Nakada, Takahiro K. Fujiwara & Akihiro Kusumi. (2011) Full characterization of GPCR monomer–dimer dynamic equilibrium by single molecule imaging. Journal of Cell Biology 192:3, pages 463-480.
Crossref
Mariantonella Colucci, Marica Mastriota, Francesco Maione, Amalia Di Giannuario, Nicola Mascolo, Maura Palmery, Cinzia Severini, Mauro Perretti & Stefano Pieretti. (2011) Guinea pig ileum motility stimulation elicited by N-formyl-Met-Leu-Phe (fMLF) involves neurotransmitters and prostanoids. Peptides 32:2, pages 266-271.
Crossref
Lydia Spurr, Suchita Nadkarni, Magali Pederzoli-Ribeil, Nicolas J. Goulding, Mauro Perretti & Fulvio D'Acquisto. (2011) Comparative analysis of Annexin A1-formyl peptide receptor 2/ALX expression in human leukocyte subsets. International Immunopharmacology 11:1, pages 55-66.
Crossref
Tiffany Tran, Pedro Paz, Sharlene Velichko, Jill Cifrese, Praveen Belur, Ken D. Yamaguchi, Karin Ku, Parham Mirshahpanah, Anthony T. Reder & Ed Croze. (2010) Interferonβ-1b Induces the Expression of RGS1 a Negative Regulator of G-Protein Signaling. International Journal of Cell Biology 2010, pages 1-12.
Crossref
F Kalinec, P Webster, A Maricle, D Guerrero, DN Chakravarti, B Chakravarti, R Gellibolian & G Kalinec. (2009) Glucocorticoid-stimulated, transcription-independent release of annexin A1 by cochlear Hensen cells. British Journal of Pharmacology 158:7, pages 1820-1834.
Crossref
E. Schepers, G. Glorieux, A. Dhondt, L. Leybaert & R. Vanholder. (2008) Role of symmetric dimethylarginine in vascular damage by increasing ROS via store-operated calcium influx in monocytes. Nephrology Dialysis Transplantation 24:5, pages 1429-1435.
Crossref
Ling-Yu Chen, Warren W. Pan, Miao Chen, Jain-Dong Li, Wei Liu, Guoqiang Chen, Shuang Huang, Thomas J. Papadimos & Zhixing K. Pan. (2009) Synergistic Induction of Inflammation by Bacterial Products Lipopolysaccharide and fMLP: An Important Microbial Pathogenic Mechanism. The Journal of Immunology 182:4, pages 2518-2524.
Crossref
F D'Acquisto, M Perretti & R J Flower. (2008) Annexin-A1: a pivotal regulator of the innate and adaptive immune systems. British Journal of Pharmacology 155:2, pages 152-169.
Crossref
José Luis Rodríguez‐Fernández & Lorena Riol‐Blanco. 2005. Encyclopedia of Life Sciences. Encyclopedia of Life Sciences.
Jane Lattin, David A Zidar, Kate Schroder, Stuart Kellie, David A Hume & Matthew J Sweet. (2007) G-protein-coupled receptor expression, function, and signaling in macrophages. Journal of Leukocyte Biology 82:1, pages 16-32.
Crossref

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