Advanced search
Publication Cover
Bioscience, Biotechnology, and Biochemistry Volume 79, 2015 - Issue 7
Journal homepage
1,493
Views
9
CrossRef citations to date
0
Altmetric
Organic Chemistry

Production of new amilorides as potent inhibitors of mitochondrial respiratory complex I

Masatoshi MuraiDivision of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan
,
Sayako HabuDivision of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan
,
Sonomi MurakamiDivision of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan
,
Takeshi ItoDivision of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan
&
Hideto MiyoshiDivision of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, JapanCorrespondence[email protected]
Pages 1061-1066 | Received 27 Nov 2014, Accepted 10 Jan 2015, Published online: 03 Mar 2015

Citations (9)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Masatoshi Murai. (2020) Exploring the binding pocket of quinone/inhibitors in mitochondrial respiratory complex I by chemical biology approaches. Bioscience, Biotechnology, and Biochemistry 84:7, pages 1322-1331.
Read now

Articles from other publishers (8)

Yusei Shinohara, Yuki Komiya, Kashin Morimoto, Yoshio Endo, Minoru Terashima, Takeshi Suzuki, Takahisa Takino, Itasu Ninomiya, Hisatsugu Yamada & Yoshihiro Uto. (2024) Development of UTX-143, a selective sodium-hydrogen exchange subtype 5 inhibitor, using amiloride as a lead compound. Bioorganic & Medicinal Chemistry 99, pages 117603.
Crossref
Noah H. Somberg, João Medeiros‐Silva, Hyunil Jo, Jun Wang, William F. DeGrado & Mei Hong. (2023) Hexamethylene amiloride binds the SARS‐CoV‐2 envelope protein at the protein–lipid interface. Protein Science 32:10.
Crossref
Lixin Shen, Lang Gao, Mengjiao Yang, Jian Zhang, Yulu Wang, Yuqi Feng, Liping Wang & Shiwei Wang. (2021) Deletion of the PA4427-PA4431 Operon of Pseudomonas aeruginosa PAO1 Increased Antibiotics Resistance and Reduced Virulence and Pathogenicity by Affecting Quorum Sensing and Iron Uptake. Microorganisms 9:5, pages 1065.
Crossref
Shinpei Uno, Hironori Kimura, Masatoshi Murai & Hideto Miyoshi. (2019) Exploring the quinone/inhibitor-binding pocket in mitochondrial respiratory complex I by chemical biology approaches. Journal of Biological Chemistry 294:2, pages 679-696.
Crossref
Hideto Miyoshi & Masatoshi Murai. (2017) Action mechanism of the inhibitors of mitochondrial respiratory complex I based on structure-activity relationship (SAR) studies. Japanese Journal of Pesticide Science 42:1, pages 44-48.
Crossref
Neeraj N. Patwardhan, Laura R. Ganser, Gary J. Kapral, Christopher S. Eubanks, Janghyun Lee, Bharathwaj Sathyamoorthy, Hashim M. Al-Hashimi & Amanda E. Hargrove. (2017) Amiloride as a new RNA-binding scaffold with activity against HIV-1 TAR. MedChemComm 8:5, pages 1022-1036.
Crossref
Takeshi Ito, Masatoshi Murai, Hironobu Morisaka & Hideto Miyoshi. (2015) Identification of the Binding Position of Amilorides in the Quinone Binding Pocket of Mitochondrial Complex I. Biochemistry 54:23, pages 3677-3686.
Crossref
Masatoshi Murai, Sonomi Murakami, Takeshi Ito & Hideto Miyoshi. (2015) Amilorides Bind to the Quinone Binding Pocket of Bovine Mitochondrial Complex I. Biochemistry 54:17, pages 2739-2746.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.