Publication Cover
Inhalation Toxicology
International Forum for Respiratory Research
Volume 19, 2007 - Issue 13
399
Views
57
CrossRef citations to date
0
Altmetric
Research Article

The Cellular and Genomic Response of an Immortalized Microglia Cell Line (BV2) to Concentrated Ambient Particulate Matter

, , , , , & show all
Pages 1079-1087 | Received 02 May 2007, Accepted 14 Jul 2007, Published online: 06 Oct 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Yuh-Chin T. Huang. (2013) The Role of in Vitro Gene Expression Profiling in Particulate Matter Health Research. Journal of Toxicology and Environmental Health, Part B 16:6, pages 381-394.
Read now
Lung-Chi Chen, Jing-Shiang Hwang, Ramona Lall, George Thurston & Morton Lippmann. (2010) Alteration of cardiac function in ApoE−/− mice by subchronic urban and regional inhalation exposure to concentrated ambient PM2.5. Inhalation Toxicology 22:7, pages 580-592.
Read now
Morton Lippmann & Lung-Chi Chen. (2009) Health effects of concentrated ambient air particulate matter (CAPs) and its components. Critical Reviews in Toxicology 39:10, pages 865-913.
Read now

Articles from other publishers (53)

Sahar H. Pradhan, Matthew Gibb, Alec T. Kramer & Christie M. Sayes. (2023) Peripheral (lung-to-brain) exposure to diesel particulate matter induces oxidative stress and increased markers for systemic inflammation. Environmental Research 231, pages 116267.
Crossref
Hongsheng Xie, Yuan Cao, Jiafeng Li, Yichen Lyu, Neil Roberts & Zhiyun Jia. (2023) Affective disorder and brain alterations in children and adolescents exposed to outdoor air pollution. Journal of Affective Disorders 331, pages 413-424.
Crossref
Melania Maria Serafini, Ambra Maddalon, Martina Iulini & Valentina Galbiati. (2022) Air Pollution: Possible Interaction between the Immune and Nervous System?. International Journal of Environmental Research and Public Health 19:23, pages 16037.
Crossref
Haneen Khreis, Christiaan Bredell, Kwan Wai Fung, Lucy Hong, Magdalena Szybka, Veronica Phillips, Ali Abbas, Youn-Hee Lim, Zorana Jovanovic Andersen, James Woodcock & Carol Brayne. (2022) Impact of Long-Term Air Pollution Exposure on Incidence of Neurodegenerative Diseases: A Protocol for A Systematic Review and Exposure-Response Meta-Analysis. Environment International, pages 107596.
Crossref
Jie Song, Keyang Han, Ya Wang, Rongrong Qu, Yuan Liu, Shaolan Wang, Yinbiao Wang, Zhen An, Juan Li, Hui Wu & Weidong Wu. (2022) Microglial Activation and Oxidative Stress in PM2.5-Induced Neurodegenerative Disorders. Antioxidants 11:8, pages 1482.
Crossref
Dabin Choi, Gaheon Lee, Kyung Hwa Kim & Hyunsu Bae. (2022) Particulate Matter Exacerbates the Death of Dopaminergic Neurons in Parkinson’s Disease through an Inflammatory Response. International Journal of Molecular Sciences 23:12, pages 6487.
Crossref
Shen Song, Rongli Qiu, Xiaodan Jin, Zhuxiu Zhou, Jin Yan, Qiaochan Ou, Xiao Liu, Weidong Li, Yiqing Mao, Weifeng Yao & Tulin Lu. (2022) Mechanism exploration of ancient pharmaceutic processing (Paozhi) improving the gastroprotective efficacy of Aucklandiae Radix. Journal of Ethnopharmacology 287, pages 114911.
Crossref
Yan Deng, Hang Zhao, Ying Liu, Huo Liu, Jingang Shi, Chenkai Zhao & Miao He. (2022) Association of using biomass fuel for cooking with depression and anxiety symptoms in older Chinese adults. Science of The Total Environment 811, pages 152256.
Crossref
Chatsuda Mata, Sattamat Lappharat, Yaowares Chusiri, Metida Khumjorhor & Nutta Taneepanichskul. (2022) Effect of residential proximity to the lignite-fired power plant on depression, sleep quality, and morning salivary cortisol in the elderly. Science of The Total Environment 811, pages 151346.
Crossref
You Jung Kang, Hsih‐Yin Tan, Charles Y. Lee & Hansang Cho. (2021) An Air Particulate Pollutant Induces Neuroinflammation and Neurodegeneration in Human Brain Models. Advanced Science 8:21, pages 2101251.
