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Journal of Liposome Research Volume 29, 2019 - Issue 4
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Research Articles

Metformin hydrochloride and wound healing: from nanoformulation to pharmacological evaluation

Mohamed S. El-RidyPharmaceutical Technology Department, Pharmaceutical industries Research Division, National Research Centre, Dokki, Cairo, Egypt; Correspondence[email protected]
,
Soad A. YehiaDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt;
,
Ibrahim ElsayedDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt; ;Department of Pharmaceutical Sciences, College of Pharmacy, Gulf Medical University, Ajman, UAE;
,
Mostafa M. YounisPharmaceutical Technology Department, Pharmaceutical industries Research Division, National Research Centre, Dokki, Cairo, Egypt;
,
Rehab F. Abdel-RahmanPharmacology Department, Medical Research Division, National Research Centre, Dokki, Cairo, Egypt
&
Menna Ahmed El-GamilPharmaceutical Technology Department, Pharmaceutical industries Research Division, National Research Centre, Dokki, Cairo, Egypt;
Pages 343-356 | Received 09 Aug 2018, Accepted 01 Dec 2018, Published online: 31 Jan 2019

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Fiammetta Nigro, Cristal dos Santos Cerqueira Pinto, Elisabete Pereira dos Santos & Claudia Regina Elias Mansur. (2022) Niosome-based hydrogel as a potential drug delivery system for topical and transdermal applications. International Journal of Polymeric Materials and Polymeric Biomaterials 71:6, pages 444-461.
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Articles from other publishers (17)

Mohd Hussain, Abdul Hafeez & Shom Prakash Kushwaha. (2023) Nanoformulation mediated transdermal delivery of anti-diabetic drugs: an updated review. Intelligent Pharmacy 1:4, pages 192-200.
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Elnaz Salmani-Javan, Davoud Jafari-Gharabaghlou, Esat Bonabi & Nosratollah Zarghami. (2023) Fabricating niosomal-PEG nanoparticles co-loaded with metformin and silibinin for effective treatment of human lung cancer cells. Frontiers in Oncology 13.
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Samrat Chauhan, Rishabh Chalotra, Akshay Rathi, Monika Saini, Shweta Deol, Mehak Lard & Sumeet Gupta. (2023) Current Approaches in Healing of Wounds in Diabetes and Diabetic Foot Ulcers. Current Bioactive Compounds 19:3.
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Jun Zhou, Jiawei Mei, Quan Liu, Dongdong Xu, Xiaoli Wang, Xianzuo Zhang, Wanbo Zhu, Chen Zhu & Jiaxing Wang. (2023) Spatiotemporal On–Off Immunomodulatory Hydrogel Targeting NLRP3 Inflammasome for the Treatment of Biofilm‐Infected Diabetic Wounds. Advanced Functional Materials 33:12.
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Saibhargav Narisepalli, Shubham A. Salunkhe, Deepak Chitkara & Anupama Mittal. (2023) Asiaticoside polymeric nanoparticles for effective diabetic wound healing through increased collagen biosynthesis: In-vitro and in-vivo evaluation. International Journal of Pharmaceutics 631, pages 122508.
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Nourhan A. Elzayat, Haidy Abbas, Maged W. Helmy & Doaa A. Habib. (2022) Phyto-therapeutic and nanomedicinal approaches: A new hope for management of Alzheimer’s disease. International Journal of Pharmaceutics 627, pages 122213.
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Hermann A.M. Mucke. (2022) Drug Repurposing Patent Applications March–June 2022. ASSAY and Drug Development Technologies 20:6, pages 286-293.
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Ankit Awasthi, Sukriti Vishwas, Monica Gulati, Leander Corrie, Jaskiran Kaur, Rubiya Khursheed, Aftab Alam, Faris F.Aba Alkhayl, Farhan Riyazuddin Khan, Sivagurunathan Nagarethinam, Rajan Kumar, K.R. Arya, Bimlesh Kumar, Dinesh Kumar Chellappan, Gaurav Gupta, Kamal Dua & Sachin Kumar Singh. (2022) Expanding arsenal against diabetic wounds using nanomedicines and nanomaterials: Success so far and bottlenecks. Journal of Drug Delivery Science and Technology 74, pages 103534.
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Bhaskar Kandregula, Saibhargav Narisepalli, Deepak Chitkara & Anupama Mittal. (2022) Exploration of Lipid-Based Nanocarriers as Drug Delivery Systems in Diabetic Foot Ulcer. Molecular Pharmaceutics 19:7, pages 1977-1998.
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Shidrokh Abootorabi, Jafar Akbari, Majid Saeedi, Mohammad Seyedabadi, Mohammad Ranaee, Kofi Asare-Addo & Ali Nokhodchi. (2022) Atorvastatin Entrapped Noisome (Atrosome): Green Preparation Approach for Wound Healing. AAPS PharmSciTech 23:3.
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Sheikh Tanzina Haque, Subbroto Kumar Saha, Md. Enamul Haque & Nirupam Biswas. (2021) Nanotechnology-based therapeutic applications: in vitro and in vivo clinical studies for diabetic wound healing . Biomaterials Science 9:23, pages 7705-7747.
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Yasmin A. Eltellawy, Maha El-Kayal, Rehab F. Abdel-Rahman, Salwa Salah & Dalia S. Shaker. (2021) Optimization of transdermal atorvastatin calcium – Loaded proniosomes: Restoring lipid profile and alleviating hepatotoxicity in poloxamer 407-induced hyperlipidemia. International Journal of Pharmaceutics 593, pages 120163.
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Mohammad Kashif Iqubal, Sadaf Saleem, Ashif Iqubal, Aiswarya Chaudhuri, Faheem Hyder Pottoo, Javed Ali & Sanjula Baboota. (2020) Natural, Synthetic and their Combinatorial Nanocarriers Based Drug Delivery System in the Treatment Paradigm for Wound Healing Via Dermal Targeting. Current Pharmaceutical Design 26:36, pages 4551-4568.
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Hosna Zare, Majid Rezayi, Ehsan Aryan, Zahra Meshkat, Behnaz hatamluyi, Alireza Neshani, Kiarash Ghazvini, Mohammad Derakhshan & Mojtaba Sankian. (2020) Nanotechnology‐driven advances in the treatment of diabetic wounds. Biotechnology and Applied Biochemistry.
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Mohamad Taleuzzaman, Chandra Kala, Iqra Rahat, Sadaf Jamal Gilani, Vinay Kumar & Syed Sarim Imam. (2020) A Review on Experimental Methods for Diabetes Induction and Therapeutic Efficacy of Anti-diabetic Drug Loaded Nanoformulation. Current Drug Therapy 15:5, pages 436-447.
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Hesham M. Tawfeek, Doaa A. E. Abou-Taleb, Dalia M. Badary, Mohamed Ibrahim & Ahmed A. H. Abdellatif. (2019) Pharmaceutical, clinical, and immunohistochemical studies of metformin hydrochloride topical hydrogel for wound healing application. Archives of Dermatological Research 312:2, pages 113-121.
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Rehab F. Abdel-Rahman, Shahira M. Ezzat, Hanan A. Ogaly, Reham M. Abd-Elsalam, Alyaa F. Hessin, Mostafa I. Fekry, Dina F. Mansour & Shanaz O. Mohamed. (2020) Ficus deltoidea extract down-regulates protein tyrosine phosphatase 1B expression in a rat model of type 2 diabetes mellitus: a new insight into its antidiabetic mechanism . Journal of Nutritional Science 9.
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