Publication Cover
Inhalation Toxicology
International Forum for Respiratory Research
Volume 12, 2000 - Issue 1-2
377
Views
133
CrossRef citations to date
0
Altmetric
Research Article

THE RELEVANCE OF THE RAT LUNG RESPONSE TO PARTICLE OVERLOAD FOR HUMAN RISK ASSESSMENT: A Workshop Consensus Report

Pages 1-17 | Published online: 01 Oct 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (35)

Jody Morgan, Robin Bell & Alison L. Jones. (2020) Endogenous doesn’t always mean innocuous: a scoping review of iron toxicity by inhalation. Journal of Toxicology and Environmental Health, Part B 23:3, pages 107-136.
Read now
Kevin E. Driscoll & Paul J. A. Borm. (2020) Expert workshop on the hazards and risks of poorly soluble low toxicity particles. Inhalation Toxicology 32:2, pages 53-62.
Read now
Ishrat Chaudhuri, Claudia Fruijtier-Pölloth, Yufanyi Ngiewih & Len Levy. (2018) Evaluating the evidence on genotoxicity and reproductive toxicity of carbon black: a critical review. Critical Reviews in Toxicology 48:2, pages 143-169.
Read now
Phoebe A. Stapleton, Cody E. Nichols, Jinghai Yi, Carroll R. McBride, Valerie C. Minarchick, Danielle L. Shepherd, John M. Hollander & Timothy R. Nurkiewicz. (2015) Microvascular and mitochondrial dysfunction in the female F1 generation after gestational TiO2 nanoparticle exposure. Nanotoxicology 9:8, pages 941-951.
Read now
Günter Oberdörster, Vincent Castranova, Bahman Asgharian & Phil Sayre. (2015) Inhalation Exposure to Carbon Nanotubes (CNT) and Carbon Nanofibers (CNF): Methodology and Dosimetry. Journal of Toxicology and Environmental Health, Part B 18:3-4, pages 121-212.
Read now
Calvin C. Willhite, Nataliya A. Karyakina, Robert A. Yokel, Nagarajkumar Yenugadhati, Thomas M. Wisniewski, Ian M.F. Arnold, Franco Momoli & Daniel Krewski. (2014) Systematic review of potential health risks posed by pharmaceutical, occupational and consumer exposures to metallic and nanoscale aluminum, aluminum oxides, aluminum hydroxide and its soluble salts. Critical Reviews in Toxicology 44:sup4, pages 1-80.
Read now
Brooke T. Mossman & Robert E. Glenn. (2013) Bioreactivity of the crystalline silica polymorphs, quartz and cristobalite, and implications for occupational exposure limits (OELs). Critical Reviews in Toxicology 43:8, pages 632-660.
Read now
Ernst M. Bomhard, Heinz-Peter Gelbke, Hermann Schenk, Gary M. Williams & Samuel M. Cohen. (2013) Evaluation of the carcinogenicity of gallium arsenide. Critical Reviews in Toxicology 43:5, pages 436-466.
Read now
Peter Møller, Pernille Høgh Danielsen, Kim Jantzen, Martin Roursgaard & Steffen Loft. (2013) Oxidatively damaged DNA in animals exposed to particles. Critical Reviews in Toxicology 43:2, pages 96-118.
Read now
Angelika Kolling, Heinrich Ernst, Susanne Rittinghausen & Uwe Heinrich. (2011) Relationship of pulmonary toxicity and carcinogenicity of fine and ultrafine granular dusts in a rat bioassay. Inhalation Toxicology 23:9, pages 544-554.
Read now
Jitendra Gangwar, Tarun Gupta, Sudhir Gupta & Avinash K. Agarwal. (2011) Emissions from diesel versus biodiesel fuel used in a CRDI SUV engine: PM mass and chemical composition. Inhalation Toxicology 23:8, pages 449-458.
Read now
Brooke T. Mossman$suffix/text()$suffix/text(), Morton Lippmann, Thomas W. Hesterberg, Karl T. Kelsey, Aaron Barchowsky & James C. Bonner. (2011) Pulmonary Endpoints (Lung Carcinomas and Asbestosis) Following Inhalation Exposure to Asbestos. Journal of Toxicology and Environmental Health, Part B 14:1-4, pages 76-121.
Read now
Maureen R. Gwinn, Stephen S. Leonard, Linda M. Sargent, David T. Lowry, Kimberly McKinstry, Terry Meighan, Steve H. Reynolds, Michael Kashon, Vince Castranova & Val Vallyathan. (2009) The Role of p53 in Silica-Induced Cellular and Molecular Responses Associated with Carcinogenesis. Journal of Toxicology and Environmental Health, Part A 72:23, pages 1509-1519.
Read now
Amy K. Madl & Kent E. Pinkerton. (2009) Health effects of inhaled engineered and incidental nanoparticles. Critical Reviews in Toxicology 39:8, pages 629-658.
