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Inhalation Toxicology
International Forum for Respiratory Research
Volume 14, 2002 - Issue 10
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Research Article

EFFECTS OF SUBCHRONIC INHALATION EXPOSURE OF RATS TO EMISSIONS FROM A DIESEL ENGINE BURNING SOYBEAN OIL-DERIVED BIODIESEL FUEL

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Pages 1017-1048 | Published online: 01 Oct 2008

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Peter Møller, Rebecca Harnung Scholten, Martin Roursgaard & Annette M. Krais. (2020) Inflammation, oxidative stress and genotoxicity responses to biodiesel emissions in cultured mammalian cells and animals. Critical Reviews in Toxicology 50:5, pages 383-401.
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Pål Magnusson, Michał Oczkowski, Johan Øvrevik, Malgorzata Gajewska, Jacek Wilczak, Jacek Biedrzycki, Katarzyna Dziendzikowska, Dariusz Kamola, Tomasz Królikowski, Marcin Kruszewski, Anna Lankoff, Remigiusz Mruk, Gunnar Brunborg, Christine Instanes, Joanna Gromadzka-Ostrowska & Oddvar Myhre. (2017) No adverse lung effects of 7- and 28-day inhalation exposure of rats to emissions from petrodiesel fuel containing 20% rapeseed methyl esters (B20) with and without particulate filter – the FuelHealth project. Inhalation Toxicology 29:5, pages 206-218.
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Annette Rohr & Jacob McDonald. (2016) Health effects of carbon-containing particulate matter: focus on sources and recent research program results. Critical Reviews in Toxicology 46:2, pages 97-137.
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Esra Mutlu, David G. Nash, Charly King, Todd Q. Krantz, William T. Preston, Ingeborg M. Kooter, Mark Higuchi, David DeMarini, William P. Linak & M. Ian Gilmour. (2015) Generation and characterization of diesel engine combustion emissions from petroleum diesel and soybean biodiesel fuels and application for inhalation exposure studies. Inhalation Toxicology 27:11, pages 515-532.
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Virginia L. Bass, Mette C. Schladweiler, Abraham Nyska, Ronald F. Thomas, Desinia B. Miller, Todd Krantz, Charly King, M. Ian Gilmour, Allen D. Ledbetter, Judy E. Richards & Urmila P. Kodavanti. (2015) Comparative cardiopulmonary toxicity of exhausts from soy-based biofuels and diesel in healthy and hypertensive rats. Inhalation Toxicology 27:11, pages 545-556.
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Stephen H. Gavett, Charles E. Wood, Marc A. Williams, Jaime M. Cyphert, Elizabeth H. Boykin, Mary J. Daniels, Lisa B. Copeland, Charly King, Todd Q. Krantz, Judy H. Richards, Debora L. Andrews, Richard H. Jaskot & M. Ian Gilmour. (2015) Soy biodiesel emissions have reduced inflammatory effects compared to diesel emissions in healthy and allergic mice. Inhalation Toxicology 27:11, pages 533-544.
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Anna A. Shvedova, Naveena Yanamala, Ashley R. Murray, Elena R. Kisin, Timur Khaliullin, Meghan K. Hatfield, Alexey V. Tkach, Q. T. Krantz, David Nash, Charly King, M. Ian Gilmour & Stephen H. Gavett. (2013) Oxidative Stress, Inflammatory Biomarkers, and Toxicity in Mouse Lung and Liver after Inhalation Exposure to 100% Biodiesel or Petroleum Diesel Emissions. Journal of Toxicology and Environmental Health, Part A 76:15, pages 907-921.
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Jürgen Bünger, Jürgen Krahl, Olaf Schröder, Lasse Schmidt & Götz A. Westphal. (2012) Potential hazards associated with combustion of bio-derived versus petroleum-derived diesel fuel. Critical Reviews in Toxicology 42:9, pages 732-750.
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Thomas W. Hesterberg, Christopher M. Long, William B. Bunn, Sonja N. Sax, Charles A. Lapin & Peter A. Valberg. (2009) Non-cancer health effects of diesel exhaust: A critical assessment of recent human and animal toxicological literature. Critical Reviews in Toxicology 39:3, pages 195-227.
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Robert L. McCormick. (2007) The Impact of Biodiesel on Pollutant Emissions and Public Health. Inhalation Toxicology 19:12, pages 1033-1039.
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M. D. Reed, L. F. Blair, K. Burling, I. Daly, A. P. Gigliotti, R. Gudi, M. D. Mercieca, J. D. McDonald, D. J. Naas, J. P. O'Callaghan, S. K. Seilkop, N. L. Ronsko, V. O. Wagner & R. C. Kraska. (2005) Health Effects of Subchronic Exposure to Diesel–Water Emulsion Emission. Inhalation Toxicology 17:14, pages 851-870.
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JeanClare Seagrave, Jacob D. McDonald, Matthew D. Reed, Steven K. Seilkop & Joe L. Mauderly. (2005) Responses to Subchronic Inhalation of Low Concentrations of Diesel Exhaust and Hardwood Smoke Measured in Rat Bronchoalveolar Lavage Fluid. Inhalation Toxicology 17:12, pages 657-670.
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Naveena Yanamala, Meghan K. Hatfield, Mariana T. Farcas, Diane Schwegler-Berry, Jon A. Hummer, Michael R. Shurin, M. Eileen Birch, Dmitriy W. Gutkin, Elena Kisin, Valerian E. Kagan, Aleksandar D. Bugarski & Anna A. Shvedova. (2013) Biodiesel versus diesel exposure: Enhanced pulmonary inflammation, oxidative stress, and differential morphological changes in the mouse lung. Toxicology and Applied Pharmacology 272:2, pages 373-383.
