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Research Article

Aqueous Extract of Rhodiola imbricata Rhizome Stimulates Proinflammatory Mediators via Phosphorylated IκB and Transcription Factor Nuclear Factor-κB

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Pages 201-212 | Published online: 08 Oct 2008

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Monika Jamioł, Jacek Wawrzykowski, Marta Dec, Agata Wilk & Michał Czelej. (2023) Comparison of Various Techniques for the Extraction, Analysis of Compounds and Determination of Antioxidant Activities of Rhodiola Spp. - A Review. Food Reviews International 39:1, pages 467-487.
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K. P. Mishra, Lilly Ganju & S. B. Singh. (2012) Anti-cellular and immunomodulatory potential of aqueous extract of Rhodiola imbricata rhizome. Immunopharmacology and Immunotoxicology 34:3, pages 513-518.
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K.P. Mishra, Sudipta Chanda, Kirti Shukla & Lilly Ganju. (2010) Adjuvant effect of aqueous extract of Rhodiola imbricata rhizome on the immune responses to tetanus toxoid and ovalbumin in rats. Immunopharmacology and Immunotoxicology 32:1, pages 141-146.
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Shiv Rattan, Dinesh Kumar & Ashish R. Warghat. (2022) The influence of phenylalanine feeding on cell growth, antioxidant activity, phenylpropanoids content, and yield in cell suspension culture of Rhodiola imbricata (Edgew.). Plant Cell, Tissue and Organ Culture (PCTOC) 151:2, pages 347-359.
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Hao Fu, Yuzhi Zhang, Quan An, Dongdong Wang, Shiquan You, Dan Zhao, Jiachan Zhang, Changtao Wang & Meng Li. (2022) Anti-Photoaging Effect of Rhodiola rosea Fermented by Lactobacillus plantarum on UVA-Damaged Fibroblasts. Nutrients 14:11, pages 2324.
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Kuikui Chen, Jie Liu, Zhaochen Ma, Feipeng Duan, Zhonghui Guo & Hongbin Xiao. (2021) Rapid identification of chemical constituents of Rhodiola crenulata using liquid chromatography‐mass spectrometry pseudotargeted analysis . Journal of Separation Science 44:20, pages 3747-3776.
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Fei Han, Yanting Li, Xinjuan Mao, Rui Xu & Ran Yin. (2016) Characterization of chemical constituents in Rhodiola Crenulate by high-performance liquid chromatography coupled with Fourier-transform ion cyclotron resonance mass spectrometer (HPLC-FT-ICR MS). Journal of Mass Spectrometry 51:5, pages 363-368.
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Hsiu-Mei Chiang, Hsin-Chun Chen, Chin-Sheng Wu, Po-Yuan Wu & Kuo-Ching Wen. (2015) Rhodiola plants: Chemistry and biological activity. Journal of Food and Drug Analysis 23:3, pages 359-369.
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Alka Choudhary, Raj Kumar, Ravi Bihari Srivastava, Sunil Kumar Surapaneni, Kulbhushan Tikoo & Inder Pal Singh. (2015) Isolation and characterization of phenolic compounds from Rhodiola imbricata, a Trans-Himalayan food crop having antioxidant and anticancer potential. Journal of Functional Foods 16, pages 183-193.
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Chang-Won Cho, Chun-ji Han, Young Kyoung Rhee, Young-Chul Lee, Kwang-Soon Shin, Ji-Sun Shin, Kyung-Tae Lee & Hee-Do Hong. (2015) Cheonggukjang polysaccharides enhance immune activities and prevent cyclophosphamide-induced immunosuppression. International Journal of Biological Macromolecules 72, pages 519-525.
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Tao Guo. 2015. Dietary Chinese Herbs. Dietary Chinese Herbs 255 264 .
Long Li, Honghui Wang & Xin Zhao. (2014) Effects of Rhodiola on production, health and gut development of broilers reared at high altitude in Tibet. Scientific Reports 4:1.
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Ravichandran Senthilkumar, Rahul Chandran & Thangaraj Parimelazhagan. (2014) Hepatoprotective effect of Rhodiola imbricata rhizome against paracetamol-induced liver toxicity in rats. Saudi Journal of Biological Sciences 21:5, pages 409-416.
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Drishya Diwaker, K. P. Mishra, Lilly Ganju & S. B. Singh. (2014) Rhodiola inhibits dengue virus multiplication by inducing innate immune response genes RIG-I, MDA5 and ISG in human monocytes. Archives of Virology 159:8, pages 1975-1986.