Read now
Yasuo Morimoto, Masami Hirohashi, Takahiko Kasai, Takako Oyabu, Akira Ogami, Toshihiko Myojo, Masahiro Murakami, Ken-ichiro Nishi, Chikara Kadoya, Motoi Todoroki, Makoto Yamamoto, Kazuaki Kawai, Hiroshi Kasai & Isamu Tanaka. (2009) Effect of polymerized toner on rat lung in chronic inhalation study. Inhalation Toxicology 21:11, pages 898-905.
Read now
D. M. Hollins, M. A. McKinley, C. Williams, A. Wiman, D. Fillos, P. S. Chapman & A. K. Madl. (2009) Beryllium and lung cancer: A weight of evidence evaluation of the toxicological and epidemiological literature. Critical Reviews in Toxicology 39:sup1, pages 1-32.
Read now
AmyK. Madl, EllenP. Donovan, ShannonH. Gaffney, MegA. McKinley, EmilyC. Moody, JohnL. Henshaw & DennisJ. Paustenbach. (2008) State-of-the-Science Review of the Occupational Health Hazards of Crystalline Silica in Abrasive Blasting Operations and Related Requirements for Respiratory Protection. Journal of Toxicology and Environmental Health, Part B 11:7, pages 548-608.
Read now
GaryL. Ginsberg, Bahman Asgharian, JuliaS. Kimbell, JamesS. Ultman & AnnieM. Jarabek. (2007) Modeling Approaches for Estimating the Dosimetry of Inhaled Toxicants in Children. Journal of Toxicology and Environmental Health, Part A 71:3, pages 166-195.
Read now
Lorenz R. Rhomberg, Karl Baetcke, Jerry Blancato, James Bus, Samuel Cohen, Rory Conolly, Rakesh Dixit, John Doe, Karen Ekelman, Penny Fenner-Crisp, Paul Harvey, Dale Hattis, Abigail Jacobs, David Jacobson-Kram, Tom Lewandowski, Robert Liteplo, Olavi Pelkonen, Jerry Rice, Diana Somers, Angelo Turturro, Webster West & Stephen Olin. (2007) Issues in the Design and Interpretation of Chronic Toxicity and Carcinogenicity Studies in Rodents: Approaches to Dose Selection. Critical Reviews in Toxicology 37:9, pages 729-837.
Read now
Gerhard J. Nohynek, Jürgen Lademann, Christele Ribaud & Michael S. Roberts. (2007) Grey Goo on the Skin? Nanotechnology, Cosmetic and Sunscreen Safety. Critical Reviews in Toxicology 37:3, pages 251-277.
Read now
Charles Ris. (2007) U.S. EPA Health Assessment for Diesel Engine Exhaust: A Review. Inhalation Toxicology 19:sup1, pages 229-239.
Read now
David Dankovic, Eileen Kuempel & Matthew Wheeler. (2007) An Approach to Risk Assessment for TiO2. Inhalation Toxicology 19:sup1, pages 205-212.
Read now
Helmut Greim & Kyriakoula Ziegler-Skylakakis. (2007) Risk Assessment for Biopersistent Granular Particles. Inhalation Toxicology 19:sup1, pages 199-204.
Read now
Catrin Albrecht, Doris Höhr, Petra Haberzettl, Andrea Becker, Paul J. A. Borm & Roel P. F. Schins. (2007) Surface-Dependent Quartz Uptake by Macrophages: Potential Role in Pulmonary Inflammation and Lung Clearance. Inhalation Toxicology 19:sup1, pages 39-48.
Read now
Eileen D. Kuempel, Lang Tran, Vincent Castranova & A. John Bailer. (2007) Response to Dr. Morfeld's Letter. Inhalation Toxicology 19:2, pages 197-198.
Read now
Thomas W. Hesterberg, William B. Bunn III, Gerald R. Chase, Peter A. Valberg, Thomas J. Slavin, Charles A. Lapin & Georgia A. Hart. (2006) A Critical Assessment of Studies on the Carcinogenic Potential of Diesel Exhaust. Critical Reviews in Toxicology 36:9, pages 727-776.
Read now
E. D. Kuempel, C. L. Tran, V. Castranova & A. J. Bailer. (2006) Lung Dosimetry and Risk Assessment of Nanoparticles: Evaluating and Extending Current Models in Rats and Humans. Inhalation Toxicology 18:10, pages 717-724.
Read now
Klaus Rödelsperger & Bernd Brückel. (2006) The Carcinogenicity of WHO Fibers of Silicon Carbide: SiC Whiskers Compared to Cleavage Fragments of Granular SiC. Inhalation Toxicology 18:9, pages 623-631.
Read now
Ann Hubbs, Mark Greskevitch, Eileen Kuempel, Fernando Suarez & Mark Toraason. (2005) Abrasive Blasting Agents: Designing Studies to Evaluate Relative Risk. Journal of Toxicology and Environmental Health, Part A 68:11-12, pages 999-1016.
