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Immunopharmacology and Immunotoxicology Volume 28, 2006 - Issue 2
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Research Article

Intracellular Th1/Th2 Balance of Pulmonary CD4+ T Cells in Patients with Active Interstitial Pneumonia Evaluated by Serum KL-6

Yasuo Shimizu Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Gunma, Japan; Numata National Hospital, Numata City, Gunma, Japan
,
Hidemasa Kuwabara Numata National Hospital, Numata City, Gunma, Japan
,
Akihiro Ono Numata National Hospital, Numata City, Gunma, Japan
,
Seiichi Higuchi Numata National Hospital, Numata City, Gunma, Japan
,
Takeshi Hisada Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Gunma, Japan; Numata National Hospital, Numata City, Gunma, Japan
,
Kunio Dobashi Gunma University School of Health Sciences, Gunma, Japan
,
Mitsuyoshi Utsugi Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Gunma, Japan
,
Yoshinori Mita Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Gunma, Japan
&
Masatomo Mori Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Gunma, Japan
 show all
Pages 295-304 | Published online: 08 Oct 2008

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Paolo Spagnolo, Roberto Tonelli, Anna Valeria Samarelli, Gioele Castelli, Elisabetta Cocconcelli, Simone Petrarulo, Stefania Cerri, Nicol Bernardinello, Enrico Clini, Marina Saetta & Elisabetta Balestro. (2022) The role of immune response in the pathogenesis of idiopathic pulmonary fibrosis: far beyond the Th1/Th2 imbalance. Expert Opinion on Therapeutic Targets 26:7, pages 617-631.
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Yasuo Morimoto, Akira Ogami, Motoi Todoroki, Makoto Yamamoto, Masahiro Murakami, Masami Hirohashi, Takako Oyabu, Toshihiko Myojo, Ken-Ichiro Nishi, Chikara Kadoya, Sayumi Yamasaki, Hiroko Nagatomo, Katsuhide Fujita, Shigehisa Endoh, Kunio Uchida, Kazuhiro Yamamoto, Norihiro Kobayashi, Junko Nakanishi & Isamu Tanaka. (2010) Expression of inflammation-related cytokines following intratracheal instillation of nickel oxide nanoparticles. Nanotoxicology 4:2, pages 161-176.
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Sho Sendo, Jun Saegusa, Hirotaka Yamada, Keisuke Nishimura & Akio Morinobu. (2019) Tofacitinib facilitates the expansion of myeloid-derived suppressor cells and ameliorates interstitial lung disease in SKG mice. Arthritis Research & Therapy 21:1.
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Sho Sendo, Jun Saegusa, Takaichi Okano, Soshi Takahashi, Kengo Akashi & Akio Morinobu. (2017) CD11b+Gr-1 dim Tolerogenic Dendritic Cell-Like Cells Are Expanded in Interstitial Lung Disease in SKG Mice . Arthritis & Rheumatology 69:12, pages 2314-2327.
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Avner Friedman & Wenrui Hao. (2017) Mathematical modeling of liver fibrosis. Mathematical Biosciences and Engineering 14:1, pages 143-164.
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Shi Li, Xiaofei Hu, Zheng Wang, Meng Wu & Jinnong Zhang. (2015) Different profiles of notch signaling in cigarette smoke-induced pulmonary emphysema and bleomycin-induced pulmonary fibrosis. Inflammation Research 64:5, pages 363-371.
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Aoi Shiomi & Takashi Usui. (2015) Pivotal Roles of GM-CSF in Autoimmunity and Inflammation. Mediators of Inflammation 2015, pages 1-13.
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Aoi Shiomi, Takashi Usui, Yuki Ishikawa, Masakazu Shimizu, Kosaku Murakami & Tsuneyo Mimori. (2014) GM-CSF but Not IL-17 Is Critical for the Development of Severe Interstitial Lung Disease in SKG Mice. The Journal of Immunology 193:2, pages 849-859.
