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Inhalation Toxicology
International Forum for Respiratory Research
Volume 14, 2002 - Issue 11
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Research Article

TOXICOLOGIC EVALUATION OF HUMECTANTS ADDED TO CIGARETTE TOBACCO: 13-WEEK SMOKE INHALATION STUDY OF GLYCERIN AND PROPYLENE GLYCOL IN FISCHER 344 RATS

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Pages 1135-1152 | Published online: 01 Oct 2008

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Hitoshi Fujimoto, Hiroyuki Tsuji, Chigusa Okubo, Ichiro Fukuda, Tomoki Nishino, K. Monica Lee, Roger Renne & Hiroyuki Yoshimura. (2015) Biological responses in rats exposed to mainstream smoke from a heated cigarette compared to a conventional reference cigarette. Inhalation Toxicology 27:4, pages 224-236.
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Charles L. Gaworski, Karl A. Wagner, Michael J. Morton & Michael J. Oldham. (2011) Insights from a multi-year program designed to test the impact of ingredients on mainstream cigarette smoke toxicity. Inhalation Toxicology 23:sup1, pages 172-183.
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Charles L. Gaworski, Michael J. Oldham, Karl A. Wagner, Christopher R.E. Coggins & George J. Patskan. (2011) An evaluation of the toxicity of 95 ingredients added individually to experimental cigarettes: approach and methods. Inhalation Toxicology 23:sup1, pages 1-12.
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Ranulfo Lemus, Edward L. Carmines, Erik Van Miert, Christopher R. E. Coggins, Erwin Anskeit, Birgit Gerstenberg, Thomas J. Meisgen, Heike Schramke, Regina Stabbert, Hartmut Völkel & Piter M. Terpstra. (2007) Toxicological Comparisons of Cigarettes Containing Different Amounts of Vanillin. Inhalation Toxicology 19:8, pages 683-699.
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J. T. Hamm, S. Yee, N. Rajendran, R. L. Morrissey, S. J. Richter & M. Misra. (2007) Histological Alterations in Male A/J Mice Following Nose-Only Exposure to Tobacco Smoke. Inhalation Toxicology 19:5, pages 405-418.
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Yan Xizheng, Liza Valentín-Blasini, Clifford Watson & Roberto Bravo Cardenas. (2018) Determination of Humectants in Tobacco Filler by High Performance Chromatography/Single Quadrupole Mass Spectrometry. Beiträge zur Tabakforschung International/Contributions to Tobacco Research 28:4, pages 170-178.
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E. Roemer, R. Dempsey, J. Hirter, A. Deger Evans, S. Weber, A. Ode, S. Wittke & M.K. Schorp. (2014) Toxicological assessment of kretek cigarettes Part 6: The impact of ingredients added to kretek cigarettes on smoke chemistry and in vitro toxicity. Regulatory Toxicology and Pharmacology 70, pages S66-S80.
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H Klus, G Scherer & L Müller. (2012) Influence of Additives on Cigarette Related Health Risks. Beiträge zur Tabakforschung International/Contributions to Tobacco Research 25:3, pages 412-493.
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Charleata A. Carter & Manoj Misra. (2010) Effects of Short-Term Cigarette Smoke Exposure on Fischer 344 Rats and on Selected Lung Proteins. Toxicologic Pathology 38:3, pages 402-415.
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Charles L. Gaworski, Michael J. Oldham & Christopher R.E. Coggins. (2010) Toxicological considerations on the use of propylene glycol as a humectant in cigarettes. Toxicology 269:1, pages 54-66.
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Joanne L. Wright, Manuel Cosio & Andrew Churg. (2008) Animal models of chronic obstructive pulmonary disease. American Journal of Physiology-Lung Cellular and Molecular Physiology 295:1, pages L1-L15.
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Careen Merckel, Fritz Pragst, Astrid Ratzinger, Beat Aebi, Werner Bernhard & Frank Sporkert. (2006) Application of headspace solid phase microextraction to qualitative and quantitative analysis of tobacco additives in cigarettes. Journal of Chromatography A 1116:1-2, pages 10-19.
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E.L. Carmines & C.L. Gaworski. (2005) Toxicological evaluation of glycerin as a cigarette ingredient. Food and Chemical Toxicology 43:10, pages 1521-1539.
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E.L. Carmines, R. Lemus & C.L. Gaworski. (2005) Toxicologic evaluation of licorice extract as a cigarette ingredient. Food and Chemical Toxicology 43:9, pages 1303-1322.
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