Read now
Annie M. Jarabek, Bahman Asgharian & Frederick J. Miller. (2005) Dosimetric Adjustments for Interspecies Extrapolation of Inhaled Poorly Soluble Particles (PSP). Inhalation Toxicology 17:7-8, pages 317-334.
Read now
William B. Bunn$suffix/text()$suffix/text(), Thomas W. Hesterberg, Peter A. Valberg, Thomas J. Slavin, Georgia Hart & Charles A. Lapin. (2004) A Reevaluation of the Literature Regarding the Health Assessment of Diesel Engine Exhaust. Inhalation Toxicology 16:14, pages 889-900.
Read now
D.B. Warheit, G.A. Hart, T.W. Hesterberg, J.J. Collins, W.M. Dyer, G.M.H. Swaen, V. Castranova, A.I. Soiefer & G.L. Kennedy. (2001) Potential Pulmonary Effects of Man-Made Organic Fiber (MMOF) Dusts. Critical Reviews in Toxicology 31:6, pages 697-736.
Read now
Catrin Albrecht, Brigitte Adolf, Christel Weishaupt, Doris Höhr, Isabel Zeitträger, Johannes Friemann, Paul J. A. Borm. (2001) Clara-Cell Hyperplasia After Quartz and Coal-Dust Instillation in Rat Lung. Inhalation Toxicology 13:3, pages 191-205.
Read now

Articles from other publishers (98)

Xing Zhang, Yuanyuan Song, Hongyang Gong, Chunyan Wu, Binquan Wang, Wenxuan Chen, Jiawei Hu, Hanhui Xiang, Ke Zhang & Mingkuan Sun. (2023) Neurotoxicity of Titanium Dioxide Nanoparticles: A Comprehensive Review. International Journal of Nanomedicine Volume 18, pages 7183-7204.
Crossref
Jalal Poostforooshan, Sabrina Belbekhouche, Vinzent Olszok, Malte F. B. Stodt, Mira Simmler, Malte Bierwirth, Hermann Nirschl, Johannes Kiefer, Udo Fritsching & Alfred P. Weber. (2023) Synthesis of Pure and Fe-Doped TiO 2 Nanoparticles via Electrospray-Assisted Flame Spray Pyrolysis for Antimicrobial Applications . ACS Applied Nano Materials.
Crossref
Motoki Hojo, Ai Maeno, Yoshimitsu Sakamoto, Yukio Yamamoto, Yuhji Taquahashi, Akihiko Hirose, Jin Suzuki, Akiko Inomata & Dai Nakae. (2023) Time-Course of Transcriptomic Change in the Lungs of F344 Rats Repeatedly Exposed to a Multiwalled Carbon Nanotube in a 2-Year Test. Nanomaterials 13:14, pages 2105.
Crossref
Robert J. McCunney, Len Levy, Ishrat Chaudhuri, Yufanyi Ngiewih, Mei Yong & Wesley Wampler. 2003. Patty's Toxicology. Patty's Toxicology 1 25 .
Carlos Wells, Marta Pogribna, Beverly Lyn‐Cook & George Hammons. 2023. Impact of Engineered Nanomaterials in Genomics and Epigenomics. Impact of Engineered Nanomaterials in Genomics and Epigenomics 145 186 .
Guofang Zhang, Wenhe Luo, Wenjie Yang, Su Li, Dongjie Li, Yanqiao Zeng & Yang Li. (2022) The importance of the IL ‐1 family of cytokines in nanoimmunosafety and nanotoxicology . WIREs Nanomedicine and Nanobiotechnology 14:6.
Crossref
Afsheen Mansoor, Zohaib Khurshid, Muhammad Talal Khan, Emaan Mansoor, Faaz Ahmad Butt, Asif Jamal & Paulo J. Palma. (2022) Medical and Dental Applications of Titania Nanoparticles: An Overview. Nanomaterials 12:20, pages 3670.
Crossref
Heather N. Lynch, Daniel J. Lauer, William J. Thompson, Olivia Leleck, Rachel D. Freid, Justin Collins, Kathleen Chen, A. Michael Ierardi, Ania M. Urban, Michael A. Cappello, Paolo Boffetta & Kenneth A. Mundt. (2022) Systematic review of the scientific evidence of the pulmonary carcinogenicity of talc. Frontiers in Public Health 10.
Crossref
Kenneth A. Mundt, Annette B. Santamaria, William J. Thompson, Christopher A. Bates, Corey Boles, G. Scott Dotson & Mei Yong. (2022) Carcinogenicity of Poorly Soluble Low Toxicity Particles: Commentary on Epidemiology as a Risk Assessment “Reality Check”. Frontiers in Public Health 10.