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Dianne M. Walters, Kevin M. White, Ushma Patel, Martin J. Davis, Roberta M. Veluci‐Marlow, Solomon Raju Bhupanapadu Sunkesula, James C. Bonner, Jessica R. Martin, Wes Gladwell & Steven R. Kleeberger. (2013) Genetic susceptibility to interstitial pulmonary fibrosis in mice induced by vanadium pentoxide (V 2 O 5 ) . The FASEB Journal 28:3, pages 1098-1112.
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Nevins W Todd, Irina G Luzina & Sergei P Atamas. (2012) Molecular and cellular mechanisms of pulmonary fibrosis. Fibrogenesis & Tissue Repair 5:1.
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Samuel L. Collins, Yee Chan-Li, Robert W. Hallowell, Jonathan D. Powell & Maureen R. Horton. (2012) Pulmonary Vaccination as a Novel Treatment for Lung Fibrosis. PLoS ONE 7:2, pages e31299.
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Yasuhiro ShimojimaWataru IshiiMasayuki MatsudaShu-ichi Ikeda. (2012) Phenotypes of Peripheral Blood Lymphocytes and Cytokine Expression in Polymyositis and Dermatomyositis before Treatment and after Clinical Remission. Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders 5, pages CMAMD.S10272.
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Anagha A. Divekar, Dinesh Khanna, Fereidoun Abtin, Paul Maranian, Rajeev Saggar, Rajan Saggar, Daniel E. Furst & Ram Raj Singh. (2011) Treatment with imatinib results in reduced IL-4-producing T cells, but increased CD4+ T cells in the broncho-alveolar lavage of patients with systemic sclerosis. Clinical Immunology 141:3, pages 293-303.
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Yasuo Shimizu, Shinichi Matsuzaki, Takahiro Satoh, Masashi Koka, Akihito Yokoyama, Takeru Ohkubo, Yasuyuki Ishii, Tomihiro Kamiya, Makoto Fueki, Masatomo Mori & Kunio Dobashi. (2011) In-air microparticle induced X-ray emission analysis of particles in interstitial pneumonia lung tissue obtained by transbronchial biopsy. Journal of Clinical Biochemistry and Nutrition 49:2, pages 125-130.
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Gianfranco Ferraccioli, Maria De Santis, Giusy Peluso, Rosanna Inzitari, Chiara Fanali, Silvia Laura Bosello, Federica Iavarone & Massimo Castagnola. (2010) Proteomic approaches to Sjögren's syndrome: A clue to interpret the pathophysiology and organ involvement of the disease. Autoimmunity Reviews 9:9, pages 622-626.
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Y. Shimizu, K. Dobashi, K. Endou, A. Ono, N. Yanagitani, M. Utsugi, T. Sano, T. Ishizuka, K. Shimizu, S. Tanaka & M. Mori. (2010) Decreased Interstitial FOXP3 + Lymphocytes in Usual Interstitial Pneumonia with Discrepancy of CXCL12/CXCR4 Axis . International Journal of Immunopathology and Pharmacology 23:2, pages 449-461.
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Yasuo Shimizu, Noriaki Sunaga, Kunio Dobashi, Makoto Fueki, Naoto Fueki, Sohei Makino & Masatomo Mori. (2009) Serum markers in interstitial pneumonia with and without Pneumocystis jiroveciicolonization: a prospective study. BMC Infectious Diseases 9:1.
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Ann L. Parke. (2008) Pulmonary Manifestations of Primary Sjögren's Syndrome. Rheumatic Disease Clinics of North America 34:4, pages 907-920.
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Bernard Vandooren, Tineke Cantaert, Mariëtte Ter Borg, Troy Noordenbos, Rodger Kuhlman, Daniëlle Gerlag, Tim Bongartz, Kris Reedquist, Paul P. Tak & Dominique Baeten. (2008) Tumor necrosis factor α drives cadherin 11 expression in rheumatoid inflammation. Arthritis & Rheumatism 58:10, pages 3051-3062.
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Irina G Luzina, Nevins W Todd, Aldo T Iacono & Sergei P Atamas. (2008) Roles of T lymphocytes in pulmonary fibrosis. Journal of Leukocyte Biology 83:2, pages 237-244.
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