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Nora Traviss, Brett Amy Thelen, Jaime Kathryn Ingalls & Melinda Dawn Treadwell. (2011) Evaluation of biodiesel’s impact on real-world occupational and environmental particulate matter exposures at a municipal facility in Keene, NH. Air Quality, Atmosphere & Health 5:1, pages 101-114.
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Kerstin Bluhm, Sebastian Heger, Thomas-Benjamin Seiler, Arnold V. Hallare, Andreas Schäffer & Henner Hollert. (2012) Toxicological and ecotoxicological potencies of biofuels used for the transport sector—a literature review. Energy & Environmental Science 5:6, pages 7381.
Crossref
Prashant Kumar, Alan Robins, Sotiris Vardoulakis & Paul Quincey. (2011) Technical challenges in tackling regulatory concerns for urban atmospheric nanoparticles. Particuology 9:6, pages 566-571.
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Avinash Kumar Agarwal, Tarun Gupta & Abhishek Kothari. (2011) Particulate emissions from biodiesel vs diesel fuelled compression ignition engine. Renewable and Sustainable Energy Reviews 15:6, pages 3278-3300.
Crossref
Andrew D. Kraft & G. Jean Harry. (2011) Features of Microglia and Neuroinflammation Relevant to Environmental Exposure and Neurotoxicity. International Journal of Environmental Research and Public Health 8:7, pages 2980-3018.
Crossref
Jeremy P. Langrish, Mark W. Frampton & Anders Blomberg. 2011. Cardiovascular Effects of Inhaled Ultrafine and Nanosized Particles. Cardiovascular Effects of Inhaled Ultrafine and Nanosized Particles 217 239 .
Melinda E. Lull & Michelle L. Block. (2010) Microglial activation and chronic neurodegeneration. Neurotherapeutics 7:4, pages 354-365.
Crossref
Prashant Kumar, Alan Robins & Helen ApSimon. (2010) Nanoparticle emissions from biofuelled vehicles-their characteristics and impact on the number-based regulation of atmospheric particles. Atmospheric Science Letters 11:4, pages 327-331.
Crossref
Jôse Mára Brito, Luciano Belotti, Alessandra C. Toledo, Leila Antonangelo, Flávio S. Silva, Débora S. Alvim, Paulo A. Andre, Paulo H. N. Saldiva & Dolores H. R. F. Rivero. (2010) Acute Cardiovascular and Inflammatory Toxicity Induced by Inhalation of Diesel and Biodiesel Exhaust Particles. Toxicological Sciences 116:1, pages 67-78.
Crossref
Duncan G. Fullerton, Khuzwayo Jere, Kondwani Jambo, Neeta S. Kulkarni, Eduard E. Zijlstra, Jonathan Grigg, Neil French, Malcolm E. Molyneux & Stephen B. Gordon. (2009) Domestic smoke exposure is associated with alveolar macrophage particulate load. Tropical Medicine & International Health 14:3, pages 349-354.
Crossref
Joe L. Mauderly & Eric Garshick. 2009. Environmental Toxicants. Environmental Toxicants 551 631 .
R. Poon, I. Chu, V.E. Valli, L. Graham, A. Yagminas, B. Hollebone, G. Rideout & M. Fingas. (2007) Effects of three biodiesels and a low sulfur diesel in male rats – A pilot 4-week oral study. Food and Chemical Toxicology 45:10, pages 1830-1837.
Crossref
I. Annesi-Maesano. (2007) Il y a une relation de type dose-réponse inversée entre le carbone présent dans les macrophages des voies aériennes et la fonction pulmonaire chez l’enfant. Revue des Maladies Respiratoires 24, pages 22-23.
Crossref
Kimberly J. Swanson, Michael C. Madden & Andrew J. Ghio. (2007) Biodiesel Exhaust: The Need for Health Effects Research. Environmental Health Perspectives 115:4, pages 496-499.
Crossref
Heejung Jung, David B. Kittelson & Michael R. Zachariah. (2006) Characteristics of SME Biodiesel-Fueled Diesel Particle Emissions and the Kinetics of Oxidation. Environmental Science & Technology 40:16, pages 4949-4955.
Crossref
Neeta Kulkarni, Nevil Pierse, Lesley Rushton & Jonathan Grigg. (2006) Carbon in Airway Macrophages and Lung Function in Children. New England Journal of Medicine 355:1, pages 21-30.
Crossref
MD ReedLF Blair, K Burling, I Daly, AP Gigliotti, R Gudi, MD Mercieca, JD McDonald, JP O’Callaghan, SK Seilkop, NL Ronsko, VO Wagner & RC Kraska. (2016) Health effects of subchronic exposure to diesel-water-methanol emulsion emission. Toxicology and Industrial Health 22:2, pages 65-85.
Crossref
Michelle L. Block & Jau-Shyong Hong. (2005) Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism. Progress in Neurobiology 76:2, pages 77-98.
Crossref
. 2005. The Biodiesel Handbook. The Biodiesel Handbook.
A. Campbell, M. Oldham, A. Becaria, S.C. Bondy, D. Meacher, C. Sioutas, C. Misra, L.B. Mendez & M. Kleinman. (2005) Particulate Matter in Polluted Air May Increase Biomarkers of Inflammation in Mouse Brain. NeuroToxicology 26:1, pages 133-140.
Crossref
M. L. Block, X. Wu, Z. Pei, G. Li, T. Wang, L. Qin, B. Wilson, J. Yang, J. S. Hong & B. Veronesi. (2004) Nanometer size diesel exhaust particles are selectively toxic to dopaminergic neurons: the role of microglia, phagocytosis, and NADPH oxidase. The FASEB Journal 18:13, pages 1618-1620.
Crossref

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