Crossref
Emilio Di Ianni, Nicklas Raun Jacobsen, Ulla Birgitte Vogel & Peter Møller. (2022) Systematic review on primary and secondary genotoxicity of carbon black nanoparticles in mammalian cells and animals. Mutation Research/Reviews in Mutation Research 790, pages 108441.
Crossref
Maaike Visser, Ilse Gosens, Delphine Bard, Pieter van Broekhuizen, Gemma Janer, Eileen Kuempel, Michael Riediker, Ulla Vogel & Susan Dekkers. (2022) Towards health-based nano reference values (HNRVs) for occupational exposure: Recommendations from an expert panel. NanoImpact 26, pages 100396.
Crossref
Gregory S. Ladics, Owen Price, Shantanu Kelkar, Scott Herkimer & Shawn Anderson. (2021) A Weight-of-the-Evidence Approach for Evaluating, in Lieu of Animal Studies, the Potential of a Novel Polysaccharide Polymer to Produce Lung Overload. Chemical Research in Toxicology 34:6, pages 1430-1444.
Crossref
Neeraj Kumar Yadav, Mohit Raj Saxena & Rakesh Kumar Maurya. A Review of Toxicity Analysis of Particulate Emissions from Conventional and Low-Temperature Combustion Engines. A Review of Toxicity Analysis of Particulate Emissions from Conventional and Low-Temperature Combustion Engines.
Calvin C. Willhite, Nataliya A. Karyakina, Eirik Nordheim, Ian Arnold, Vic Armstrong, Franco Momoli, Natalia S. Shilnikova, Nagarajkumar Yenugadhati & Daniel Krewski. (2021) The REACH registration process: A case study of metallic aluminium, aluminium oxide and aluminium hydroxide. NeuroToxicology 83, pages 166-178.
Crossref
Hedwig M. BraakhuisIlse GosensMinne B. Heringa, Agnes G. OomenRob J. VandebrielMonique GroenewoldFlemming R. Cassee. (2021) Mechanism of Action of TiO 2 : Recommendations to Reduce Uncertainties Related to Carcinogenic Potential . Annual Review of Pharmacology and Toxicology 61:1, pages 203-223.
Crossref
Zhangjian Chen, Shuo Han, Shupei Zhou, Huimin Feng, Ying Liu & Guang Jia. (2020) Review of health safety aspects of titanium dioxide nanoparticles in food application. NanoImpact 18, pages 100224.
Crossref
Alessia Flaccavento, Roberta Pecoraro, Elena Maria Scalisi, Giuseppina Messina, Antonio Salvaggio, Giuliana Impellizzeri, Bianca Maria Lombardo & Maria Violetta Brundo. (2019) Morphostructural and immunohistochemical study for evaluation of nano‐TiO 2 toxicity in Armadillo officinalis Duméril, 1816 (Crustacea, Isopoda, Oniscidea) . Microscopy Research and Technique 83:3, pages 297-303.
Crossref
Zhilei Mao, Shushu Li, Lina Zhang, Mengmeng Yao, Zhu Zhou & Minjian Chen. (2019) The mTOR/GCLc/GSH Pathway Mediates the Dose-Dependent Bidirectional Regulation of ROS Induced by TiO 2 NPs in Neurogenic Cells . Oxidative Medicine and Cellular Longevity 2019, pages 1-14.
Crossref
Zuzana Skubalova, Hana Michalkova, Petr Michalek, Vladislav Strmiska, Roman Guran, Miguel Angel Merlos Rodrigo, Klara Castkova, David Hynek, Vladimir Pekarik, Ondrej Zitka, Vojtech Adam & Zbynek Heger. (2019) Prevalent anatase crystalline phase increases the cytotoxicity of biphasic titanium dioxide nanoparticles in mammalian cells. Colloids and Surfaces B: Biointerfaces 182, pages 110391.
Crossref
Sriram Prasath & Kavitha Palaniappan. (2019) Is using nanosilver mattresses/pillows safe? A review of potential health implications of silver nanoparticles on human health. Environmental Geochemistry and Health 41:5, pages 2295-2313.
Crossref
Satomi Kawai, Masanori Niwano & Masayuki Sato. (2019) A risk assessment framework for self-management of poorly soluble low toxic nanomaterials. Heliyon 5:8, pages e02165.
Crossref
Wenli Li & Juergen Pauluhn. (2018) Re-defining kinetic lung overload: Time for new paradigms. Toxicology Letters 295, pages 212-219.
Crossref
P.A. Schulte, E.D. Kuempel & N.M. Drew. (2018) Characterizing risk assessments for the development of occupational exposure limits for engineered nanomaterials. Regulatory Toxicology and Pharmacology 95, pages 207-219.
Crossref
Maria Violetta Brundo & Antonio Salvaggio. 2018. Recent Advances in Zebrafish Researches. Recent Advances in Zebrafish Researches.
