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Food & Nutrition Science

Absorption and plasma kinetics of collagen tripeptide after peroral or intraperitoneal administration in ratsFootnote

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Pages 2026-2033 | Received 05 Jan 2015, Accepted 04 Jun 2015, Published online: 09 Jul 2015

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Jihyun Won, Juhyung Kang, Keumhan Noh, Hee‐Chul Chung & Wonku Kang. (2023) Pharmacokinetics of collagen dipeptides (Gly–Pro and Pro–Hyp) and tripeptides (Gly–Pro–Hyp) in rats. Journal of Food Science.
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Wei Liu, Wenning Yang, Xueyan Li, Dongying Qi, Hongjiao Chen, Huining Liu, Shuang Yu, Guopeng Wang & Yang Liu. (2022) Evaluating the Properties of Ginger Protease-Degraded Collagen Hydrolysate and Identifying the Cleavage Site of Ginger Protease by Using an Integrated Strategy and LC-MS Technology. Molecules 27:15, pages 5001.
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Mun-Hoe Lee, Hyeong-Min Kim, Hee-Chul Chung, Do-Un Kim & Jin-Hee Lee. (2021) Low-Molecular-Weight Collagen Peptide Ameliorates Osteoarthritis Progression through Promoting Extracellular Matrix Synthesis by Chondrocytes in a Rabbit Anterior Cruciate Ligament Transection Model. Journal of Microbiology and Biotechnology 31:10, pages 1401-1408.
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Ran WATANABE, Mana YAMAGUCHI, Kyosuke WATANABE, Muneshige SHIMIZU, TAKAHASHI Azusa, Hideyuki SONE & Shin KAMIYAMA. (2021) Effects of Collagen Peptide Administration on Visceral Fat Content in High-Fat Diet-Induced Obese Mice. Journal of Nutritional Science and Vitaminology 67:1, pages 57-62.
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Luana Quassinti, Giuseppe Gianfranceschi, Antonio Cipiciani, Andrea Caporale, Menotti Ruvo & Massimo Bramucci. (2020) AcGly–Phe–Asn(OH) and AcGly–Phe–Asn(NH2) tripeptides selectively affect the proliferation rate of MDA-MB 231 and HuDe cells. Molecular Biology Reports 47:5, pages 4009-4014.
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Gabriel Aguirre-Cruz, Arely León-López, Verónica Cruz-Gómez, Rubén Jiménez-Alvarado & Gabriel Aguirre-Álvarez. (2020) Collagen Hydrolysates for Skin Protection: Oral Administration and Topical Formulation. Antioxidants 9:2, pages 181.
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Yuki Taga, Masashi Kusubata, Kiyoko Ogawa-Goto, Shunji Hattori & Noriko Funato. (2018) Collagen-derived X-Hyp-Gly-type tripeptides promote differentiation of MC3T3-E1 pre-osteoblasts. Journal of Functional Foods 46, pages 456-462.
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Suqin Zhu, Min Huang, Guangxin Feng, Yu Miao, Haohao Wu, Mingyong Zeng & Yangming Martin Lo. (2018) Gelatin versus its two major degradation products, prolyl-hydroxyproline and glycine, as supportive therapy in experimental colitis in mice. Food Science & Nutrition 6:4, pages 1023-1031.
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Yoshihiro OSAWA, Takafumi MIZUSHIGE, Sayuri JINNO, Fumihito SUGIHARANaoki INOUEHideyuki TANAKA & Yukihito KABUYAMA. (2018) <b>Absorption and metabolism of orally administered collagen hydrolysates evaluated by the vascularly perfused rat intestine and liver </b><i><b>in </b></i><i><b>situ </b></i>. Biomedical Research 39:1, pages 1-11.
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Amiko Hakuta, Yukie Yamaguchi, Tomoko Okawa, Shoko Yamamoto, Yasuo Sakai & Michiko Aihara. (2017) Anti-inflammatory effect of collagen tripeptide in atopic dermatitis. Journal of Dermatological Science 88:3, pages 357-364.
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Yuki Taga, Masashi Kusubata, Kiyoko Ogawa-Goto & Shunji Hattori. (2017) Identification of Collagen-Derived Hydroxyproline (Hyp)-Containing Cyclic Dipeptides with High Oral Bioavailability: Efficient Formation of Cyclo(X-Hyp) from X-Hyp-Gly-Type Tripeptides by Heating. Journal of Agricultural and Food Chemistry 65:43, pages 9514-9521.
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Keita Kamikura, Tsutomu Minatoya, Michiko Terada-Nakaishi, Shoko Yamamoto, Yasuo Sakai, Toshitake Furusawa, Yuta Matsushima & Hidero Unuma. (2017) Enhanced bone formation in the vicinity of porous β-TCP scaffolds exhibiting slow release of collagen-derived tripeptides. Journal of Materials Science: Materials in Medicine 28:9.
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M. Parent, A. Boudier, P. Maincent, S. Gibot, H. Ait-Oufella, A. Boufenzer, L. Jolly, M. Derive, M. Kouach, J.-F. Goossens, P. Leroy & I. Clarot. (2017) LR12-peptide quantitation in whole blood by RP-HPLC and intrinsic fluorescence detection: Validation and pharmacokinetic study. Biomedical Chromatography 31:5, pages e3877.
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Naohisa Tomosugi, Shoko YamamotoMasayoshi Takeuchi, Hideto Yonekura, Yasuhito Ishigaki, Noriaki NumataShogo Katsuda & Yasuo Sakai. (2017) Effect of Collagen Tripeptide on Atherosclerosis in Healthy Humans. Journal of Atherosclerosis and Thrombosis 24:5, pages 530-538.
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Hongdong Song, Mengfei Meng, Xiaofeng Cheng, Bo Li & Chengtao Wang. (2017) The effect of collagen hydrolysates from silver carp (Hypophthalmichthys molitrix) skin on UV-induced photoaging in mice: molecular weight affects skin repair. Food & Function 8:4, pages 1538-1546.
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Sneha B. Sontakke, Jin-hee Jung, Zhe Piao & Hye Jin Chung. (2016) Orally Available Collagen Tripeptide: Enzymatic Stability, Intestinal Permeability, and Absorption of Gly-Pro-Hyp and Pro-Hyp. Journal of Agricultural and Food Chemistry 64:38, pages 7127-7133.
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Yuki Taga, Masashi Kusubata, Kiyoko Ogawa-Goto & Shunji Hattori. (2016) Efficient Absorption of X-Hydroxyproline (Hyp)-Gly after Oral Administration of a Novel Gelatin Hydrolysate Prepared Using Ginger Protease. Journal of Agricultural and Food Chemistry 64:14, pages 2962-2970.
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Fumitaka HayasakaShoko YamamotoYasuo Sakai. (2016) Production Method for Cyclic Dipeptide Derived from Native Collagen. Food Science and Technology Research 22:4, pages 477-483.
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Shoko YamamotoKisaburo DeguchiMasamichi OnumaNoriaki NumataYasuo Sakai. (2016) Absorption and Urinary Excretion of Peptides after Collagen Tripeptide Ingestion in Humans. Biological & Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 39:3, pages 428-434.
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