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Inhalation Toxicology
International Forum for Respiratory Research
Volume 10, 1998 - Issue 1
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Research Article

IN VITRO HEPATIC METABOLISM OF PCBTF: DEVELOPMENT OF Vmax AND Km VALUES AND PARTITION COEFFICIENTS AND THEIR USE IN AN INHALATION PBPK MODEL

B. Knaak James Occidental Chemical Corporation, Dallas, Texas, USA
,
W. Smith Ladd Department of Pharmacology and Toxicology, State University of New York, Buffalo, New York, USA
,
D. Fitzpatrick Richard Pharmacol LSR, East Millstone, New Jersey, USA
,
R. Olson James Occidental Chemical Corporation, Dallas, Texas, USA
&
E. Newton Paul Occidental Chemical Corporation, Dallas, Texas, USA
Pages 65-85 | Published online: 01 Oct 2008

Citations (8)

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Read on this site (1)

E. Newton Paul, F. Bolte Henry, R. Richter Ward, B. Knaak James & W. Smith Ladd. (1998) INHALATION TOXICITY, NEUROTOXICITY, AND TOXICOKINETIC STUDIES OF p-CHLOROBENZOTRIFLUORIDE. Inhalation Toxicology 10:1, pages 33-48.
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Articles from other publishers (7)

Michael H Abraham, Joelle MR Gola, Adam Ibrahim, William E AcreeJrJr & Xiangli Liu. (2014) The prediction of blood-tissue partitions, water-skin partitions and skin permeation for agrochemicals. Pest Management Science 70:7, pages 1130-1137.
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Michael H. Abraham, Adam Ibrahim & William E. AcreeJr.Jr.. (2007) Air to liver partition coefficients for volatile organic compounds and blood to liver partition coefficients for volatile organic compounds and drugs. European Journal of Medicinal Chemistry 42:6, pages 743-751.
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Michael H. Abraham & Adam Ibrahim. (2006) Air to fat and blood to fat distribution of volatile organic compounds and drugs: Linear free energy analyses. European Journal of Medicinal Chemistry 41:12, pages 1430-1438.
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Michael H. Abraham, Adam Ibrahim & William E. AcreeJr.Jr.. (2006) Air to brain, blood to brain and plasma to brain distribution of volatile organic compounds: linear free energy analyses. European Journal of Medicinal Chemistry 41:4, pages 494-502.
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Alan R. Katritzky, Minati Kuanar, Dan C. Fara, Mati Karelson, William E. AcreeJr.Jr., Vitaly P. Solov’ev & Alexandre Varnek. (2005) QSAR modeling of blood:air and tissue:air partition coefficients using theoretical descriptors. Bioorganic & Medicinal Chemistry 13:23, pages 6450-6463.
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Alan R. Katritzky, Minati Kuanar, Dan C. Fara, Mati Karelson & William E. AcreeJr.Jr.. (2004) QSPR treatment of rat blood:air, saline:air and olive oil:air partition coefficients using theoretical molecular descriptors. Bioorganic & Medicinal Chemistry 12:17, pages 4735-4748.
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James J. Maul, Philip J. Ostrowski, Gregg A. Ublacker, Bruno Linclau & Dennis P. Curran. 1999. Modern Solvents in Organic Synthesis. Modern Solvents in Organic Synthesis 79 105 .

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