Aziemah Zulkifli, Emilia Zainal Abidin, Najihah Zainol Abidin, Amer Siddiq Amer Nordin, Sarva Mangala Praveena, Sharifah Norkhadijah Syed Ismail, Irniza Rasdi, Karmegam Karuppiah & Anita Abd Rahman. (2018) Electronic cigarettes: a systematic review of available studies on health risk assessment. Reviews on Environmental Health 33:1, pages 43-52.
Crossref
Nathan M. Drew, Eileen D. Kuempel, Ying Pei & Feng Yang. (2017) A quantitative framework to group nanoscale and microscale particles by hazard potency to derive occupational exposure limits: Proof of concept evaluation. Regulatory Toxicology and Pharmacology 89, pages 253-267.
Crossref
Juergen Pauluhn. (2017) Kinetic modeling of the retention and fate of inhaled cerium oxide nanoparticles in rats: The cumulative displacement volume of agglomerates determines the outcome. Regulatory Toxicology and Pharmacology 86, pages 319-331.
Crossref
D.B. Warheit, R. Kreiling & L.S. Levy. (2016) Relevance of the rat lung tumor response to particle overload for human risk assessment—Update and interpretation of new data since ILSI 2000. Toxicology 374, pages 42-59.
Crossref
M.M. Bhatti, A. Zeeshan & R. Ellahi. (2016) Endoscope analysis on peristaltic blood flow of Sisko fluid with Titanium magneto-nanoparticles. Computers in Biology and Medicine 78, pages 29-41.
Crossref
Chad M. Thompson, Mina Suh, Liz Mittal, Daniele S. Wikoff, Brian Welsh & Deborah M. Proctor. (2016) Development of linear and threshold no significant risk levels for inhalation exposure to titanium dioxide using systematic review and mode of action considerations. Regulatory Toxicology and Pharmacology 80, pages 60-70.
Crossref
Maria V. Brundo, Roberta Pecoraro, Fabio Marino, Antonio Salvaggio, Daniele Tibullo, Salvatore Saccone, Vincenzo Bramanti, Maria A. Buccheri, Giuliana Impellizzeri, Viviana Scuderi, Massimo Zimbone & Vittorio Privitera. (2016) Toxicity Evaluation of New Engineered Nanomaterials in Zebrafish. Frontiers in Physiology 7.
Crossref
Camilla PeaseThomas Rücker & Thomas Birk. (2016) Review of the Evidence from Epidemiology, Toxicology, and Lung Bioavailability on the Carcinogenicity of Inhaled Iron Oxide Particulates. Chemical Research in Toxicology 29:3, pages 237-254.
Crossref
Brian C. Sayers, Nigel J. Walker, Joseph H. Roycroft, Dori R. Germolec, Gregory L. Baker, Mark L. Clark, Barry K. Hayden, Henry DeFord, Jeffrey A. Dill, Amit Gupta & Matthew D. Stout. (2016) Lung deposition and clearance of microparticle and nanoparticle C60 fullerene aggregates in B6C3F1 mice and Wistar Han rats following nose-only inhalation for 13 weeks. Toxicology 339, pages 87-96.
Crossref
Eileen D. Kuempel & Vincent Castranova. 2016. Assessing Nanoparticle Risks to Human Health. Assessing Nanoparticle Risks to Human Health 45 82 .
Elena Maser, Markus Schulz, Ursula G. Sauer, Martin Wiemann, Lan Ma-Hock, Wendel Wohlleben, Andrea Hartwig & Robert Landsiedel. (2015) In vitro and in vivo genotoxicity investigations of differently sized amorphous SiO2 nanomaterials. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 794, pages 57-74.
Crossref
David B. Warheit & E. Maria Donner. (2015) Risk assessment strategies for nanoscale and fine-sized titanium dioxide particles: Recognizing hazard and exposure issues. Food and Chemical Toxicology 85, pages 138-147.
Crossref
Monice M. Fiume, Ivan Boyer, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James G. MarksJrJr, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder & F. Alan Andersen. (2015) Safety Assessment of Talc as Used in Cosmetics. International Journal of Toxicology 34:1_suppl, pages 66S-129S.
Crossref
Konstantinos Farsalinos, Vassilis Voudris & Konstantinos Poulas. (2015) Are Metals Emitted from Electronic Cigarettes a Reason for Health Concern? A Risk-Assessment Analysis of Currently Available Literature. International Journal of Environmental Research and Public Health 12:5, pages 5215-5232.
Crossref
J. Michael Berg, Phillip T. Goad & Thomas W. Hesterberg. 2015. Hamilton & Hardy's Industrial Toxicology. Hamilton & Hardy's Industrial Toxicology 1301 1310 .
Andrea L. Armstead, Valerie C. Minarchick, Dale W. Porter, Timothy R. Nurkiewicz & Bingyun Li. (2015) Acute Inflammatory Responses of Nanoparticles in an Intra-Tracheal Instillation Rat Model. PLOS ONE 10:3, pages e0118778.
