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Inhalation Toxicology
International Forum for Respiratory Research
Volume 15, 2003 - Issue 14
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Research Article

Pulmonary Effects and Clearance After Long-Term Inhalation of Potassium Octatitanate Whiskers in Rats

Hiroshi Yamato Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, JapanCorrespondence[email protected]
,
Takako Oyabu Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan
,
Akira Ogami Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan
,
Yasuo Morimoto Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan
,
Toshiaki Higashi Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan
,
Isamu Tanaka Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan
,
Sumiyo Ishimatsu School of Health Sciences, University of Occupational and Environmental Health, Japan
,
Hajime Hori School of Health Sciences, University of Occupational and Environmental Health, Japan
&
Takahiko Kasai Department of Pathology, Kurobe City Hospital, Kurobe City, Japan
 show all
Pages 1421-1434 | Published online: 01 Oct 2008

Citations (12)

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Read on this site (3)

Sumiyo Ishimatsu, Hajime Hori, Takahiko Kasai, Akira Ogami, Yasuo Morimoto, Takako Oyabu & Isamu Tanaka. (2009) Biological effect of carbon graphite whisker in rat lung by long-term Inhalation. Inhalation Toxicology 21:8, pages 668-673.
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Akira Ogami, Yasuo Morimoto, Toshihiko Myojo, Takako Oyabu, Masahiro Murakami, Kenichiro Nishi, Chikara Kadoya & Isamu Tanaka. (2007) Histopathological Changes in Rat Lung Following Intratracheal Instillation of Silicon Carbide Whiskers and Potassium Octatitanate Whiskers. Inhalation Toxicology 19:9, pages 753-758.
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Izumi Akiyama, Akira Ogami, Takako Oyabu, Hiroshi Yamato, Yasuo Morimoto & Isamu Tanaka. (2007) Pulmonary Effects and Biopersistence of Deposited Silicon Carbide Whisker After 1-Year Inhalation in Rats. Inhalation Toxicology 19:2, pages 141-147.
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Articles from other publishers (9)

Mohamed Abdelgied, Ahmed M. El-Gazzar, William T. Alexander, Takamasa Numano, Masaaki Iigou, Aya Naiki-Ito, Hiroshi Takase, Akihiko Hirose, Yuhji Taquahashi, Jun Kanno, Mona Abdelhamid, Khaled Abbas Abdou, Satoru Takahashi, David B. Alexander & Hiroyuki Tsuda. (2019) Carcinogenic effect of potassium octatitanate (POT) fibers in the lung and pleura of male Fischer 344 rats after intrapulmonary administration. Particle and Fibre Toxicology 16:1.
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Mohamed Abdelgied, Ahmed M. El-Gazzar, David B. Alexander, William T. Alexander, Takamasa Numano, Masaaki Iigou, Aya Naiki-Ito, Hiroshi Takase, Khaled Abbas Abdou, Akihiko Hirose, Yuhji Taquahashi, Jun Kanno, Mona Abdelhamid, Hiroyuki Tsuda & Satoru Takahashi. (2019) Pulmonary and pleural toxicity of potassium octatitanate fibers, rutile titanium dioxide nanoparticles, and MWCNT-7 in male Fischer 344 rats. Archives of Toxicology 93:4, pages 909-920.
Crossref
Mohamed Abdelgied, Ahmed M. El-Gazzar, David B. Alexander, William T. Alexander, Takamasa Numano, Masaaki Iigou, Aya Naiki-Ito, Hirotsugu Takase, Khaled Abbas Abdou, Akihiko Hirose, Yuhji Taquahashi, Jun Kanno, Hiroyuki Tsuda & Satoru Takahashi. (2018) Potassium octatitanate fibers induce persistent lung and pleural injury and are possibly carcinogenic in male Fischer 344 rats. Cancer Science 109:7, pages 2164-2177.
Crossref
Gail Drummond, Ruth Bevan & Paul Harrison. (2016) A comparison of the results from intra-pleural and intra-peritoneal studies with those from inhalation and intratracheal tests for the assessment of pulmonary responses to inhalable dusts and fibres. Regulatory Toxicology and Pharmacology 81, pages 89-105.
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Yasuko Obata, Yasuo Morimoto, Masami Hirohashi, Akira Ogami, Takako Oyabu, Toshihiko Myojo, Shoko Kawanami, Seichi Horie, Hiroko Nagatomo, Masahiro Murakami & Isamu Tanaka. (2011) Expression of Heme Oxygenase‐1 in the Lungs of Rats Exposed to Potassium Octatitanate Whiskers. Journal of Occupational Health 53:4, pages 267-273.
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Takako Oyabu, Akira Ogami, Yasuo Morimoto, Toshihiko Myojo, Masahiro Murakami, Hiroshi Yamato & Isamu Tanaka. (2008) Simple Flow‐through Solubility Measurement Apparatus and its Effectiveness for Hazard Assessment of Particles/Fibers. Journal of Occupational Health 50:3, pages 279-282.
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Takako Oyabu, Hiroshi Yamato, Akira Ogami, Yasuo Morimoto, Izumi AkiyamaSumiyo Ishimatsu, Hajime Hori & Isamu Tanaka. (2006) The Effect of Lung Burden on Biopersistence and Pulmonary Effects in Rats Exposed to Potassium Octatitanate Whiskers by Intratracheal Instillation. Journal of Occupational Health 48:1, pages 44-48.
Crossref
Takako Oyabu, Hiroshi Yamato, Akira Ogami, Yasuo Morimoto, Izumi AkiyamaSumiyo Ishimatsu, Hajime Hori & Isamu Tanaka. (2004) The Effect of Lung Burden on Biopersistence and Pulmonary Effects in Rats Exposed to Potassium Octatitanate Whiskers by Inhalation. Journal of Occupational Health 46:5, pages 382-390.
Crossref
Helmut A Greim. (2004) Research needs to improve risk assessment of fiber toxicity. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 553:1-2, pages 11-22.
Crossref

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