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Xi Xu, Cheng Tan, Pingping Li, Shusong Zhang, Xuewen Pang, Hongju Liu, Li Li, Xiuyuan Sun, Yu Zhang, Hounan Wu, Xiaoping Chen & Qing Ge. (2013) Changes of Cytokines during a Spaceflight Analog - a 45-Day Head-Down Bed Rest. PLoS ONE 8:10, pages e77401.
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Rajkumar Tulsawani, Dharmendra Kumar Meena, Hem Shukla, Priyanka Sharma, Ram Niwas Meena, Vanita Gupta, Ratan Kumar, Harish Madan Divekar & Ramesh Chand Sawhney. (2011) Ninety days of repeated gavage administration of Rhodiola imbricata extract in rats . Journal of Applied Toxicology 33:5, pages 350-356.
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Amol B. Tayade, Priyanka Dhar, Jatinder Kumar, Manu Sharma, Rajinder S. Chauhan, Om P. Chaurasia & Ravi B. Srivastava. (2013) Chemometric Profile of Root Extracts of Rhodiola imbricata Edgew. with Hyphenated Gas Chromatography Mass Spectrometric Technique. PLoS ONE 8:1, pages e52797.
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Ravichandran Senthilkumar, Thangaraj Parimelazhagan, Om Prakash Chaurasia & R.B. Srivastava. (2013) Free radical scavenging property and antiproliferative activity of Rhodiola imbricata Edgew extracts in HT-29 human colon cancer cells. Asian Pacific Journal of Tropical Medicine 6:1, pages 11-19.
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Danjun Chen, Junting Fan, Peng Wang, Lanying Zhu, Yang Jin, Yan Peng & Shuhu Du. (2012) Isolation, identification and antioxidative capacity of water-soluble phenylpropanoid compounds from Rhodiola crenulata. Food Chemistry 134:4, pages 2126-2133.
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Ya-nan Yang, Zhao-zhen Liu, Zi-ming Feng, Jian-shuang Jiang & Pei-cheng Zhang. (2012) Lignans from the Root of Rhodiola crenulata . Journal of Agricultural and Food Chemistry 60:4, pages 964-972.
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Kelly Gauger & Sallie Schneider. 2010. Bioactive Foods and Extracts. Bioactive Foods and Extracts 37 47 .
Vanita Gupta, S.S. Lahiri, S. Sultana, R.K. Tulsawani & Ratan Kumar. (2010) Anti-oxidative effect of Rhodiola imbricata root extract in rats during cold, hypoxia and restraint (C–H–R) exposure and post-stress recovery. Food and Chemical Toxicology 48:4, pages 1019-1025.
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Raj Kumar, Kumar G. Phani & O.P. Chaurasia. (2010) In Vitro Antioxidant Activity Of Methanolic Extract Of Rhodiola Imbricata Edgew. Pharmacognosy Journal 2:7, pages 157-161.
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H.X. Li, S.C.W. Sze, Y. Tong & T.B. Ng. (2009) Production of Th1- and Th2-dependent cytokines induced by the Chinese medicine herb, Rhodiola algida, on human peripheral blood monocytes. Journal of Ethnopharmacology 123:2, pages 257-266.
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Vanita Gupta, S.S. Lahiri, S. Sultana & Ratan Kumar. (2009) Mechanism of action of Rhodiola imbricata Edgew during exposure to cold, hypoxia and restraint (C–H–R) stress induced hypothermia and post stress recovery in rats. Food and Chemical Toxicology 47:6, pages 1239-1245.
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Kamla P. Mishra, Lilly Ganju, Sudipta Chanda, Dev Karan & Ramesh C. Sawhney. (2009) Aqueous extract of Rhodiola imbricata rhizome stimulates Toll-like receptor 4, granzyme-B and Th1 cytokines in vitro. Immunobiology 214:1, pages 27-31.
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K. P. Mishra, S. Chanda, D. Karan, L. Ganju & R. C. Sawhney. (2008) Effect of Seabuckthorn ( Hippophae rhamnoides ) flavone on immune system: an in‐vitro approach . Phytotherapy Research 22:11, pages 1490-1495.
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V. Gupta, S. Saggu, R.K. Tulsawani, R.C. Sawhney & R. Kumar. (2008) A dose dependent adaptogenic and safety evaluation of Rhodiola imbricata Edgew, a high altitude rhizome. Food and Chemical Toxicology 46:5, pages 1645-1652.
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K.P. Mishra, Y.S. Padwad, A. Dutta, L. Ganju, M. Sairam, P.K. Banerjee & R.C. Sawhney. (2008) Aqueous extract of Rhodiola imbricata rhizome inhibits proliferation of an erythroleukemic cell line K-562 by inducing apoptosis and cell cycle arrest at G2/M phase. Immunobiology 213:2, pages 125-131.
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K.P. Mishra, L. Ganju, M. Sairam, P.K. Banerjee & R.C. Sawhney. (2008) A review of high throughput technology for the screening of natural products. Biomedicine & Pharmacotherapy 62:2, pages 94-98.
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