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Inhalation Toxicology
International Forum for Respiratory Research
Volume 29, 2017 - Issue 2
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Research Article

Molecular mechanisms of pulmonary response progression in crystalline silica exposed rats

Rajendran SellamuthuHealth Effects Laboratory Division, National Institute for Occupational Safety and Health (NIOSH), Morgantown, WV, USA
,
Christina UmbrightHealth Effects Laboratory Division, National Institute for Occupational Safety and Health (NIOSH), Morgantown, WV, USA
,
Jenny R. RobertsHealth Effects Laboratory Division, National Institute for Occupational Safety and Health (NIOSH), Morgantown, WV, USA
,
Shih-Houng YoungHealth Effects Laboratory Division, National Institute for Occupational Safety and Health (NIOSH), Morgantown, WV, USA
,
Diana RichardsonHealth Effects Laboratory Division, National Institute for Occupational Safety and Health (NIOSH), Morgantown, WV, USA
,
Walter McKinneyHealth Effects Laboratory Division, National Institute for Occupational Safety and Health (NIOSH), Morgantown, WV, USA
,
Bean T. ChenHealth Effects Laboratory Division, National Institute for Occupational Safety and Health (NIOSH), Morgantown, WV, USA
,
Shengqiao LiHealth Effects Laboratory Division, National Institute for Occupational Safety and Health (NIOSH), Morgantown, WV, USA
,
Michael KashonHealth Effects Laboratory Division, National Institute for Occupational Safety and Health (NIOSH), Morgantown, WV, USA
&
Pius JosephHealth Effects Laboratory Division, National Institute for Occupational Safety and Health (NIOSH), Morgantown, WV, USACorrespondence[email protected]
 show all
Pages 53-64 | Received 10 Nov 2016, Accepted 09 Jan 2017, Published online: 19 Mar 2017

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Ye Zhang, Michael Story, Samrawit Yeshitla, Xiaoyu Wang, Robert R. Scully, Corey Theriot, Honglu Wu, Valerie E. Ryder & Chiu-wing Lam. (2023) Persistent changes in expression of genes involved in inflammation and fibrosis in the lungs of rats exposed to airborne lunar dust. Inhalation Toxicology 35:5-6, pages 139-156.
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Jessica Begay, Bethany Sanchez, Abigail Wheeler, Floyd Baldwin$suffix/text()$suffix/text(), Selita Lucas, Guy Herbert, Yoselin Ordonez Suarez, Chris Shuey, Zachary Klaver, Jack R. Harkema, James G. Wagner, Masako Morishita, Barry Bleske, Katherine E. Zychowski & Matthew J. Campen. (2021) Assessment of particulate matter toxicity and physicochemistry at the Claim 28 uranium mine site in Blue Gap, AZ. Journal of Toxicology and Environmental Health, Part A 84:1, pages 31-48.
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Kevin Dillon, Karin Jochims, Ursula Gerigk, Franz Jost, Hans Kobesen & Ruth Bialucha. (2020) No pathogenic responses in rat lung upon exposure to ground granulated blast furnace slag (GGBS). Inhalation Toxicology 32:1, pages 39-52.
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Hajime Kawasaki. (2019) A review of the fate of inhaled α-quartz in the lungs of rats. Inhalation Toxicology 31:1, pages 25-34.
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Christina Umbright, Rajendran Sellamuthu, Jenny R. Roberts, Shih-Houng Young, Diana Richardson, Diane Schwegler-Berry, Walter McKinney, Bean Chen, Ja Kook Gu, Michael Kashon & Pius Joseph. (2017) Pulmonary toxicity and global gene expression changes in response to sub-chronic inhalation exposure to crystalline silica in rats. Journal of Toxicology and Environmental Health, Part A 80:23-24, pages 1349-1368.
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Articles from other publishers (11)

Pius Joseph. 2022. Genomic and Epigenomic Biomarkers of Toxicology and Disease. Genomic and Epigenomic Biomarkers of Toxicology and Disease 133 161 .
Ahmed G. Abd Elhameed. (2021) Krill oil and low-dose aspirin combination mitigates experimentally induced silicosis in rats: role of NF-κB/TGF-β1/MMP-9 pathway. Environmental Science and Pollution Research 28:15, pages 19272-19284.
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Tina M. Sager, Jenny R. Roberts, Christina M. Umbright, Mark Barger, Michael L. Kashon, Jeffrey S. Fedan & Pius Joseph. (2020) Biological effects of inhaled hydraulic fracturing sand dust. V. Pulmonary inflammatory, cytotoxic and oxidant effects. Toxicology and Applied Pharmacology 408, pages 115280.
Crossref
Kristine Krajnak, Hong Kan, Kristen A. Russ, Walter McKinney, Stacey Waugh, Wen Zheng, Michael L. Kashon, Claud Johnson, Jared Cumpston & Jeffrey S. Fedan. (2020) Biological effects of inhaled hydraulic fracturing sand dust. VI. Cardiovascular effects. Toxicology and Applied Pharmacology 406, pages 115242.
Crossref
Tapati Chakraborti, Jaganmay Sarkar, Pijush Kanti Pramanik & Sajal Chakraborti. 2020. Oxidative Stress in Lung Diseases. Oxidative Stress in Lung Diseases 271 293 .
Ting Zhou, Qimei Yu, Hui Lin, Zhenyu Wang, Guoqing Fu, Lu Lei, Yuqin Shi, Ling Zhang, Lingzhi Qin & Yuewei Liu. (2019) The Role of CTGF in Inflammatory Responses Induced by Silica Particles in Human Bronchial Epithelial Cells. Lung 197:6, pages 783-791.
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Zhao-qiang Zhang, Bo Shao, Gui-zhi Han, Gen-yi Liu, Chun-zhi Zhang & Li Lin. (2019) Location and dynamic changes of inflammation, fibrosis, and expression levels of related genes in SiO<sub>2</sub>-induced pulmonary fibrosis in rats <i>in vivo</i>. Journal of Toxicologic Pathology 32:4, pages 253-260.
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Yoshimi Kobayashi, Akinori Shimada, Takehito Morita, Kenichiro Inoue & Hirohisa Takano. (2018) A Pathological Study of Acute Pulmonary Toxicity Induced by Inhaled Kanto Loam Powder. International Journal of Molecular Sciences 19:2, pages 416.
Crossref
Lei Bao, Changfu Hao, Suna Liu, Lin Zhang, Juan Wang, Di Wang, Yiping Li & Wu Yao. (2018) Dendritic cells trigger imbalance of Th1/Th2 cells in silica dust exposure rat model via MHC-II, CD80, CD86 and IL-12 . RSC Advances 8:46, pages 26108-26115.
Crossref
Mohammad Shoeb, Pius Joseph, Vamsi Kodali, Gul Mustafa, Breanne Y. Farris, Christina Umbright, Jenny R. Roberts, Aaron Erdely & James M. Antonini. (2017) Silica inhalation altered telomere length and gene expression of telomere regulatory proteins in lung tissue of rats. Scientific Reports 7:1.
Crossref
Pius Joseph. (2017) Transcriptomics in toxicology. Food and Chemical Toxicology 109, pages 650-662.
Crossref

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