Crossref
Mojtaba Ehsanifar, Banihashemian SS & Masoud Ehsanifar. (2021) Exposure to Air Pollution Nanoparticles: Oxidative Stress and Neuroinflammation. Journal of Biomedical Research & Environmental Sciences 2:10, pages 964-976.
Crossref
Rebecca H. Morris, Serena J. Counsell, Imelda M. McGonnell & Claire Thornton. (2021) Early life exposure to air pollution impacts neuronal and glial cell function leading to impaired neurodevelopment. BioEssays 43:9, pages 2000288.
Crossref
Chengyue Zhu, Kannan Maharajan, Kechun Liu & Yun Zhang. (2021) Role of atmospheric particulate matter exposure in COVID-19 and other health risks in human: A review. Environmental Research 198, pages 111281.
Crossref
Shu-Xin Tian, Wen Cheng, Jing-Jing Lu, Fang-Mei Zhou, Zhi-Shan Ding & Bing-Qi Zhu. (2021) Role of Militarine in PM2.5-Induced BV-2 Cell Damage. Neurochemical Research 46:6, pages 1423-1434.
Crossref
Tauqeer Hussain Mallhi, Muhammad Hammad Butt, Abrar Ahmad, Shahzadi Misbah, Suleman Atique & Yusra Habib Khan. 2021. Environmental Contaminants and Neurological Disorders. Environmental Contaminants and Neurological Disorders 31 47 .
Huda Asif & Mehdi Mirsaeidi. 2021. Climate Change and Global Public Health. Climate Change and Global Public Health 459 482 .
Michael Sigfrid S. Reyes & Paul Mark B. Medina. (2020) Environmental pollutant exposure can exacerbate COVID-19 neurologic symptoms. Medical Hypotheses 144, pages 110136.
Crossref
Jian-Quan Shi, Bian-Rong Wang, Teng Jiang, Li Gao, Ying-Dong Zhang & Jun Xu. (2020) NLRP3 Inflammasome: A Potential Therapeutic Target in Fine Particulate Matter-Induced Neuroinflammation in Alzheimer’s Disease. Journal of Alzheimer's Disease 77:3, pages 923-934.
Crossref
Xiaozheng Zhu, Xintong Ji, Yikai Shou, Yilu Huang, Yu Hu & Huanhuan Wang. (2020) Recent advances in understanding the mechanisms of PM2.5-mediated neurodegenerative diseases. Toxicology Letters 329, pages 31-37.
Crossref
Mireia Gómez-Budia, Henna Konttinen, Liudmila Saveleva, Paula Korhonen, Pasi I. Jalava, Katja M. Kanninen & Tarja Malm. (2020) Glial smog: Interplay between air pollution and astrocyte-microglia interactions. Neurochemistry International 136, pages 104715.
Crossref
Arthur K. Cho, Yasuhiro Shinkai, Debra A. Schmitz, Emma Di Stefano, Arantza Eiguren-Fernandez, Aline Lefol Nani Guarieiro, Erika M. Salinas, John R. Froines & William P. Melega. (2020) Chemical and Biological Characterization of Particulate Matter (PM 2.5) and Volatile Organic Compounds Collected at Different Sites in the Los Angeles Basin. Applied Sciences 10:9, pages 3245.
Crossref
Sweelin Chew, Natalia Kolosowska, Liudmila Saveleva, Tarja Malm & Katja M. Kanninen. (2020) Impairment of mitochondrial function by particulate matter: Implications for the brain. Neurochemistry International 135, pages 104694.
Crossref
Morton Lippmann. 2020. Environmental Toxicants. Environmental Toxicants 285 365 .
Shu-Jun Fan, Joachim Heinrich, Michael S. Bloom, Tian-Yu Zhao, Tong-Xing Shi, Wen-Ru Feng, Yi Sun, Ji-Chuan Shen, Zhi-Cong Yang, Bo-Yi Yang & Guang-Hui Dong. (2020) Ambient air pollution and depression: A systematic review with meta-analysis up to 2019. Science of The Total Environment 701, pages 134721.
Crossref
Jing-Li Yue, Hui Liu, Hui Li, Jia-Jia Liu, Yong-Hua Hu, Jing Wang, Lin Lu & Feng Wang. (2020) Association between ambient particulate matter and hospitalization for anxiety in China: A multicity case-crossover study. International Journal of Hygiene and Environmental Health 223:1, pages 171-178.