Crossref
Sabina Halappanavar, Anne Thoustrup Saber, Nathalie Decan, Keld Alstrup Jensen, Dongmei Wu, Nicklas Raun Jacobsen, Charles Guo, Jacob Rogowski, Ismo K. Koponen, Marcus Levin, Anne Mette Madsen, Rambabu Atluri, Valentinas Snitka, Renie K. Birkedal, David Rickerby, Andrew Williams, Håkan Wallin, Carole L. Yauk & Ulla Vogel. (2015) Transcriptional profiling identifies physicochemical properties of nanomaterials that are determinants of the in vivo pulmonary response. Environmental and Molecular Mutagenesis 56:2, pages 245-264.
Crossref
. (2014) Human and Animal Evidence Supports Lower Occupational Exposure Limits for Poorly-Soluble Respirable Particles<subtitle>Letter to the Editor re: ‘Low-Toxicity Dusts: Current Exposure Guidelines Are Not Sufficiently Protective’ by Cherrie, Brosseau, Hay and Donaldson</subtitle>. The Annals of Occupational Hygiene.
Crossref
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 78 .
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 93 .
Alokita Karmakar, Qinli Zhang & Yongbin Zhang. (2014) Neurotoxicity of nanoscale materials. Journal of Food and Drug Analysis 22:1, pages 147-160.
Crossref
Harri Alenius, Julia Catalán, Hanna Lindberg, Hannu Norppa, Jaana Palomäki & Kai Savolainen. 2014. Handbook of Nanosafety. Handbook of Nanosafety 59 133 .
T.N. Perkins, P.M. Peeters, E.F.M. Wouters, N.L. Reynaert & B.T. Mossman. 2014. Pathobiology of Human Disease. Pathobiology of Human Disease 2654 2664 .
Makoto Ema, Masato Naya, Masao Horimoto & Haruhisa Kato. (2013) Developmental toxicity of diesel exhaust: A review of studies in experimental animals. Reproductive Toxicology 42, pages 1-17.
Crossref
Eleonore Fröhlich, Birgit Johanna Teubl & Eva Roblegg. (2013) Titanium dioxide nanoparticles and the oral uptake-route. BioNanoMaterials 14:1-2, pages 25-35.
Crossref
David B. Warheit. (2013) How to measure hazards/risks following exposures to nanoscale or pigment-grade titanium dioxide particles. Toxicology Letters 220:2, pages 193-204.
Crossref
Jürgen Pauluhn. 2013. Nanomaterials. Nanomaterials 68 83 .
Ann F. Hubbs, Linda M. Sargent, Dale W. Porter, Tina M. Sager, Bean T. Chen, David G. Frazer, Vincent Castranova, Krishnan Sriram, Timothy R. Nurkiewicz, Steven H. Reynolds, Lori A. Battelli, Diane Schwegler-Berry, Walter McKinney, Kara L. Fluharty & Robert R. Mercer. (2013) Nanotechnology: Toxicologic Pathology. Toxicologic Pathology 41:2, pages 395-409.
Crossref
Ann Hubbs, Dale W. Porter, Robert Mercer, Vincent Castranova, Linda Sargent & Krishnan Sriram. 2013. Haschek and Rousseaux's Handbook of Toxicologic Pathology. Haschek and Rousseaux's Handbook of Toxicologic Pathology 1373 1419 .
Robert J. McCunney, Henry J. Muranko, Chris M. Long, Ali K. Hamade, Peter A. Valberg & Peter Morfeld. 2003. Patty's Toxicology. Patty's Toxicology 429 454 .
Roger O. McClellan, Thomas W. Hesterberg & John C. Wall. (2012) Evaluation of carcinogenic hazard of diesel engine exhaust needs to consider revolutionary changes in diesel technology. Regulatory Toxicology and Pharmacology 63:2, pages 225-258.
Crossref
Robert Landsiedel, Lan Ma-Hock, Hans-Juergen Haussmann, Ben van Ravenzwaay, Martin Kayser & Karin Wiench. (2012) Inhalation studies for the safety assessment of nanomaterials: status quo and the way forward. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 4:4, pages 399-413.
Crossref
Sarah X.L. HuangMichael A. Partridge, Shanaz A. Ghandhi, Mercy M. Davidson, Sally A. Amundson & Tom K. Hei. (2012) Mitochondria-Derived Reactive Intermediate Species Mediate Asbestos-Induced Genotoxicity and Oxidative Stress–Responsive Signaling Pathways. Environmental Health Perspectives 120:6, pages 840-847.
Crossref
Hanna K. Lindberg, Ghita C.-M. Falck, Julia Catalán, Antti J. Koivisto, Satu Suhonen, Hilkka Järventaus, Elina M. Rossi, Heli Nykäsenoja, Yrjö Peltonen, Carlos Moreno, Harri Alenius, Timo Tuomi, Kai M. Savolainen & Hannu Norppa. (2012) Genotoxicity of inhaled nanosized TiO2 in mice. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 745:1-2, pages 58-64.
