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ORIGINAL RESEARCH

The Role of Serum Inflammatory Markers in Acute Appendicitis and Their Success in Preventing Negative Laparotomy

, MD, , MD, , MD, , MD, , MD, , MD, , MD & , MD show all
Pages 345-352 | Received 03 May 2005, Accepted 21 Feb 2006, Published online: 09 Jul 2009

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Sandra Lorena de Oliveira Machado, Margarete Dulce Bagatini, Pauline da Costa, Jucimara Baldissarelli, Karine Paula Reichert, Lizielle Souza de Oliveira, Jéssica Gonçalves Lemos, Thiago Duarte, Maria Rosa Chitolina Schetinger & Vera Maria Morsch. (2016) Evaluation of mediators of oxidative stress and inflammation in patients with acute appendicitis. Biomarkers 21:6, pages 530-537.
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G. Frongia, A. Mehrabi, L. Ziebell, J.P. Schenk & P. Günther. (2016) Predicting Postoperative Complications After Pediatric Perforated Appendicitis. Journal of Investigative Surgery 29:4, pages 185-194.
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I. Richardsen, D.S. Schöb, T. F. Ulmer, G. Steinau, U. P. Neumann, C. D. Klink & A. Lambertz. (2016) Etiology of Appendicitis in Children: The Role of Bacterial and Viral Pathogens. Journal of Investigative Surgery 29:2, pages 74-79.
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Articles from other publishers (25)