Crossref
Caterina Scuderi & Alexei Verkhratsky. 2020. Autism. Autism 301 330 .
Yu-Yao Zu, Quan-Fang Liu, Shu-Xin Tian, Li-Xia Jin, Fu-Sheng Jiang, Mei-Ya Li, Bing-Qi Zhu & Zhi-Shan Ding. (2019) Effective fraction of Bletilla striata reduces the inflammatory cytokine production induced by water and organic extracts of airborne fine particulate matter (PM2.5) in vitro. BMC Complementary and Alternative Medicine 19:1.
Crossref
Yikai Shou, Yilu Huang, Xiaozheng Zhu, Cuiqing Liu, Yu Hu & Huanhuan Wang. (2019) A review of the possible associations between ambient PM2.5 exposures and the development of Alzheimer's disease. Ecotoxicology and Environmental Safety 174, pages 344-352.
Crossref
Jason Kilian & Masashi Kitazawa. (2018) The emerging risk of exposure to air pollution on cognitive decline and Alzheimer's disease – Evidence from epidemiological and animal studies. Biomedical Journal 41:3, pages 141-162.
Crossref
Tse Joyce KY. (2017) Nitrogen Oxides Induced Neurodegeneration as Examined by Nuclear Magnetic Resonance. Journal of Neurology & Stroke 7:5.
Crossref
Richard L. Jayaraj, Eric A. Rodriguez, Yi Wang & Michelle L. Block. (2017) Outdoor Ambient Air Pollution and Neurodegenerative Diseases: the Neuroinflammation Hypothesis. Current Environmental Health Reports 4:2, pages 166-179.
Crossref
Vivian C. Pun, Justin Manjourides & Helen Suh. (2017) Association of Ambient Air Pollution with Depressive and Anxiety Symptoms in Older Adults: Results from the NSHAP Study. Environmental Health Perspectives 125:3, pages 342-348.
Crossref
Min-Xuan Xu, Yan-Fang Zhu, Hsiao-Feng Chang & Ying Liang. (2016) Nanoceria restrains PM2.5-induced metabolic disorder and hypothalamus inflammation by inhibition of astrocytes activation related NF-κB pathway in Nrf2 deficient mice. Free Radical Biology and Medicine 99, pages 259-272.
Crossref
Ting Li, Jianya Zhao, Jianbin Ge, Jianbin Yang, Xinjian Song, Cheng Wang, Jiamin Mao, Yan Zhang, Ye Zou, Yanmei Liu & Gang Chen. (2016) Particulate Matter Facilitates C6 Glioma Cells Activation and the Release of Inflammatory Factors Through MAPK and JAK2/STAT3 Pathways. Neurochemical Research 41:8, pages 1969-1981.
Crossref
Christen L. Mumaw, Shannon Levesque, Constance McGraw, Sarah Robertson, Selita Lucas, Jillian E Stafflinger, Matthew J. Campen, Pamela Hall, Jeffrey P. Norenberg, Tamara Anderson, Amie K. Lund, Jacob D. McDonald, Andrew K. Ottens & Michelle L. Block. (2016) Microglial priming through the lung—brain axis: the role of air pollution‐induced circulating factors. The FASEB Journal 30:5, pages 1880-1891.
Crossref
Jonathan M. Borkum. (2016) Migraine Triggers and Oxidative Stress: A Narrative Review and Synthesis. Headache: The Journal of Head and Face Pain 56:1, pages 12-35.
Crossref
Ying Liu, Yan-Yan Chen, Ji-Yu Cao, Fang-Biao Tao, Xiao-Xia Zhu, Ci-Jiang Yao, Dao-Jun Chen, Zhen Che, Qi-Hong Zhao & Long-Ping Wen. (2015) Oxidative stress, apoptosis, and cell cycle arrest are induced in primary fetal alveolar type II epithelial cells exposed to fine particulate matter from cooking oil fumes. Environmental Science and Pollution Research 22:13, pages 9728-9741.
Crossref
Gaoyi Yao, Huifeng Yue, Yang Yun & Nan Sang. (2015) Chronic SO2 inhalation above environmental standard impairs neuronal behavior and represses glutamate receptor gene expression and memory-related kinase activation via neuroinflammation in rats. Environmental Research 137, pages 85-93.
Crossref
Brian Chorley, William Ward, Steven O. Simmons, Beena Vallanat & Bellina Veronesi. (2014) The cellular and genomic response of rat dopaminergic neurons (N27) to coated nanosilver. NeuroToxicology 45, pages 12-21.