Crossref
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 80 .
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 36 .
Ivo Iavicoli, Veruscka Leso & Antonio Bergamaschi. (2012) Toxicological Effects of Titanium Dioxide Nanoparticles: A Review of In Vivo Studies . Journal of Nanomaterials 2012, pages 1-36.
Crossref
Peter Greaves. 2012. Histopathology of Preclinical Toxicity Studies. Histopathology of Preclinical Toxicity Studies 207 261 .
Ken Donaldson & Craig A. Poland. 2012. Adverse Effects of Engineered Nanomaterials. Adverse Effects of Engineered Nanomaterials 121 137 .
H. Rothe, R. Fautz, E. Gerber, L. Neumann, K. Rettinger, W. Schuh & C. Gronewold. (2011) Special aspects of cosmetic spray safety evaluations: Principles on inhalation risk assessment. Toxicology Letters 205:2, pages 97-104.
Crossref
Avinash Kumar Agarwal, Tarun Gupta & Abhishek Kothari. (2011) Particulate emissions from biodiesel vs diesel fuelled compression ignition engine. Renewable and Sustainable Energy Reviews 15:6, pages 3278-3300.
Crossref
Vincent Castranova. 2011. Aerosol Measurement. Aerosol Measurement 793 803 .
Jiegou Xu, Yoko Sagawa, Mitsuru Futakuchi, Katsumi Fukamachi, David B. Alexander, Fumio Furukawa, Yoshiaki Ikarashi, Tadashi Uchino, Tetsuji Nishimura, Akimichi Morita, Masumi Suzui & Hiroyuki Tsuda. (2011) Lack of promoting effect of titanium dioxide particles on ultraviolet B-initiated skin carcinogenesis in rats. Food and Chemical Toxicology 49:6, pages 1298-1302.
Crossref
Osamu YAMAMOTO. (2011) Biologocal Effects of Industrial Nanomaterials (the first part). Nishi Nihon Hifuka 73:4, pages 392-401.
Crossref
. (2010) Beryllium Metal II. A Review of the Available Toxicity Data. The Annals of Occupational Hygiene.
Crossref
Jürgen Pauluhn. (2011) Poorly soluble particulates: Searching for a unifying denominator of nanoparticles and fine particles for DNEL estimation. Toxicology 279:1-3, pages 176-188.
Crossref
Eileen Kuempel & Vincent Castranova. 2011. Assessing Nanoparticle Risks to Human Health. Assessing Nanoparticle Risks to Human Health 65 97 .
Naohide Shinohara, Tetsuya Nakazato, Moritaka Tamura, Shigehisa Endoh, Hiroko Fukui, Yasuo Morimoto, Toshihiko Myojo, Manabu Shimada, Kazuhiro Yamamoto, Hiroaki Tao, Yasukazu Yoshida & Junko Nakanishi. (2010) Clearance Kinetics of Fullerene C60 Nanoparticles from Rat Lungs after Intratracheal C60 Instillation and Inhalation C60 Exposure. Toxicological Sciences 118:2, pages 564-573.
Crossref
Amir S. Yazdi, Greta Guarda, Nicolas Riteau, Stefan K. Drexler, Aubry Tardivel, Isabelle Couillin & Jürg Tschopp. (2010) Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1β. Proceedings of the National Academy of Sciences 107:45, pages 19449-19454.
Crossref
Robert A. Howd & Anna M. Fan. 2010. Cancer Risk Assessment. Cancer Risk Assessment 66 95 .
Yin‐Tak Woo & David Y. Lai. 2010. Cancer Risk Assessment. Cancer Risk Assessment 515 556 .
Jürgen Pauluhn. (2010) Multi-walled carbon nanotubes (Baytubes®): Approach for derivation of occupational exposure limit. Regulatory Toxicology and Pharmacology 57:1, pages 78-89.
Crossref
Jürgen Pauluhn. (2010) Subchronic 13-Week Inhalation Exposure of Rats to Multiwalled Carbon Nanotubes: Toxic Effects Are Determined by Density of Agglomerate Structures, Not Fibrillar Structures. Toxicological Sciences 113:1, pages 226-242.
Crossref
Sang‐Hee Jeong, Wan‐Seob Cho, Ji‐Eun Kim & Myung‐Haing Cho. 2009. General, Applied and Systems Toxicology. General, Applied and Systems Toxicology.
P.A. Valberg, J. Bruch & R.J. McCunney. (2009) Are rat results from intratracheal instillation of 19 granular dusts a reliable basis for predicting cancer risk?. Regulatory Toxicology and Pharmacology 54:1, pages 72-83.