Taher H. Elwan, Aimen Elsheikh Khalil Abdennour, Usama Akl, A. T. M. Elshennawy & Ibrahim M. Shatla. (2023) Unveiling the Role of Inflammatory Mediators and Gut Microbiome in Appendicitis: Types and Applications in Clinical Scoring. Advanced Gut & Microbiome Research 2023, pages 1-12.
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Jieun Byun, Seongkeun Park & Sook Min Hwang. (2023) Diagnostic Algorithm Based on Machine Learning to Predict Complicated Appendicitis in Children Using CT, Laboratory, and Clinical Features. Diagnostics 13:5, pages 923.
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Kubilay Gürünlüoglu, Gökmen Zararsiz, Mehmet Aslan, Sedat Akbas, Mehmet Tekin, Semra Gürünlüoglu, HarikaGözükara Bag, EcemSerbest Cin, Bengü Macit & Mehmet Demircan. (2023) Investigation of Serum Interleukin 6, High-Sensitivity C-Reactive Protein and White Blood Cell Levels during the Diagnosis and Treatment of Paediatric Appendicitis Patients Before and during the COVID-19 Pandemic. African Journal of Paediatric Surgery 20:2, pages 130.
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Nusrat S. Shommu, Jaime Blackwood, Craig N. Jenne, Ari R. Joffe, Dori-Ann Martin, Beata Mickiewicz, Mary Brindle, Robin Eccles, Hans J. Vogel & Graham C. Thompson. (2021) Metabolomics and Inflammatory Mediator Profiling for the Differentiation of Life-Threatening and Non-Severe Appendicitis in the Pediatric Population. Metabolites 11:10, pages 664.
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Ahmet ERTÜRK, Can ÖZTORUN, Süleyman Arif BOSTANCI, Gökhan DEMİRTAŞ, Rabia DEMİR, Doğuş GÜNEY, Emine YURT, Özcan EREL, Cüneyt KARAGÖL, Müjdem AZILI & Emrah ŞENEL. (2021) The role of thiol-disulfide and ischemia-modified albumin levels in the diagnosis of childhood appendicitis. Anatolian Current Medical Journal 3:3, pages 214-219.
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Toon Peeters, Sandrina Martens, Valentino D’Onofrio, Mark H. T. Stappers, Jeroen C. H. van der Hilst, Bert Houben, Ruth Achten, Leo A. B. Joosten & Inge C. Gyssens. (2020) An observational study of innate immune responses in patients with acute appendicitis. Scientific Reports 10:1.
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Mustafa Onur Oztan, Aysegul Aksoy Gokmen, Fatma Demet Arslan, Ebru Cakir, Ali Sayan, Elif Abay, Selçuk Kaya & Gokhan Koyluoglu. (2020) Diagnostic Value of Serum Urokinase-Type Plasminogen Activator Receptor in Children With Acute Appendicitis. Pediatric Emergency Care 36:7, pages 332-337.
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Sabri DEMİR, Yasemin DERE GÜNAL, İsmail ÖZMEN, Nermin DİNDAR BADEM, Salim NEŞELİOĞLU & Özcan EREL. (2020) Tiyol / Disülfit dengesinin değerlendirilmesi çocuklarda apandisitin ayırıcı tanısında yardımcı olabilir mi?. Turkish Journal of Pediatric Disease, pages 1-8.
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George Sakellaris, Dimitra Dimopoulou, Maria Niniraki, Anastasia Dimopoulou, Athanasios Alegakis, Emmanouil K. Symvoulakis, Dimitra Kostaki, Evangelos Blevrakis, Stavroula Kolivaki & Emmanouil Chryssos. (2020) The role of blood inflammatory markers in the diagnosis of appendicitis in children: a prospective study from a University Hospital in Greece. Gazzetta Medica Italiana Archivio per le Scienze Mediche 178:11.
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Nikola Stankovic, Maja Surbatovic, Ivan Stanojevic, Radoje Simić, Slavisa Djuricic, Maja Milickovic, Blagoje Grujic, Djordje Savic, Vesna Milojkovic Marinovic, Miona Stankovic & Danilo Vojvodic. (2019) Possible cytokine biomarkers in pediatric acute appendicitis. Italian Journal of Pediatrics 45:1.
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Serdar KIRMIZI, Muharrem KARAOĞLAN & Fuat İPEKÇİ. (2019) AKUT APANDİSİTLERDE AMELİYAT ÖNCESİ VE SONRASI CRP DEĞELERİNİN HİSTOPATOLOJİK BULGULARLA KARŞILAŞTIRILMASI. Bozok Tıp Dergisi.
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Burak Katipoglu, Ali Aygun & Hamza Çınar. (2019) The effect of appendix diameter on perforation in acute appendicitis cases. Cumhuriyet Medical Journal.
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S. Ali Naqvi, Graham C. Thompson, Ari R. Joffe, Jaime Blackwood, Dori-Ann Martin, Mary Brindle, Herman W. Barkema & Craig N. Jenne. (2019) Cytokines and Chemokines in Pediatric Appendicitis: A Multiplex Analysis of Inflammatory Protein Mediators. Mediators of Inflammation 2019, pages 1-13.
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Nusrat S. Shommu, Craig N. Jenne, Jaime Blackwood, Dori-Ann Martin, Ari R. Joffe, Robin Eccles, Mary Brindle, Ijab Khanafer, Hans J. Vogel & Graham C. Thompson. (2018) The Use of Metabolomics and Inflammatory Mediator Profiling Provides a Novel Approach to Identifying Pediatric Appendicitis in the Emergency Department. Scientific Reports 8:1.
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S.A. Kabir, S.I. Kabir, R. Sun, Sadaf Jafferbhoy & Ahmed Karim. (2017) How to diagnose an acutely inflamed appendix; a systematic review of the latest evidence. International Journal of Surgery 40, pages 155-162.
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Amish Acharya, Sheraz R. Markar, Melody Ni & George B. Hanna. (2016) Biomarkers of acute appendicitis: systematic review and cost–benefit trade-off analysis. Surgical Endoscopy 31:3, pages 1022-1031.
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Manne Andersson, Marie Rubér, Christina Ekerfelt, Hanna Björnsson Hallgren, Gunnar Olaison & Roland E. Andersson. (2014) Can New Inflammatory Markers Improve the Diagnosis of Acute Appendicitis?. World Journal of Surgery 38:11, pages 2777-2783.
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Ersin Gürkan Dumlu, Mehmet Tokaç, Birkan Bozkurt, Murat Baki Yildirim, Merve Ergin, Abdussamed Yalçin & Mehmet Kiliç. (2014) Correlation between the serum and tissue levels of oxidative stress markers and the extent of inflammation in acute appendicitis. Clinics 69:10, pages 677-682.
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Lauren Allister, Richard Bachur, Jonathan Glickman & Bruce Horwitz. (2011) Serum Markers in Acute Appendicitis. Journal of Surgical Research 168:1, pages 70-75.
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Arunjit S. Takhar, Meera Patel, Omer Al-Taan & James A. Stephenson. (2010) Acute Appendicitis. InnovAiT: Education and inspiration for general practice 4:4, pages 204-210.
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Astra Zviedre, Arnis Engelis, Mohit Kakar & Aigars Pētersons. (2011) Potential Role of Cytokines in Children with Acute Appendicitis and Acute Mesenteric Lymphadenitis. Acta Chirurgica Latviensis 11:1, pages 130-133.
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Ryszard Anielski, Beata Kuśnierz-Cabala & Krystyna Szafraniec. (2009) An evaluation of the utility of additional tests in the preoperative diagnostics of acute appendicitis. Langenbeck's Archives of Surgery 395:8, pages 1061-1068.
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Olivier Monneuse, S. Abdalla, F. Pilleul, V. Hervieu, L. Gruner, E. Tissot & X. Barth. (2009) Pain as the Only Consistent Sign of Acute Appendicitis: Lack of Inflammatory Signs Does Not Exclude the Diagnosis. World Journal of Surgery 34:2, pages 210-215.
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Shozo Yokoyama, Katsunari Takifuji, Tsukasa Hotta, Kenji Matsuda, Toru Nasu, Mikihito Nakamori, Naoki Hirabayashi, Hiroyuki Kinoshita & Hiroki Yamaue. (2009) C-Reactive protein is an independent surgical indication marker for appendicitis: a retrospective study. World Journal of Emergency Surgery 4:1.
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Peter Lopez & Amy De Rosa. 2009. Acute Care Surgery and Trauma. Acute Care Surgery and Trauma 307 315 .

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