Crossref
Arezoo Campbell, Nancy Daher, Parrisa Solaimani, Kriscelle Mendoza & Constantinos Sioutas. (2014) Human brain derived cells respond in a type-specific manner after exposure to urban particulate matter (PM). Toxicology in Vitro 28:7, pages 1290-1295.
Crossref
Fares Zeidán-Chuliá, Alla B. Salmina, Natalia A. Malinovskaya, Mami Noda, Alexei Verkhratsky & José Cláudio Fonseca Moreira. (2014) The glial perspective of autism spectrum disorders. Neuroscience & Biobehavioral Reviews 38, pages 160-172.
Crossref
Patricia Gillespie, Julianne Tajuba, Morton Lippmann, Lung-Chi Chen & Bellina Veronesi. (2013) Particulate matter neurotoxicity in culture is size-dependent. NeuroToxicology 36, pages 112-117.
Crossref
Sebastian Oeder, Rudolf A. Jörres, Ingrid Weichenmeier, Gudrun Pusch, Wolfgang Schober, Florian Pfab, Heidrun Behrendt, Rudolf Schierl, Angelika Kronseder, Dennis Nowak, Silvio Dietrich, Enrique Fernández-Caldas, Jutta Lintelmann, Ralf Zimmermann, Roland Lang, Jörg Mages, Hermann Fromme & Jeroen T. M. Buters. (2012) Airborne Indoor Particles from Schools Are More Toxic than Outdoor Particles. American Journal of Respiratory Cell and Molecular Biology 47:5, pages 575-582.
Crossref
Michelle L. Block, Alison Elder, Richard L. Auten, Staci D. Bilbo, Honglei Chen, Jiu-Chiuan Chen, Deborah A. Cory-Slechta, Daniel Costa, David Diaz-Sanchez, David C. Dorman, Diane R. Gold, Kimberly Gray, Hueiwang Anna Jeng, Joel D. Kaufman, Michael T. Kleinman, Annette Kirshner, Cindy Lawler, David S. Miller, Srikanth S. Nadadur, Beate Ritz, Erin O. Semmens, Leonardo H. Tonelli, Bellina Veronesi, Robert O. Wright & Rosalind J. Wright. (2012) The outdoor air pollution and brain health workshop. NeuroToxicology 33:5, pages 972-984.
Crossref
R.G. Lucchini, D.C. Dorman, A. Elder & B. Veronesi. (2012) Neurological impacts from inhalation of pollutants and the nose–brain connection. NeuroToxicology 33:4, pages 838-841.
Crossref
Morton Lippmann. (2011) Particulate matter (PM) air pollution and health: regulatory and policy implications. Air Quality, Atmosphere & Health 5:2, pages 237-241.
Crossref
Sermin Genc, Zeynep Zadeoglulari, Stefan H. Fuss & Kursad Genc. (2012) The Adverse Effects of Air Pollution on the Nervous System. Journal of Toxicology 2012, pages 1-23.
Crossref
Damiën van Berlo, Maja Hullmann & Roel P. F. Schins. 2012. Molecular, Clinical and Environmental Toxicology. Molecular, Clinical and Environmental Toxicology 165 217 .
L K Fonken, X Xu, Z M Weil, G Chen, Q Sun, S Rajagopalan & R J Nelson. (2011) Air pollution impairs cognition, provokes depressive-like behaviors and alters hippocampal cytokine expression and morphology. Molecular Psychiatry 16:10, pages 987-995.
Crossref
Andrew D. Kraft & G. Jean Harry. (2011) Features of Microglia and Neuroinflammation Relevant to Environmental Exposure and Neurotoxicity. International Journal of Environmental Research and Public Health 8:7, pages 2980-3018.
Crossref
Michelle L. Block & Lilian Calderón-Garcidueñas. (2009) Air pollution: mechanisms of neuroinflammation and CNS disease. Trends in Neurosciences 32:9, pages 506-516.
Crossref
Tanapon Phenrat, Thomas C. Long, Gregory V. Lowry & Bellina Veronesi. (2008) Partial Oxidation (“Aging”) and Surface Modification Decrease the Toxicity of Nanosized Zerovalent Iron. Environmental Science & Technology 43:1, pages 195-200.
Crossref
Sheba M.J. MohanKumar, Arezoo Campbell, Michelle Block & Bellina Veronesi. (2008) Particulate matter, oxidative stress and neurotoxicity. NeuroToxicology 29:3, pages 479-488.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.