Crossref
Jürgen Pauluhn. (2009) Pulmonary Toxicity and Fate of Agglomerated 10 and 40 nm Aluminum Oxyhydroxides following 4-Week Inhalation Exposure of Rats: Toxic Effects are Determined by Agglomerated, not Primary Particle Size. Toxicological Sciences 109:1, pages 152-167.
Crossref
Jürgen Pauluhn. (2009) Retrospective analysis of 4-week inhalation studies in rats with focus on fate and pulmonary toxicity of two nanosized aluminum oxyhydroxides (boehmite) and pigment-grade iron oxide (magnetite): The key metric of dose is particle mass and not particle surface area. Toxicology 259:3, pages 140-148.
Crossref
Joe L. Mauderly & Eric Garshick. 2009. Environmental Toxicants. Environmental Toxicants 551 631 .
E D Kuempel, R J Smith, D A Dankovic & L T Stayner. (2009) Rat- and human-based risk estimates of lung cancer from occupational exposure to poorly-soluble particles: A quantitative evaluation. Journal of Physics: Conference Series 151, pages 012011.
Crossref
Richard J. Kelly. (2009) Occupational medicine implications of engineered nanoscale particulate matter. Journal of Chemical Health & Safety 16:1, pages 24-39.
Crossref
Amanda S. Persad & Todd Stedeford. 2009. Information Resources in Toxicology. Information Resources in Toxicology 407 421 .
Tina M Sager, C Kommineni & Vincent Castranova. (2008) Pulmonary response to intratracheal instillation of ultrafine versus fine titanium dioxide: role of particle surface area. Particle and Fibre Toxicology 5:1.
Crossref
Ronald S. Slesinski & Duncan Turnbull. (2008) Chronic Inhalation Exposure of Rats for up to 104 Weeks to a Non–Carbon-Based Magnetite Photocopying Toner. International Journal of Toxicology 27:6, pages 427-439.
Crossref
Stephan T. Stern & Scott E. McNeil. (2008) Nanotechnology Safety Concerns Revisited. Toxicological Sciences 101:1, pages 4-21.
Crossref
David B. Warheit, Thomas R. Webb, Kenneth L. Reed, Scott Frerichs & Christie M. Sayes. (2007) Pulmonary toxicity study in rats with three forms of ultrafine-TiO2 particles: Differential responses related to surface properties. Toxicology 230:1, pages 90-104.
Crossref
Jürgen Pauluhn. (2005) Inhaled cationic amphiphilic drug-induced pulmonary phospholipidosis in rats and dogs: time-course and dose–response of biomarkers of exposure and effect. Toxicology 207:1, pages 59-72.
Crossref
Vincent Castranova. (2004) Signaling Pathways Controlling The Production Of Inflammatory Mediators in Response To Crystalline Silica Exposure: Role Of Reactive Oxygen/Nitrogen Species. Free Radical Biology and Medicine 37:7, pages 916-925.
Crossref
L.J Rausch, E.C BisingerJr.Jr. & A Sharma. (2004) Carbon black should not be classified as a human carcinogen based on rodent bioassay data. Regulatory Toxicology and Pharmacology 40:1, pages 28-41.
Crossref
Ronald F. Dodson, Mark A.L. Atkinson & Jeffrey L. Levin. (2003) Asbestos fiber length as related to potential pathogenicity: A critical review. American Journal of Industrial Medicine 44:3, pages 291-297.
Crossref
J Gallagher, R SamsIIII, J Inmon, R Gelein, A Elder, G Oberdörster & A.K Prahalad. (2003) Formation of 8-oxo-7,8-dihydro-2′-deoxyguanosine in rat lung DNA following subchronic inhalation of carbon black. Toxicology and Applied Pharmacology 190:3, pages 224-231.
Crossref
H. Muhle & I. Mangelsdorf. (2003) Inhalation toxicity of mineral particles: critical appraisal of endpoints and study design. Toxicology Letters 140-141, pages 223-228.
Crossref
Ken Donaldson, Nicholas Mills, David E. Newby, William MacNee & Vicki Stone. 2007. Nanotechnologies for the Life Sciences. Nanotechnologies for the Life Sciences.
Dale W. Porter, Lyndell Millecchia, Victor A. Robinson, Ann Hubbs, Patsy Willard, Donna Pack, Dawn Ramsey, Jeff McLaurin, Amir Khan, Douglas Landsittel, Alexander Teass & Vincent Castranova. (2002) Enhanced nitric oxide and reactive oxygen species production and damage after inhalation of silica. American Journal of Physiology-Lung Cellular and Molecular Physiology 283:2, pages L485-L493.
Crossref
Charles TimchalkHarold E Trease, Lynn L Trease, Kevin R Minard & Richard A Corley. (2016) Potential technology for studying dosimetry and response to airborne chemical and biological pollutants. Toxicology and Industrial Health 17:5-10, pages 270-276.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.