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Original Research

Protective Effect of Cordycepin on Experimental Testicular Ischemia/Reperfusion Injury in Rats

, MD, , MD, , MD, , MD, , MD, , MD, & show all
Pages 1-8 | Received 05 Sep 2016, Accepted 04 Oct 2016, Published online: 12 Apr 2017

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Yu Zhang, Xiao Xi Zhang, Rui Yan Yuan, Tai Ren, Zi Yu Shao, Hong Fei Wang, Wei Long Cai, Li Tian Chen, Xu An Wang & Ping Wang. (2018) Cordycepin induces apoptosis in human pancreatic cancer cells via the mitochondrial-mediated intrinsic pathway and suppresses tumor growth in vivo. OncoTargets and Therapy 11, pages 4479-4490.
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Han Xu, Jing Cheng & Fei He. (2022) Cordycepin alleviates myocardial ischemia/reperfusion injury by enhancing autophagy via AMPK-mTOR pathway. Journal of Physiology and Biochemistry 78:2, pages 401-413.
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Ibrahim Aydogdu, Erkin Karaca, Ganime Coban, Ali Cay, Eray Metin Guler, Abdurrahim Kocyigit, Ersan Uzun, Yaren Ece Aydoğdu, Hüseyin Metin, Uygar Miçooğullari, Yusuf Ozlem Ilbey & Mehmet Zeynel Keskin. (2021) An investigation of the effects of amniotic fluid on experimental ischemia/reperfusion damage in rat testes. Journal of Pediatric Urology 17:6, pages 761.e1-761.e6.
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Houyou Yu, Xin Hong, Lihua Liu, Yangpeng Wu, Xuemei Xie, Guoxiang Fang & Shaomin Zhi. (2021) Cordycepin Decreases Ischemia/Reperfusion Injury in Diabetic Hearts via Upregulating AMPK/Mfn2-dependent Mitochondrial Fusion. Frontiers in Pharmacology 12.
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Shi Qi Zuo, Can Li, Yi Lun Liu, Yue Hao Tan, Xing Wan, Tian Xu, Qiang Li, Li Wang, Yong Li Wu, Feng Mei Deng & Bin Tang. (2021) Cordycepin inhibits cell senescence by ameliorating lysosomal dysfunction and inducing autophagy through the AMPK and mTOR–p70S6K pathway. FEBS Open Bio 11:10, pages 2705-2714.
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Masar Radhi, Sadaf Ashraf, Steven Lawrence, Asta Arendt Tranholm, Peter Arthur David Wellham, Abdul Hafeez, Ammar Sabah Khamis, Robert Thomas, Daniel McWilliams & Cornelia Huiberdina de Moor. (2021) A Systematic Review of the Biological Effects of Cordycepin. Molecules 26:19, pages 5886.
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Gulcin Ercan, Yuksel Altinel, Onur Olgac Karagulle, Hakan Yiğitbaş, Nadir Adnan Hacım, Serhat Meriç, Nihat Buğdaycı, Rumeysa Ilbar Tartar, Burcu Biltekin, Erkan Yavuz, Osman Bilgin Gulcicek, Ali Solmaz & Atilla Çelik. (2021) Cordycepin prevents the esophageal stricture formation in the alkali-burn rat model by exerting anti-inflammatory and antifibrotic effects. Acta Cirúrgica Brasileira 36:3.
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Hasan Riza Aydin, Cagri Akin Sekerci, Ertugrul Yigit, Hatice Kucuk, Huseyin Kocakgol, Seyfi Kartal, Yiloren Tanidir & Orhan Deger. (2020) Protective effect of cordycepin on experimental renal ischemia/reperfusion injury in rats. Archivio Italiano di Urologia e Andrologia 92:4.
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Esra Ekşi, Hatice Sonay Yalçın Cömert, Mustafa Imamoğlu, Ahmet Alver, Sevdegül Aydin Mungan & Haluk Sarıhan. (2020) Effects of myricetin on testicular torsion‐detorsion injury in rats. Andrologia 52:10.
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Si-Ming Wei, Rong-Yun Wang & Yan-Song Chen. (2020) Sesamol Protects Testis from Ischemia-Reperfusion Injury through Scavenging Reactive Oxygen Species and Upregulating CREM τ Expression . Oxidative Medicine and Cellular Longevity 2020, pages 1-9.
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Feng Han, Meng Dou, Yuxiang Wang, Cuixiang Xu, Yang Li, XiaoMing Ding, WuJun Xue, Jin Zheng, Puxun Tian & Chenguang Ding. (2020) Cordycepin protects renal ischemia/reperfusion injury through regulating inflammation, apoptosis, and oxidative stress. Acta Biochimica et Biophysica Sinica 52:2, pages 125-132.
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Ziwen Wang, Zelin Chen, Zhongyong Jiang, Peng Luo, Lang Liu, Yu Huang, Huilan Wang, Yu Wang, Lei Long, Xu Tan, Dengqun Liu, Taotao Jin, Yawei Wang, Yang Wang, Fengying Liao, Chi Zhang, Long Chen, Yibo Gan, Yunsheng Liu, Fan Yang, Chunji Huang, Hongming Miao, Jieping Chen, Tianmin Cheng, Xiaobing Fu & Chunmeng Shi. (2019) Cordycepin prevents radiation ulcer by inhibiting cell senescence via NRF2 and AMPK in rodents. Nature Communications 10:1.
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Dong Liu, Liqun Xu, Xiaoyan Zhang, Changhong Shi, Shubin Qiao, Zhiqiang Ma & Jiansong Yuan. (2019) Snapshot: Implications for mTOR in Aging-related Ischemia/Reperfusion Injury. Aging and disease 10:1, pages 116.
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Zhiqiang Ma, Zhenlong Xin, Wencheng Di, Xiaolong Yan, Xiaofei Li, Russel J. Reiter & Yang Yang. (2017) Melatonin and mitochondrial function during ischemia/reperfusion injury. Cellular and Molecular Life Sciences 74:21, pages 3989-3998.
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